For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VKPNHPPRKRPPRRKPLDPARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACRSL GLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTVEQAGIEFDSARAGFVNGVLRTI SGRDEQAWIAELAPSAETDPVGHTAFVHAHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTA ITAEELAEQAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAEVDGTDEGRWLDL CSGPGGKTALLASIGAASGARVTAVEPAERRADLVEENTRGLGVEVHRVDGRESGLQPGFDRVLVDAPCT GLGALRRRPESRWRRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADAIRRHPVT AMDTRPLFAPVDDLGAGPHVQLWPHRHGTDAMFAAALRVDPDVR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3065 | sun | - | 100% (464) | ribosomal RNA small subunit methyltransferase B |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1442 | fmu | 0.0 | 79.47% (453) | Fmu protein (SUN protein) |
M. gilvum PYR-GCK | Mflv_3729 | - | 0.0 | 81.05% (459) | Fmu (Sun) domain-containing protein |
M. tuberculosis H37Rv | Rv1407 | fmu | 0.0 | 79.47% (453) | Fmu protein (SUN protein) |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2810c | - | 1e-173 | 67.60% (466) | Fmu protein (SUN protein) |
M. marinum M | MMAR_2216 | fmu | 0.0 | 77.53% (454) | Fmu protein |
M. avium 104 | MAV_3371 | - | 0.0 | 82.80% (436) | Fmu protein |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_1803 | fmu | 0.0 | 76.65% (454) | Fmu protein |
M. vanbaalenii PYR-1 | Mvan_2688 | - | 0.0 | 80.80% (448) | Fmu (Sun) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3729|M.gilvum_PYR-GCK ----------------------MTRPDKKRPPR------------RKRLD Mvan_2688|M.vanbaalenii_PYR-1 -------------------------------MK------------RKRLD MSMEG_3065|M.smegmatis_MC2_155 --------------------MKPNHPPRKRPPR------------RKPLD Mb1442|M.bovis_AF2122/97 ------------------------MTPRSRGPR------------RRPLD Rv1407|M.tuberculosis_H37Rv ------------------------MTPRSRGPR------------RRPLD MMAR_2216|M.marinum_M MSPGQDKRQRNRPDRKPRRSEGTGVPNQRRGPR------------RRPLD MUL_1803|M.ulcerans_Agy99 ------------------------MPNQRRGPR------------RRPLD MAV_3371|M.avium_104 -------------------------------------------------- MAB_2810c|M.abscessus_ATCC_199 ---------------------MSTRPPRRRSNQDSRRSAGPAERARRKLD Mflv_3729|M.gilvum_PYR-GCK PARQAAFDVLRAVSERDSYANLALPALLRDRRITGRDAAFATELTYGTCR Mvan_2688|M.vanbaalenii_PYR-1 PARQAAFDVLRAVSERDAYANLALPALLRDRGITGRDAAFATELTYGTCR MSMEG_3065|M.smegmatis_MC2_155 PARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACR Mb1442|M.bovis_AF2122/97 PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR Rv1407|M.tuberculosis_H37Rv PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR MMAR_2216|M.marinum_M PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAAFATELTYGACR MUL_1803|M.ulcerans_Agy99 PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAALATELTYGACR MAV_3371|M.avium_104 --------MLRAVSERDAYANLALPALLRERGITGRDAAFATELTYGTCR MAB_2810c|M.abscessus_ATCC_199 PPRQAALDVLRAVSRQDAYANLALPALLRERGITGRDAAFATELTYGTCR ***** :::****.***:* :* * *****:*******:** Mflv_3729|M.gilvum_PYR-GCK AKGLLDAVIAAAAGRPVDHIDPILLDLLRLGAYQILRTRVDDHAAVSTTV Mvan_2688|M.vanbaalenii_PYR-1 TRGLLDAVIAAAAGRPVDKIDPVLLDLLRLGSYQLLRTRVDDHAAVSTTV MSMEG_3065|M.smegmatis_MC2_155 SLGLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTV Mb1442|M.bovis_AF2122/97 ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV Rv1407|M.tuberculosis_H37Rv ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV MMAR_2216|M.marinum_M ARGLLDAIIGAAAGRSPEAIDPVLLDLLRLGAYQLLRTRVDAHAAVSTTV MUL_1803|M.ulcerans_Agy99 ARGLLDAIIGAAAGRSPEAIDPFLLDLLRLGAYQLLRTRVDAHAAVSTTV MAV_3371|M.avium_104 TRGLLDAVIGAAAGRPPEAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV MAB_2810c|M.abscessus_ATCC_199 ARGLLDAVIEAAAGRTIDQVDEGLRDPLRLGAYQLLRTRVEPHAALSTTV : *****:* ** *. : :* * * ****:**:*****: ***:**** Mflv_3729|M.gilvum_PYR-GCK EQAGLEFDTARAGFVNGVLRTIARRDEADWVAELAPPAATDPVGHLAFVH Mvan_2688|M.vanbaalenii_PYR-1 DQAGIEFDSSRAGFVNGVLRTIARRDEASWVEELAPSATGDPIGHLAFVH MSMEG_3065|M.smegmatis_MC2_155 EQAGIEFDSARAGFVNGVLRTISGRDEQAWIAELAPSAETDPVGHTAFVH Mb1442|M.bovis_AF2122/97 EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH Rv1407|M.tuberculosis_H37Rv EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH MMAR_2216|M.marinum_M EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH MUL_1803|M.ulcerans_Agy99 EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH MAV_3371|M.avium_104 EQAAIEFDSARAGFVNGVLRRIAGRDERSWVQELAPDPARDPIGHAAFVH MAB_2810c|M.abscessus_ATCC_199 DAVAVEFDQGRAGFVNAVLRTISRRDEADWVEELAP-PESDRIGRLAFAT : ..:*** .******.*** *: *** *: **** . * :*: **. Mflv_3729|M.gilvum_PYR-GCK AHPRWIGQAFADALGARAGELGALLASDDSRPEVHLAARPGMLTAAELAE Mvan_2688|M.vanbaalenii_PYR-1 AHPRWVAQAFADALGARAGELGALLASDDSRPEVHLVARPGALTAAELAE MSMEG_3065|M.smegmatis_MC2_155 AHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTAITAEELAE Mb1442|M.bovis_AF2122/97 AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR Rv1407|M.tuberculosis_H37Rv AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR MMAR_2216|M.marinum_M AHPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD MUL_1803|M.ulcerans_Agy99 THPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD MAV_3371|M.avium_104 AHPRWIAQAFADALGAAAAELDAVLASDDERPQVHLAARPGALTAAELAD MAB_2810c|M.abscessus_ATCC_199 AHPRWIAQSFSDALGPAGSELAQVLASDDERPLVHLAARPGRIDAEALAE :****:.*:*:****. .** :***** ** ***.*** : * ** Mflv_3729|M.gilvum_PYR-GCK QTGGTVGRYSPYAVYLGDGDPGGVAAVRESRALVQDEGSQLVARALTLAP Mvan_2688|M.vanbaalenii_PYR-1 QVGGGVGRYSPYAVYLGEGDPGQLAAVREGTALVQDEGSQLVARALTLAP MSMEG_3065|M.smegmatis_MC2_155 QAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAE Mb1442|M.bovis_AF2122/97 AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP Rv1407|M.tuberculosis_H37Rv AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP MMAR_2216|M.marinum_M EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP MUL_1803|M.ulcerans_Agy99 EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP MAV_3371|M.avium_104 AVGGTVGRHSPFAVYLAGGDPGRLAPVRDGLALVQDEGSQLVARALTLAP MAB_2810c|M.abscessus_ATCC_199 AVGGTVGRYSPFAVYLPGGDPGRLEPVRDGLAQVQDEGSQLIARATALAP . * ***:**:**** **** : .**:. * ********:*** :** Mflv_3729|M.gilvum_PYR-GCK VDGPDGGRWLDLCAGPGGKTALLAALGQPSGA----TVTAVEPAPRRAEL Mvan_2688|M.vanbaalenii_PYR-1 LVGPDGGRWLDLCAGPGGKTALLAALGAPEGV----TVTAVEPAPRRADL MSMEG_3065|M.smegmatis_MC2_155 VDGTDEGRWLDLCSGPGGKTALLASIGAASGA----RVTAVEPAERRADL Mb1442|M.bovis_AF2122/97 VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL Rv1407|M.tuberculosis_H37Rv VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL MMAR_2216|M.marinum_M VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL MUL_1803|M.ulcerans_Agy99 VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL MAV_3371|M.avium_104 VDG-DCGRWLDLCAGPGGKTALLASLGAQRFSGPQFRVTAVEPAPRRADL MAB_2810c|M.abscessus_ATCC_199 LQG-ADEQWLDLCAGPGGKTALLGALAAQRGA----HVTAVEVAPHRAEL : * :*****:*********..:. ***** : :**:* Mflv_3729|M.gilvum_PYR-GCK VEQNTAGLPVDVVRVDGRESGLTPG-FDRVLVDAPCTGLGALRRRPEARW Mvan_2688|M.vanbaalenii_PYR-1 VEQNTAGLPVEVVRVDGREPGLAPG-FDRVLVDAPCTGLGALRRRPEARW MSMEG_3065|M.smegmatis_MC2_155 VEENTRGLGVEVHRVDGRESGLQPG-FDRVLVDAPCTGLGALRRRPESRW Mb1442|M.bovis_AF2122/97 VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW Rv1407|M.tuberculosis_H37Rv VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW MMAR_2216|M.marinum_M VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW MUL_1803|M.ulcerans_Agy99 VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW MAV_3371|M.avium_104 VVENTRGLPVEVLRVDGRHTGLQPA-FDRVLVDAPCTGLGALRRRPEARW MAB_2810c|M.abscessus_ATCC_199 VANATKSLPVTVVTADGRDSDLAAASFDRVLVDAPCTGLGALRRRPEARW * : * .* * : *** ..* . *********************:** Mflv_3729|M.gilvum_PYR-GCK RRQPGDVPALAKLQRELLAAAIRLTRPGGVVLYATCSPHLAETAGVVADA Mvan_2688|M.vanbaalenii_PYR-1 RRQPGDVPPLAKLQRELLASAIRLTRPGGVVLYATCSPHLAETAGVVADA MSMEG_3065|M.smegmatis_MC2_155 RRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADA Mb1442|M.bovis_AF2122/97 RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA Rv1407|M.tuberculosis_H37Rv RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA MMAR_2216|M.marinum_M RRQPSDVPTLVKLQRELLAAAINLTRPGGVVLYATCSPHLAETVGVVADA MUL_1803|M.ulcerans_Agy99 RRQPSDVPTLVKLQRELLAAAINLTRPGGVVFYATCSPHLAETVGVVADA MAV_3371|M.avium_104 RRQPGDVPTLTKLQRELLGAAIALTRPGGVVLYATCSPHLAETVGVVADA MAB_2810c|M.abscessus_ATCC_199 RRQPGDIPELVKLQRELLASAIQLTRPGGVIVYSTCSPHLAETVGVVSDA ****.*:. *.:******.:** *******:.*:*********.*.*:** Mflv_3729|M.gilvum_PYR-GCK LRRQPVTALDTGELFSPATD-TGDGPSVQLWPHRHGTDAMFAAALRVDAA Mvan_2688|M.vanbaalenii_PYR-1 LRRHPVTALDTRELFEPATD-TGDGTSVQLWPHRHGTDAMFAAALRVN-- MSMEG_3065|M.smegmatis_MC2_155 IRRHPVTAMDTRPLFAPVDD-LGAGPHVQLWPHRHGTDAMFAAALRVDPD Mb1442|M.bovis_AF2122/97 LRRHPVHALDTRPLFEPVLAGLGEGPHVQLWPHRHGTDAMFAAALRRLT- Rv1407|M.tuberculosis_H37Rv LRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT- MMAR_2216|M.marinum_M LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA- MUL_1803|M.ulcerans_Agy99 LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA- MAV_3371|M.avium_104 LRRHPVSALDARPLFEPVAD-LGDGPHVQLWPHRHGTDAMFAAALRREAG MAB_2810c|M.abscessus_ATCC_199 VRRYAVSAEDARAVFPGVAG-LGDADAVQLWPHRHGTDAMFTALLRKHA- :** .* * *: :* * . **************:* ** Mflv_3729|M.gilvum_PYR-GCK AR Mvan_2688|M.vanbaalenii_PYR-1 -- MSMEG_3065|M.smegmatis_MC2_155 VR Mb1442|M.bovis_AF2122/97 -- Rv1407|M.tuberculosis_H37Rv -- MMAR_2216|M.marinum_M -- MUL_1803|M.ulcerans_Agy99 -- MAV_3371|M.avium_104 -- MAB_2810c|M.abscessus_ATCC_199 --