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VAWVPAAAGWTVGVIATLSLIASVSPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRI AWWVLVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEFWAKVRRGALLKSAAVL VAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNRVSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAA IVLFQSQRASNALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDP VGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLNALQLGDEAILHPDRFRLSGPDMRAVR QAVTRARRAGTSVRIRRHRELSPEEMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQGDE VVAMLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLNFAMFRSAFEQGAQLGAG PVARLWRALLVFFSKWWQLESLYRSNMKYQPEWVPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ HTGEHIAAPDTLVQSGRLHRDGSAPDVTGLQGELPDADDEPRLPEQVRVRMAKLKALQGNGVDAYPVGQP PSHTVAQALGATDGETLSVAGRVMRIRDYGGVLFAQLRDWSGEVQLLLDNAALTEGETADFTATIDLGDL VEVTGSMGFSRNGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGAL HAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRA FRNEGVDFSHNPEFTLLEAYQAHADYNVWIDGCRELIQNAAQAANGAQVFLRPRPNDPAGTLEPVDISGQ WAVKTVHDAVSEAIGEHITPETELGELRRLCDSAGIPYLTHWDAGAVVLEMYEHLVEDRTTEPTFYKDFP TSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQA MEYAMPPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3796 | lysS | - | 100% (1089) | lysyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_6094 | lysS | e-121 | 47.72% (505) | lysyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_3003 | aspS | 2e-17 | 29.96% (237) | aspartyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1667c | lysS | 0.0 | 75.94% (1093) | lysyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_3544 | lysS | 0.0 | 81.91% (1089) | lysyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv1640c | lysS | 0.0 | 76.03% (1093) | lysyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01393 | lysS | 0.0 | 75.14% (1038) | lysyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_2319c | lysS | 0.0 | 67.77% (1089) | lysyl-tRNA synthetase |
| M. marinum M | MMAR_2447 | lysS | 0.0 | 77.32% (1089) | lysyl-tRNA synthetase 2 LysX |
| M. avium 104 | MAV_3128 | lysS | 0.0 | 78.55% (1077) | lysyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_2348 | lysS | 1e-120 | 47.34% (507) | LYSYL-TRNA SYNTHETASE 1 LYSS (LYSINE--TRNA LIGASE 1) (LYSRS 1) |
| M. ulcerans Agy99 | MUL_1626 | lysS | 0.0 | 76.86% (1089) | lysyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_3330 | lysS | 0.0 | 83.92% (1088) | lysyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3544|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3796|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01393|M.leprae_Br4923 --------------------------------------------------
MAV_3128|M.avium_104 --------------------------------------------------
Mb1667c|M.bovis_AF2122/97 MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG
Rv1640c|M.tuberculosis_H37Rv MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPG
MMAR_2447|M.marinum_M --------------------------------------------------
MUL_1626|M.ulcerans_Agy99 --------------------------------------------------
MAB_2319c|M.abscessus_ATCC_199 ---------------------------------------MTSIKPAVEPP
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK ------------MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASV
Mvan_3330|M.vanbaalenii_PYR-1 ------------MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASV
MSMEG_3796|M.smegmatis_MC2_155 --------------------------MAWVPAAAGWTVGVIATLSLIASV
MLBr_01393|M.leprae_Br4923 --------------------------------------------------
MAV_3128|M.avium_104 ---------------------------------------MIATVSLLGSV
Mb1667c|M.bovis_AF2122/97 ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV
Rv1640c|M.tuberculosis_H37Rv ISRLLGISSRSVTLTKPRSATRGNSRYHWVPAAAGWTVGVIATLSLLASV
MMAR_2447|M.marinum_M ------------------MQGRHISRYDWVPAAAGWAVGVIATLSLLASI
MUL_1626|M.ulcerans_Agy99 ------------------MQSRHISRYDWVPAAAGWAVGVIATLSLLASI
MAB_2319c|M.abscessus_ATCC_199 APDHPAVTALPGIGARPAARPPVTSRWRWVPAFFGWFVGIQAILNFLSSI
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK SPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI
Mvan_3330|M.vanbaalenii_PYR-1 SPLVRSLIRVPREWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWI
MSMEG_3796|M.smegmatis_MC2_155 SPLVRSLIRVPREFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWV
MLBr_01393|M.leprae_Br4923 -------------------------------MLALLAAALTTRKRIAWLL
MAV_3128|M.avium_104 SPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLL
Mb1667c|M.bovis_AF2122/97 SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV
Rv1640c|M.tuberculosis_H37Rv SPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLV
MMAR_2447|M.marinum_M SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL
MUL_1626|M.ulcerans_Agy99 SPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLL
MAB_2319c|M.abscessus_ATCC_199 SPFIRMVTKLPREFVDEYLFGWPDGSLSWAFVLSLLAAALAVRKSIAWWV
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK LTGYMVAAAVWNVTGLLDG-DRWFEDVGEIIGLGFHLAAIASLLLARREF
Mvan_3330|M.vanbaalenii_PYR-1 LVGYMIAAAGWNIAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEF
MSMEG_3796|M.smegmatis_MC2_155 LVLYLVGAIGWNVGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEF
MLBr_01393|M.leprae_Br4923 LLGNMVLAAVLNAVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREF
MAV_3128|M.avium_104 LLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREF
Mb1667c|M.bovis_AF2122/97 LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF
Rv1640c|M.tuberculosis_H37Rv LLANMVLAAVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREF
MMAR_2447|M.marinum_M LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQF
MUL_1626|M.ulcerans_Agy99 LLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFEVHVVAIVVLVLGYRQF
MAB_2319c|M.abscessus_ATCC_199 LLIDLLGRSALNVGGFIEH-----RDTTELIGLVVHGAFILLLLLARKEF
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK WARVRPGALVKAAVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNR
Mvan_3330|M.vanbaalenii_PYR-1 WARVRRGALLKAAATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNR
MSMEG_3796|M.smegmatis_MC2_155 WAKVRRGALLKSAAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNR
MLBr_01393|M.leprae_Br4923 WAKVRRGALFKAAAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANR
MAV_3128|M.avium_104 WAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNR
Mb1667c|M.bovis_AF2122/97 WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR
Rv1640c|M.tuberculosis_H37Rv WAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAANR
MMAR_2447|M.marinum_M WAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANR
MUL_1626|M.ulcerans_Agy99 WTKVRRGALFKAAAVLVAGGAIGILVSWGLVDLFPGSLAPHDRLPYVANR
MAB_2319c|M.abscessus_ATCC_199 YAKVRRGATVKAALVLIAGMAAGTVLAWGLLELFPRTLVPGDRFWWALNR
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK VGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALT
Mvan_3330|M.vanbaalenii_PYR-1 VSAFAGADAASFSGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALT
MSMEG_3796|M.smegmatis_MC2_155 VSGFATVPTEVFEGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALT
MLBr_01393|M.leprae_Br4923 VVGFALADPDLFSGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALT
MAV_3128|M.avium_104 VVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALT
Mb1667c|M.bovis_AF2122/97 VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT
Rv1640c|M.tuberculosis_H37Rv VVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALT
MMAR_2447|M.marinum_M VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT
MUL_1626|M.ulcerans_Agy99 VIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALT
MAB_2319c|M.abscessus_ATCC_199 VAGFSIASHRDFDGLPPHFLNWLFGLFGALALIAAAIVLFRSQRAVNALT
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVC
Mvan_3330|M.vanbaalenii_PYR-1 GEDESAIRGLLELYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVC
MSMEG_3796|M.smegmatis_MC2_155 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVC
MLBr_01393|M.leprae_Br4923 GEDESAIRGLLELYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVC
MAV_3128|M.avium_104 GEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVC
Mb1667c|M.bovis_AF2122/97 GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC
Rv1640c|M.tuberculosis_H37Rv GEDESAIRGLLDLYGKDDSLGYFATRRDKSVVFASSGRACITYRVEVGVC
MMAR_2447|M.marinum_M GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC
MUL_1626|M.ulcerans_Agy99 GEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVC
MAB_2319c|M.abscessus_ATCC_199 GDDESLIRGLLERYGQDDSLGYFATRRDKAVIFAPNGRAAVTYRVEVGVC
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK LASGDPVGDPKAWPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLH
Mvan_3330|M.vanbaalenii_PYR-1 LASGDPVGDPRSWPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLN
MSMEG_3796|M.smegmatis_MC2_155 LASGDPVGDPKSWPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLN
MLBr_01393|M.leprae_Br4923 LASGDPVGDPGAWPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFN
MAV_3128|M.avium_104 LASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLN
Mb1667c|M.bovis_AF2122/97 LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT
Rv1640c|M.tuberculosis_H37Rv LASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT
MMAR_2447|M.marinum_M LASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN
MUL_1626|M.ulcerans_Agy99 LASGDPVGDPRSWQQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLN
MAB_2319c|M.abscessus_ATCC_199 LVSADPIGDKSAWGQAISAWLQVCDAYGWAPAVMGASAEGALAYREHGLN
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK ALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPD
Mvan_3330|M.vanbaalenii_PYR-1 ALQLGDEAILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPAD
MSMEG_3796|M.smegmatis_MC2_155 ALQLGDEAILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPE
MLBr_01393|M.leprae_Br4923 AIELGDEAILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISAN
MAV_3128|M.avium_104 ALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPE
Mb1667c|M.bovis_AF2122/97 ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED
Rv1640c|M.tuberculosis_H37Rv ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAED
MMAR_2447|M.marinum_M ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDA
MUL_1626|M.ulcerans_Agy99 ALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISGA
MAB_2319c|M.abscessus_ATCC_199 ALELGDEAILYPRSFSISGPHMATVRQAVNRARRSGLSVRIRRHRELSAE
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK EMAEVIAHADAWRDTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVA
Mvan_3330|M.vanbaalenii_PYR-1 EMAAVIERADAWRDTDDERGFSMALGRLGDPADGDCLLVEAVQ-ADQVVA
MSMEG_3796|M.smegmatis_MC2_155 EMAAVIRRADAWRDTETERGFSMALGRLGDPADDDCLLVEAVQ-GDEVVA
MLBr_01393|M.leprae_Br4923 EMADTIARADAWRDTEFERGFSMALGRLGDPADSDCLLVEAVDRDDHVVA
MAV_3128|M.avium_104 AMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVA
Mb1667c|M.bovis_AF2122/97 EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA
Rv1640c|M.tuberculosis_H37Rv EMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLA
MMAR_2447|M.marinum_M EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA
MUL_1626|M.ulcerans_Agy99 EMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVA
MAB_2319c|M.abscessus_ATCC_199 ETKQIIVNADLWRDGNTERGFSMALGRLGDSTDGDCLLVEAIDSTGDPVA
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK MLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLN
Mvan_3330|M.vanbaalenii_PYR-1 MLSLVPWGGNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLN
MSMEG_3796|M.smegmatis_MC2_155 MLSLVPWGSNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLN
MLBr_01393|M.leprae_Br4923 ILSLVPWGTTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLN
MAV_3128|M.avium_104 MLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLN
Mb1667c|M.bovis_AF2122/97 MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN
Rv1640c|M.tuberculosis_H37Rv MLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLN
MMAR_2447|M.marinum_M MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN
MUL_1626|M.ulcerans_Agy99 MLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLN
MAB_2319c|M.abscessus_ATCC_199 MLSLVPWGTNGVSLELMRRSRQSPNGTIEFMVTELLTRAEGMGITRVSLN
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW
Mvan_3330|M.vanbaalenii_PYR-1 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEW
MSMEG_3796|M.smegmatis_MC2_155 FAMFRSAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEW
MLBr_01393|M.leprae_Br4923 FTMFRAAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDW
MAV_3128|M.avium_104 FAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDW
Mb1667c|M.bovis_AF2122/97 FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW
Rv1640c|M.tuberculosis_H37Rv FAVFRAAFEQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEW
MMAR_2447|M.marinum_M FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW
MUL_1626|M.ulcerans_Agy99 FAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQW
MAB_2319c|M.abscessus_ATCC_199 FVMFRSVYADGSRIGAGPVLRLWRSVLMFASRFWQFEQLYRSNVKYQPEW
TH_2348|M.thermoresistible__bu --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDL
Mvan_3330|M.vanbaalenii_PYR-1 VPRYACYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTL
MSMEG_3796|M.smegmatis_MC2_155 VPRYACYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ-HTGEHIAAPDTL
MLBr_01393|M.leprae_Br4923 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRGRV-HTGHHPAVPARL
MAV_3128|M.avium_104 VPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKV-HTGHHPAVPARL
Mb1667c|M.bovis_AF2122/97 VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL
Rv1640c|M.tuberculosis_H37Rv VPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRV-HTGHHPAVPERL
MMAR_2447|M.marinum_M VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL
MUL_1626|M.ulcerans_Agy99 VPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKV-HTGHHPAVPERL
MAB_2319c|M.abscessus_ATCC_199 VPRFACYEDARLIPRIGIASVIAEGFLVLPFGNRDKPRHTGQYSAVPQAI
TH_2348|M.thermoresistible__bu --------------------------------------------VTPPES
..*
Mflv_3544|M.gilvum_PYR-GCK IATGRLHSDGTAPDRIGPVGDGADDDAA--PRLPEQVRVRMAKLSALQDR
Mvan_3330|M.vanbaalenii_PYR-1 VATGLLHSDGTAPDGMGLQADLADDDQ---PRLPEQVRVRMAKLKALQAQ
MSMEG_3796|M.smegmatis_MC2_155 VQSGRLHRDGSAPDVTGLQGELPDADDE--PRLPEQVRVRMAKLKALQGN
MLBr_01393|M.leprae_Br4923 AESGLLHHDGSTPDVSGLQTA-DVDLEVANSRIPEQVRVRLAKLKTLQLN
MAV_3128|M.avium_104 AQSGLLHHDGSAPDVSGLRPE-RTDAEEARSRLPEQVRVRLAKLKVLQRN
Mb1667c|M.bovis_AF2122/97 AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS
Rv1640c|M.tuberculosis_H37Rv AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSS
MMAR_2447|M.marinum_M AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS
MUL_1626|M.ulcerans_Agy99 AATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSS
MAB_2319c|M.abscessus_ATCC_199 VATGLLHHDGSTPELLPQTAP--------QQRVPEQVKVRLGKLAALQEK
TH_2348|M.thermoresistible__bu VDP----------------------------DLPEQFRIRQAKRADLLAQ
. :***.::* * *
Mflv_3544|M.gilvum_PYR-GCK GVDAYPVGSPPSHTIAEA--------IAAEEGTEVTVSGRVLRARDYGGV
Mvan_3330|M.vanbaalenii_PYR-1 GVDAYPVANPPSHTVAQA--------LAAEDGADVAVAGRVLRSRDYGGV
MSMEG_3796|M.smegmatis_MC2_155 GVDAYPVGQPPSHTVAQA--------LGATDGETLSVAGRVMRIRDYGGV
MLBr_01393|M.leprae_Br4923 GIDAYPVGHPPSHTVAQA--------LDADDEGTVSISGRILRIRDYGGV
MAV_3128|M.avium_104 GVDAYPVGCPPSHTVAQA--------LDADDQQDITVAGRILRIRDFGGV
Mb1667c|M.bovis_AF2122/97 GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV
Rv1640c|M.tuberculosis_H37Rv GIDAFPVGRPPSHTVAQA--------LAADHQASVSVSGRIMRIRNYGGV
MMAR_2447|M.marinum_M GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV
MUL_1626|M.ulcerans_Agy99 GIDAYPVGEPPTHTVAQA--------MDADDQASVSVSGRILRVRNYGGV
MAB_2319c|M.abscessus_ATCC_199 GIDTYPVGSPPSHTVAEA--------LAAPDGSEVVISGRLLRIRDYGGV
TH_2348|M.thermoresistible__bu GRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKL
* :.:** * :**: : : * : ::**:: *: * :
Mflv_3544|M.gilvum_PYR-GCK LFGQLRDWSA-ETQVALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTR
Mvan_3330|M.vanbaalenii_PYR-1 LFAQLRDWSG-ETQLVLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSR
MSMEG_3796|M.smegmatis_MC2_155 LFAQLRDWSG-EVQLLLDNAALTEGETADFTATIDLGDLVEVTGSMGFSR
MLBr_01393|M.leprae_Br4923 LFAHVRDWSG-EIQVLLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSK
MAV_3128|M.avium_104 LFAQLRDWSG-EMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSK
Mb1667c|M.bovis_AF2122/97 LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK
Rv1640c|M.tuberculosis_H37Rv LFAQLRDWSG-EMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASK
MMAR_2447|M.marinum_M LFAHLRDWSG-EIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSK
MUL_1626|M.ulcerans_Agy99 LFAHLRDWSG-EIQVLLDNSRLGQGRAADFNAAIDLGDLVEMTGQMGSSK
MAB_2319c|M.abscessus_ATCC_199 LFAQLRDWSA-EVQLLIDDPRLH----EEFTAAVDLGDLVEASGVMGQSN
TH_2348|M.thermoresistible__bu CFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSK
*. ::: .. : * :. : ::. *:**:: * : :.
Mflv_3544|M.gilvum_PYR-GCK SGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE
Mvan_3330|M.vanbaalenii_PYR-1 SGKWSLLVSGWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARE
MSMEG_3796|M.smegmatis_MC2_155 NGTRSLLVERWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARD
MLBr_01393|M.leprae_Br4923 NGTRSLIVRNWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRN
MAV_3128|M.avium_104 KGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRE
Mb1667c|M.bovis_AF2122/97 TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA
Rv1640c|M.tuberculosis_H37Rv TGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA
MMAR_2447|M.marinum_M TGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRA
MUL_1626|M.ulcerans_Agy99 TGTRSLIVRRWRLIGKCLRPLPNKWNGLTDPEARVRTRYVDLAVNAESRT
MAB_2319c|M.abscessus_ATCC_199 NGTRSVLVESWRIIGKCLHPLPDKRKGLTDPEARVRARYLDLAINPEARE
TH_2348|M.thermoresistible__bu RGELSVLADSWQMAAKALRPLPVAHKEMSE-ESRVRQRYVDLIVRDQARK
* *::. *:: .*.*:*** : : : *:*** **:** :. ::*
Mflv_3544|M.gilvum_PYR-GCK LIKARSAILHAIRETLVGKGFLEVETPILQQIHGGANARPFLTHINAYDL
Mvan_3330|M.vanbaalenii_PYR-1 LIRARSAVLHAIRETLVAKDFLEVETPILQQIHGGANARPFLTHINAYDL
MSMEG_3796|M.smegmatis_MC2_155 LIRARSGALHAIRETLYSKGFLEVETPILQQIHGGANARPFLTHINAYDL
MLBr_01393|M.leprae_Br4923 LIMARSCVLRSVREMLFAKGFVEVETPILQQIHGGATARPFATRINTYDM
MAV_3128|M.avium_104 LIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDM
Mb1667c|M.bovis_AF2122/97 LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM
Rv1640c|M.tuberculosis_H37Rv LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSM
MMAR_2447|M.marinum_M LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM
MUL_1626|M.ulcerans_Agy99 LITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSM
MAB_2319c|M.abscessus_ATCC_199 QIAARSAIITSLRNTLLAQGFLEVETPILQQVHGGANARPFLTHINAYNL
TH_2348|M.thermoresistible__bu VARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDT
* : ::*. * :.*:*****:** : *** **** *: *: .
Mflv_3544|M.gilvum_PYR-GCK DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Mvan_3330|M.vanbaalenii_PYR-1 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MSMEG_3796|M.smegmatis_MC2_155 DLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MLBr_01393|M.leprae_Br4923 DLFLRIAPELYLKRLCIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MAV_3128|M.avium_104 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Mb1667c|M.bovis_AF2122/97 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
Rv1640c|M.tuberculosis_H37Rv DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MMAR_2447|M.marinum_M DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MUL_1626|M.ulcerans_Agy99 DLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQ
MAB_2319c|M.abscessus_ATCC_199 DLYLRIAPELYLKRLCVGGVEKVFELGRAFRNEGVDFSHNPEFTLLEAYQ
TH_2348|M.thermoresistible__bu ELYLRIAPELFLKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQ
:*:*******:*** :**.*:****.*.*****.* :*.***.:**:**
Mflv_3544|M.gilvum_PYR-GCK AHADYTVWIDGCRELIQNAAMAANGSHVFFRP----RED---GVLEPVDI
Mvan_3330|M.vanbaalenii_PYR-1 AHADYHVWIDGCRELIQNAAQAANGAQVFMRP----RAD---GVLEPVDI
MSMEG_3796|M.smegmatis_MC2_155 AHADYNVWIDGCRELIQNAAQAANGAQVFLRP----RPNDPAGTLEPVDI
MLBr_01393|M.leprae_Br4923 AHADYLMWIDGCRELIQNAAEAANGTQTLMRPRIE-GASGTANHLEPIDI
MAV_3128|M.avium_104 AHADYRVWIDGCRELIQNAAQAAHGEQTVLRP-------GADGRLQPVDI
Mb1667c|M.bovis_AF2122/97 AHAGYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI
Rv1640c|M.tuberculosis_H37Rv AHADYLEWIDGCRELIQNAAQAANGAPIAMRPRTDKGSDGTRHHLEPVDI
MMAR_2447|M.marinum_M AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVDI
MUL_1626|M.ulcerans_Agy99 AHADYRVWIDSCRELIQNAAQAANGAPVAMRP-----AGGGR--LEPVGI
MAB_2319c|M.abscessus_ATCC_199 AHADYVTWAQTTQRLIQNAAKAAHGAEVVMRP-------GADGRLAPVDI
TH_2348|M.thermoresistible__bu AYGTYDDSAVVTRELIQEVADEAIGTRQVPLP-----------DGTVYDL
*:. * :.***:.* * * * .:
Mflv_3544|M.gilvum_PYR-GCK SGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCD--KAGIPYLTHWDAG
Mvan_3330|M.vanbaalenii_PYR-1 SGPWTVKTVHGAVSEALGEQIGPDTDLATLRLLCD--RAGIPYLTHWDAG
MSMEG_3796|M.smegmatis_MC2_155 SGQWAVKTVHDAVSEAIGEHITPETELGELRRLCD--SAGIPYLTHWDAG
MLBr_01393|M.leprae_Br4923 SGVWPVKTVYEAVSEALGECVDTSTELATLRKLSD--AAHIPYWPHWDTG
MAV_3128|M.avium_104 SGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSD--AARIPYRAHWDAG
Mb1667c|M.bovis_AF2122/97 SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG
Rv1640c|M.tuberculosis_H37Rv SGIWPVRTVHDAISEALGERIDADTGLTTLRKLCD--AAGVPYRTQWDAG
MMAR_2447|M.marinum_M SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG
MUL_1626|M.ulcerans_Agy99 SGVWAVKTVHDAVSEALGEQIDADTDLATLRRLAD--AARIPYRAQWDAG
MAB_2319c|M.abscessus_ATCC_199 GGEWPIVPVHEAVSRALGEEVNAATEVPTLQRFCQ--SAEVQFNPRWDAG
TH_2348|M.thermoresistible__bu DGEWESIQMYPSLSEALGEEITPDTPAETLWAIADRLGLDIPRDRGYGHG
.* * :: ::*.*:** : * * :.: : :. *
Mflv_3544|M.gilvum_PYR-GCK AVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
Mvan_3330|M.vanbaalenii_PYR-1 AVVLELYEHLVEDQTREPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
MSMEG_3796|M.smegmatis_MC2_155 AVVLEMYEHLVEDRTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAW
MLBr_01393|M.leprae_Br4923 AVVLKLYEHLVENRTDQPTFYIDFPTSVSPLTRPHRSKPGVAERWDLVAW
MAV_3128|M.avium_104 AVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAW
Mb1667c|M.bovis_AF2122/97 AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW
Rv1640c|M.tuberculosis_H37Rv AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAW
MMAR_2447|M.marinum_M AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW
MUL_1626|M.ulcerans_Agy99 AVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAW
MAB_2319c|M.abscessus_ATCC_199 HLVLELYERLVEKHTTSPTFYSDFPVSVSPLTRPHRSIAGLAERWDLVAW
TH_2348|M.thermoresistible__bu KLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVR
:* :::*: * : *** ***...:****.*** *::*:*** .
Mflv_3544|M.gilvum_PYR-GCK GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
Mvan_3330|M.vanbaalenii_PYR-1 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MSMEG_3796|M.smegmatis_MC2_155 GVELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MLBr_01393|M.leprae_Br4923 GIELGTAYSELTDPVEQRRRLHEQSLLAVGGNPEAMELDEDFLQAMEYAM
MAV_3128|M.avium_104 GVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
Mb1667c|M.bovis_AF2122/97 GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
Rv1640c|M.tuberculosis_H37Rv GIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAM
MMAR_2447|M.marinum_M GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM
MUL_1626|M.ulcerans_Agy99 GVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAM
MAB_2319c|M.abscessus_ATCC_199 GVELGTAYTELTDPVEQRRRLYEQSLLAAGGDAEAMELDEDFLRAMEYAM
TH_2348|M.thermoresistible__bu RIELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGM
:**.*.*:*****: ** *: *: *..*: *** ****** *:**.*
Mflv_3544|M.gilvum_PYR-GCK PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR
Mvan_3330|M.vanbaalenii_PYR-1 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR
MSMEG_3796|M.smegmatis_MC2_155 PPTGGLGMGVDRVVMMITGRSIRETLPFPLAKPR
MLBr_01393|M.leprae_Br4923 PPTGGLGMGIDRLVMLITGRSIRETLPFPLAKPH
MAV_3128|M.avium_104 PPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH
Mb1667c|M.bovis_AF2122/97 PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH
Rv1640c|M.tuberculosis_H37Rv PPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH
MMAR_2447|M.marinum_M PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
MUL_1626|M.ulcerans_Agy99 PPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
MAB_2319c|M.abscessus_ATCC_199 APTGGMGMGVDRVVMLITGRSIRETLPFPLAKPR
TH_2348|M.thermoresistible__bu PPSTGTGMGIDRLMMTLTGLSIRETVLFPIVKPR
.*: * ***:**::* :** *****: **:.**: