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VMPVQRVVRAVATALAVVVVLGTGLAWTNVRSFEGGIFHMSAPSLGHGADDGAIDILLVGLDSRTDAHGN PLTPEELATLRAGDEEATNTDTIILVRIPNNGRSATAISIPRDSYVQAPGLGKTKINGVYGQTRETKRAG LVQAGASAAEAAAAGTEAGREALIKTVADLTGVTVDHYAEIGLLGFALITDALGGVDVCLNGPVYEPLSG ADFPAGRQKLTGPQALAFVRQRHELPRGDLDRVVRQQAVMASLAHRVISGKTLSSPTTVRRLEQAVQRSV VLSSGWNIIDFVQQLQQLTGGNVAFATIPVLDGSGWSDDGMQSVVRVDPHQVADWVGSLLNEQNEGKTAE LAYAPAKTTADVVNDTDINGLAAAVSDVLSAKGFTTGSVGNNEAGHVKLSQVRAVTTDDLGAQQVAKELG GLPVVADTSIPSGSVRVVLSNDYSGPGSGLGGAMAPAHASNPGYSDTAPPPSPILTAGSDQPECIN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2613 | - | - | 100% (486) | hypothetical protein MUL_2613 |
| M. ulcerans Agy99 | MUL_4040 | cpsA | 1e-63 | 36.62% (456) | membrane protein CpsA |
| M. ulcerans Agy99 | MUL_5013 | - | 2e-31 | 33.44% (302) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3295 | - | 0.0 | 83.33% (498) | hypothetical protein Mb3295 |
| M. gilvum PYR-GCK | Mflv_4737 | - | 0.0 | 68.15% (493) | cell envelope-related transcriptional attenuator |
| M. tuberculosis H37Rv | Rv3267 | - | 0.0 | 83.33% (498) | hypothetical protein Rv3267 |
| M. leprae Br4923 | MLBr_00750 | - | 0.0 | 77.91% (489) | hypothetical protein MLBr_00750 |
| M. abscessus ATCC 19977 | MAB_3614 | - | 1e-160 | 59.55% (487) | hypothetical protein MAB_3614 |
| M. marinum M | MMAR_1274 | - | 0.0 | 99.79% (485) | hypothetical protein MMAR_1274 |
| M. avium 104 | MAV_4232 | - | 0.0 | 81.70% (481) | cell envelope-related function transcriptional attenuator |
| M. smegmatis MC2 155 | MSMEG_1824 | - | 0.0 | 70.79% (493) | transcriptional regulator, LytR family protein |
| M. thermoresistible (build 8) | TH_3471 | - | 1e-177 | 64.14% (488) | PUTATIVE cell envelope-related transcriptional attenuator |
| M. vanbaalenii PYR-1 | Mvan_1726 | - | 0.0 | 69.57% (493) | cell envelope-related transcriptional attenuator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4737|M.gilvum_PYR-GCK -----------------------------MPAAHMLR------AVSVALA
Mvan_1726|M.vanbaalenii_PYR-1 -----------------------------MPAAHLVR------AISVAMA
MSMEG_1824|M.smegmatis_MC2_155 ----------------------------------MIR------SIAVAAA
TH_3471|M.thermoresistible__bu ------------------------------VPARLIR------ALAVATA
MUL_2613|M.ulcerans_Agy99 ----------------------------MMPVQRVVR------AVATALA
