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QGRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAA LAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQFWAKVRRGAL FKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGA LALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGV CLASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSG PDMRGVRQAVTRARRAGLTVRIRRHRDISDAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLV EALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFE QGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVL PFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS GIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLEQGRAAD FNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESR ALITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGG VERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLE PVDISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQP TFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQL DEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2447 | lysS | - | 100% (1097) | lysyl-tRNA synthetase 2 LysX |
M. marinum M | MMAR_5102 | lysS | e-118 | 46.56% (494) | lysyl-tRNA synthetase 1 LysS |
M. marinum M | MMAR_2422 | - | 1e-26 | 26.45% (397) | hypothetical protein MMAR_2422 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1667c | lysS | 0.0 | 86.52% (1098) | lysyl-tRNA synthetase |
M. gilvum PYR-GCK | Mflv_3544 | lysS | 0.0 | 74.93% (1093) | lysyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv1640c | lysS | 0.0 | 86.61% (1098) | lysyl-tRNA synthetase |
M. leprae Br4923 | MLBr_01393 | lysS | 0.0 | 82.79% (1040) | lysyl-tRNA synthetase |
M. abscessus ATCC 19977 | MAB_2319c | lysS | 0.0 | 66.73% (1091) | lysyl-tRNA synthetase |
M. avium 104 | MAV_3128 | lysS | 0.0 | 85.13% (1076) | lysyl-tRNA synthetase |
M. smegmatis MC2 155 | MSMEG_3796 | lysS | 0.0 | 77.32% (1089) | lysyl-tRNA synthetase |
M. thermoresistible (build 8) | TH_2348 | lysS | 1e-115 | 45.95% (494) | LYSYL-TRNA SYNTHETASE 1 LYSS (LYSINE--TRNA LIGASE 1) (LYSRS 1) |
M. ulcerans Agy99 | MUL_1626 | lysS | 0.0 | 99.09% (1097) | lysyl-tRNA synthetase |
M. vanbaalenii PYR-1 | Mvan_3330 | lysS | 0.0 | 76.92% (1096) | lysyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3544|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3330|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3796|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_2447|M.marinum_M -------------------------------------------------- MUL_1626|M.ulcerans_Agy99 -------------------------------------------------- Mb1667c|M.bovis_AF2122/97 MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG Rv1640c|M.tuberculosis_H37Rv MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG MLBr_01393|M.leprae_Br4923 -------------------------------------------------- MAV_3128|M.avium_104 -------------------------------------------------- MAB_2319c|M.abscessus_ATCC_199 ---------------------------------------MTSIKPAVEPP TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK ------------MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASV Mvan_3330|M.vanbaalenii_PYR-1 ------------MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASV MSMEG_3796|M.smegmatis_MC2_155 --------------------------MAWVPAAAGWTVGVIATLSLIASV MMAR_2447|M.marinum_M ------------------MQGRHISRYDWVPAAAGWAVGVIATLSLLASI MUL_1626|M.ulcerans_Agy99 ------------------MQSRHISRYDWVPAAAGWAVGVIATLSLLASI Mb1667c|M.bovis_AF2122/97 ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV Rv1640c|M.tuberculosis_H37Rv ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV MLBr_01393|M.leprae_Br4923 -------------------------------------------------- MAV_3128|M.avium_104 ---------------------------------------MIATVSLLGSV MAB_2319c|M.abscessus_ATCC_199 APDHPAVTALPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSI TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK SPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI Mvan_3330|M.vanbaalenii_PYR-1 SPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI MSMEG_3796|M.smegmatis_MC2_155 SPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWV MMAR_2447|M.marinum_M SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL MUL_1626|M.ulcerans_Agy99 SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL Mb1667c|M.bovis_AF2122/97 SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV Rv1640c|M.tuberculosis_H37Rv SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV MLBr_01393|M.leprae_Br4923 -------------------------------MLALLAAALTTRKRIAWLL MAV_3128|M.avium_104 SPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLL MAB_2319c|M.abscessus_ATCC_199 SPFIRMVTKLPREFVDEYLFGWPDGSLSWAFVLSLLAAALAVRKSIAWWV TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK LTGYMVAAAVWNVTGLLDG-DRWFEDVGEIIGLGFHLAAIASLLLARREF Mvan_3330|M.vanbaalenii_PYR-1 LVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEF MSMEG_3796|M.smegmatis_MC2_155 LVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEF MMAR_2447|M.marinum_M LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQF MUL_1626|M.ulcerans_Agy99 LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQF Mb1667c|M.bovis_AF2122/97 LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF Rv1640c|M.tuberculosis_H37Rv LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF MLBr_01393|M.leprae_Br4923 LLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREF MAV_3128|M.avium_104 LLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREF MAB_2319c|M.abscessus_ATCC_199 LLIDLLGRSALNVGGFIEH-----RDTTELIGLVVHGAFILLLLLARKEF TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK WARVRPGALVKAAVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNR Mvan_3330|M.vanbaalenii_PYR-1 WARVRRGALLKAAATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNR MSMEG_3796|M.smegmatis_MC2_155 WAKVRRGALLKSAAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNR MMAR_2447|M.marinum_M WAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANR MUL_1626|M.ulcerans_Agy99 WTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANR Mb1667c|M.bovis_AF2122/97 WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR Rv1640c|M.tuberculosis_H37Rv WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR MLBr_01393|M.leprae_Br4923 WAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANR MAV_3128|M.avium_104 WAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNR MAB_2319c|M.abscessus_ATCC_199 YAKVRRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNR TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK VGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALT Mvan_3330|M.vanbaalenii_PYR-1 VSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALT MSMEG_3796|M.smegmatis_MC2_155 VSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALT MMAR_2447|M.marinum_M VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT MUL_1626|M.ulcerans_Agy99 VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT Mb1667c|M.bovis_AF2122/97 VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT Rv1640c|M.tuberculosis_H37Rv VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT MLBr_01393|M.leprae_Br4923 VVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALT MAV_3128|M.avium_104 VVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALT MAB_2319c|M.abscessus_ATCC_199 VAGFSIASHRDFDGLPPHFLNWLFGLFGALALIAAAIVLFRSQRAVNALT TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVC Mvan_3330|M.vanbaalenii_PYR-1 GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVC MSMEG_3796|M.smegmatis_MC2_155 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVC MMAR_2447|M.marinum_M GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC MUL_1626|M.ulcerans_Agy99 GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC Mb1667c|M.bovis_AF2122/97 GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC Rv1640c|M.tuberculosis_H37Rv GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC MLBr_01393|M.leprae_Br4923 GEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVC MAV_3128|M.avium_104 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVC MAB_2319c|M.abscessus_ATCC_199 GDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVC TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK LASGDPVGDPKAWPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLH Mvan_3330|M.vanbaalenii_PYR-1 LASGDPVGDPRSWPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLN MSMEG_3796|M.smegmatis_MC2_155 LASGDPVGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLN MMAR_2447|M.marinum_M LASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN MUL_1626|M.ulcerans_Agy99 LASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN Mb1667c|M.bovis_AF2122/97 LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT Rv1640c|M.tuberculosis_H37Rv LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT MLBr_01393|M.leprae_Br4923 LASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFN MAV_3128|M.avium_104 LASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLN MAB_2319c|M.abscessus_ATCC_199 LVSADPIGDKSAWGQAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLN TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK ALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPD Mvan_3330|M.vanbaalenii_PYR-1 ALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPAD MSMEG_3796|M.smegmatis_MC2_155 ALQLGDEAILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPE MMAR_2447|M.marinum_M ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDA MUL_1626|M.ulcerans_Agy99 ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGA Mb1667c|M.bovis_AF2122/97 ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED Rv1640c|M.tuberculosis_H37Rv ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED MLBr_01393|M.leprae_Br4923 AIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISAN MAV_3128|M.avium_104 ALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPE MAB_2319c|M.abscessus_ATCC_199 ALELGDEAILYPRSFSISGPHMATVRQAVNRARRSGLSVRIRRHRELSAE TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK EMAEVIAHADAWRDTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVA Mvan_3330|M.vanbaalenii_PYR-1 EMAAVIERADAWRDTDDERGFSMALGRLGDPADGDCLLVEAVQ-ADQVVA MSMEG_3796|M.smegmatis_MC2_155 EMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQ-GDEVVA MMAR_2447|M.marinum_M EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA MUL_1626|M.ulcerans_Agy99 EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA Mb1667c|M.bovis_AF2122/97 EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA Rv1640c|M.tuberculosis_H37Rv EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA MLBr_01393|M.leprae_Br4923 EMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVA MAV_3128|M.avium_104 AMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVA MAB_2319c|M.abscessus_ATCC_199 ETKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVA TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK MLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLN Mvan_3330|M.vanbaalenii_PYR-1 MLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLN MSMEG_3796|M.smegmatis_MC2_155 MLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLN MMAR_2447|M.marinum_M MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN MUL_1626|M.ulcerans_Agy99 MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN Mb1667c|M.bovis_AF2122/97 MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN Rv1640c|M.tuberculosis_H37Rv MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN MLBr_01393|M.leprae_Br4923 ILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLN MAV_3128|M.avium_104 MLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLN MAB_2319c|M.abscessus_ATCC_199 MLSLVPWGTNGVSLELMRRSRQSPNGTIEFMVTELLTRAEGMGITRVSLN TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW Mvan_3330|M.vanbaalenii_PYR-1 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW MSMEG_3796|M.smegmatis_MC2_155 FAMFRSAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEW MMAR_2447|M.marinum_M FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW MUL_1626|M.ulcerans_Agy99 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW Mb1667c|M.bovis_AF2122/97 FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW Rv1640c|M.tuberculosis_H37Rv FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW MLBr_01393|M.leprae_Br4923 FTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDW MAV_3128|M.avium_104 FAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDW MAB_2319c|M.abscessus_ATCC_199 FVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEW TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDL Mvan_3330|M.vanbaalenii_PYR-1 VPRYACYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTL MSMEG_3796|M.smegmatis_MC2_155 VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ-HTGEHIAAPDTL MMAR_2447|M.marinum_M VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL MUL_1626|M.ulcerans_Agy99 VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL Mb1667c|M.bovis_AF2122/97 VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL Rv1640c|M.tuberculosis_H37Rv VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL MLBr_01393|M.leprae_Br4923 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRV-HTGHHPAVPARL MAV_3128|M.avium_104 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKV-HTGHHPAVPARL MAB_2319c|M.abscessus_ATCC_199 VPRFACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAI TH_2348|M.thermoresistible__bu --------------------------------------------VTPPES ..* Mflv_3544|M.gilvum_PYR-GCK IATGRLHSDGTAPDRIGPVGDGADDDAA--PRLPEQVRVRMAKLSALQDR Mvan_3330|M.vanbaalenii_PYR-1 VATGLLHSDGTAPDGMGLQADLADDDQ---PRLPEQVRVRMAKLKALQAQ MSMEG_3796|M.smegmatis_MC2_155 VQSGRLHRDGSAPDVTGLQGELPDADDE--PRLPEQVRVRMAKLKALQGN MMAR_2447|M.marinum_M AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS MUL_1626|M.ulcerans_Agy99 AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS Mb1667c|M.bovis_AF2122/97 AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS Rv1640c|M.tuberculosis_H37Rv AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS MLBr_01393|M.leprae_Br4923 AESGLLHHDGSTPDVSGLQTA-DVDLEVANSRIPEQVRVRLAKLKTLQLN MAV_3128|M.avium_104 AQSGLLHHDGSAPDVSGLRPE-RTDAEEARSRLPEQVRVRLAKLKVLQRN MAB_2319c|M.abscessus_ATCC_199 VATGLLHHDGSTPELLPQTAP--------QQRVPEQVKVRLGKLAALQEK TH_2348|M.thermoresistible__bu VDP----------------------------DLPEQFRIRQAKRADLLAQ . :***.::* * * Mflv_3544|M.gilvum_PYR-GCK GVDAYPVGSPPSHTIAEA--------IAAEEGTEVTVSGRVLRARDYGGV Mvan_3330|M.vanbaalenii_PYR-1 GVDAYPVANPPSHTVAQA--------LAAEDGADVAVAGRVLRSRDYGGV MSMEG_3796|M.smegmatis_MC2_155 GVDAYPVGQPPSHTVAQA--------LGATDGETLSVAGRVMRIRDYGGV MMAR_2447|M.marinum_M GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV MUL_1626|M.ulcerans_Agy99 GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV Mb1667c|M.bovis_AF2122/97 GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV Rv1640c|M.tuberculosis_H37Rv GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV MLBr_01393|M.leprae_Br4923 GIDAYPVGHPPSHTVAQA--------LDADDEGTVSISGRILRIRDYGGV MAV_3128|M.avium_104 GVDAYPVGCPPSHTVAQA--------LDADDQQDITVAGRILRIRDFGGV MAB_2319c|M.abscessus_ATCC_199 GIDTYPVGSPPSHTVAEA--------LAAPDGSEVVISGRLLRIRDYGGV TH_2348|M.thermoresistible__bu GRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKL * :.:** * :**: : : * : ::**:: *: * : Mflv_3544|M.gilvum_PYR-GCK LFGQLRDWSA-ETQVALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTR Mvan_3330|M.vanbaalenii_PYR-1 LFAQLRDWSG-ETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSR MSMEG_3796|M.smegmatis_MC2_155 LFAQLRDWSG-EVQLLLDNAALTEGETADFTATIDLGDLVEVTGSMGFSR MMAR_2447|M.marinum_M LFAHLRDWSG-EIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSK MUL_1626|M.ulcerans_Agy99 LFAHLRDWSG-EIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSK Mb1667c|M.bovis_AF2122/97 LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK Rv1640c|M.tuberculosis_H37Rv LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK MLBr_01393|M.leprae_Br4923 LFAHVRDWSG-EIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSK MAV_3128|M.avium_104 LFAQLRDWSG-EMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSK MAB_2319c|M.abscessus_ATCC_199 LFAQLRDWSA-EVQLLIDDPRLH----EEFTAAVDLGDLVEASGVMGQSN TH_2348|M.thermoresistible__bu CFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSK *. ::: .. : * :. : ::. *:**:: * : :. Mflv_3544|M.gilvum_PYR-GCK SGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE Mvan_3330|M.vanbaalenii_PYR-1 SGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE MSMEG_3796|M.smegmatis_MC2_155 NGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARD MMAR_2447|M.marinum_M TGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRA MUL_1626|M.ulcerans_Agy99 TGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRT Mb1667c|M.bovis_AF2122/97 TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA Rv1640c|M.tuberculosis_H37Rv TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA MLBr_01393|M.leprae_Br4923 NGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRN MAV_3128|M.avium_104 KGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRE MAB_2319c|M.abscessus_ATCC_199 NGTRSVLVESWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEARE TH_2348|M.thermoresistible__bu RGELSVLADSWQMAAKALRPLPVAHKEMSE-ESRVRQRYVDLIVRDQARK * *::. *:: .*.*:*** : : : *:*** **:** :. ::* Mflv_3544|M.gilvum_PYR-GCK LIKARSAILHAIRETLVGKGFLEVETPILQQIHGGANARPFLTHINAYDL Mvan_3330|M.vanbaalenii_PYR-1 LIRARSAVLHAIRETLVAKDFLEVETPILQQIHGGANARPFLTHINAYDL MSMEG_3796|M.smegmatis_MC2_155 LIRARSGALHAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDL MMAR_2447|M.marinum_M LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM MUL_1626|M.ulcerans_Agy99 LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM Mb1667c|M.bovis_AF2122/97 LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM Rv1640c|M.tuberculosis_H37Rv LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM MLBr_01393|M.leprae_Br4923 LIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDM MAV_3128|M.avium_104 LIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDM MAB_2319c|M.abscessus_ATCC_199 QIAARSAIITSLRNTLLAQGFLEVETPILQQVHGGANARPFLTHINAYNL TH_2348|M.thermoresistible__bu VARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDT * : ::*. * :.*:*****:** : *** **** *: *: . Mflv_3544|M.gilvum_PYR-GCK DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Mvan_3330|M.vanbaalenii_PYR-1 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MSMEG_3796|M.smegmatis_MC2_155 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MMAR_2447|M.marinum_M DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MUL_1626|M.ulcerans_Agy99 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Mb1667c|M.bovis_AF2122/97 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Rv1640c|M.tuberculosis_H37Rv DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MLBr_01393|M.leprae_Br4923 DLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MAV_3128|M.avium_104 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MAB_2319c|M.abscessus_ATCC_199 DLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTLLEAYQ TH_2348|M.thermoresistible__bu ELYLRIAPELFLKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQ :*:*******:*** :**.*:****.*.*****.* :*.