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VPNQRRGPRRRPLDPARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAALATELTYGACRARGLLD AIIGAAAGRSPEAIDPFLLDLLRLGAYQLLRTRVDAHAAVSTTVEQAGIEFDSARAGFVNAVLRTIADRD EQSWVQELAPDPRRDPVGHAAFVHTHPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAA ALADEVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAPVEGDSGRWLDLCAGPG GKTALLAALGVATGARVTAVEPSSHRADLVADNTGGLPVDLVRGDGRYTDLEPVFDRVLVDAPCTGLGAL RRRPEARWRRQPSDVPTLVKLQRELLAAAINLTRPGGVVFYATCSPHLAETVGVVADALRRHPVDALDTR ALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1803 | fmu | - | 100% (457) | Fmu protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1442 | fmu | 0.0 | 84.89% (450) | Fmu protein (SUN protein) |
| M. gilvum PYR-GCK | Mflv_3729 | - | 0.0 | 78.19% (454) | Fmu (Sun) domain-containing protein |
| M. tuberculosis H37Rv | Rv1407 | fmu | 0.0 | 84.89% (450) | Fmu protein (SUN protein) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2810c | - | 1e-177 | 71.05% (449) | Fmu protein (SUN protein) |
| M. marinum M | MMAR_2216 | fmu | 0.0 | 99.12% (457) | Fmu protein |
| M. avium 104 | MAV_3371 | - | 0.0 | 84.25% (438) | Fmu protein |
| M. smegmatis MC2 155 | MSMEG_3065 | sun | 0.0 | 76.65% (454) | ribosomal RNA small subunit methyltransferase B |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2688 | - | 0.0 | 78.97% (447) | Fmu (Sun) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3729|M.gilvum_PYR-GCK ----------------------MTRPDKKRPPR------------RKRLD
Mvan_2688|M.vanbaalenii_PYR-1 -------------------------------MK------------RKRLD
MSMEG_3065|M.smegmatis_MC2_155 --------------------MKPNHPPRKRPPR------------RKPLD
MUL_1803|M.ulcerans_Agy99 ------------------------MPNQRRGPR------------RRPLD
MMAR_2216|M.marinum_M MSPGQDKRQRNRPDRKPRRSEGTGVPNQRRGPR------------RRPLD
Mb1442|M.bovis_AF2122/97 ------------------------MTPRSRGPR------------RRPLD
Rv1407|M.tuberculosis_H37Rv ------------------------MTPRSRGPR------------RRPLD
MAV_3371|M.avium_104 --------------------------------------------------
MAB_2810c|M.abscessus_ATCC_199 ---------------------MSTRPPRRRSNQDSRRSAGPAERARRKLD
Mflv_3729|M.gilvum_PYR-GCK PARQAAFDVLRAVSERDSYANLALPALLRDRRITGRDAAFATELTYGTCR
Mvan_2688|M.vanbaalenii_PYR-1 PARQAAFDVLRAVSERDAYANLALPALLRDRGITGRDAAFATELTYGTCR
MSMEG_3065|M.smegmatis_MC2_155 PARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACR
MUL_1803|M.ulcerans_Agy99 PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAALATELTYGACR
MMAR_2216|M.marinum_M PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAAFATELTYGACR
Mb1442|M.bovis_AF2122/97 PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
Rv1407|M.tuberculosis_H37Rv PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
MAV_3371|M.avium_104 --------MLRAVSERDAYANLALPALLRERGITGRDAAFATELTYGTCR
MAB_2810c|M.abscessus_ATCC_199 PPRQAALDVLRAVSRQDAYANLALPALLRERGITGRDAAFATELTYGTCR
***** :::****.***:* :* * *****:*******:**
Mflv_3729|M.gilvum_PYR-GCK AKGLLDAVIAAAAGRPVDHIDPILLDLLRLGAYQILRTRVDDHAAVSTTV
Mvan_2688|M.vanbaalenii_PYR-1 TRGLLDAVIAAAAGRPVDKIDPVLLDLLRLGSYQLLRTRVDDHAAVSTTV
MSMEG_3065|M.smegmatis_MC2_155 SLGLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTV
MUL_1803|M.ulcerans_Agy99 ARGLLDAIIGAAAGRSPEAIDPFLLDLLRLGAYQLLRTRVDAHAAVSTTV
MMAR_2216|M.marinum_M ARGLLDAIIGAAAGRSPEAIDPVLLDLLRLGAYQLLRTRVDAHAAVSTTV
Mb1442|M.bovis_AF2122/97 ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
Rv1407|M.tuberculosis_H37Rv ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
MAV_3371|M.avium_104 TRGLLDAVIGAAAGRPPEAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
MAB_2810c|M.abscessus_ATCC_199 ARGLLDAVIEAAAGRTIDQVDEGLRDPLRLGAYQLLRTRVEPHAALSTTV
: *****:* ** *. : :* * * ****:**:*****: ***:****
Mflv_3729|M.gilvum_PYR-GCK EQAGLEFDTARAGFVNGVLRTIARRDEADWVAELAPPAATDPVGHLAFVH
Mvan_2688|M.vanbaalenii_PYR-1 DQAGIEFDSSRAGFVNGVLRTIARRDEASWVEELAPSATGDPIGHLAFVH
MSMEG_3065|M.smegmatis_MC2_155 EQAGIEFDSARAGFVNGVLRTISGRDEQAWIAELAPSAETDPVGHTAFVH
MUL_1803|M.ulcerans_Agy99 EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
MMAR_2216|M.marinum_M EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
Mb1442|M.bovis_AF2122/97 EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
Rv1407|M.tuberculosis_H37Rv EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
MAV_3371|M.avium_104 EQAAIEFDSARAGFVNGVLRRIAGRDERSWVQELAPDPARDPIGHAAFVH
MAB_2810c|M.abscessus_ATCC_199 DAVAVEFDQGRAGFVNAVLRTISRRDEADWVEELAP-PESDRIGRLAFAT
: ..:*** .******.*** *: *** *: **** . * :*: **.
Mflv_3729|M.gilvum_PYR-GCK AHPRWIGQAFADALGARAGELGALLASDDSRPEVHLAARPGMLTAAELAE
Mvan_2688|M.vanbaalenii_PYR-1 AHPRWVAQAFADALGARAGELGALLASDDSRPEVHLVARPGALTAAELAE
MSMEG_3065|M.smegmatis_MC2_155 AHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTAITAEELAE
MUL_1803|M.ulcerans_Agy99 THPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
MMAR_2216|M.marinum_M AHPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
Mb1442|M.bovis_AF2122/97 AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
Rv1407|M.tuberculosis_H37Rv AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
MAV_3371|M.avium_104 AHPRWIAQAFADALGAAAAELDAVLASDDERPQVHLAARPGALTAAELAD
MAB_2810c|M.abscessus_ATCC_199 AHPRWIAQSFSDALGPAGSELAQVLASDDERPLVHLAARPGRIDAEALAE
:****:.*:*:****. .** :***** ** ***.*** : * **
Mflv_3729|M.gilvum_PYR-GCK QTGGTVGRYSPYAVYLGDGDPGGVAAVRESRALVQDEGSQLVARALTLAP
Mvan_2688|M.vanbaalenii_PYR-1 QVGGGVGRYSPYAVYLGEGDPGQLAAVREGTALVQDEGSQLVARALTLAP
MSMEG_3065|M.smegmatis_MC2_155 QAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAE
MUL_1803|M.ulcerans_Agy99 EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
MMAR_2216|M.marinum_M EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
Mb1442|M.bovis_AF2122/97 AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
Rv1407|M.tuberculosis_H37Rv AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
MAV_3371|M.avium_104 AVGGTVGRHSPFAVYLAGGDPGRLAPVRDGLALVQDEGSQLVARALTLAP
MAB_2810c|M.abscessus_ATCC_199 AVGGTVGRYSPFAVYLPGGDPGRLEPVRDGLAQVQDEGSQLIARATALAP
. * ***:**:**** **** : .**:. * ********:*** :**
Mflv_3729|M.gilvum_PYR-GCK VDGPDGGRWLDLCAGPGGKTALLAALGQPSGA----TVTAVEPAPRRAEL
Mvan_2688|M.vanbaalenii_PYR-1 LVGPDGGRWLDLCAGPGGKTALLAALGAPEGV----TVTAVEPAPRRADL
MSMEG_3065|M.smegmatis_MC2_155 VDGTDEGRWLDLCSGPGGKTALLASIGAASGA----RVTAVEPAERRADL
MUL_1803|M.ulcerans_Agy99 VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
MMAR_2216|M.marinum_M VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
Mb1442|M.bovis_AF2122/97 VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
Rv1407|M.tuberculosis_H37Rv VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
MAV_3371|M.avium_104 VDG-DCGRWLDLCAGPGGKTALLASLGAQRFSGPQFRVTAVEPAPRRADL
MAB_2810c|M.abscessus_ATCC_199 LQG-ADEQWLDLCAGPGGKTALLGALAAQRGA----HVTAVEVAPHRAEL
: * :*****:*********..:. ***** : :**:*
Mflv_3729|M.gilvum_PYR-GCK VEQNTAGLPVDVVRVDGRESGLTPG-FDRVLVDAPCTGLGALRRRPEARW
Mvan_2688|M.vanbaalenii_PYR-1 VEQNTAGLPVEVVRVDGREPGLAPG-FDRVLVDAPCTGLGALRRRPEARW
MSMEG_3065|M.smegmatis_MC2_155 VEENTRGLGVEVHRVDGRESGLQPG-FDRVLVDAPCTGLGALRRRPESRW
MUL_1803|M.ulcerans_Agy99 VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
MMAR_2216|M.marinum_M VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
Mb1442|M.bovis_AF2122/97 VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
Rv1407|M.tuberculosis_H37Rv VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
MAV_3371|M.avium_104 VVENTRGLPVEVLRVDGRHTGLQPA-FDRVLVDAPCTGLGALRRRPEARW
MAB_2810c|M.abscessus_ATCC_199 VANATKSLPVTVVTADGRDSDLAAASFDRVLVDAPCTGLGALRRRPEARW
* : * .* * : *** ..* . *********************:**
Mflv_3729|M.gilvum_PYR-GCK RRQPGDVPALAKLQRELLAAAIRLTRPGGVVLYATCSPHLAETAGVVADA
Mvan_2688|M.vanbaalenii_PYR-1 RRQPGDVPPLAKLQRELLASAIRLTRPGGVVLYATCSPHLAETAGVVADA
MSMEG_3065|M.smegmatis_MC2_155 RRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADA
MUL_1803|M.ulcerans_Agy99 RRQPSDVPTLVKLQRELLAAAINLTRPGGVVFYATCSPHLAETVGVVADA
MMAR_2216|M.marinum_M RRQPSDVPTLVKLQRELLAAAINLTRPGGVVLYATCSPHLAETVGVVADA
Mb1442|M.bovis_AF2122/97 RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
Rv1407|M.tuberculosis_H37Rv RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
MAV_3371|M.avium_104 RRQPGDVPTLTKLQRELLGAAIALTRPGGVVLYATCSPHLAETVGVVADA
MAB_2810c|M.abscessus_ATCC_199 RRQPGDIPELVKLQRELLASAIQLTRPGGVIVYSTCSPHLAETVGVVSDA
****.*:. *.:******.:** *******:.*:*********.*.*:**
Mflv_3729|M.gilvum_PYR-GCK LRRQPVTALDTGELFSPATD-TGDGPSVQLWPHRHGTDAMFAAALRVDAA
Mvan_2688|M.vanbaalenii_PYR-1 LRRHPVTALDTRELFEPATD-TGDGTSVQLWPHRHGTDAMFAAALRVN--
MSMEG_3065|M.smegmatis_MC2_155 IRRHPVTAMDTRPLFAPVDD-LGAGPHVQLWPHRHGTDAMFAAALRVDPD
MUL_1803|M.ulcerans_Agy99 LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
MMAR_2216|M.marinum_M LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
Mb1442|M.bovis_AF2122/97 LRRHPVHALDTRPLFEPVLAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
Rv1407|M.tuberculosis_H37Rv LRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
MAV_3371|M.avium_104 LRRHPVSALDARPLFEPVAD-LGDGPHVQLWPHRHGTDAMFAAALRREAG
MAB_2810c|M.abscessus_ATCC_199 VRRYAVSAEDARAVFPGVAG-LGDADAVQLWPHRHGTDAMFTALLRKHA-
:** .* * *: :* * . **************:* **
Mflv_3729|M.gilvum_PYR-GCK AR
Mvan_2688|M.vanbaalenii_PYR-1 --
MSMEG_3065|M.smegmatis_MC2_155 VR
MUL_1803|M.ulcerans_Agy99 --
MMAR_2216|M.marinum_M --
Mb1442|M.bovis_AF2122/97 --
Rv1407|M.tuberculosis_H37Rv --
MAV_3371|M.avium_104 --
MAB_2810c|M.abscessus_ATCC_199 --