MMAR_1274|M.marinum_M -----------------------------MPVQRVVR------AVATALA
Mb3295|M.bovis_AF2122/97 ----------------------------MMSAQRVVRTVRTARAISTALA
Rv3267|M.tuberculosis_H37Rv ----------------------------MMSAQRVVRTVRTARAISTALA
MLBr_00750|M.leprae_Br4923 -----------------------------MPVQRVVR------AVVTALT
MAV_4232|M.avium_104 -------------------------------------------MIATALT
MAB_3614|M.abscessus_ATCC_1997 MPGEGPAGEEWTDIVTDPHARRASGSSQAEPPRPLWR------GIATLAA
: . :
Mflv_4737|M.gilvum_PYR-GCK VAIVIGTGVAWGKIRSFEAGINHINPI-ALGGEG--EDGAIDILLVGSDS
Mvan_1726|M.vanbaalenii_PYR-1 VVVVLGTGIAWGKIRSFESGINHINPV-ALGEGG--EDGAIDILLVGSDS
MSMEG_1824|M.smegmatis_MC2_155 SAVVLGTGVAWTQVRSFESGINHISSS-ALGEGG--EDGAIDILLVGIDS
TH_3471|M.thermoresistible__bu VVIVLSTGVAWSRIRAFEAGISQISSP-LLGQGG--EDGAVDILLVGMDS
MUL_2613|M.ulcerans_Agy99 VVVVLGTGLAWTNVRSFEGGIFHMSAP-SLGHGA--DDGAIDILLVGLDS
MMAR_1274|M.marinum_M VVVVLGTGLAWTNVRSFEGGIFHMSAP-SLGHGA--DDGAIDILLVGLDS
Mb3295|M.bovis_AF2122/97 VAIVLGTGVAWSSVRSFEDGIFHMSAP-SLGHGG--DDGAIDILLVGLDS
Rv3267|M.tuberculosis_H37Rv VAIVLGTGVAWSSVRSFEDGIFHMSAP-SLGHGG--DDGAIDILLVGLDS
MLBr_00750|M.leprae_Br4923 LAIVLGTGITWTSFRSFEDGIFHMSAP-SLGKGG--NDGAIDILLVGLDS
MAV_4232|M.avium_104 LAVVLGTGIAWSNVRSFEDGIFHMSAP-SLGKGG--DDGAIDILLVGLDS
MAB_3614|M.abscessus_ATCC_1997 VAVMVITGAAWGKIGNIDPNIARFDLPGLFGNAGKPDDGAIDILMVGVDS
.::: ** :* . :: .* ::. :* . :***:***:** **
Mflv_4737|M.gilvum_PYR-GCK RTDAHGNPLSDQERAMLRAGDEVSTNTDTIILIRIPNNGESATAISIPRD
Mvan_1726|M.vanbaalenii_PYR-1 RTDAHGNPLSDEERAMLRAGDEVSTNTDTIILIRIPNNGQSATAISIPRD
MSMEG_1824|M.smegmatis_MC2_155 RTDAHGNPLSPEELATLRAGDDVSTNTDTIILVRIPNNGTSATAISIPRD
TH_3471|M.thermoresistible__bu RTDAHGNPLSAEELAALRAGNDVATNTDTIVLVRIPNNGRSATAISIPRD
MUL_2613|M.ulcerans_Agy99 RTDAHGNPLTPEELATLRAGDEEATNTDTIILVRIPNNGRSATAISIPRD
MMAR_1274|M.marinum_M RTDAHGNPLTPEELATLRAGDEEATNTDTIILVRIPNNGRSATAISIPRD
Mb3295|M.bovis_AF2122/97 RTDAHGNPLSAEELATLHAGDEEATNTDTIILIRVPNNGKSATAISIPRD
Rv3267|M.tuberculosis_H37Rv RTDAHGNPLSAEELATLHAGDEEATNTDTIILIRVPNNGKSATAISIPRD
MLBr_00750|M.leprae_Br4923 RTDAYGNPLSAEELATLRAGDEEATNTDTIILIRIPNNGKSATAISIPRD
MAV_4232|M.avium_104 RTDAHGNPLSQQELETLRAGDEEATNTDTIILIRIPNNGKSATAISIPRD
MAB_3614|M.abscessus_ATCC_1997 RSDAHGNPLSQEELSMLRAGDETATNTDTIILIRIPNNGKSATAISIPRD
*:**:****: :* *:**:: :******:*:*:**** **********
Mflv_4737|M.gilvum_PYR-GCK SYVEAPGIGKMKINGVYGSVHLEEMKELVEQQGVDPAEAEPEAQAAGREE
Mvan_1726|M.vanbaalenii_PYR-1 SYVESPGIGKLKINGVYGSVHLEKMKELVEEQGVDPAVAEPEAQAAGREQ
MSMEG_1824|M.smegmatis_MC2_155 SYVEAPGWGKMKINGVFGDVKLDRMKQLVEVEGEDPAVAEPEATEAGREK
TH_3471|M.thermoresistible__bu SYVEAPGRGKMKINGVYGEVKFETMKQLVEVQGMDPEVAEPLAVQDARGA
MUL_2613|M.ulcerans_Agy99 SYVQAPGLGKTKINGVYGQTRETKRAGLVQ-AGASAAEAAAAGTEAGREA
MMAR_1274|M.marinum_M SYVQAPGLGKTKINGVYGQTRETKRAGLVQ-AGASAAEAAAAGTEAGREA
Mb3295|M.bovis_AF2122/97 SYVAAPGLGKTKINGVYGQTRETKRAGLVQ-AGASPTEAAAAGTEAGREA
Rv3267|M.tuberculosis_H37Rv SYVAAPGLGKTKINGVYGQTRETKRAGLVQ-AGASPTEAAAAGTEAGREA
MLBr_00750|M.leprae_Br4923 SYVQAPGLGKAKINGVYGQTREAKRASLVR-TGDSAEDAAAQGTEAGREA
MAV_4232|M.avium_104 SYVAAPGLGKTKINGVYGQTREAKRASLVK-AGDSAEDAAAQGTEAGREA
MAB_3614|M.abscessus_ATCC_1997 SYVTIPDGSKGKINGVYGEAKENDRQKRVE-SGETLEAAERESVDAGRSA
*** *. .* *****:*..: *. * * . .*
Mflv_4737|M.gilvum_PYR-GCK LIKTVANLTGVTVDHYAEIGLLGFALITDALGGVDVCLNAPVYEPLSGAD
Mvan_1726|M.vanbaalenii_PYR-1 LIKTVANLTGVTVDHYAEIGLLGFALITDALGGVNVCLNAPVYEPLSGAD
MSMEG_1824|M.smegmatis_MC2_155 LIETVADLTGVTVDHYAEIGLLGFALITDALGGVNVCLNEPVYEPLSGAD
TH_3471|M.thermoresistible__bu LIETVAELTGVTVDHYAEIGLLGFALITDALGGVEVCLKNPVYEPLSGAD
MUL_2613|M.ulcerans_Agy99 LIKTVADLTGVTVDHYAEIGLLGFALITDALGGVDVCLNGPVYEPLSGAD
MMAR_1274|M.marinum_M LIKTVADLTGVTVDHYAEIGLLGFALITDALGGVDVCLNGPVYEPLSGAD
Mb3295|M.bovis_AF2122/97 LIKTVADLTGVTVDHYAEIGLLGFALIADALGGVDVCLKEPVYEPLSGAD
Rv3267|M.tuberculosis_H37Rv LIKTVADLTGVTVDHYAEIGLLGFALIADALGGVDVCLKEPVYEPLSGAD
MLBr_00750|M.leprae_Br4923 LIKTVADLTGVTVDHYAEIGLLGFALIVDALGGVDVCLKDAVFEPMSGAD
MAV_4232|M.avium_104 LIKTVADLTGVTVDHYAEIGLLGFALITDALGGVDVCLKEPVFEPLSGAD
MAB_3614|M.abscessus_ATCC_1997 LIQTVGRLTGVTVDRYAEVSMLGFVLMTDALGGVNVCLNEAVYEPMSGAD
**:**. *******:***:.:***.*:.******:***: .*:**:****
Mflv_4737|M.gilvum_PYR-GCK FPAGWQKLNGTQALSFVRQRHDLPRGDLDRVARQQAAMASMAHEVISSKT
Mvan_1726|M.vanbaalenii_PYR-1 FPAGWQKLNGTQALSFVRQRHDLPRGDLDRVARQQAVMASMAHEVISSKT
MSMEG_1824|M.smegmatis_MC2_155 FPAGWQKLNGPQALSFVRQRHGLPRGDLDRVTRQQAFMASLAHEAISSKT
TH_3471|M.thermoresistible__bu FPAGWQRLDGAQALSFVRQRQDLPRGDLDRVTRQQTVMASLAREVISSKT
MUL_2613|M.ulcerans_Agy99 FPAGRQKLTGPQALAFVRQRHELPRGDLDRVVRQQAVMASLAHRVISGKT
MMAR_1274|M.marinum_M FPAGRQKLTGPQALAFVRQRHELPRGDLDRVVRQQAVMASLAHRVISGKT
Mb3295|M.bovis_AF2122/97 FPAGRQKLNGPQALSFVRQRHDLPRGDLDRVVRQQAVMAALAHRVISGQT
Rv3267|M.tuberculosis_H37Rv FPAGRQKLNGPQALSFVRQRHDLPRGDLDRVVRQQAVMAALAHRVISGQT
MLBr_00750|M.leprae_Br4923 FPAGRQKLNGPQALSFVRQRHELPRGDLDRVVRQQAVMASLVHRVISGQT
MAV_4232|M.avium_104 FPAGPQRLSGPEALSFVRQRHELPRGDLDRVVRQQVVMASLAHRVISGQT
MAB_3614|M.abscessus_ATCC_1997 FPAGPQTLDGPNALSFVRQRHDLPRGDLDRVVRQQVVMSSLAHSALSGGT
**** * * *.:**:*****: *********.***. *:::.: .:*. *
Mflv_4737|M.gilvum_PYR-GCK LSSPSTLSALESAVQRSVVLSEGWDIMDFVEQLQKLAAGNVAFATIPILE
Mvan_1726|M.vanbaalenii_PYR-1 LSSPTTLNNLEDAVQRSVVLSDGWNIMDFVEQLQKLAGGNIAFATIPIVE
MSMEG_1824|M.smegmatis_MC2_155 LSSPATLGRLQDAVQRSVVISDGWDIMDFVSQLQNLAGGNVAFATIPILR
TH_3471|M.thermoresistible__bu LSSPATLDRLQRAIQRSVVLSDGWDVMEFVEQLQGLAAGNIAFATIPIVR
MUL_2613|M.ulcerans_Agy99 LSSPTTVRRLEQAVQRSVVLSSGWNIIDFVQQLQQLTGGNVAFATIPVLD
MMAR_1274|M.marinum_M LSSPTTVRRLEQAVQRSVVLSSGWNIIDFVQQLQQLTGGNVAFATIPVLD
Mb3295|M.bovis_AF2122/97 LSSPATLKRLEQAVQRSVVLSSGWDIMDFVRQLQKLAGGNVAFATIPVLD
Rv3267|M.tuberculosis_H37Rv LSSPATLKRLEQAVQRSVVLSSGWDIMDFVRQLQKLAGGNVAFATIPVLD
MLBr_00750|M.leprae_Br4923 LSNPSTIKHLEQAIQRSVVISSGWNLMDFLKQLQSLADRKVAFATIPVLD
MAV_4232|M.avium_104 LSSPATVKRLEAAVQRSVVISAGWDVMDFVQQMQKLAGGNVAFATIPVLD
MAB_3614|M.abscessus_ATCC_1997 LTNTTTLGKLRDAITRTVVLSQGWDVMDFIQQLQKLSGGNVAFATIPILR
*:..:*: *. *: *:**:* **::::*: *:* *: ::******::
Mflv_4737|M.gilvum_PYR-GCK EAGWSDDGMQSVVRVDPKEVKDWVTSLLNDQDQGKTEELAYSNDKTTVEV
Mvan_1726|M.vanbaalenii_PYR-1 EAGWSDDGMQSVVRVDPAAVKDWVTGLLHDQDEGKTEELTYSNDKTTVEV
MSMEG_1824|M.smegmatis_MC2_155 EDGWSDDGMQSVVRVDPQQVRDWVTGLLQDQDEGKTEELAYSPAKTTVEV
TH_3471|M.thermoresistible__bu EDGWSDDGMQSVVRVDPQQVRDWVSSLLEEQDEGKTEEIAYSRDKTTVEV
MUL_2613|M.ulcerans_Agy99 GSGWSDDGMQSVVRVDPHQVADWVGSLLNEQNEGKTAELAYAPAKTTADV
MMAR_1274|M.marinum_M GSGWSDDGMQSVVRVDPHQVADWVGSLLNEQNEGKTAELAYAPAKTTADV
Mb3295|M.bovis_AF2122/97 GAGWSDDGMQSVVRVDPRQVQDWVVGLLHEQDQGKTDELAYTPAKTTANV
Rv3267|M.tuberculosis_H37Rv GAGWSDDGMQSVVRVDPRQVQDWVVGLLHEQDQGKTDELAYTPAKTTANV
MLBr_00750|M.leprae_Br4923 ETGWSDDGMQSVVRVDPHQVQNFVSGLLHNQAQDKTDELAYTPAKITANV
MAV_4232|M.avium_104 GAGWSDDGMQSVVRVDPHQVADWVGSLLHDQEQGKTEEIAYTPAKTTASV
MAB_3614|M.abscessus_ATCC_1997 EDGWTEDGTQSVVKVDPDQVRSWVSGLLDQQAQGKTEEATYSKDQTTADV
**::** ****:*** * .:* .**.:* :.** * :*: : *..*
Mflv_4737|M.gilvum_PYR-GCK YNDSDVNGLAAAVAHVLTGKGFTQGNVGNNEGPKVTGSQVRAAKVDDMGA
Mvan_1726|M.vanbaalenii_PYR-1 VNDTDINGLAAAVSHVLSGKGFTKGNVGNNDGAKVTASQVQAAKTDDLGA
MSMEG_1824|M.smegmatis_MC2_155 LNGTDVNGLAASVSQVLTQKGFTPGDTGNHEDGPVAGSQVLAATSDDLGA
TH_3471|M.thermoresistible__bu LNGTDINGLAAAVSHVLTSNGFSPGPVGNAEDGPADRTEVRVAKQDDRGA
MUL_2613|M.ulcerans_Agy99 VNDTDINGLAAAVSDVLSAKGFTTGSVGNNEAGHVKLSQVRAVTTDDLGA
MMAR_1274|M.marinum_M VNDTDINGLAAAVSDVLSAKGFTTGSVGNNEAGHVKLSQVRAATTDDLGA
Mb3295|M.bovis_AF2122/97 VNDTDINGLAAAVSKVLSSKGFTTGSVGNNDGDHVPGSQVRAAKADDLGA
Rv3267|M.tuberculosis_H37Rv VNDTDINGLAAAVSKVLSSKGFTTGSVGNNDGDHVPGSQVRAAKADDLGA
MLBr_00750|M.leprae_Br4923 ANDTDINGLAAAVSDILTTKGFIAGSVANNQGSHVKSSQVRAAKSDDLGA
MAV_4232|M.avium_104 VNDTDINGLAAAVSDVLSAKGFATGTVGNNDGGHVKTSQVRAAKSDDLGA
MAB_3614|M.abscessus_ATCC_1997 VNETQINGLAAAVSELLVGKGFTAGKVGNNESDHVGSSQVQAAQQDDVGA
* :::*****:*:.:* :** * ..* : . ::* .. ** **
Mflv_4737|M.gilvum_PYR-GCK QAVALDLGGLEVVEDSSVPPDTVRVVLADDYTGPGAGLDGS--DVTLMGA
Mvan_1726|M.vanbaalenii_PYR-1 QAVAQELGGLPVVENAQVPQGSVRVVLAADYTGPGAGLDGS--DVTLMGA
MSMEG_1824|M.smegmatis_MC2_155 QEVAKDLGGLPVHEDSSIPAGSVRVVLGDDYTGPGSGLDG---NPALSSV
TH_3471|M.thermoresistible__bu REVADQLGDLPIVEDRTVAPGFVRVVLADDYTGPGSGLDGT--DPTVTTL
MUL_2613|M.ulcerans_Agy99 QQVAKELGGLPVVADTSIPSGSVRVVLSNDYSGPGSGLGG-----AMAPA
MMAR_1274|M.marinum_M QQVAKELGGLPVVADTSIPSGSVRVVLSNDYSGPGSGLGG-----AMAPA
Mb3295|M.bovis_AF2122/97 QQVAKELGGLPVVADASIAPGSVRVVLANDYSGPGSGLGGSDPNGVVSPA
Rv3267|M.tuberculosis_H37Rv QQVAKELGGLPVVADASIAPGSVRVVLANDYSGPGSGLGGSDPNGVVSPA
MLBr_00750|M.leprae_Br4923 QKVSKELGGLPIVVDGSIPAGSVLVILANDYTGPGSGLFG---NGSIASD
MAV_4232|M.avium_104 KEVSKELGGLPVVADSSLAPGAVRVVLANDYSGPGSGLSG---TESIMPA
MAB_3614|M.abscessus_ATCC_1997 KAVAEALG-LPVVEKQGIAEHTVRVVLSKDYQGPGSGRET-----TPAAS
: *: ** * : . :. * *:*. ** ***:*
Mflv_4737|M.gilvum_PYR-GCK DPSTSGVVS----DTGAAVPAPS--PIITAGSDDPKCVN
Mvan_1726|M.vanbaalenii_PYR-1 DPSTSGVVT----DTGATVPAPP--PILTAGSNDPECVN
MSMEG_1824|M.smegmatis_MC2_155 DPASSSASGYADGSSEDETPPPPPSPILTAGANDPQCVN
TH_3471|M.thermoresistible__bu QQSSATVG-----QTVEAAPPPP--QIITAGADDPKCVN
MUL_2613|M.ulcerans_Agy99 HASN--PGY-----S-DTAPPPS--PILTAGSDQPECIN
MMAR_1274|M.marinum_M HASN--PGY-----S-DTAPPPS--PILTAGSDQPECIN
Mb3295|M.bovis_AF2122/97 RAFN--LGS-----ADDTTPPPS--PILTAGSDAPECIN
Rv3267|M.tuberculosis_H37Rv RAFN--LGS-----ADDTTPPPS--PILTAGSDAPECIN
MLBr_00750|M.leprae_Br4923 YASNPGAS------ADPNIPVPS--PILTAGSDQPECIN
MAV_4232|M.avium_104 KVSTAGAVS-----TNDKAPAPS--PILTAGSDKPECIN
MAB_3614|M.abscessus_ATCC_1997 ETGS----------TEEDAPPPPPSPIFTA-ANGPRCVN
. : * *. *:** :: *.*:*