***.:**:** Mflv_3544|M.gilvum_PYR-GCK AHADYTVWIDGCRELIQNAAMAANGSHVFFRP----RED---GVLEPVDI Mvan_3330|M.vanbaalenii_PYR-1 AHADYHVWIDGCRELIQNAAQAANGAQVFMRP----RAD---GVLEPVDI MSMEG_3796|M.smegmatis_MC2_155 AHADYNVWIDGCRELIQNAAQAANGAQVFLRP----RPNDPAGTLEPVDI MMAR_2447|M.marinum_M AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVDI MUL_1626|M.ulcerans_Agy99 AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVGI Mb1667c|M.bovis_AF2122/97 AHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI Rv1640c|M.tuberculosis_H37Rv AHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI MLBr_01393|M.leprae_Br4923 AHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIE-GASGTANHLEPIDI MAV_3128|M.avium_104 AHADYRVWIDGCRELIQNAAQAAHGEQTVLRP-------GADGRLQPVDI MAB_2319c|M.abscessus_ATCC_199 AHADYVTWAQTTQRLIQNAAKAAHGAEVVMRP-------GADGRLAPVDI TH_2348|M.thermoresistible__bu AYGTYDDSAVVTRELIQEVADEAIGTRQVPLP-----------DGTVYDL *:. * :.***:.* * * * .: Mflv_3544|M.gilvum_PYR-GCK SGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCD--KAGIPYLTHWDAG Mvan_3330|M.vanbaalenii_PYR-1 SGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCD--RAGIPYLTHWDAG MSMEG_3796|M.smegmatis_MC2_155 SGQWAVKTVHDAVSEAIGEHITPETELGELRRLCD--SAGIPYLTHWDAG MMAR_2447|M.marinum_M SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG MUL_1626|M.ulcerans_Agy99 SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG Mb1667c|M.bovis_AF2122/97 SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG Rv1640c|M.tuberculosis_H37Rv SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG MLBr_01393|M.leprae_Br4923 SGVWPVKTVYEAVSEALGECVDTSTELATLRKLSD--AAHIPYWPHWDTG MAV_3128|M.avium_104 SGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSD--AARIPYRAHWDAG MAB_2319c|M.abscessus_ATCC_199 GGEWPIVPVHEAVSRALGEEVNAATEVPTLQRFCQ--SAEVQFNPRWDAG TH_2348|M.thermoresistible__bu DGEWESIQMYPSLSEALGEEITPDTPAETLWAIADRLGLDIPRDRGYGHG .* * :: ::*.*:** : * * :.: : :. * Mflv_3544|M.gilvum_PYR-GCK AVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW Mvan_3330|M.vanbaalenii_PYR-1 AVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW MSMEG_3796|M.smegmatis_MC2_155 AVVLEMYEHLVEDRTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW MMAR_2447|M.marinum_M AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW MUL_1626|M.ulcerans_Agy99 AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW Mb1667c|M.bovis_AF2122/97 AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW Rv1640c|M.tuberculosis_H37Rv AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW MLBr_01393|M.leprae_Br4923 AVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAW MAV_3128|M.avium_104 AVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAW MAB_2319c|M.abscessus_ATCC_199 HLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSIAGLAERWDLVAW TH_2348|M.thermoresistible__bu KLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVR :* :::*: * : *** ***...:****.*** *::*:*** . Mflv_3544|M.gilvum_PYR-GCK GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM Mvan_3330|M.vanbaalenii_PYR-1 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MSMEG_3796|M.smegmatis_MC2_155 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MMAR_2447|M.marinum_M GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM MUL_1626|M.ulcerans_Agy99 GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM Mb1667c|M.bovis_AF2122/97 GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM Rv1640c|M.tuberculosis_H37Rv GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MLBr_01393|M.leprae_Br4923 GIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAM MAV_3128|M.avium_104 GVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MAB_2319c|M.abscessus_ATCC_199 GVELGTAYTELTDPVEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAM TH_2348|M.thermoresistible__bu RIELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGM :**.*.*:*****: ** *: *: *..*: *** ****** *:**.* Mflv_3544|M.gilvum_PYR-GCK PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR Mvan_3330|M.vanbaalenii_PYR-1 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR MSMEG_3796|M.smegmatis_MC2_155 PPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR MMAR_2447|M.marinum_M PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH MUL_1626|M.ulcerans_Agy99 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH Mb1667c|M.bovis_AF2122/97 PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH Rv1640c|M.tuberculosis_H37Rv PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH MLBr_01393|M.leprae_Br4923 PPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH MAV_3128|M.avium_104 PPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH MAB_2319c|M.abscessus_ATCC_199 APTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR TH_2348|M.thermoresistible__bu PPSTGTGMGIDRLMMTLTGLSIRETVLFPIVKPR .*: * ***:**::* :** *****: **:.**: