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FKVMFYSPRIAPNTGNAIRMVAGTGCELHLVEPLGFDLSEPKLRRAGLDYHDLASVTVHPDLDSAWAAVT PARVFAFTAHATASFADVAYRPGDVLMFGPEPTGLDAATLADPHITAQVRIPLLAGRRSLNLSNAAAVAV YEAWRQQGFSGAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1533 | - | - | 100% (154) | tRNA/rRNA methyltransferase (SpoU) |
| M. vanbaalenii PYR-1 | Mvan_3325 | - | 8e-07 | 32.39% (142) | tRNA/rRNA methyltransferase (SpoU) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3401 | spoU | 5e-70 | 81.82% (154) | tRNA/rRNA methylase SpoU |
| M. gilvum PYR-GCK | Mflv_4891 | - | 2e-75 | 86.36% (154) | tRNA/rRNA methyltransferase (SpoU) |
| M. tuberculosis H37Rv | Rv3366 | spoU | 5e-70 | 81.82% (154) | tRNA/rRNA methylase SpoU |
| M. leprae Br4923 | MLBr_00419 | - | 2e-66 | 75.97% (154) | putative tRNA/rRNA methyltransferase |
| M. abscessus ATCC 19977 | MAB_3702 | - | 3e-66 | 74.68% (154) | tRNA/rRNA methyltransferase SpoU |
| M. marinum M | MMAR_1163 | spoU | 4e-71 | 82.47% (154) | tRNA/rRNA methyltransferase SpoU |
| M. avium 104 | MAV_4333 | - | 3e-73 | 83.66% (153) | RNA methyltransferase, TrmH family protein, group 2 |
| M. smegmatis MC2 155 | MSMEG_1636 | - | 6e-74 | 83.77% (154) | RNA methyltransferase, TrmH family protein, group 2 |
| M. thermoresistible (build 8) | TH_2120 | spoU | 3e-69 | 81.05% (153) | PROBABLE tRNA/rRNA METHYLASE SPOU (tRNA/rRNA |
| M. ulcerans Agy99 | MUL_2852 | spoU | 2e-70 | 81.82% (154) | tRNA/rRNA methyltransferase SpoU |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1163|M.marinum_M --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MUL_2852|M.ulcerans_Agy99 --------------MFKLLFYSPRIAPNTGNAIRTAAATGCELHLVEPLG
MAV_4333|M.avium_104 --------------MFKLMFVSPRIAPNTGNAIRTAAATGCELHLVEPMG
Mb3401|M.bovis_AF2122/97 --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
Rv3366|M.tuberculosis_H37Rv --------------MFRLLFVSPRIAPNTGNAIRTCAATGCELHLVEPLG
MLBr_00419|M.leprae_Br4923 ----------MISKMFRLLFYTPRIPPNTGNAIRTAAVTGCALHLVEPIG
Mflv_4891|M.gilvum_PYR-GCK --------------MFNVLFYSPRIAPNTGNAIRMVAGTGCALHLVEPLG
Mvan_1533|M.vanbaalenii_PYR-1 --------------MFKVMFYSPRIAPNTGNAIRMVAGTGCELHLVEPLG
MSMEG_1636|M.smegmatis_MC2_155 --------------MFRVMFFSPRIAPNTGNAIRMVAATGCELHLVHPLG
TH_2120|M.thermoresistible__bu VCEQSPIAGWDHRLVFRVMFYSPRIPPNTGNAIRMVAATGAELHLVDPL-
MAB_3702|M.abscessus_ATCC_1997 --------------MFHILFHEPRIAPNTGNAIRMVAGTGCELHLVQPL-
