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M. ulcerans Agy99 MUL_1626 (lysS)

annotation: lysyl-tRNA synthetase
coordinates: 1767497 - 1770790
length: 1097

QSRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAA
LAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQFWTKVRRGAL
FKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGA
LALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGV
CLASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSG
PDMRGVRQAVTRARRAGLTVRIRRHRDISGAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLV
EALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFE
QGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVL
PFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS
GIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLGQGRAAD
FNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESR
TLITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGG
VERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLE
PVGISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQP
TFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQL
DEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1626lysS-100% (1097)lysyl-tRNA synthetase
M. ulcerans Agy99MUL_4181lysSe-11846.08% (497) lysyl-tRNA synthetase
M. ulcerans Agy99MUL_1600-9e-2525.94% (397) hypothetical protein MUL_1600

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1667clysS0.085.66% (1102) lysyl-tRNA synthetase
M. gilvum PYR-GCKMflv_3544lysS0.074.16% (1099) lysyl-tRNA synthetase
M. tuberculosis H37RvRv1640clysS0.085.75% (1102) lysyl-tRNA synthetase
M. leprae Br4923MLBr_01393lysS0.082.12% (1040) lysyl-tRNA synthetase
M. abscessus ATCC 19977MAB_2319clysS0.066.36% (1091) lysyl-tRNA synthetase
M. marinum MMMAR_2447lysS0.099.09% (1097) lysyl-tRNA synthetase 2 LysX
M. avium 104MAV_3128lysS0.084.48% (1076) lysyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_3796lysS0.076.86% (1089) lysyl-tRNA synthetase
M. thermoresistible (build 8)TH_2348lysS1e-11545.75% (494) LYSYL-TRNA SYNTHETASE 1 LYSS (LYSINE--TRNA LIGASE 1) (LYSRS 1)
M. vanbaalenii PYR-1Mvan_3330lysS0.076.37% (1096) lysyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3544|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3330|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3796|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1626|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2447|M.marinum_M               --------------------------------------------------
Mb1667c|M.bovis_AF2122/97           MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG
Rv1640c|M.tuberculosis_H37Rv        MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG
MLBr_01393|M.leprae_Br4923          --------------------------------------------------
MAV_3128|M.avium_104                --------------------------------------------------
MAB_2319c|M.abscessus_ATCC_199      ---------------------------------------MTSIKPAVEPP
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          ------------MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASV
Mvan_3330|M.vanbaalenii_PYR-1       ------------MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASV
MSMEG_3796|M.smegmatis_MC2_155      --------------------------MAWVPAAAGWTVGVIATLSLIASV
MUL_1626|M.ulcerans_Agy99           ------------------MQSRHISRYDWVPAAAGWAVGVIATLSLLASI
MMAR_2447|M.marinum_M               ------------------MQGRHISRYDWVPAAAGWAVGVIATLSLLASI
Mb1667c|M.bovis_AF2122/97           ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV
Rv1640c|M.tuberculosis_H37Rv        ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV
MLBr_01393|M.leprae_Br4923          --------------------------------------------------
MAV_3128|M.avium_104                ---------------------------------------MIATVSLLGSV
MAB_2319c|M.abscessus_ATCC_199      APDHPAVTALPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSI
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          SPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI
Mvan_3330|M.vanbaalenii_PYR-1       SPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI
MSMEG_3796|M.smegmatis_MC2_155      SPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWV
MUL_1626|M.ulcerans_Agy99           SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL
MMAR_2447|M.marinum_M               SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL
Mb1667c|M.bovis_AF2122/97           SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV
Rv1640c|M.tuberculosis_H37Rv        SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV
MLBr_01393|M.leprae_Br4923          -------------------------------MLALLAAALTTRKRIAWLL
MAV_3128|M.avium_104                SPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLL
MAB_2319c|M.abscessus_ATCC_199      SPFIRMVTKLPREFVDEYLFGWPDGSLSWAFVLSLLAAALAVRKSIAWWV
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          LTGYMVAAAVWNVTGLLDG-DRWFEDVGEIIGLGFHLAAIASLLLARREF
Mvan_3330|M.vanbaalenii_PYR-1       LVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEF
MSMEG_3796|M.smegmatis_MC2_155      LVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEF
MUL_1626|M.ulcerans_Agy99           LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQF
MMAR_2447|M.marinum_M               LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQF
Mb1667c|M.bovis_AF2122/97           LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF
Rv1640c|M.tuberculosis_H37Rv        LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF
MLBr_01393|M.leprae_Br4923          LLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREF
MAV_3128|M.avium_104                LLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREF
MAB_2319c|M.abscessus_ATCC_199      LLIDLLGRSALNVGGFIEH-----RDTTELIGLVVHGAFILLLLLARKEF
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          WARVRPGALVKAAVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNR
Mvan_3330|M.vanbaalenii_PYR-1       WARVRRGALLKAAATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNR
MSMEG_3796|M.smegmatis_MC2_155      WAKVRRGALLKSAAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNR
MUL_1626|M.ulcerans_Agy99           WTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANR
MMAR_2447|M.marinum_M               WAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANR
Mb1667c|M.bovis_AF2122/97           WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR
Rv1640c|M.tuberculosis_H37Rv        WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR
MLBr_01393|M.leprae_Br4923          WAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANR
MAV_3128|M.avium_104                WAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNR
MAB_2319c|M.abscessus_ATCC_199      YAKVRRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNR
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          VGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALT
Mvan_3330|M.vanbaalenii_PYR-1       VSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALT
MSMEG_3796|M.smegmatis_MC2_155      VSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALT
MUL_1626|M.ulcerans_Agy99           VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT
MMAR_2447|M.marinum_M               VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT
Mb1667c|M.bovis_AF2122/97           VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT
Rv1640c|M.tuberculosis_H37Rv        VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT
MLBr_01393|M.leprae_Br4923          VVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALT
MAV_3128|M.avium_104                VVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALT
MAB_2319c|M.abscessus_ATCC_199      VAGFSIASHRDFDGLPPHFLNWLFGLFGALALIAAAIVLFRSQRAVNALT
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVC
Mvan_3330|M.vanbaalenii_PYR-1       GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVC
MSMEG_3796|M.smegmatis_MC2_155      GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVC
MUL_1626|M.ulcerans_Agy99           GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC
MMAR_2447|M.marinum_M               GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC
Mb1667c|M.bovis_AF2122/97           GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC
Rv1640c|M.tuberculosis_H37Rv        GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC
MLBr_01393|M.leprae_Br4923          GEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVC
MAV_3128|M.avium_104                GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVC
MAB_2319c|M.abscessus_ATCC_199      GDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVC
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          LASGDPVGDPKAWPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLH
Mvan_3330|M.vanbaalenii_PYR-1       LASGDPVGDPRSWPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLN
MSMEG_3796|M.smegmatis_MC2_155      LASGDPVGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLN
MUL_1626|M.ulcerans_Agy99           LASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN
MMAR_2447|M.marinum_M               LASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN
Mb1667c|M.bovis_AF2122/97           LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT
Rv1640c|M.tuberculosis_H37Rv        LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT
MLBr_01393|M.leprae_Br4923          LASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFN
MAV_3128|M.avium_104                LASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLN
MAB_2319c|M.abscessus_ATCC_199      LVSADPIGDKSAWGQAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLN
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          ALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPD
Mvan_3330|M.vanbaalenii_PYR-1       ALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPAD
MSMEG_3796|M.smegmatis_MC2_155      ALQLGDEAILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPE
MUL_1626|M.ulcerans_Agy99           ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGA
MMAR_2447|M.marinum_M               ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDA
Mb1667c|M.bovis_AF2122/97           ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED
Rv1640c|M.tuberculosis_H37Rv        ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED
MLBr_01393|M.leprae_Br4923          AIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISAN
MAV_3128|M.avium_104                ALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPE
MAB_2319c|M.abscessus_ATCC_199      ALELGDEAILYPRSFSISGPHMATVRQAVNRARRSGLSVRIRRHRELSAE
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          EMAEVIAHADAWRDTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVA
Mvan_3330|M.vanbaalenii_PYR-1       EMAAVIERADAWRDTDDERGFSMALGRLGDPADGDCLLVEAVQ-ADQVVA
MSMEG_3796|M.smegmatis_MC2_155      EMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQ-GDEVVA
MUL_1626|M.ulcerans_Agy99           EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA
MMAR_2447|M.marinum_M               EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA
Mb1667c|M.bovis_AF2122/97           EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA
Rv1640c|M.tuberculosis_H37Rv        EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA
MLBr_01393|M.leprae_Br4923          EMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVA
MAV_3128|M.avium_104                AMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVA
MAB_2319c|M.abscessus_ATCC_199      ETKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVA
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          MLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLN
Mvan_3330|M.vanbaalenii_PYR-1       MLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLN
MSMEG_3796|M.smegmatis_MC2_155      MLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLN
MUL_1626|M.ulcerans_Agy99           MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN
MMAR_2447|M.marinum_M               MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN
Mb1667c|M.bovis_AF2122/97           MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN
Rv1640c|M.tuberculosis_H37Rv        MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN
MLBr_01393|M.leprae_Br4923          ILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLN
MAV_3128|M.avium_104                MLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLN
MAB_2319c|M.abscessus_ATCC_199      MLSLVPWGTNGVSLELMRRSRQSPNGTIEFMVTELLTRAEGMGITRVSLN
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW
Mvan_3330|M.vanbaalenii_PYR-1       FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW
MSMEG_3796|M.smegmatis_MC2_155      FAMFRSAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEW
MUL_1626|M.ulcerans_Agy99           FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW
MMAR_2447|M.marinum_M               FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW
Mb1667c|M.bovis_AF2122/97           FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW
Rv1640c|M.tuberculosis_H37Rv        FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW
MLBr_01393|M.leprae_Br4923          FTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDW
MAV_3128|M.avium_104                FAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDW
MAB_2319c|M.abscessus_ATCC_199      FVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEW
TH_2348|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3544|M.gilvum_PYR-GCK          VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDL
Mvan_3330|M.vanbaalenii_PYR-1       VPRYACYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTL
MSMEG_3796|M.smegmatis_MC2_155      VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ-HTGEHIAAPDTL
MUL_1626|M.ulcerans_Agy99           VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL
MMAR_2447|M.marinum_M               VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL
Mb1667c|M.bovis_AF2122/97           VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL
Rv1640c|M.tuberculosis_H37Rv        VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL
MLBr_01393|M.leprae_Br4923          VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRV-HTGHHPAVPARL
MAV_3128|M.avium_104                VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKV-HTGHHPAVPARL
MAB_2319c|M.abscessus_ATCC_199      VPRFACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAI
TH_2348|M.thermoresistible__bu      --------------------------------------------VTPPES
                                                                                ..*   

Mflv_3544|M.gilvum_PYR-GCK          IATGRLHSDGTAPDRIGPVGDGADDDAA--PRLPEQVRVRMAKLSALQDR
Mvan_3330|M.vanbaalenii_PYR-1       VATGLLHSDGTAPDGMGLQADLADDDQ---PRLPEQVRVRMAKLKALQAQ
MSMEG_3796|M.smegmatis_MC2_155      VQSGRLHRDGSAPDVTGLQGELPDADDE--PRLPEQVRVRMAKLKALQGN
MUL_1626|M.ulcerans_Agy99           AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS
MMAR_2447|M.marinum_M               AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS
Mb1667c|M.bovis_AF2122/97           AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS
Rv1640c|M.tuberculosis_H37Rv        AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS
MLBr_01393|M.leprae_Br4923          AESGLLHHDGSTPDVSGLQTA-DVDLEVANSRIPEQVRVRLAKLKTLQLN
MAV_3128|M.avium_104                AQSGLLHHDGSAPDVSGLRPE-RTDAEEARSRLPEQVRVRLAKLKVLQRN
MAB_2319c|M.abscessus_ATCC_199      VATGLLHHDGSTPELLPQTAP--------QQRVPEQVKVRLGKLAALQEK
TH_2348|M.thermoresistible__bu      VDP----------------------------DLPEQFRIRQAKRADLLAQ
                                      .                             :***.::*  *   *   

Mflv_3544|M.gilvum_PYR-GCK          GVDAYPVGSPPSHTIAEA--------IAAEEGTEVTVSGRVLRARDYGGV
Mvan_3330|M.vanbaalenii_PYR-1       GVDAYPVANPPSHTVAQA--------LAAEDGADVAVAGRVLRSRDYGGV
MSMEG_3796|M.smegmatis_MC2_155      GVDAYPVGQPPSHTVAQA--------LGATDGETLSVAGRVMRIRDYGGV
MUL_1626|M.ulcerans_Agy99           GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV
MMAR_2447|M.marinum_M               GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV
Mb1667c|M.bovis_AF2122/97           GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV
Rv1640c|M.tuberculosis_H37Rv        GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV
MLBr_01393|M.leprae_Br4923          GIDAYPVGHPPSHTVAQA--------LDADDEGTVSISGRILRIRDYGGV
MAV_3128|M.avium_104                GVDAYPVGCPPSHTVAQA--------LDADDQQDITVAGRILRIRDFGGV
MAB_2319c|M.abscessus_ATCC_199      GIDTYPVGSPPSHTVAEA--------LAAPDGSEVVISGRLLRIRDYGGV
TH_2348|M.thermoresistible__bu      GRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKL
                                    * :.:**  * :**: :         : *     : ::**::  *: * :

Mflv_3544|M.gilvum_PYR-GCK          LFGQLRDWSA-ETQVALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTR
Mvan_3330|M.vanbaalenii_PYR-1       LFAQLRDWSG-ETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSR
MSMEG_3796|M.smegmatis_MC2_155      LFAQLRDWSG-EVQLLLDNAALTEGETADFTATIDLGDLVEVTGSMGFSR
MUL_1626|M.ulcerans_Agy99           LFAHLRDWSG-EIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSK
MMAR_2447|M.marinum_M               LFAHLRDWSG-EIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSK
Mb1667c|M.bovis_AF2122/97           LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK
Rv1640c|M.tuberculosis_H37Rv        LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK
MLBr_01393|M.leprae_Br4923          LFAHVRDWSG-EIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSK
MAV_3128|M.avium_104                LFAQLRDWSG-EMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSK
MAB_2319c|M.abscessus_ATCC_199      LFAQLRDWSA-EVQLLIDDPRLH----EEFTAAVDLGDLVEASGVMGQSN
TH_2348|M.thermoresistible__bu      CFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSK
                                     *. ::: .. : *  :.   :      ::.   *:**::   * :  :.

Mflv_3544|M.gilvum_PYR-GCK          SGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE
Mvan_3330|M.vanbaalenii_PYR-1       SGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE
MSMEG_3796|M.smegmatis_MC2_155      NGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARD
MUL_1626|M.ulcerans_Agy99           TGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRT
MMAR_2447|M.marinum_M               TGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRA
Mb1667c|M.bovis_AF2122/97           TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA
Rv1640c|M.tuberculosis_H37Rv        TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA
MLBr_01393|M.leprae_Br4923          NGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRN
MAV_3128|M.avium_104                KGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRE
MAB_2319c|M.abscessus_ATCC_199      NGTRSVLVESWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEARE
TH_2348|M.thermoresistible__bu      RGELSVLADSWQMAAKALRPLPVAHKEMSE-ESRVRQRYVDLIVRDQARK
                                     *  *::.  *:: .*.*:***   : : : *:*** **:** :. ::* 

Mflv_3544|M.gilvum_PYR-GCK          LIKARSAILHAIRETLVGKGFLEVETPILQQIHGGANARPFLTHINAYDL
Mvan_3330|M.vanbaalenii_PYR-1       LIRARSAVLHAIRETLVAKDFLEVETPILQQIHGGANARPFLTHINAYDL
MSMEG_3796|M.smegmatis_MC2_155      LIRARSGALHAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDL
MUL_1626|M.ulcerans_Agy99           LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM
MMAR_2447|M.marinum_M               LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM
Mb1667c|M.bovis_AF2122/97           LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM
Rv1640c|M.tuberculosis_H37Rv        LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM
MLBr_01393|M.leprae_Br4923          LIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDM
MAV_3128|M.avium_104                LIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDM
MAB_2319c|M.abscessus_ATCC_199      QIAARSAIITSLRNTLLAQGFLEVETPILQQVHGGANARPFLTHINAYNL
TH_2348|M.thermoresistible__bu      VARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDT
                                        *   : ::*. *  :.*:*****:** : *** **** *: *: . 

Mflv_3544|M.gilvum_PYR-GCK          DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Mvan_3330|M.vanbaalenii_PYR-1       DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MSMEG_3796|M.smegmatis_MC2_155      DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MUL_1626|M.ulcerans_Agy99           DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MMAR_2447|M.marinum_M               DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Mb1667c|M.bovis_AF2122/97           DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Rv1640c|M.tuberculosis_H37Rv        DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MLBr_01393|M.leprae_Br4923          DLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MAV_3128|M.avium_104                DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MAB_2319c|M.abscessus_ATCC_199      DLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTLLEAYQ
TH_2348|M.thermoresistible__bu      ELYLRIAPELFLKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQ
                                    :*:*******:***  :**.*:****.*.*****.* :*.***.:**:**

Mflv_3544|M.gilvum_PYR-GCK          AHADYTVWIDGCRELIQNAAMAANGSHVFFRP----RED---GVLEPVDI
Mvan_3330|M.vanbaalenii_PYR-1       AHADYHVWIDGCRELIQNAAQAANGAQVFMRP----RAD---GVLEPVDI
MSMEG_3796|M.smegmatis_MC2_155      AHADYNVWIDGCRELIQNAAQAANGAQVFLRP----RPNDPAGTLEPVDI
MUL_1626|M.ulcerans_Agy99           AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVGI
MMAR_2447|M.marinum_M               AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVDI
Mb1667c|M.bovis_AF2122/97           AHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI
Rv1640c|M.tuberculosis_H37Rv        AHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI
MLBr_01393|M.leprae_Br4923          AHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIE-GASGTANHLEPIDI
MAV_3128|M.avium_104                AHADYRVWIDGCRELIQNAAQAAHGEQTVLRP-------GADGRLQPVDI
MAB_2319c|M.abscessus_ATCC_199      AHADYVTWAQTTQRLIQNAAKAAHGAEVVMRP-------GADGRLAPVDI
TH_2348|M.thermoresistible__bu      AYGTYDDSAVVTRELIQEVADEAIGTRQVPLP-----------DGTVYDL
                                    *:. *       :.***:.*  * *      *                .:

Mflv_3544|M.gilvum_PYR-GCK          SGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCD--KAGIPYLTHWDAG
Mvan_3330|M.vanbaalenii_PYR-1       SGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCD--RAGIPYLTHWDAG
MSMEG_3796|M.smegmatis_MC2_155      SGQWAVKTVHDAVSEAIGEHITPETELGELRRLCD--SAGIPYLTHWDAG
MUL_1626|M.ulcerans_Agy99           SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG
MMAR_2447|M.marinum_M               SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG
Mb1667c|M.bovis_AF2122/97           SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG
Rv1640c|M.tuberculosis_H37Rv        SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG
MLBr_01393|M.leprae_Br4923          SGVWPVKTVYEAVSEALGECVDTSTELATLRKLSD--AAHIPYWPHWDTG
MAV_3128|M.avium_104                SGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSD--AARIPYRAHWDAG
MAB_2319c|M.abscessus_ATCC_199      GGEWPIVPVHEAVSRALGEEVNAATEVPTLQRFCQ--SAEVQFNPRWDAG
TH_2348|M.thermoresistible__bu      DGEWESIQMYPSLSEALGEEITPDTPAETLWAIADRLGLDIPRDRGYGHG
                                    .* *    :: ::*.*:** :   *    *  :.:     :     :. *

Mflv_3544|M.gilvum_PYR-GCK          AVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
Mvan_3330|M.vanbaalenii_PYR-1       AVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
MSMEG_3796|M.smegmatis_MC2_155      AVVLEMYEHLVEDRTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
MUL_1626|M.ulcerans_Agy99           AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW
MMAR_2447|M.marinum_M               AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW
Mb1667c|M.bovis_AF2122/97           AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW
Rv1640c|M.tuberculosis_H37Rv        AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW
MLBr_01393|M.leprae_Br4923          AVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAW
MAV_3128|M.avium_104                AVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAW
MAB_2319c|M.abscessus_ATCC_199      HLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSIAGLAERWDLVAW
TH_2348|M.thermoresistible__bu      KLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVR
                                     :* :::*: *  :   ***  ***...:****.***  *::*:*** . 

Mflv_3544|M.gilvum_PYR-GCK          GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
Mvan_3330|M.vanbaalenii_PYR-1       GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MSMEG_3796|M.smegmatis_MC2_155      GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MUL_1626|M.ulcerans_Agy99           GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM
MMAR_2447|M.marinum_M               GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM
Mb1667c|M.bovis_AF2122/97           GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
Rv1640c|M.tuberculosis_H37Rv        GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MLBr_01393|M.leprae_Br4923          GIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAM
MAV_3128|M.avium_104                GVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MAB_2319c|M.abscessus_ATCC_199      GVELGTAYTELTDPVEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAM
TH_2348|M.thermoresistible__bu      RIELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGM
                                     :**.*.*:*****: ** *:  *:  *..*: *** ****** *:**.*

Mflv_3544|M.gilvum_PYR-GCK          PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR
Mvan_3330|M.vanbaalenii_PYR-1       PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR
MSMEG_3796|M.smegmatis_MC2_155      PPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR
MUL_1626|M.ulcerans_Agy99           PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
MMAR_2447|M.marinum_M               PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
Mb1667c|M.bovis_AF2122/97           PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH
Rv1640c|M.tuberculosis_H37Rv        PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH
MLBr_01393|M.leprae_Br4923          PPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH
MAV_3128|M.avium_104                PPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH
MAB_2319c|M.abscessus_ATCC_199      APTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR
TH_2348|M.thermoresistible__bu      PPSTGTGMGIDRLMMTLTGLSIRETVLFPIVKPR
                                    .*: * ***:**::* :** *****: **:.**: