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VGESDDRATTDPTDPKGRAVPWRPKLLPVEDRRSIMDTLMVTLSGGALWRFAALMVLSSMVASIGLLQNS AAVVIGAMMIAPLMAPIMGIAACLIMGWGHRLLRGLALVAVSAMVAVGVGWITATLLPATGTGLASEVVA RSSPDIRDLLVAMGAGAVGALATVHKKISAALPGVAVAVAVVPPLGAAGVLLGRGQPQLARGAVILFSTN LVGIVVMAAVVFLLSGLVPLRKFRTHRRQIVASLGLAAVSVVAVAMILTPRFIALTGHARDLEIATQTLT DMLSPGSVLSHITATGSTVRADITSPTSPPPVQTVAASLSRALGHPVTVELSWIPVRDPEHSRPDTPQPP LNELGPVIRSWLGAQSLTLQGLSYESGTLVVSTAGPFPPKRAEELTSLIDSRFNYRIPVSLAWTRTSGPA KSDGTQAALDTARTTATTWAAKRPDVAVLSTNGTASAITITLIGQTQPEVDSLEADLQTALPQSTITIQW ISGGVLVVATPTPRTHAGSGTRARTDARKGVHLDALTETAGEDG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2273 | - | - | 100% (534) | hypothetical protein MUL_2273 |
| M. ulcerans Agy99 | MUL_2007 | mmpL7 | 8e-05 | 25.27% (182) | transmembrane transport protein MmpL7 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2632 | speE | 2e-07 | 28.25% (223) | spermidine synthase |
| M. gilvum PYR-GCK | Mflv_3772 | - | 4e-12 | 28.02% (232) | hypothetical protein Mflv_3772 |
| M. tuberculosis H37Rv | Rv2601 | speE | 2e-07 | 28.25% (223) | spermidine synthase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2864c | - | 7e-15 | 29.33% (225) | hypothetical protein MAB_2864c |
| M. marinum M | MMAR_3033 | - | 0.0 | 99.20% (503) | hypothetical protein MMAR_3033 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4626 | - | 5e-06 | 27.66% (188) | PUTATIVE ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_2627 | - | 4e-13 | 27.16% (232) | hypothetical protein Mvan_2627 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2273|M.ulcerans_Agy99 -------------------MGESDDRATTDPTDPKGRAVPWRPKLLPVED
MMAR_3033|M.marinum_M MTVELPPKPMLTEIPGRSAVGESDDRATTDPTDPKGRAVPWRPKLLPVED
Mflv_3772|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2627|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2864c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2632|M.bovis_AF2122/97 ---------------------MTSTRQAGEATEASVRWRAVLLAAVAACA
Rv2601|M.tuberculosis_H37Rv ---------------------MTSTRQAGEATEASVRWRAVLLAAVAACA
TH_4626|M.thermoresistible__bu -----------------MIRTLLRLVPAEKRGAVAGYAVLTLLSVLLRAV
MUL_2273|M.ulcerans_Agy99 RRSIMDTLMVTLSGGALWRFAALMVLSSMVASIGLLQNSAAVVIGAMMIA
MMAR_3033|M.marinum_M RRSIMDTLMVTLSGGALWRFAALMFLSSMVASIGLLQNSAAVVIGAMMIA
Mflv_3772|M.gilvum_PYR-GCK ------MLHLRVVVPEDMRDDVLDVLRSQVGVAHVLLHPGAAVD------
Mvan_2627|M.vanbaalenii_PYR-1 ------MLHLRVIAPEDLRDDVLRVLQRHVGVAHLVIHPGAALD------
MAB_2864c|M.abscessus_ATCC_199 ------MLHLRVIAPAEVSDQVVEFLSTTTGVTHIVRVPQAAIS------
Mb2632|M.bovis_AF2122/97 ACGLVYELALLTLAASLNGGGIVATSLIVAGYIAALGAGALLIKPLLAHA
Rv2601|M.tuberculosis_H37Rv ACGLVYELALLTLAASLNGGGIVATSLIVAGYIAALGAGALLIKPLLAHA
TH_4626|M.thermoresistible__bu GAVLLIPLLAALFSDTPSDAWLWLGWLTAVTLAGWVTDTNTARLGFDLGF
* . :
MUL_2273|M.ulcerans_Agy99 PLMAPIMGIAACLIMGWGHRLLRGLALVAVSAMVAVGVGWITATLLPATG
MMAR_3033|M.marinum_M PLMAPIMGIAACLIMGWGHRLLRGLALVAVSAMVAVGVGWITATLLPATG
Mflv_3772|M.gilvum_PYR-GCK -----------------------------------------------PAG
Mvan_2627|M.vanbaalenii_PYR-1 -----------------------------------------------PEG
MAB_2864c|M.abscessus_ATCC_199 -----------------------------------------------PAG
Mb2632|M.bovis_AF2122/97 AIAFIAVEAVLGIIGG-------------------------------LSA
Rv2601|M.tuberculosis_H37Rv AIAFIAVEAVLGIIGG-------------------------------LSA
TH_4626|M.thermoresistible__bu AVLSRTQHDMADRLPN------------------------VAMSWFTPDN
MUL_2273|M.ulcerans_Agy99 TGLASEVVARSSPDIRDLLVAMGAGAVG--------------ALATVHKK
MMAR_3033|M.marinum_M TGLPSEVVARSSPDIRDLLVAMGAGAVG--------------ALATVHKK
Mflv_3772|M.gilvum_PYR-GCK DVIAADLARECANDVIKNLKDLDAQHRG--------------AIT-----
Mvan_2627|M.vanbaalenii_PYR-1 DEIAADVARESANDVVKQLKDLDVQHRG--------------AIT-----
MAB_2864c|M.abscessus_ATCC_199 DLITADVARETANDVLDGLKSIDIDKRG--------------SIT-----
Mb2632|M.bovis_AF2122/97 AALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVP-----LLMTLLQRG
Rv2601|M.tuberculosis_H37Rv AALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVP-----LLMTLLQRG
TH_4626|M.thermoresistible__bu TATARQAIAATGPELAGLVVNLLTPLIGAALLPAAIGVALLFVSVPLGLA
: : : * .
MUL_2273|M.ulcerans_Agy99 ISAALPGVAVAVAVVPPLGAAGVLLGRGQPQLARGAVILFST--------
MMAR_3033|M.marinum_M ISAALPGVAVAVAVVPPLGAAGVLLGRGQPQLARGAVILFST--------
Mflv_3772|M.gilvum_PYR-GCK -----LTVLDTVLSTRAHRAEEEAVGDPADAVVWDELIGRTR--------
Mvan_2627|M.vanbaalenii_PYR-1 -----LTALDTVLSTRAHRAEDEAEGDPADALVWDELITRTR--------
MAB_2864c|M.abscessus_ATCC_199 -----AEVLDTVISQTAYEAEDDAEGDPADAVIWDELIGRTR--------
Mb2632|M.bovis_AF2122/97 RVAGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIR--------
Rv2601|M.tuberculosis_H37Rv RVAGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIR--------
TH_4626|M.thermoresistible__bu ALAGVAVLFGALALSGRLSRAADKVAGETNSAFTERIIEFARTQQALRAA
:: . :
MUL_2273|M.ulcerans_Agy99 ----------------------NLVGIVVMAAVVFLLSGLVPLRKFRTHR
MMAR_3033|M.marinum_M ----------------------NLVGIVVMAAVVFLLSGLVPLRKFRTHR
Mflv_3772|M.gilvum_PYR-GCK ----------------------EEATLSVTFVLFLTLACLLTAIGVVTDS
Mvan_2627|M.vanbaalenii_PYR-1 ----------------------EESTLSVTFMTFLTLACLLAAIGAVTDS
MAB_2864c|M.abscessus_ATCC_199 ----------------------EESTLNLTFLAFLCLACLIAAVGVVTDS
Mb2632|M.bovis_AF2122/97 ----------------------GAAVTGIVNLAAAGVVSIFLLRHVVSGR
Rv2601|M.tuberculosis_H37Rv ----------------------GAAVTGIVNLAAAGVVSIFLLRHVVSGR
TH_4626|M.thermoresistible__bu RRVEPARSQVGSALAAQHGAGLRLLTMQIPGQVLFSLAGQVALIGFAGMA
: : .
MUL_2273|M.ulcerans_Agy99 RQIVASLGLAAVSVVAVAMILT-----------PRFIALTGHARDLEIAT
MMAR_3033|M.marinum_M RQIVASLGLAAVSAVAVAMILT-----------PRFIALTGHARDLEIAT
Mflv_3772|M.gilvum_PYR-GCK -----------TVTVVGAMVLG-----------PEFGPLAALSVALVQRR
Mvan_2627|M.vanbaalenii_PYR-1 -----------MVTVVGAMVLG-----------PEFGPLAALSVALVQRR
MAB_2864c|M.abscessus_ATCC_199 -----------PVTIVGAMVVG-----------PEFGPLAALAVSIVRRK
Mb2632|M.bovis_AF2122/97 QLVTALCALAAALGLIATLLVHSHDIETTGRQQLYADPIIAYRHSAYQEI
Rv2601|M.tuberculosis_H37Rv QLVTALCALAAALGLIATLLVHSHDIETTGRQQLYADPIIAYRHSAYQEI
TH_4626|M.thermoresistible__bu VWLTVRGQLGVPEAIALIVVLVR--------YLEPFAAIADLAPALETTR
: ::: .:
MUL_2273|M.ulcerans_Agy99 QTLT-------------------DMLSPGSVLSHITATGSTVRADITSPT
MMAR_3033|M.marinum_M QTLT-------------------DMLSPGSVLSHITATGSTVRADITSPT
Mflv_3772|M.gilvum_PYR-GCK MALA-------------------RRAAVALVVGFPIAMA-----------
Mvan_2627|M.vanbaalenii_PYR-1 GDLA-------------------RRATIALLIGFPVAMG-----------
MAB_2864c|M.abscessus_ATCC_199 WSLA-------------------RRSLLALLVGFPVAMG-----------
Mb2632|M.bovis_AF2122/97 VVTR-------------------RGDDLRLYLDGGLQFCTRDEYRYTESL
Rv2601|M.tuberculosis_H37Rv VVTR-------------------RGDDLRLYLDGGLQFCTRDEYRYTESL
TH_4626|M.thermoresistible__bu ATLNRIQAVLDAPTLPAGRRRLDRTGAAPSIEFDDVRFSYGDEVVLDGVS
MUL_2273|M.ulcerans_Agy99 SPPPVQTVAASLSRALGHPVTVELSWIPVRDPEHSRPDTPQPPLNELGPV
MMAR_3033|M.marinum_M SPPPVQTVAASLSRALGHPVTVELSWIPVRDPEHSRPDTPQPPLNELGPV
Mflv_3772|M.gilvum_PYR-GCK ----ITAIATWAAESLG--------WITLDSVAH---------VEEVDFI
Mvan_2627|M.vanbaalenii_PYR-1 ----ITALLTLAGRAVG--------WLSFDTIGD---------IHDVDFI
MAB_2864c|M.abscessus_ATCC_199 ----VTAVGALAAEAAG--------WVTLKSVRE---------LQQVDFV
Mb2632|M.bovis_AF2122/97 VYPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELART
Rv2601|M.tuberculosis_H37Rv VYPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELART
TH_4626|M.thermoresistible__bu FTLRPGNTTAIVGPSGSGKTTILSLIAGLQQPASGRVLLDGVDVTTLDPE
. : :
MUL_2273|M.ulcerans_Agy99 IRSWLGAQSLTLQGLSYESGTLVVSTAGPFPPKRAEELTSLIDSRFNYRI
MMAR_3033|M.marinum_M IRSWLGAQSLTLQGLSYESGTLVVSTAGPFPPKRAEELTSLIDSRFNYRI
Mflv_3772|M.gilvum_PYR-GCK FR--VGPVSFMVALLAGAAGMLSLVSA------RSAGLVGVFIS------
Mvan_2627|M.vanbaalenii_PYR-1 FQ--VGPVSFVVALLAGAAGMLSLMSS------KSAALVGVFIS------
MAB_2864c|M.abscessus_ATCC_199 FQ--VGPFSLVVALLAGAAGMLSLMSA------KSAALVGVFIS------
Mb2632|M.bovis_AF2122/97 TLRDVNAGSLDNPRVHVVIDDAMSWLRGAAVPPAGFDAVIVDLRDPDTPV
Rv2601|M.tuberculosis_H37Rv TLRDVNAGSLDNPRVHVVIDDAMSWLRGAAVPPAGFDAVIVDLRDPDTPV
TH_4626|M.thermoresistible__bu ARRAAVSVVFQHPYLFDGTLRDNVLVGDPEADPDDVTAAMRLARVDELLD
. : : .
MUL_2273|M.ulcerans_Agy99 PVSLAWTRTSGPAKSDGTQAALDTARTTATTWAAKRPDVAVLSTNGTASA
MMAR_3033|M.marinum_M PVSLAWTRTSGPAKSDGTQAALDTARTTATAWAAKRPDVAVLSTNGTASA
Mflv_3772|M.gilvum_PYR-GCK -------------VYTVTAAGFAVVAATVGAWDVAAKSALQLVVNLVGIV
Mvan_2627|M.vanbaalenii_PYR-1 -------------VTTVPAAGFTAVAGILGHWDVAAQSAAQLAVNLVGVV
MAB_2864c|M.abscessus_ATCC_199 -------------VTTVPAAGFAVVAATVGEWDIAGLSALQLAVNLFGIV
Mb2632|M.bovis_AF2122/97 LGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAGYA
Rv2601|M.tuberculosis_H37Rv LGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAGYA
TH_4626|M.thermoresistible__bu RLPDGDATVVGEGGTALSGGERQRVSIARALLKPAPVLLVDEATSALDNA
. . . .
MUL_2273|M.ulcerans_Agy99 ITITLIGQTQP------EVDSLEADLQTALPQSTITIQWISGGVLVVATP
MMAR_3033|M.marinum_M ITITLIGQTQP------EVDSLEADLQTALPQSTITIQWISGGVLVVATP
Mflv_3772|M.gilvum_PYR-GCK LAGVLVLVLRP------RGRLVARTARK----------------------
Mvan_2627|M.vanbaalenii_PYR-1 LAGVLVLVLRP------RGNVIPRSAQT----------------------
MAB_2864c|M.abscessus_ATCC_199 LAGVLVLWVRP------RGYR-----------------------------
Mb2632|M.bovis_AF2122/97 VTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAATV
Rv2601|M.tuberculosis_H37Rv VTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAATV
TH_4626|M.thermoresistible__bu NEAAVVDALTADP---RPRTRVIVAHRLASIRHADRVLFVEAGRVVEDGA
:
MUL_2273|M.ulcerans_Agy99 TPRTHAGSGTRARTDARKGVHLDALTETAGEDG
MMAR_3033|M.marinum_M TPEPTPAPAPEPEPTPAK---VSASTR------
Mflv_3772|M.gilvum_PYR-GCK ---------------------------------
Mvan_2627|M.vanbaalenii_PYR-1 ---------------------------------
MAB_2864c|M.abscessus_ATCC_199 ---------------------------------
Mb2632|M.bovis_AF2122/97 FSGDIRPRTLDPSTLDNPHIVEDMRHGWD----
Rv2601|M.tuberculosis_H37Rv FSGDIRPRTLDPSTLDNPHIVEDMRHGWD----
TH_4626|M.thermoresistible__bu IDELLAAGGRFAQFWAQQQAASEWAIGSTAR--