:*.::* ***.******** * **. ****.*:
MMAR_1163|M.marinum_M FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MUL_2852|M.ulcerans_Agy99 FDLSEPKLRRAGLDYHDLASVTVHGSLTQAWDALLPARVFAFTAGASVTF
MAV_4333|M.avium_104 FDLSEPKLRRAGLDYHDLASVTVHASLAAAWDALTPARVVAFTSHAPASF
Mb3401|M.bovis_AF2122/97 FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
Rv3366|M.tuberculosis_H37Rv FDLSEPKLRRAGLDYHDLASVTVHASLAHAWEALSPARVFAFTAQATTLF
MLBr_00419|M.leprae_Br4923 FDLSNPKLRRAGLDYHDLASVTVHTSLSEAWNALSPARVFAFSTLANTLF
Mflv_4891|M.gilvum_PYR-GCK FDLSEPKLRRAGLDYHDLASVTVHADLGAAWSVLMPARVFAFTAHAATSF
Mvan_1533|M.vanbaalenii_PYR-1 FDLSEPKLRRAGLDYHDLASVTVHPDLDSAWAAVTPARVFAFTAHATASF
MSMEG_1636|M.smegmatis_MC2_155 FDLSEPKLRRAGLDYHDLASVTVHDDLPSAWQALMPARVYVFTAHASTPF
TH_2120|M.thermoresistible__bu FDLSEPKLRRAGLDYHDLASVSVHTDLDAAWAALQPRRVFAFTVRAETTY
MAB_3702|M.abscessus_ATCC_1997 FDLSEAKVRRAGLDYHDMASVTVHENLSAAWKTLKPQRVYAFTAHASVTY
****:.*:*********:***:** .* ** .: * ** .*: * . :
MMAR_1163|M.marinum_M SDVDFRPGDVLMFGPEPTGLDAATLADAHITQQVRIPMLAGRRSLNLANA
MUL_2852|M.ulcerans_Agy99 SDVDFRPGDVLMFGPEPTGLHAATLADAHITQQVRIPMLAGRRSLNLANA
MAV_4333|M.avium_104 AELRYRPGDVLMFGPEPTGLDAATLADPHVTTQVRIPMLAGRRSLNLSNA
Mb3401|M.bovis_AF2122/97 TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
Rv3366|M.tuberculosis_H37Rv TNVGYRAGDVLMFGPEPTGLDEATLADTHITGQVRIPMLAGRRSLNLSNA
MLBr_00419|M.leprae_Br4923 TDVSYQAGDVLMFGPEPTGLDAATLADDHITQQVRIPMLSGRRSLNLSNA
Mflv_4891|M.gilvum_PYR-GCK AGVGYEPGDVLMFGPEPTGLDEATLADPHITGQVRIPMLSGRRSLNLSNA
Mvan_1533|M.vanbaalenii_PYR-1 ADVAYRPGDVLMFGPEPTGLDAATLADPHITAQVRIPLLAGRRSLNLSNA
MSMEG_1636|M.smegmatis_MC2_155 TDIAYRPGDVLMFGPEPTGLDEQTLADPHITEQIRIPMLAGRRSLNLSNA
TH_2120|M.thermoresistible__bu VDIHYQPGDVLMFGPEPTGLDAETLADPHITAEVSIPMLPGRRSLNLSNA
MAB_3702|M.abscessus_ATCC_1997 TDIAYQPGDVLLFGPEPTGLDAEVLADPHITEKVRIPLLPGRRSLNLSNA
: :..****:********. .*** *:* :: **:*.*******:**
MMAR_1163|M.marinum_M AAVAVYEAWRQHGYPGAL
MUL_2852|M.ulcerans_Agy99 AAVAVYEAWRQHGYPGAL
MAV_4333|M.avium_104 AAIAVYEAWRQHGYAGAT
Mb3401|M.bovis_AF2122/97 AAVAVYEAWRQHGFAGAV
Rv3366|M.tuberculosis_H37Rv AAVAVYEAWRQHGFAGAV
MLBr_00419|M.leprae_Br4923 AAVAVYEAWRQHGYAGLV
Mflv_4891|M.gilvum_PYR-GCK AAVAVYEAWRQHGFAGAV
Mvan_1533|M.vanbaalenii_PYR-1 AAVAVYEAWRQQGFSGAV
MSMEG_1636|M.smegmatis_MC2_155 AAVAAYEAWRQHGFPGAV
TH_2120|M.thermoresistible__bu AAVAVYEAWRQHGFAGA-
MAB_3702|M.abscessus_ATCC_1997 AAIAAYEAWRQHDFAGSV
**:*.******:.:.*