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VIATVSLLGSVSPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLLLLGNMILAA ALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREFWAKVRKGALVKAAAVLVAGDVVGILVSWG LVELFPGTLARQDRLPYVVNRVVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENAL TGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVCLASGDPIGDPRAWPQAVDA WLGLCQTYGWAPGVMGASTQGARTYREAGLNALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTV RIRRHRDISPEAMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVAMLSLVPWGT TGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLNFAMFRSAFEQGAQLGAGPVARLWRGLLLF FSRWWQLETLYRSNMKYQPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKVHTGHHPAVPARL AQSGLLHHDGSAPDVSGLRPERTDAEEARSRLPEQVRVRLAKLKVLQRNGVDAYPVGCPPSHTVAQALDA DDQQDITVAGRILRIRDFGGVLFAQLRDWSGEMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSK KGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRELIAARSEVLRSVRQTLFAKG FIEVETPILQQIHGGATARPFVTHINTYDMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHN PEFTLLEAYQAHADYRVWIDGCRELIQNAAQAAHGEQTVLRPGADGRLQPVDISGIWAVKTVHDAVSEAL GEQVDPGTSLSTLRKLSDAARIPYRAHWDAGAVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRP GVAERWDLVAWGVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMG VDRLVMLITGRSIRETLPFPLAKPH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3128 | lysS | - | 100% (1075) | lysyl-tRNA synthetase |
M. avium 104 | MAV_0554 | lysS | e-118 | 47.47% (495) | lysyl-tRNA synthetase |
M. avium 104 | MAV_3168 | - | 1e-30 | 26.25% (400) | hypothetical protein MAV_3168 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1667c | lysS | 0.0 | 83.56% (1083) | lysyl-tRNA synthetase |
M. gilvum PYR-GCK | Mflv_3544 | lysS | 0.0 | 76.00% (1075) | lysyl-tRNA synthetase |
M. tuberculosis H37Rv | Rv1640c | lysS | 0.0 | 83.66% (1083) | lysyl-tRNA synthetase |
M. leprae Br4923 | MLBr_01393 | lysS | 0.0 | 84.79% (1039) | lysyl-tRNA synthetase |
M. abscessus ATCC 19977 | MAB_2319c | lysS | 0.0 | 67.29% (1073) | lysyl-tRNA synthetase |
M. marinum M | MMAR_2447 | lysS | 0.0 | 85.13% (1076) | lysyl-tRNA synthetase 2 LysX |
M. smegmatis MC2 155 | MSMEG_3796 | lysS | 0.0 | 78.55% (1077) | lysyl-tRNA synthetase |
M. thermoresistible (build 8) | TH_2348 | lysS | 1e-116 | 45.92% (503) | LYSYL-TRNA SYNTHETASE 1 LYSS (LYSINE--TRNA LIGASE 1) (LYSRS 1) |
M. ulcerans Agy99 | MUL_1626 | lysS | 0.0 | 84.48% (1076) | lysyl-tRNA synthetase |
M. vanbaalenii PYR-1 | Mvan_3330 | lysS | 0.0 | 77.86% (1075) | lysyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3544|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3330|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3796|M.smegmatis_MC2_155 -------------------------------------------------- Mb1667c|M.bovis_AF2122/97 MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG Rv1640c|M.tuberculosis_H37Rv MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG MMAR_2447|M.marinum_M -------------------------------------------------- MUL_1626|M.ulcerans_Agy99 -------------------------------------------------- MAV_3128|M.avium_104 -------------------------------------------------- MLBr_01393|M.leprae_Br4923 -------------------------------------------------- MAB_2319c|M.abscessus_ATCC_199 ---------------------------------------MTSIKPAVEPP TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK ------------MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASV Mvan_3330|M.vanbaalenii_PYR-1 ------------MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASV MSMEG_3796|M.smegmatis_MC2_155 --------------------------MAWVPAAAGWTVGVIATLSLIASV Mb1667c|M.bovis_AF2122/97 ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV Rv1640c|M.tuberculosis_H37Rv ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV MMAR_2447|M.marinum_M ------------------MQGRHISRYDWVPAAAGWAVGVIATLSLLASI MUL_1626|M.ulcerans_Agy99 ------------------MQSRHISRYDWVPAAAGWAVGVIATLSLLASI MAV_3128|M.avium_104 ---------------------------------------MIATVSLLGSV MLBr_01393|M.leprae_Br4923 -------------------------------------------------- MAB_2319c|M.abscessus_ATCC_199 APDHPAVTALPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSI TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK SPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI Mvan_3330|M.vanbaalenii_PYR-1 SPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI MSMEG_3796|M.smegmatis_MC2_155 SPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWV Mb1667c|M.bovis_AF2122/97 SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV Rv1640c|M.tuberculosis_H37Rv SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV MMAR_2447|M.marinum_M SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL MUL_1626|M.ulcerans_Agy99 SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL MAV_3128|M.avium_104 SPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLL MLBr_01393|M.leprae_Br4923 -------------------------------MLALLAAALTTRKRIAWLL MAB_2319c|M.abscessus_ATCC_199 SPFIRMVTKLPREFVDEYLFGWPDGSLSWAFVLSLLAAALAVRKSIAWWV TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK LTGYMVAAAVWNVTGLLDG-DRWFEDVGEIIGLGFHLAAIASLLLARREF Mvan_3330|M.vanbaalenii_PYR-1 LVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEF MSMEG_3796|M.smegmatis_MC2_155 LVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEF Mb1667c|M.bovis_AF2122/97 LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF Rv1640c|M.tuberculosis_H37Rv LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF MMAR_2447|M.marinum_M LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQF MUL_1626|M.ulcerans_Agy99 LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQF MAV_3128|M.avium_104 LLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREF MLBr_01393|M.leprae_Br4923 LLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREF MAB_2319c|M.abscessus_ATCC_199 LLIDLLGRSALNVGGFIEH-----RDTTELIGLVVHGAFILLLLLARKEF TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK WARVRPGALVKAAVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNR Mvan_3330|M.vanbaalenii_PYR-1 WARVRRGALLKAAATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNR MSMEG_3796|M.smegmatis_MC2_155 WAKVRRGALLKSAAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNR Mb1667c|M.bovis_AF2122/97 WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR Rv1640c|M.tuberculosis_H37Rv WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR MMAR_2447|M.marinum_M WAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANR MUL_1626|M.ulcerans_Agy99 WTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANR MAV_3128|M.avium_104 WAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNR MLBr_01393|M.leprae_Br4923 WAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANR MAB_2319c|M.abscessus_ATCC_199 YAKVRRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNR TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK VGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALT Mvan_3330|M.vanbaalenii_PYR-1 VSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALT MSMEG_3796|M.smegmatis_MC2_155 VSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALT Mb1667c|M.bovis_AF2122/97 VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT Rv1640c|M.tuberculosis_H37Rv VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT MMAR_2447|M.marinum_M VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT MUL_1626|M.ulcerans_Agy99 VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT MAV_3128|M.avium_104 VVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALT MLBr_01393|M.leprae_Br4923 VVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALT MAB_2319c|M.abscessus_ATCC_199 VAGFSIASHRDFDGLPPHFLNWLFGLFGALALIAAAIVLFRSQRAVNALT TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVC Mvan_3330|M.vanbaalenii_PYR-1 GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVC MSMEG_3796|M.smegmatis_MC2_155 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVC Mb1667c|M.bovis_AF2122/97 GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC Rv1640c|M.tuberculosis_H37Rv GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC MMAR_2447|M.marinum_M GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC MUL_1626|M.ulcerans_Agy99 GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC MAV_3128|M.avium_104 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVC MLBr_01393|M.leprae_Br4923 GEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVC MAB_2319c|M.abscessus_ATCC_199 GDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVC TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK LASGDPVGDPKAWPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLH Mvan_3330|M.vanbaalenii_PYR-1 LASGDPVGDPRSWPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLN MSMEG_3796|M.smegmatis_MC2_155 LASGDPVGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLN Mb1667c|M.bovis_AF2122/97 LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT Rv1640c|M.tuberculosis_H37Rv LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT MMAR_2447|M.marinum_M LASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN MUL_1626|M.ulcerans_Agy99 LASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN MAV_3128|M.avium_104 LASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLN MLBr_01393|M.leprae_Br4923 LASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFN MAB_2319c|M.abscessus_ATCC_199 LVSADPIGDKSAWGQAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLN TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK ALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPD Mvan_3330|M.vanbaalenii_PYR-1 ALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPAD MSMEG_3796|M.smegmatis_MC2_155 ALQLGDEAILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPE Mb1667c|M.bovis_AF2122/97 ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED Rv1640c|M.tuberculosis_H37Rv ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED MMAR_2447|M.marinum_M ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDA MUL_1626|M.ulcerans_Agy99 ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGA MAV_3128|M.avium_104 ALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPE MLBr_01393|M.leprae_Br4923 AIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISAN MAB_2319c|M.abscessus_ATCC_199 ALELGDEAILYPRSFSISGPHMATVRQAVNRARRSGLSVRIRRHRELSAE TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK EMAEVIAHADAWRDTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVA Mvan_3330|M.vanbaalenii_PYR-1 EMAAVIERADAWRDTDDERGFSMALGRLGDPADGDCLLVEAVQ-ADQVVA MSMEG_3796|M.smegmatis_MC2_155 EMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQ-GDEVVA Mb1667c|M.bovis_AF2122/97 EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA Rv1640c|M.tuberculosis_H37Rv EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA MMAR_2447|M.marinum_M EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA MUL_1626|M.ulcerans_Agy99 EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA MAV_3128|M.avium_104 AMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVA MLBr_01393|M.leprae_Br4923 EMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVA MAB_2319c|M.abscessus_ATCC_199 ETKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVA TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK MLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLN Mvan_3330|M.vanbaalenii_PYR-1 MLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLN MSMEG_3796|M.smegmatis_MC2_155 MLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLN Mb1667c|M.bovis_AF2122/97 MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN Rv1640c|M.tuberculosis_H37Rv MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN MMAR_2447|M.marinum_M MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN MUL_1626|M.ulcerans_Agy99 MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN MAV_3128|M.avium_104 MLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLN MLBr_01393|M.leprae_Br4923 ILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLN MAB_2319c|M.abscessus_ATCC_199 MLSLVPWGTNGVSLELMRRSRQSPNGTIEFMVTELLTRAEGMGITRVSLN TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW Mvan_3330|M.vanbaalenii_PYR-1 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW MSMEG_3796|M.smegmatis_MC2_155 FAMFRSAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEW Mb1667c|M.bovis_AF2122/97 FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW Rv1640c|M.tuberculosis_H37Rv FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW MMAR_2447|M.marinum_M FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW MUL_1626|M.ulcerans_Agy99 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW MAV_3128|M.avium_104 FAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDW MLBr_01393|M.leprae_Br4923 FTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDW MAB_2319c|M.abscessus_ATCC_199 FVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEW TH_2348|M.thermoresistible__bu -------------------------------------------------- Mflv_3544|M.gilvum_PYR-GCK VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDL Mvan_3330|M.vanbaalenii_PYR-1 VPRYACYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTL MSMEG_3796|M.smegmatis_MC2_155 VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ-HTGEHIAAPDTL Mb1667c|M.bovis_AF2122/97 VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL Rv1640c|M.tuberculosis_H37Rv VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL MMAR_2447|M.marinum_M VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL MUL_1626|M.ulcerans_Agy99 VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL MAV_3128|M.avium_104 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKV-HTGHHPAVPARL MLBr_01393|M.leprae_Br4923 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRV-HTGHHPAVPARL MAB_2319c|M.abscessus_ATCC_199 VPRFACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAI TH_2348|M.thermoresistible__bu --------------------------------------------VTPPES ..* Mflv_3544|M.gilvum_PYR-GCK IATGRLHSDGTAPDRIGPVGDGADDDAA--PRLPEQVRVRMAKLSALQDR Mvan_3330|M.vanbaalenii_PYR-1 VATGLLHSDGTAPDGMGLQADLADDDQ---PRLPEQVRVRMAKLKALQAQ MSMEG_3796|M.smegmatis_MC2_155 VQSGRLHRDGSAPDVTGLQGELPDADDE--PRLPEQVRVRMAKLKALQGN Mb1667c|M.bovis_AF2122/97 AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS Rv1640c|M.tuberculosis_H37Rv AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS MMAR_2447|M.marinum_M AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS MUL_1626|M.ulcerans_Agy99 AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS MAV_3128|M.avium_104 AQSGLLHHDGSAPDVSGLRPE-RTDAEEARSRLPEQVRVRLAKLKVLQRN MLBr_01393|M.leprae_Br4923 AESGLLHHDGSTPDVSGLQTA-DVDLEVANSRIPEQVRVRLAKLKTLQLN MAB_2319c|M.abscessus_ATCC_199 VATGLLHHDGSTPELLPQTAP--------QQRVPEQVKVRLGKLAALQEK TH_2348|M.thermoresistible__bu VDP----------------------------DLPEQFRIRQAKRADLLAQ . :***.::* * * Mflv_3544|M.gilvum_PYR-GCK GVDAYPVGSPPSHTIAEA--------IAAEEGTEVTVSGRVLRARDYGGV Mvan_3330|M.vanbaalenii_PYR-1 GVDAYPVANPPSHTVAQA--------LAAEDGADVAVAGRVLRSRDYGGV MSMEG_3796|M.smegmatis_MC2_155 GVDAYPVGQPPSHTVAQA--------LGATDGETLSVAGRVMRIRDYGGV Mb1667c|M.bovis_AF2122/97 GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV Rv1640c|M.tuberculosis_H37Rv GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV MMAR_2447|M.marinum_M GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV MUL_1626|M.ulcerans_Agy99 GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV MAV_3128|M.avium_104 GVDAYPVGCPPSHTVAQA--------LDADDQQDITVAGRILRIRDFGGV MLBr_01393|M.leprae_Br4923 GIDAYPVGHPPSHTVAQA--------LDADDEGTVSISGRILRIRDYGGV MAB_2319c|M.abscessus_ATCC_199 GIDTYPVGSPPSHTVAEA--------LAAPDGSEVVISGRLLRIRDYGGV TH_2348|M.thermoresistible__bu GRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKL * :.:** * :**: : : * : ::**:: *: * : Mflv_3544|M.gilvum_PYR-GCK LFGQLRDWSA-ETQVALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTR Mvan_3330|M.vanbaalenii_PYR-1 LFAQLRDWSG-ETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSR MSMEG_3796|M.smegmatis_MC2_155 LFAQLRDWSG-EVQLLLDNAALTEGETADFTATIDLGDLVEVTGSMGFSR Mb1667c|M.bovis_AF2122/97 LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK Rv1640c|M.tuberculosis_H37Rv LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK MMAR_2447|M.marinum_M LFAHLRDWSG-EIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSK MUL_1626|M.ulcerans_Agy99 LFAHLRDWSG-EIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSK MAV_3128|M.avium_104 LFAQLRDWSG-EMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSK MLBr_01393|M.leprae_Br4923 LFAHVRDWSG-EIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSK MAB_2319c|M.abscessus_ATCC_199 LFAQLRDWSA-EVQLLIDDPRLH----EEFTAAVDLGDLVEASGVMGQSN TH_2348|M.thermoresistible__bu CFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSK *. ::: .. : * :. : ::. *:**:: * : :. Mflv_3544|M.gilvum_PYR-GCK SGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE Mvan_3330|M.vanbaalenii_PYR-1 SGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE MSMEG_3796|M.smegmatis_MC2_155 NGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARD Mb1667c|M.bovis_AF2122/97 TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA Rv1640c|M.tuberculosis_H37Rv TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA MMAR_2447|M.marinum_M TGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRA MUL_1626|M.ulcerans_Agy99 TGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRT MAV_3128|M.avium_104 KGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRE MLBr_01393|M.leprae_Br4923 NGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRN MAB_2319c|M.abscessus_ATCC_199 NGTRSVLVESWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEARE TH_2348|M.thermoresistible__bu RGELSVLADSWQMAAKALRPLPVAHKEMSE-ESRVRQRYVDLIVRDQARK * *::. *:: .*.*:*** : : : *:*** **:** :. ::* Mflv_3544|M.gilvum_PYR-GCK LIKARSAILHAIRETLVGKGFLEVETPILQQIHGGANARPFLTHINAYDL Mvan_3330|M.vanbaalenii_PYR-1 LIRARSAVLHAIRETLVAKDFLEVETPILQQIHGGANARPFLTHINAYDL MSMEG_3796|M.smegmatis_MC2_155 LIRARSGALHAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDL Mb1667c|M.bovis_AF2122/97 LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM Rv1640c|M.tuberculosis_H37Rv LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM MMAR_2447|M.marinum_M LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM MUL_1626|M.ulcerans_Agy99 LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM MAV_3128|M.avium_104 LIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDM MLBr_01393|M.leprae_Br4923 LIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDM MAB_2319c|M.abscessus_ATCC_199 QIAARSAIITSLRNTLLAQGFLEVETPILQQVHGGANARPFLTHINAYNL TH_2348|M.thermoresistible__bu VARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDT * : ::*. * :.*:*****:** : *** **** *: *: . Mflv_3544|M.gilvum_PYR-GCK DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Mvan_3330|M.vanbaalenii_PYR-1 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MSMEG_3796|M.smegmatis_MC2_155 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Mb1667c|M.bovis_AF2122/97 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ Rv1640c|M.tuberculosis_H37Rv DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MMAR_2447|M.marinum_M DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MUL_1626|M.ulcerans_Agy99 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MAV_3128|M.avium_104 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MLBr_01393|M.leprae_Br4923 DLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ MAB_2319c|M.abscessus_ATCC_199 DLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTLLEAYQ TH_2348|M.thermoresistible__bu ELYLRIAPELFLKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQ :*:*******:*** :**.*:****.*.*****.* :*.***.:**:** Mflv_3544|M.gilvum_PYR-GCK AHADYTVWIDGCRELIQNAAMAANGSHVFFRP----RED---GVLEPVDI Mvan_3330|M.vanbaalenii_PYR-1 AHADYHVWIDGCRELIQNAAQAANGAQVFMRP----RAD---GVLEPVDI MSMEG_3796|M.smegmatis_MC2_155 AHADYNVWIDGCRELIQNAAQAANGAQVFLRP----RPNDPAGTLEPVDI Mb1667c|M.bovis_AF2122/97 AHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI Rv1640c|M.tuberculosis_H37Rv AHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI MMAR_2447|M.marinum_M AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVDI MUL_1626|M.ulcerans_Agy99 AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVGI MAV_3128|M.avium_104 AHADYRVWIDGCRELIQNAAQAAHGEQTVLRP-------GADGRLQPVDI MLBr_01393|M.leprae_Br4923 AHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIE-GASGTANHLEPIDI MAB_2319c|M.abscessus_ATCC_199 AHADYVTWAQTTQRLIQNAAKAAHGAEVVMRP-------GADGRLAPVDI TH_2348|M.thermoresistible__bu AYGTYDDSAVVTRELIQEVADEAIGTRQVPLP-----------DGTVYDL *:. * :.***:.* * * * .: Mflv_3544|M.gilvum_PYR-GCK SGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCD--KAGIPYLTHWDAG Mvan_3330|M.vanbaalenii_PYR-1 SGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCD--RAGIPYLTHWDAG MSMEG_3796|M.smegmatis_MC2_155 SGQWAVKTVHDAVSEAIGEHITPETELGELRRLCD--SAGIPYLTHWDAG Mb1667c|M.bovis_AF2122/97 SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG Rv1640c|M.tuberculosis_H37Rv SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG MMAR_2447|M.marinum_M SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG MUL_1626|M.ulcerans_Agy99 SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG MAV_3128|M.avium_104 SGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSD--AARIPYRAHWDAG MLBr_01393|M.leprae_Br4923 SGVWPVKTVYEAVSEALGECVDTSTELATLRKLSD--AAHIPYWPHWDTG MAB_2319c|M.abscessus_ATCC_199 GGEWPIVPVHEAVSRALGEEVNAATEVPTLQRFCQ--SAEVQFNPRWDAG TH_2348|M.thermoresistible__bu DGEWESIQMYPSLSEALGEEITPDTPAETLWAIADRLGLDIPRDRGYGHG .* * :: ::*.*:** : * * :.: : :. * Mflv_3544|M.gilvum_PYR-GCK AVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW Mvan_3330|M.vanbaalenii_PYR-1 AVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW MSMEG_3796|M.smegmatis_MC2_155 AVVLEMYEHLVEDRTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW Mb1667c|M.bovis_AF2122/97 AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW Rv1640c|M.tuberculosis_H37Rv AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW MMAR_2447|M.marinum_M AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW MUL_1626|M.ulcerans_Agy99 AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW MAV_3128|M.avium_104 AVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAW MLBr_01393|M.leprae_Br4923 AVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAW MAB_2319c|M.abscessus_ATCC_199 HLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSIAGLAERWDLVAW TH_2348|M.thermoresistible__bu KLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVR :* :::*: * : *** ***...:****.*** *::*:*** . Mflv_3544|M.gilvum_PYR-GCK GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM Mvan_3330|M.vanbaalenii_PYR-1 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MSMEG_3796|M.smegmatis_MC2_155 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM Mb1667c|M.bovis_AF2122/97 GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM Rv1640c|M.tuberculosis_H37Rv GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MMAR_2447|M.marinum_M GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM MUL_1626|M.ulcerans_Agy99 GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM MAV_3128|M.avium_104 GVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM MLBr_01393|M.leprae_Br4923 GIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAM MAB_2319c|M.abscessus_ATCC_199 GVELGTAYTELTDPVEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAM TH_2348|M.thermoresistible__bu RIELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGM :**.*.*:*****: ** *: *: *..*: *** ****** *:**.* Mflv_3544|M.gilvum_PYR-GCK PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR Mvan_3330|M.vanbaalenii_PYR-1 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR MSMEG_3796|M.smegmatis_MC2_155 PPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR Mb1667c|M.bovis_AF2122/97 PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH Rv1640c|M.tuberculosis_H37Rv PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH MMAR_2447|M.marinum_M PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH MUL_1626|M.ulcerans_Agy99 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH MAV_3128|M.avium_104 PPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH MLBr_01393|M.leprae_Br4923 PPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH MAB_2319c|M.abscessus_ATCC_199 APTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR TH_2348|M.thermoresistible__bu PPSTGTGMGIDRLMMTLTGLSIRETVLFPIVKPR .*: * ***:**::* :** *****: **:.**: