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STRPPRRRSNQDSRRSAGPAERARRKLDPPRQAALDVLRAVSRQDAYANLALPALLRERGITGRDAAFAT ELTYGTCRARGLLDAVIEAAAGRTIDQVDEGLRDPLRLGAYQLLRTRVEPHAALSTTVDAVAVEFDQGRA GFVNAVLRTISRRDEADWVEELAPPESDRIGRLAFATAHPRWIAQSFSDALGPAGSELAQVLASDDERPL VHLAARPGRIDAEALAEAVGGTVGRYSPFAVYLPGGDPGRLEPVRDGLAQVQDEGSQLIARATALAPLQG ADEQWLDLCAGPGGKTALLGALAAQRGAHVTAVEVAPHRAELVANATKSLPVTVVTADGRDSDLAAASFD RVLVDAPCTGLGALRRRPEARWRRQPGDIPELVKLQRELLASAIQLTRPGGVIVYSTCSPHLAETVGVVS DAVRRYAVSAEDARAVFPGVAGLGDADAVQLWPHRHGTDAMFTALLRKHA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2810c | - | - | 100% (471) | Fmu protein (SUN protein) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1442 | fmu | 1e-174 | 69.74% (456) | Fmu protein (SUN protein) |
| M. gilvum PYR-GCK | Mflv_3729 | - | 1e-175 | 70.16% (449) | Fmu (Sun) domain-containing protein |
| M. tuberculosis H37Rv | Rv1407 | fmu | 1e-174 | 69.74% (456) | Fmu protein (SUN protein) |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2216 | fmu | 1e-180 | 69.56% (473) | Fmu protein |
| M. avium 104 | MAV_3371 | - | 1e-176 | 72.89% (439) | Fmu protein |
| M. smegmatis MC2 155 | MSMEG_3065 | sun | 1e-173 | 67.60% (466) | ribosomal RNA small subunit methyltransferase B |
| M. thermoresistible (build 8) | TH_2937 | - | 3e-08 | 33.54% (158) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_1803 | fmu | 1e-177 | 71.05% (449) | Fmu protein |
| M. vanbaalenii PYR-1 | Mvan_2688 | - | 1e-178 | 71.75% (446) | Fmu (Sun) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1442|M.bovis_AF2122/97 ------------------------MTPRSRGPR------------RRPLD
Rv1407|M.tuberculosis_H37Rv ------------------------MTPRSRGPR------------RRPLD
MMAR_2216|M.marinum_M MSPGQDKRQRNRPDRKPRRSEGTGVPNQRRGPR------------RRPLD
MUL_1803|M.ulcerans_Agy99 ------------------------MPNQRRGPR------------RRPLD
MAV_3371|M.avium_104 --------------------------------------------------
Mflv_3729|M.gilvum_PYR-GCK ----------------------MTRPDKKRPPR------------RKRLD
Mvan_2688|M.vanbaalenii_PYR-1 -------------------------------MK------------RKRLD
MSMEG_3065|M.smegmatis_MC2_155 --------------------MKPNHPPRKRPPR------------RKPLD
MAB_2810c|M.abscessus_ATCC_199 ---------------------MSTRPPRRRSNQDSRRSAGPAERARRKLD
TH_2937|M.thermoresistible__bu --------------------------------------------------
Mb1442|M.bovis_AF2122/97 PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
Rv1407|M.tuberculosis_H37Rv PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
MMAR_2216|M.marinum_M PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAAFATELTYGACR
MUL_1803|M.ulcerans_Agy99 PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAALATELTYGACR
MAV_3371|M.avium_104 --------MLRAVSERDAYANLALPALLRERGITGRDAAFATELTYGTCR
Mflv_3729|M.gilvum_PYR-GCK PARQAAFDVLRAVSERDSYANLALPALLRDRRITGRDAAFATELTYGTCR
Mvan_2688|M.vanbaalenii_PYR-1 PARQAAFDVLRAVSERDAYANLALPALLRDRGITGRDAAFATELTYGTCR
MSMEG_3065|M.smegmatis_MC2_155 PARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACR
MAB_2810c|M.abscessus_ATCC_199 PPRQAALDVLRAVSRQDAYANLALPALLRERGITGRDAAFATELTYGTCR
TH_2937|M.thermoresistible__bu ---------------------------VTTNWAAGRYEAVGERIAP----
: . ** *.. .::
Mb1442|M.bovis_AF2122/97 ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
Rv1407|M.tuberculosis_H37Rv ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
MMAR_2216|M.marinum_M ARGLLDAIIGAAAGRSPEAIDPVLLDLLRLGAYQLLRTRVDAHAAVSTTV
MUL_1803|M.ulcerans_Agy99 ARGLLDAIIGAAAGRSPEAIDPFLLDLLRLGAYQLLRTRVDAHAAVSTTV
MAV_3371|M.avium_104 TRGLLDAVIGAAAGRPPEAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
Mflv_3729|M.gilvum_PYR-GCK AKGLLDAVIAAAAGRPVDHIDPILLDLLRLGAYQILRTRVDDHAAVSTTV
Mvan_2688|M.vanbaalenii_PYR-1 TRGLLDAVIAAAAGRPVDKIDPVLLDLLRLGSYQLLRTRVDDHAAVSTTV
MSMEG_3065|M.smegmatis_MC2_155 SLGLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTV
MAB_2810c|M.abscessus_ATCC_199 ARGLLDAVIEAAAGRTIDQVDEGLRDPLRLGAYQLLRTRVEPHAALSTTV
TH_2937|M.thermoresistible__bu ---IADEVLDAAARRTP-LRGATLVDLACGTGSAALSATARGAAVTGVDI
: * :: ** *. . * * * : . *. .. :
Mb1442|M.bovis_AF2122/97 EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
Rv1407|M.tuberculosis_H37Rv EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
MMAR_2216|M.marinum_M EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
MUL_1803|M.ulcerans_Agy99 EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
MAV_3371|M.avium_104 EQAAIEFDSARAGFVNGVLRRIAGRDERSWVQELAPDPARDPIGHAAFVH
Mflv_3729|M.gilvum_PYR-GCK EQAGLEFDTARAGFVNGVLRTIARRDEADWVAELAPPAATDPVGHLAFVH
Mvan_2688|M.vanbaalenii_PYR-1 DQAGIEFDSSRAGFVNGVLRTIARRDEASWVEELAPSATGDPIGHLAFVH
MSMEG_3065|M.smegmatis_MC2_155 EQAGIEFDSARAGFVNGVLRTISGRDEQAWIAELAPSAETDPVGHTAFVH
MAB_2810c|M.abscessus_ATCC_199 DAVAVEFDQGRAGFVNAVLRTISRRDEADWVEELAP-PESDRIGRLAFAT
TH_2937|M.thermoresistible__bu TSELIALAAGKP-----------GGSTVTWVTADAADTGLK---------
: : .:. . *: *. . .
Mb1442|M.bovis_AF2122/97 AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
Rv1407|M.tuberculosis_H37Rv AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
MMAR_2216|M.marinum_M AHPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
MUL_1803|M.ulcerans_Agy99 THPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
MAV_3371|M.avium_104 AHPRWIAQAFADALGAAAAELDAVLASDDERPQVHLAARPGALTAAELAD
Mflv_3729|M.gilvum_PYR-GCK AHPRWIGQAFADALGARAGELGALLASDDSRPEVHLAARPGMLTAAELAE
Mvan_2688|M.vanbaalenii_PYR-1 AHPRWVAQAFADALGARAGELGALLASDDSRPEVHLVARPGALTAAELAE
MSMEG_3065|M.smegmatis_MC2_155 AHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTAITAEELAE
MAB_2810c|M.abscessus_ATCC_199 AHPRWIAQSFSDALGPAGSELAQVLASDDERPLVHLAARPGRIDAEALAE
TH_2937|M.thermoresistible__bu ----------TASFDVAVSNMGIIFVPPDRQ-------------VAELAR
: ::. .:: ::.. * : . **
Mb1442|M.bovis_AF2122/97 AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
Rv1407|M.tuberculosis_H37Rv AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
MMAR_2216|M.marinum_M EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
MUL_1803|M.ulcerans_Agy99 EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
MAV_3371|M.avium_104 AVGGTVGRHSPFAVYLAGGDPGRLAPVRDGLALVQDEGSQLVARALTLAP
Mflv_3729|M.gilvum_PYR-GCK QTGGTVGRYSPYAVYLGDGDPGGVAAVRESRALVQDEGSQLVARALTLAP
Mvan_2688|M.vanbaalenii_PYR-1 QVGGGVGRYSPYAVYLGEGDPGQLAAVREGTALVQDEGSQLVARALTLAP
MSMEG_3065|M.smegmatis_MC2_155 QAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAE
MAB_2810c|M.abscessus_ATCC_199 AVGGTVGRYSPFAVYLPGGDPGRLEPVRDGLAQVQDEGSQLIARATALAP
TH_2937|M.thermoresistible__bu LLK-------------PGGVLSFSAWIRTDENPFSDPVAEVLG-----PP
* . :* . ..* ::::. .
Mb1442|M.bovis_AF2122/97 VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
Rv1407|M.tuberculosis_H37Rv VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
MMAR_2216|M.marinum_M VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
MUL_1803|M.ulcerans_Agy99 VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
MAV_3371|M.avium_104 VDG-DCGRWLDLCAGPGGKTALLASLGAQRFSGPQFRVTAVEPAPRRADL
Mflv_3729|M.gilvum_PYR-GCK VDGPDGGRWLDLCAGPGGKTALLAALGQPSGA----TVTAVEPAPRRAEL
Mvan_2688|M.vanbaalenii_PYR-1 LVGPDGGRWLDLCAGPGGKTALLAALGAPEGV----TVTAVEPAPRRADL
MSMEG_3065|M.smegmatis_MC2_155 VDGTDEGRWLDLCSGPGGKTALLASIGAASGA----RVTAVEPAERRADL
MAB_2810c|M.abscessus_ATCC_199 LQG-ADEQWLDLCAGPGGKTALLGALAAQRGA----HVTAVEVAPHRAEL
TH_2937|M.thermoresistible__bu PAGFSPDQWGDAETLTERLTPHFDAIDLIRGL------------------
* :* * : . *. : .:
Mb1442|M.bovis_AF2122/97 VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
Rv1407|M.tuberculosis_H37Rv VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
MMAR_2216|M.marinum_M VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
MUL_1803|M.ulcerans_Agy99 VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
MAV_3371|M.avium_104 VVENTRGLPVEVLRVDGRHTGLQPA-FDRVLVDAPCTGLGALRRRPEARW
Mflv_3729|M.gilvum_PYR-GCK VEQNTAGLPVDVVRVDGRESGLTPG-FDRVLVDAPCTGLGALRRRPEARW
Mvan_2688|M.vanbaalenii_PYR-1 VEQNTAGLPVEVVRVDGREPGLAPG-FDRVLVDAPCTGLGALRRRPEARW
MSMEG_3065|M.smegmatis_MC2_155 VEENTRGLGVEVHRVDGRESGLQPG-FDRVLVDAPCTGLGALRRRPESRW
MAB_2810c|M.abscessus_ATCC_199 VANATKSLPVTVVTADGRDSDLAAASFDRVLVDAPCTGLGALRRRPEARW
TH_2937|M.thermoresistible__bu ---------------------------HPWEFDSPATALHFLRTES----
. .*:*.*.* ** ..
Mb1442|M.bovis_AF2122/97 RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
Rv1407|M.tuberculosis_H37Rv RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
MMAR_2216|M.marinum_M RRQPSDVPTLVKLQRELLAAAINLTRPGGVVLYATCSPHLAETVGVVADA
MUL_1803|M.ulcerans_Agy99 RRQPSDVPTLVKLQRELLAAAINLTRPGGVVFYATCSPHLAETVGVVADA
MAV_3371|M.avium_104 RRQPGDVPTLTKLQRELLGAAIALTRPGGVVLYATCSPHLAETVGVVADA
Mflv_3729|M.gilvum_PYR-GCK RRQPGDVPALAKLQRELLAAAIRLTRPGGVVLYATCSPHLAETAGVVADA
Mvan_2688|M.vanbaalenii_PYR-1 RRQPGDVPPLAKLQRELLASAIRLTRPGGVVLYATCSPHLAETAGVVADA
MSMEG_3065|M.smegmatis_MC2_155 RRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADA
MAB_2810c|M.abscessus_ATCC_199 RRQPGDIPELVKLQRELLASAIQLTRPGGVIVYSTCSPHLAETVGVVSDA
TH_2937|M.thermoresistible__bu --------------------------PVHVEIFRRAGPARRERLAAAFRS
* * .: ..* * ... :
Mb1442|M.bovis_AF2122/97 LRRHPVHALDTRPLFEPVLAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
Rv1407|M.tuberculosis_H37Rv LRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
MMAR_2216|M.marinum_M LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
MUL_1803|M.ulcerans_Agy99 LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
MAV_3371|M.avium_104 LRRHPVSALDARPLFEPVAD-LGDGPHVQLWPHRHGTDAMFAAALRREAG
Mflv_3729|M.gilvum_PYR-GCK LRRQPVTALDTGELFSPATD-TGDGPSVQLWPHRHGTDAMFAAALRVDAA
Mvan_2688|M.vanbaalenii_PYR-1 LRRHPVTALDTRELFEPATD-TGDGTSVQLWPHRHGTDAMFAAALRVN--
MSMEG_3065|M.smegmatis_MC2_155 IRRHPVTAMDTRPLFAPVDD-LGAGPHVQLWPHRHGTDAMFAAALRVDPD
MAB_2810c|M.abscessus_ATCC_199 VRRYAVSAEDARAVFPGVAG-LGDADAVQLWPHRHGTDAMFTALLRKHA-
TH_2937|M.thermoresistible__bu ALRPHAGPAGTVGFTA---------PYVIVTARRRG--------------
* . . .: . * : .:*:*
Mb1442|M.bovis_AF2122/97 --
Rv1407|M.tuberculosis_H37Rv --
MMAR_2216|M.marinum_M --
MUL_1803|M.ulcerans_Agy99 --
MAV_3371|M.avium_104 --
Mflv_3729|M.gilvum_PYR-GCK AR
Mvan_2688|M.vanbaalenii_PYR-1 --
MSMEG_3065|M.smegmatis_MC2_155 VR
MAB_2810c|M.abscessus_ATCC_199 --
TH_2937|M.thermoresistible__bu --