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M. smegmatis MC2 155 MSMEG_3065 (sun)

annotation: ribosomal RNA small subunit methyltransferase B
coordinates: 3138801 - 3140195
length: 464

VKPNHPPRKRPPRRKPLDPARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACRSL
GLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTVEQAGIEFDSARAGFVNGVLRTI
SGRDEQAWIAELAPSAETDPVGHTAFVHAHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTA
ITAEELAEQAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAEVDGTDEGRWLDL
CSGPGGKTALLASIGAASGARVTAVEPAERRADLVEENTRGLGVEVHRVDGRESGLQPGFDRVLVDAPCT
GLGALRRRPESRWRRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADAIRRHPVT
AMDTRPLFAPVDDLGAGPHVQLWPHRHGTDAMFAAALRVDPDVR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3065sun-100% (464)ribosomal RNA small subunit methyltransferase B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1442fmu0.079.47% (453) Fmu protein (SUN protein)
M. gilvum PYR-GCKMflv_3729-0.081.05% (459) Fmu (Sun) domain-containing protein
M. tuberculosis H37RvRv1407fmu0.079.47% (453) Fmu protein (SUN protein)
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2810c-1e-17367.60% (466) Fmu protein (SUN protein)
M. marinum MMMAR_2216fmu0.077.53% (454) Fmu protein
M. avium 104MAV_3371-0.082.80% (436) Fmu protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1803fmu0.076.65% (454) Fmu protein
M. vanbaalenii PYR-1Mvan_2688-0.080.80% (448) Fmu (Sun) domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3729|M.gilvum_PYR-GCK          ----------------------MTRPDKKRPPR------------RKRLD
Mvan_2688|M.vanbaalenii_PYR-1       -------------------------------MK------------RKRLD
MSMEG_3065|M.smegmatis_MC2_155      --------------------MKPNHPPRKRPPR------------RKPLD
Mb1442|M.bovis_AF2122/97            ------------------------MTPRSRGPR------------RRPLD
Rv1407|M.tuberculosis_H37Rv         ------------------------MTPRSRGPR------------RRPLD
MMAR_2216|M.marinum_M               MSPGQDKRQRNRPDRKPRRSEGTGVPNQRRGPR------------RRPLD
MUL_1803|M.ulcerans_Agy99           ------------------------MPNQRRGPR------------RRPLD
MAV_3371|M.avium_104                --------------------------------------------------
MAB_2810c|M.abscessus_ATCC_199      ---------------------MSTRPPRRRSNQDSRRSAGPAERARRKLD
                                                                                      

Mflv_3729|M.gilvum_PYR-GCK          PARQAAFDVLRAVSERDSYANLALPALLRDRRITGRDAAFATELTYGTCR
Mvan_2688|M.vanbaalenii_PYR-1       PARQAAFDVLRAVSERDAYANLALPALLRDRGITGRDAAFATELTYGTCR
MSMEG_3065|M.smegmatis_MC2_155      PARRVAFDVLRAVSERDAYANLALPAMLRERGIDGRDAAFATELTYGACR
Mb1442|M.bovis_AF2122/97            PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
Rv1407|M.tuberculosis_H37Rv         PARRAAFETLRAVSARDAYANLVLPALLAQRGIGGRDAAFATELTYGTCR
MMAR_2216|M.marinum_M               PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAAFATELTYGACR
MUL_1803|M.ulcerans_Agy99           PARGAAFNALRAVSERNAYANLVLPALLRERGITGRDAALATELTYGACR
MAV_3371|M.avium_104                --------MLRAVSERDAYANLALPALLRERGITGRDAAFATELTYGTCR
MAB_2810c|M.abscessus_ATCC_199      PPRQAALDVLRAVSRQDAYANLALPALLRERGITGRDAAFATELTYGTCR
                                             ***** :::****.***:* :* * *****:*******:**

Mflv_3729|M.gilvum_PYR-GCK          AKGLLDAVIAAAAGRPVDHIDPILLDLLRLGAYQILRTRVDDHAAVSTTV
Mvan_2688|M.vanbaalenii_PYR-1       TRGLLDAVIAAAAGRPVDKIDPVLLDLLRLGSYQLLRTRVDDHAAVSTTV
MSMEG_3065|M.smegmatis_MC2_155      SLGLLDAVIERAAGRPTDRIDPVLLDLLRLGTYQLLRTRVEPHAAVSTTV
Mb1442|M.bovis_AF2122/97            ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
Rv1407|M.tuberculosis_H37Rv         ARGLLDAVIGAAAERSPQAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
MMAR_2216|M.marinum_M               ARGLLDAIIGAAAGRSPEAIDPVLLDLLRLGAYQLLRTRVDAHAAVSTTV
MUL_1803|M.ulcerans_Agy99           ARGLLDAIIGAAAGRSPEAIDPFLLDLLRLGAYQLLRTRVDAHAAVSTTV
MAV_3371|M.avium_104                TRGLLDAVIGAAAGRPPEAIDPVLLDLLRLGTYQLLRTRVDAHAAVSTTV
MAB_2810c|M.abscessus_ATCC_199      ARGLLDAVIEAAAGRTIDQVDEGLRDPLRLGAYQLLRTRVEPHAALSTTV
                                    : *****:*  ** *. : :*  * * ****:**:*****: ***:****

Mflv_3729|M.gilvum_PYR-GCK          EQAGLEFDTARAGFVNGVLRTIARRDEADWVAELAPPAATDPVGHLAFVH
Mvan_2688|M.vanbaalenii_PYR-1       DQAGIEFDSSRAGFVNGVLRTIARRDEASWVEELAPSATGDPIGHLAFVH
MSMEG_3065|M.smegmatis_MC2_155      EQAGIEFDSARAGFVNGVLRTISGRDEQAWIAELAPSAETDPVGHTAFVH
Mb1442|M.bovis_AF2122/97            EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
Rv1407|M.tuberculosis_H37Rv         EQAGIEFDSARAGFVNGVLRTIAGRDERSWVGELAPDAQNDPIGHAAFVH
MMAR_2216|M.marinum_M               EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
MUL_1803|M.ulcerans_Agy99           EQAGIEFDSARAGFVNAVLRTIADRDEQSWVQELAPDPRRDPVGHAAFVH
MAV_3371|M.avium_104                EQAAIEFDSARAGFVNGVLRRIAGRDERSWVQELAPDPARDPIGHAAFVH
MAB_2810c|M.abscessus_ATCC_199      DAVAVEFDQGRAGFVNAVLRTISRRDEADWVEELAP-PESDRIGRLAFAT
                                    : ..:*** .******.*** *: ***  *: **** .  * :*: **. 

Mflv_3729|M.gilvum_PYR-GCK          AHPRWIGQAFADALGARAGELGALLASDDSRPEVHLAARPGMLTAAELAE
Mvan_2688|M.vanbaalenii_PYR-1       AHPRWVAQAFADALGARAGELGALLASDDSRPEVHLVARPGALTAAELAE
MSMEG_3065|M.smegmatis_MC2_155      AHPRWIAQAFTDALGAAAGELDALLASDDARPVVHLAARPTAITAEELAE
Mb1442|M.bovis_AF2122/97            AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
Rv1407|M.tuberculosis_H37Rv         AHPRWIAQAFADALGAAVGELEAVLASDDERPAVHLAARPGVLTAGELAR
MMAR_2216|M.marinum_M               AHPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
MUL_1803|M.ulcerans_Agy99           THPRWIAQAFADALGPSAAELDAVLASDDERPQVHLAARPGVLTAAALAD
MAV_3371|M.avium_104                AHPRWIAQAFADALGAAAAELDAVLASDDERPQVHLAARPGALTAAELAD
MAB_2810c|M.abscessus_ATCC_199      AHPRWIAQSFSDALGPAGSELAQVLASDDERPLVHLAARPGRIDAEALAE
                                    :****:.*:*:****.  .**  :***** ** ***.***  : *  ** 

Mflv_3729|M.gilvum_PYR-GCK          QTGGTVGRYSPYAVYLGDGDPGGVAAVRESRALVQDEGSQLVARALTLAP
Mvan_2688|M.vanbaalenii_PYR-1       QVGGGVGRYSPYAVYLGEGDPGQLAAVREGTALVQDEGSQLVARALTLAP
MSMEG_3065|M.smegmatis_MC2_155      QAGGTVGRYSPYAVYLTGGDPGRVPAVRDGAAQVQDEGSQLVARALTLAE
Mb1442|M.bovis_AF2122/97            AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
Rv1407|M.tuberculosis_H37Rv         AVRGTVGRYSPFAVYLPRGDPGRLAPVRDGQALVQDEGSQLVARALTLAP
MMAR_2216|M.marinum_M               EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
MUL_1803|M.ulcerans_Agy99           EVRGTVGRYSPYAVYLLGGDPGLLAPVRDGQALVQDEGSQLVARALTLAP
MAV_3371|M.avium_104                AVGGTVGRHSPFAVYLAGGDPGRLAPVRDGLALVQDEGSQLVARALTLAP
MAB_2810c|M.abscessus_ATCC_199      AVGGTVGRYSPFAVYLPGGDPGRLEPVRDGLAQVQDEGSQLIARATALAP
                                     . * ***:**:****  **** : .**:. * ********:*** :** 

Mflv_3729|M.gilvum_PYR-GCK          VDGPDGGRWLDLCAGPGGKTALLAALGQPSGA----TVTAVEPAPRRAEL
Mvan_2688|M.vanbaalenii_PYR-1       LVGPDGGRWLDLCAGPGGKTALLAALGAPEGV----TVTAVEPAPRRADL
MSMEG_3065|M.smegmatis_MC2_155      VDGTDEGRWLDLCSGPGGKTALLASIGAASGA----RVTAVEPAERRADL
Mb1442|M.bovis_AF2122/97            VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
Rv1407|M.tuberculosis_H37Rv         VDG-DTGRWLDLCAGPGGKTALLAGLGLQCAA----RVTAVEPSPHRADL
MMAR_2216|M.marinum_M               VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
MUL_1803|M.ulcerans_Agy99           VEG-DSGRWLDLCAGPGGKTALLAALGVATGA----RVTAVEPSSHRADL
MAV_3371|M.avium_104                VDG-DCGRWLDLCAGPGGKTALLASLGAQRFSGPQFRVTAVEPAPRRADL
MAB_2810c|M.abscessus_ATCC_199      LQG-ADEQWLDLCAGPGGKTALLGALAAQRGA----HVTAVEVAPHRAEL
                                    : *    :*****:*********..:.          ***** : :**:*

Mflv_3729|M.gilvum_PYR-GCK          VEQNTAGLPVDVVRVDGRESGLTPG-FDRVLVDAPCTGLGALRRRPEARW
Mvan_2688|M.vanbaalenii_PYR-1       VEQNTAGLPVEVVRVDGREPGLAPG-FDRVLVDAPCTGLGALRRRPEARW
MSMEG_3065|M.smegmatis_MC2_155      VEENTRGLGVEVHRVDGRESGLQPG-FDRVLVDAPCTGLGALRRRPESRW
Mb1442|M.bovis_AF2122/97            VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
Rv1407|M.tuberculosis_H37Rv         VAQNTRGLPVELLRVDGRHTDLDPG-FDRVLVDAPCTGLGALRRRPEARW
MMAR_2216|M.marinum_M               VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
MUL_1803|M.ulcerans_Agy99           VADNTGGLPVDLVRGDGRYTDLEPV-FDRVLVDAPCTGLGALRRRPEARW
MAV_3371|M.avium_104                VVENTRGLPVEVLRVDGRHTGLQPA-FDRVLVDAPCTGLGALRRRPEARW
MAB_2810c|M.abscessus_ATCC_199      VANATKSLPVTVVTADGRDSDLAAASFDRVLVDAPCTGLGALRRRPEARW
                                    * : * .* * :   *** ..* .  *********************:**

Mflv_3729|M.gilvum_PYR-GCK          RRQPGDVPALAKLQRELLAAAIRLTRPGGVVLYATCSPHLAETAGVVADA
Mvan_2688|M.vanbaalenii_PYR-1       RRQPGDVPPLAKLQRELLASAIRLTRPGGVVLYATCSPHLAETAGVVADA
MSMEG_3065|M.smegmatis_MC2_155      RRQPGDVAALTRLQRELLAAAIRLTRPGGVVLYATCSPHLAETVGVVADA
Mb1442|M.bovis_AF2122/97            RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
Rv1407|M.tuberculosis_H37Rv         RRQPADVAALAKLQRELLSAAIALTRPGGVVLYATCSPHLAETVGAVADA
MMAR_2216|M.marinum_M               RRQPSDVPTLVKLQRELLAAAINLTRPGGVVLYATCSPHLAETVGVVADA
MUL_1803|M.ulcerans_Agy99           RRQPSDVPTLVKLQRELLAAAINLTRPGGVVFYATCSPHLAETVGVVADA
MAV_3371|M.avium_104                RRQPGDVPTLTKLQRELLGAAIALTRPGGVVLYATCSPHLAETVGVVADA
MAB_2810c|M.abscessus_ATCC_199      RRQPGDIPELVKLQRELLASAIQLTRPGGVIVYSTCSPHLAETVGVVSDA
                                    ****.*:. *.:******.:** *******:.*:*********.*.*:**

Mflv_3729|M.gilvum_PYR-GCK          LRRQPVTALDTGELFSPATD-TGDGPSVQLWPHRHGTDAMFAAALRVDAA
Mvan_2688|M.vanbaalenii_PYR-1       LRRHPVTALDTRELFEPATD-TGDGTSVQLWPHRHGTDAMFAAALRVN--
MSMEG_3065|M.smegmatis_MC2_155      IRRHPVTAMDTRPLFAPVDD-LGAGPHVQLWPHRHGTDAMFAAALRVDPD
Mb1442|M.bovis_AF2122/97            LRRHPVHALDTRPLFEPVLAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
Rv1407|M.tuberculosis_H37Rv         LRRHPVHALDTRPLFEPVIAGLGEGPHVQLWPHRHGTDAMFAAALRRLT-
MMAR_2216|M.marinum_M               LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
MUL_1803|M.ulcerans_Agy99           LRRHPVDALDTRALFEPITEGLGEGPYVQLWPHRHGTDAMFAAALRRRA-
MAV_3371|M.avium_104                LRRHPVSALDARPLFEPVAD-LGDGPHVQLWPHRHGTDAMFAAALRREAG
MAB_2810c|M.abscessus_ATCC_199      VRRYAVSAEDARAVFPGVAG-LGDADAVQLWPHRHGTDAMFTALLRKHA-
                                    :** .* * *:  :*       * .  **************:* **    

Mflv_3729|M.gilvum_PYR-GCK          AR
Mvan_2688|M.vanbaalenii_PYR-1       --
MSMEG_3065|M.smegmatis_MC2_155      VR
Mb1442|M.bovis_AF2122/97            --
Rv1407|M.tuberculosis_H37Rv         --
MMAR_2216|M.marinum_M               --
MUL_1803|M.ulcerans_Agy99           --
MAV_3371|M.avium_104                --
MAB_2810c|M.abscessus_ATCC_199      --