For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSTNQGSLWGGRFAGGPSDALAALSKSTHFDWALAPYDVTASRAHAVVLFRAGLLTEEQRDGLLAGLDSL ASDVADGSFGPLVSDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVATGVLEV VAALGDQAAAHPTAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDVERIVDFDKRAAVSPYGSGALAGSSL GLDPDAIAADLGFTTAADNSVDATASRDFAAEAAFVFAMIAVDLSRLAEDIIIWSSTEFGYVTLHDSWST GSSIMPQKKNPDIAELARGKSGRLIGNLTGLLATLKSQPLAYNRDLQEDKEPVFDSVVQLELLLPAMAGL VGSLTFDVERMAALAPAGYTLATDVAEWLVRQGVPFRSAHEAAGAAVRTAEERSVGLEELTDDELAAISP ELTPQVRDVLTIEGSVSARDSRGGTAPKRVAEQLQIVREITARLGHELMR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1651 | argH | - | 100% (470) | argininosuccinate lyase |
M. ulcerans Agy99 | MUL_0181 | fumC | 5e-13 | 24.54% (432) | fumarate hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1687 | argH | 0.0 | 90.43% (470) | argininosuccinate lyase |
M. gilvum PYR-GCK | Mflv_3523 | - | 0.0 | 85.11% (470) | argininosuccinate lyase |
M. tuberculosis H37Rv | Rv1659 | argH | 0.0 | 90.43% (470) | argininosuccinate lyase |
M. leprae Br4923 | MLBr_01413 | argH | 0.0 | 86.60% (470) | argininosuccinate lyase |
M. abscessus ATCC 19977 | MAB_2343 | - | 0.0 | 79.43% (457) | argininosuccinate lyase ArgH |
M. marinum M | MMAR_2469 | argH | 0.0 | 99.36% (470) | argininosuccinate lyase ArgH |
M. avium 104 | MAV_3111 | argH | 0.0 | 87.61% (468) | argininosuccinate lyase |
M. smegmatis MC2 155 | MSMEG_3769 | argH | 0.0 | 85.99% (464) | argininosuccinate lyase |
M. thermoresistible (build 8) | TH_1599 | argH | 0.0 | 83.62% (464) | Probable Argininosuccinate lyase argH |
M. vanbaalenii PYR-1 | Mvan_3307 | - | 0.0 | 84.68% (470) | argininosuccinate lyase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3523|M.gilvum_PYR-GCK MSTNEGSLWGGRFADGPADALAALSKSTHFDWVLAPYDVVASKAHARVLF Mvan_3307|M.vanbaalenii_PYR-1 MSTNEGSLWGGRFADGPADALAALSKSTHFDWVLAPYDVVASKAHARVLF MUL_1651|M.ulcerans_Agy99 MSTNQGSLWGGRFAGGPSDALAALSKSTHFDWALAPYDVTASRAHAVVLF MMAR_2469|M.marinum_M MSTNQGSLWGGRFAGGPSDALAALSKSTHFDWALAPYDVTASRAHAVVLF Mb1687|M.bovis_AF2122/97 MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLF Rv1659|M.tuberculosis_H37Rv MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLF MLBr_01413|M.leprae_Br4923 MSTNQGSLWGGRFAAGPSEALVALSKSTHFDWVLAPYDITASRAHTKMLF MAV_3111|M.avium_104 MSTREGSLWGGRFADGPSDALAALSKSTHFDWVLAPYDIVASRAHTVILY MSMEG_3769|M.smegmatis_MC2_155 MSTNEGSLWGGRFADGPSDALAALSKSTHFDWALAPYDIKASKAHARVLH TH_1599|M.thermoresistible__bu VSTNKGSLWGGRFAGGPSDALAALSKSTHFDWALAPYDITASKAHVRVLH MAB_2343|M.abscessus_ATCC_1997 MSTNEGSLWGGRFAGGPAPALAALSKSTHFDWALAPYDIQASVAHARVLR :**.:********* **: **.**********.*****: ** **. :* Mflv_3523|M.gilvum_PYR-GCK RAGLLTEEQRDGLLAGLDSLGSDVADGSFGPLVSDEDVHGALERGLIDRV Mvan_3307|M.vanbaalenii_PYR-1 RAGLLTEEQRDGLLAGLDSLGSDVADGSFGPLVSDEDVHGALERGLIDRV MUL_1651|M.ulcerans_Agy99 RAGLLTEEQRDGLLAGLDSLASDVADGSFGPLVSDEDVHAALERGLIDRV MMAR_2469|M.marinum_M RAGLLTEEQRDGLLAGLDSLASDVADGSFGPLVSDEDVHAALERGLIERV Mb1687|M.bovis_AF2122/97 RAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRV Rv1659|M.tuberculosis_H37Rv RAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRV MLBr_01413|M.leprae_Br4923 RAGLLNEEQRDGLLAGLDNLAEDVADGSFLPLVTDEDVHAALERGLIDRV MAV_3111|M.avium_104 RAGLLSEEQRDGLLAGLDSLAEDVADGSFTPLVTDEDVHAALERGLIDRV MSMEG_3769|M.smegmatis_MC2_155 RAGLLTDEQRDGLLAGLDSLGSDVADGSFEPLPTDEDVHGALERGLIDRV TH_1599|M.thermoresistible__bu RAGLLTDEQRDGLLDGLDRLADDVAAGRFVPDDTDEDVHGALERGLIERV MAB_2343|M.abscessus_ATCC_1997 KAGLLTDEQLGALVEGLEQLGRDVASGVFVPADTDEDVHGALERGLIERV :****.:** ..*: **: *. *** * * * :*****.*******:** Mflv_3523|M.gilvum_PYR-GCK GPELGGRLRAGRSRNDQVATLFRLWLRDAVRRVADGVLEVVGALTTQAAA Mvan_3307|M.vanbaalenii_PYR-1 GADLGGRLRAGRSRNDQVATLFRLWLRDAIRRVADGVLEVVAALATQAAA MUL_1651|M.ulcerans_Agy99 GPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVATGVLEVVAALGDQAAA MMAR_2469|M.marinum_M GPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVATGVLEVVAALGDQAAA Mb1687|M.bovis_AF2122/97 GPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAA Rv1659|M.tuberculosis_H37Rv GPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAA MLBr_01413|M.leprae_Br4923 GPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVAAGALEVVDALANQAAE MAV_3111|M.avium_104 GPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVAAGALDVVGALVAQAAA MSMEG_3769|M.smegmatis_MC2_155 GPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVADGCLEVVNALAVQAAA TH_1599|M.thermoresistible__bu GPELGGRLRAGRSRNDQVATLFRLWLRDAVRSVGAGVLDVVDALADQAAA MAB_2343|M.abscessus_ATCC_1997 GPDIGGRLRAGRSRNDQVATLFRMWLRDAAGRISEGVLDVVQALADQAGA *.::***************:***:***** :. * *:** ** **. Mflv_3523|M.gilvum_PYR-GCK HPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRLADFDKRAAVSPY Mvan_3307|M.vanbaalenii_PYR-1 HPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRLADFDKRAAVSPY MUL_1651|M.ulcerans_Agy99 HPTAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDVERIVDFDKRAAVSPY MMAR_2469|M.marinum_M HPTAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDVERIVDFDKRAAVSPY Mb1687|M.bovis_AF2122/97 HPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPY Rv1659|M.tuberculosis_H37Rv HPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPY MLBr_01413|M.leprae_Br4923 HSSTIMPGKTHLQSAQPILLAHHLLAHAHPLLRDVGRIVDFDKRAAVSPY MAV_3111|M.avium_104 HPEAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRIVDFDKRAAVSPY MSMEG_3769|M.smegmatis_MC2_155 HPTAIMPGKTHLQAAQPILLAHHLLAHAHPLLRDVDRLADFDDRTAVSPY TH_1599|M.thermoresistible__bu HPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRLLDFDRRAAVSPY MAB_2343|M.abscessus_ATCC_1997 HPDAIMPGKTHLQAAQPVLLAHHLLAHAQPLLRDVDRLVDWDRRTAVSPY *. :*********:***:**********:*****: *: *:* *:***** Mflv_3523|M.gilvum_PYR-GCK GSGALAGSSLGLDPDAIAEELGFAAAADNSIDATASRDFAAEAAFVFSMI Mvan_3307|M.vanbaalenii_PYR-1 GSGALAGSSLGLDPDAIAEELGFAAAADNSIDATASRDFAAEAAFVFSMI MUL_1651|M.ulcerans_Agy99 GSGALAGSSLGLDPDAIAADLGFTTAADNSVDATASRDFAAEAAFVFAMI MMAR_2469|M.marinum_M GSGALAGSSLGLDPDAIAADLGFTTAADNSVDATASRDFAAEAAFIFAMI Mb1687|M.bovis_AF2122/97 GSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMI Rv1659|M.tuberculosis_H37Rv GSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFAAEAAFVFAMI MLBr_01413|M.leprae_Br4923 GSGALAGSSLGLDPDAMAQDLGFPAAADNSVDATAARDFAAEAAFVFAMI MAV_3111|M.avium_104 GSGALAGSSLGLDPDAIAAELGFASAADNSIDATASRDFAAEAAFVFAMI MSMEG_3769|M.smegmatis_MC2_155 GSGALAGSSLGLDPDAIAEDLGFASAADNSVDATASRDFAAEAAFVFAQI TH_1599|M.thermoresistible__bu GSGALAGSSLGLDPDAIAEELGFSAAADNSIDATAARDFAAEAAFVFAMT MAB_2343|M.abscessus_ATCC_1997 GAGALAGSSLGLDPDAIALDLGFTAAADNSIDATSSRDFAAEAGFVFAMI *:**************:* :***.:*****:***::*******.*:*: Mflv_3523|M.gilvum_PYR-GCK GVDLSRLAEDVILWSTTEFGYVELHDAWSTGSSIMPQKKNPDIAELARGK Mvan_3307|M.vanbaalenii_PYR-1 GVDLSRLAEDIILWSTTEFGYVTLHDAWSTGSSIMPQKKNPDIAELARGK MUL_1651|M.ulcerans_Agy99 AVDLSRLAEDIIIWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK MMAR_2469|M.marinum_M AVDLSRLAEDIIIWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK Mb1687|M.bovis_AF2122/97 AVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK Rv1659|M.tuberculosis_H37Rv AVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK MLBr_01413|M.leprae_Br4923 AVDLSRLAEDIILWSSTEFGYARLHDSWSTGSSIMPQKKNPDIAELARGK MAV_3111|M.avium_104 GVDLSRLAEDVILWSSTEFGYVKLHDAWSTGSSIMPQKKNPDIAELARGK MSMEG_3769|M.smegmatis_MC2_155 GVDLSRLAEDIILWSSTEFGYVTLHDAWSTGSSIMPQKKNPDIAELARGK TH_1599|M.thermoresistible__bu GVDLSRLAEDIILWSTTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK MAB_2343|M.abscessus_ATCC_1997 GIDLSRLSEDIILWGTTEFGYVTLDDSWSTGSSIMPQKKNPDIAELARGK .:*****:**:*:*.:*****. *.*:*********************** Mflv_3523|M.gilvum_PYR-GCK SGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL Mvan_3307|M.vanbaalenii_PYR-1 SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL MUL_1651|M.ulcerans_Agy99 SGRLIGNLTGLLATLKSQPLAYNRDLQEDKEPVFDSVVQLELLLPAMAGL MMAR_2469|M.marinum_M SGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVVQLELLLPAMAGL Mb1687|M.bovis_AF2122/97 SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL Rv1659|M.tuberculosis_H37Rv SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL MLBr_01413|M.leprae_Br4923 SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL MAV_3111|M.avium_104 SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDAVAQLELVLPAMAGL MSMEG_3769|M.smegmatis_MC2_155 SGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL TH_1599|M.thermoresistible__bu SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLRLLLPAMTGL MAB_2343|M.abscessus_ATCC_1997 TGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPLFDSVSQLELLLPAMAGL :*******:*******:***************:**:* **.*:****:** Mflv_3523|M.gilvum_PYR-GCK VATLRFDVDRMAELAPLGYTLATDVAEWLVRRGVPFRVAHEAAGAAVRAA Mvan_3307|M.vanbaalenii_PYR-1 VGTLRFDVDRMAELAPLGYTLATDVAEWLVRRGVPFRVAHEAAGAAVRAA MUL_1651|M.ulcerans_Agy99 VGSLTFDVERMAALAPAGYTLATDVAEWLVRQGVPFRSAHEAAGAAVRTA MMAR_2469|M.marinum_M VGSLTFDVERMAALAPAGYTLATDVAEWLVRQGVPFRSAHEAAGAAVRTA Mb1687|M.bovis_AF2122/97 VASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAA Rv1659|M.tuberculosis_H37Rv VASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAA MLBr_01413|M.leprae_Br4923 VASLTFNVERMAALAPAGYTLATDIAEWLVRQGVPFRSAHEAAGTAVRVA MAV_3111|M.avium_104 VGSLTFDVQRMAALAPAGYTLATDIAEWLVRQGVPFRSAHEAAGAAVRAA MSMEG_3769|M.smegmatis_MC2_155 VGTLTFDEERMAELAPAGYTLATDIAEWLVRQGVPFRIAHEAAGAAVKVA TH_1599|M.thermoresistible__bu VATLTFDTARMAELAPLGYTLATDMAEWLVRRGVPFRVAHEAAGAAVRAA MAB_2343|M.abscessus_ATCC_1997 VATLRFHTERMAQLAPAGFTLATDLAEWMVRQGIPFRVAHEAAGEAVRVA *.:* *. *** *** *:*****:***:**:*:*** ****** **:.* Mflv_3523|M.gilvum_PYR-GCK EARGVGLEELEDAELAGIHPELTAEVRDVLSTEGSVNSRDARGGTAPIQV Mvan_3307|M.vanbaalenii_PYR-1 EARGIGLEDLADAELTGIHPQLTADVREVLTTEGSVNSRDARGGTAPTQV MUL_1651|M.ulcerans_Agy99 EERSVGLEELTDDELAAISPELTPQVRDVLTIEGSVSARDSRGGTAPKRV MMAR_2469|M.marinum_M EERSVGLEELTDDELAAISPELTPQVRDVLTIEGSVSARDSRGGTAPKRV Mb1687|M.bovis_AF2122/97 EQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRV Rv1659|M.tuberculosis_H37Rv EQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRV MLBr_01413|M.leprae_Br4923 EGRGVGLEELTDDELAAISANLTPQVREVLTVEGSVSSRAARGGTAPSQA MAV_3111|M.avium_104 EQRAVGLDELTDDELAAISPALTPQVREVLTIEGSVSSRDARGGTAPARV MSMEG_3769|M.smegmatis_MC2_155 EGRGVGLDALTDDEFASINPALTPDVREVLTVEGSVNARNARGGTAPTQV TH_1599|M.thermoresistible__bu EARGIGLEELSDAELAEIHPELTPQVREVLTVEGSVNARDARGGTAPVQV MAB_2343|M.abscessus_ATCC_1997 EARGVGLEDLTDEEFAAIHPELTGDVRAVLTTAGSVASRDARGGTAPERV * *.:**: * * *:: * . ** :** **: *** :* .****** :. Mflv_3523|M.gilvum_PYR-GCK ARQLGAVRDTADELRRRLRR--- Mvan_3307|M.vanbaalenii_PYR-1 ARQLSAVRDTSERFRVRLRR--- MUL_1651|M.ulcerans_Agy99 AEQLQIVREITARLGHELMR--- MMAR_2469|M.marinum_M AEQLQIVREITARLGHELMR--- Mb1687|M.bovis_AF2122/97 AEQLNAIGEAAERLRRQLVR--- Rv1659|M.tuberculosis_H37Rv AEQLNAIGEAAERLRRQLVR--- MLBr_01413|M.leprae_Br4923 AKQLTVVRANANQLRQLLMR--- MAV_3111|M.avium_104 VEQIDTVAATAARLRERLGGPA- MSMEG_3769|M.smegmatis_MC2_155 AKQLGVVRKAMEELRIRLS---- TH_1599|M.thermoresistible__bu ARQLDLVRDTASRLRLRLEG--- MAB_2343|M.abscessus_ATCC_1997 AEQRELVLARLNVLRGQNGRHPG ..* : :