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MTDEERFSLLLGVMGAGDLWPLRDERIPADVPMSAGYVPGIARLGVPALLMTDAGLGVTNPGYRPGDTAT ALPAGLALAASFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDPFLTAAMVAES IIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRESDLLAFEIAIERAQPGAVVAAYNKVNGVYAT ANGELINEVLKGAWGYRGWVMSDWGGTPGWECALGGLDQECGAQIDAILWQSEAFGDPLRAAYHEGRLPK ARLSEMVRRILRSMFAVGVDRWEPAPAPDMDAHDEVAAEIARQGIVLLQNRGVLPLRPAPGTRIAVIGGY AQLGVLAGYGSSAVVPPGGYAEVIPIGGAGLTPGVRNLYLLGSSPLDELRTQFGNAELEFDPGINPAEAV AVARRADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVLEGGNPVAMPWQDSVNAIVQA WYPGQAGARVIAEVLAGRVNPCGRLPITFPVGLGQTPRPELPGYGAPVGAPMRIHYREGADIGYRWFATT GEVPNFAFGHGLTYTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQVYLTAVTGEPRLRLLGFERVE LEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVGASAAALSAVAEAELAGRTFGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1080 | bglS | - | 100% (691) | beta-glucosidase BglS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0192 | bglS | 0.0 | 78.73% (691) | beta-glucosidase BGLS |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0186 | bglS | 0.0 | 78.87% (691) | beta-glucosidase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4458c | - | 2e-05 | 23.79% (269) | putative secreted hydrolase |
| M. marinum M | MMAR_0430 | bglS | 0.0 | 98.84% (691) | beta-glucosidase BglS |
| M. avium 104 | MAV_4994 | - | 0.0 | 77.13% (691) | glycosyl hydrolase family protein 3 |
| M. smegmatis MC2 155 | MSMEG_2556 | - | 2e-83 | 34.26% (680) | beta-glucosidase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1080|M.ulcerans_Agy99 --------------------MTDEERFSLLLGVMGAGDLWPLRDERIPAD
MMAR_0430|M.marinum_M MSSSGHNAPADVRARQVESEMTDEERFSLLLGVMGAGDLWPLRDERIPAD
Mb0192|M.bovis_AF2122/97 --------------------MTDDERFSLLVGLTGASDLWPVRDERIPQG
Rv0186|M.tuberculosis_H37Rv --------------------MTDDERFSLLVGLTGASDLWPVRDERIPQG
MAV_4994|M.avium_104 ------MKDPDERARTVEAQMTDDERFSLLVAVMGAGDMWPVRDERIPAD
MSMEG_2556|M.smegmatis_MC2_155 --------------------MTDPLAHAPTLTLTQQAALGSGASFWTTEA
MAB_4458c|M.abscessus_ATCC_199 ---------------------------------MRAGTVLTG---LVVAA
. : .
MUL_1080|M.ulcerans_Agy99 VPMSAGYVPGIARLGVPALLMTDAGLGVTNPGYRPGDTATALPAGLALAA
MMAR_0430|M.marinum_M VPMSAGYVPGIARLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
Mb0192|M.bovis_AF2122/97 VPMCAGYVPGIPRLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
Rv0186|M.tuberculosis_H37Rv VPMCAGYVPGIPRLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
MAV_4994|M.avium_104 VPMSAGYVPGVPRLGVPPLLMSDAGLGVTNPGYRPGDTATALPAGLALAA
MSMEG_2556|M.smegmatis_MC2_155 VGHIPSIVLTDGPHGVRRQSGASDHLGVGGS-----EPATCFPPAVALSQ
MAB_4458c|M.abscessus_ATCC_199 LTACGGNASEPSKENTSSTKAQAP--------------ATAAPAADLACL
: . . .. **. *.. .
MUL_1080|M.ulcerans_Agy99 SFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
MMAR_0430|M.marinum_M SFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
Mb0192|M.bovis_AF2122/97 SFNPVLARSSGKAIGREARSRGFNVQLAGAINLARDPRNGRNFEYLSEDP
Rv0186|M.tuberculosis_H37Rv SFNPVLARSSGKAIGREARSRGFNVQLAGAINLARDPRNGRNFEYLSEDP
MAV_4994|M.avium_104 TFDPALARAAGELIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
MSMEG_2556|M.smegmatis_MC2_155 TWDPDLVERVGAALGAEARALGVHVLLGPGVNIKRDPRCGRNFEYFSEDP
MAB_4458c|M.abscessus_ATCC_199 STRDRLAQLLMVGIKDADDAR----------ALVRDHHVGG---IFVGSW
: *.. : : : ** : * : .
MUL_1080|M.ulcerans_Agy99 FLTAAMVAESIIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRES
MMAR_0430|M.marinum_M FLTAAMVAESIIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRES
Mb0192|M.bovis_AF2122/97 LLSATMAAESIIGIQQQGVIATTKHFSLNCNETNRHWLDAVIDPDAHRES
Rv0186|M.tuberculosis_H37Rv LLSATMAAESIIGIQQQGVIATTKHFSLNCNETNRHWLDAVIDPDAHRES
MAV_4994|M.avium_104 LLTAAMVAESVAGIQQQGVISTVKHYSLNCNETNRHFLDAVIDPDAHRES
MSMEG_2556|M.smegmatis_MC2_155 LLSGVLGAAWVRGVQGRGVGASLKHFAVNNSEHDRMRASSDVDARTLREI
MAB_4458c|M.abscessus_ATCC_199 TKKEMLTDGSLHDVITAGPIP----------------AAVSIDEEGGRVS
. : : .: * . :* *
MUL_1080|M.ulcerans_Agy99 DLLAFEIAIERAQPGAVVAAYNKVNGVYATANGELINEVLKGAWGYRGWV
MMAR_0430|M.marinum_M DLLAFEIAIERAQPGAVMAAYNKVNGVYAAANGELINEVLKGAWGYRGWV
Mb0192|M.bovis_AF2122/97 DLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLNDVLKGAWGYRGWV
Rv0186|M.tuberculosis_H37Rv DLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLNDVLKGAWGYRGWV
MAV_4994|M.avium_104 DLLAFELAIERAQPGAVMTAYNKVNGVYAAANSVLLNDVLKDAWAYRGWV
MSMEG_2556|M.smegmatis_MC2_155 YLRAFEHVVREAAPWTVMCSNNRINGVYASENTWLLTDVLRGEWGFDGVV
MAB_4458c|M.abscessus_ATCC_199 RLKDLIGPAPSARELAATQTPEQVQALSQERAQKMKDLGITIDFAPDADV
* : : :. : ::::. : : :. . *
MUL_1080|M.ulcerans_Agy99 MSDWGGTPGWECALGGLDQECGAQIDAILWQSEAFGDPLRAAYHEGRLPK
MMAR_0430|M.marinum_M MSDWGGTPGWECALGGLDQECGAQIDAILWQSEAFGDPLRAAYHEGRLPK
Mb0192|M.bovis_AF2122/97 MSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADGNLPK
Rv0186|M.tuberculosis_H37Rv MSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADGNLPK
MAV_4994|M.avium_104 MSDWGATPGWECALGGLDQECGAQIDALLWQAESFGAPLRDAYADGRLPK
MSMEG_2556|M.smegmatis_MC2_155 VSDWGAVRDRVAAVA-------AGLDLEMPSSGGFGDAEVVAAVTAGALD
MAB_4458c|M.abscessus_ATCC_199 TD--------------------GDPDGAIGDRSFSGDPQKVAEYAEASVR
. . * : . *
MUL_1080|M.ulcerans_Agy99 ARLSEMVRRILRSMFAVGVDRWEPAPAPDM----DAHDEVAAEIARQGIV
MMAR_0430|M.marinum_M ARLSEMVRRILRSMFAVGVDRWEPAPAPDM----DAHDEVAAEIARQGIV
Mb0192|M.bovis_AF2122/97 GRLSDMVRRILRSMFAVGIDRWKPAPAPDM----NAHNEIAAQMARQGIV
Rv0186|M.tuberculosis_H37Rv GRLSDMVRRILRSMFAVGIDRWKPAPAPDM----NAHNEIAAQMARQGIV
MAV_4994|M.avium_104 DRLSDMVRRILRSIFAVGVDRSDRAPAPDL----NAHNDIALRIARQGIV
MSMEG_2556|M.smegmatis_MC2_155 ARAVTTAAERVAGLAVRAYESHSAAGHFDIGELTEAHHRLACEAAAQAVV
MAB_4458c|M.abscessus_ATCC_199 GYQAGGVRAVVKHFPGHGHAS---------------GDSHTNGVVTPPLE
. : : . . : . :
MUL_1080|M.ulcerans_Agy99 LLQN--RGVLPLRPAPGTRIAVIGGYAQLGVLAGYGSSAVVPPGGYAEVI
MMAR_0430|M.marinum_M LLQN--RGVLPLTPAPGTRIAVIGGYAQLGVVAGYGSSAVVPPGGYAEVI
Mb0192|M.bovis_AF2122/97 LLQN--RGLLPLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVI
Rv0186|M.tuberculosis_H37Rv LLQN--RGLLPLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVI
MAV_4994|M.avium_104 LLTN--RGLLPLRPDSPARIAVIGGYAQLGVPAGFGSSTVVPAGGYAAVV
MSMEG_2556|M.smegmatis_MC2_155 LLKNDLRDGEPILPLAPSRLAVIGPFAEEPRHQGGGSSHVNPTRLDIPLD
MAB_4458c|M.abscessus_ATCC_199 QLKD--NDLVPYRSLVTSGAAVMIGHMQVPGLTGDDPASLS---------
* : .. * . **: . . * ..: :
MUL_1080|M.ulcerans_Agy99 PIGGAGLTPGVRNLYLLGSSPLDELRTQFGNAELEFDPGINPAEAVAVAR
MMAR_0430|M.marinum_M PIGGAGLTAGVRNLYLLGSSPLDELRTQFGNAELEFDPGINPAEAVAVAR
Mb0192|M.bovis_AF2122/97 PIGGSGLAAGLRNLYLLPSSPLSELRKRLPNAQFEFDPGINPAEAVLAAR
Rv0186|M.tuberculosis_H37Rv PIGGSGLAAGLRNLYLLPSSPLSELRKRLPNAQFEFDPGINPAEAVLAAR
MAV_4994|M.avium_104 PIGGTALEAGLRNLYLLPSSPLQELRKLLPENTIDFDPGISPAEAVAAAQ
MSMEG_2556|M.smegmatis_MC2_155 EIRARNGDQAATHFPGLPTDSGQDSEQVR----------AEAVRGAAEAE
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1080|M.ulcerans_Agy99 RADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVLEGGN
MMAR_0430|M.marinum_M RADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVLETGN
Mb0192|M.bovis_AF2122/97 RADIAIVFAIRAEGEGFDSADLSLPWGQDALIAAVASANANTVVVLETGN
Rv0186|M.tuberculosis_H37Rv RADIAIVFAIRAEGEGFDSADLSLPWGQDALIAAVASANANTVVVLETGN
MAV_4994|M.avium_104 RADIAIVFAVRAEGEGFDLADLSLPSGQDELIGAVAAANPNTVVVLQTGN
MSMEG_2556|M.smegmatis_MC2_155 AAVLFLGLTADEESEGYDREHIDLPQAQLALLRAVVEVQPRTVVVLSHGG
MAB_4458c|M.abscessus_ATCC_199 -------------GAAVDLLRKGTGYGAPAYDGVIFTDDLSSMAAITDRF
. . * . .: : ::..:
MUL_1080|M.ulcerans_Agy99 PVAMPWQDSVN-AIVQAWYPGQAGARVIAEVLAGRVNPCGRLPITFPVGL
MMAR_0430|M.marinum_M PVAMPWQDSVN-AIVQAWYPGQAGARVIAEVLAGRVNPCGRLPITFPVGL
Mb0192|M.bovis_AF2122/97 PVTMPWRDSVN-AIMQAWYPGQAGGQAVAEIVTGQVNPSGRLPITFPVDL
Rv0186|M.tuberculosis_H37Rv PVTMPWRDSVN-AIMQAWYPGQAGGQAVAEIVTGQVNPSGRLPITFPVDL
MAV_4994|M.avium_104 PVTMPWLGAVN-AVVQAWYPGQAGATAIAEVLTGRVNPGGRLPITFPVDL
MSMEG_2556|M.smegmatis_MC2_155 VVRLDEVAKHAPAILDGALLGQAGGGAVADVLFGAVNPSGRLAETVPVRL
MAB_4458c|M.abscessus_ATCC_199 PIEEAVLKSIKAGVDWALWVSTEKVGSVLDRLESAYNAG-----------
: .: . . : : : . *.
MUL_1080|M.ulcerans_Agy99 GQTPRPELPGYGAPVGAPMRIHYREGADIGYRWFATTGEVPNFAFGHGLT
MMAR_0430|M.marinum_M GQTPRPELPGYGAPVGAPMRIHYREGADIGYRWFATTGEVPNFAFGHGLT
Mb0192|M.bovis_AF2122/97 GQTPRSQPRELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMFAFGHGLS
Rv0186|M.tuberculosis_H37Rv GQTPRSQPPELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMFAFGHGLS
MAV_4994|M.avium_104 HQTPRPQLPGAGLPWGTPSTIDYVEGADVGYRWFAAKGHVPMFAFGHGLS
MSMEG_2556|M.smegmatis_MC2_155 QDCP-----AFLNFPSENGHTVYGERVFVGYRWYDARALEVTFPFGHGLS
MAB_4458c|M.abscessus_ATCC_199 --------------ELNADAINASVRRVLAYKGVPACG------------
:.*: :
MUL_1080|M.ulcerans_Agy99 YTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQVYLTAVTG---EPR
MMAR_0430|M.marinum_M YTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQVYLTAVTG---EPR
Mb0192|M.bovis_AF2122/97 YTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPG---ESR
Rv0186|M.tuberculosis_H37Rv YTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPG---ESR
MAV_4994|M.avium_104 YTRFEHRDLVVRGGDTITAGFTVVNTGDRAGADVPQLYLTAMPG---KPC
MSMEG_2556|M.smegmatis_MC2_155 YTAFAFSDLEVDS-DGPTVRVVVANVGPRAGREVVQVYVSKPDSQISRPP
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1080|M.ulcerans_Agy99 LRLLGFERVELEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVG
MMAR_0430|M.marinum_M LRLLGFERVELEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVG
Mb0192|M.bovis_AF2122/97 LRLLGFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVG
Rv0186|M.tuberculosis_H37Rv LRLLGFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVG
MAV_4994|M.avium_104 LRLLGFERVELGPGESRHVTIDADPRLLAHYDGSIRSWRIAAGSHTVALG
MSMEG_2556|M.smegmatis_MC2_155 RWLAGFGSLSLESGERRTLEIPIRRTDLAFWEIRSGQWGVEPGDYTVSVG
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1080|M.ulcerans_Agy99 ASAAALSAVAEAELAGRTFGR-----------------------------
MMAR_0430|M.marinum_M ASAAALSAVAEVELAGRTFGR-----------------------------
Mb0192|M.bovis_AF2122/97 ASAVALKLAAKVKLAGRGFGR-----------------------------
Rv0186|M.tuberculosis_H37Rv ASAVALKLAAKVKLAGRGFGR-----------------------------
MAV_4994|M.avium_104 ISATTLRSTATVELTARTFGR-----------------------------
MSMEG_2556|M.smegmatis_MC2_155 ASSRDLRLHATVTVEGDVPRAVFTRESTLGEILADPAAAPLLFETLGTAA
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1080|M.ulcerans_Agy99 -----------------------------------------------
MMAR_0430|M.marinum_M -----------------------------------------------
Mb0192|M.bovis_AF2122/97 -----------------------------------------------
Rv0186|M.tuberculosis_H37Rv -----------------------------------------------
MAV_4994|M.avium_104 -----------------------------------------------
MSMEG_2556|M.smegmatis_MC2_155 QDAPAMGTDLLRMLESVPIERMVALSGGKVTPERLDDLLAALNAVRP
MAB_4458c|M.abscessus_ATCC_199 -----------------------------------------------