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VSSSGHNAPADVRARQVESEMTDEERFSLLLGVMGAGDLWPLRDERIPADVPMSAGYVPGIARLGVPALL MSDAGLGVTNPGYRPGDTATALPAGLALAASFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNG RNFEYLSEDPFLTAAMVAESIIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRESDLLAFEIAIE RAQPGAVMAAYNKVNGVYAAANGELINEVLKGAWGYRGWVMSDWGGTPGWECALGGLDQECGAQIDAILW QSEAFGDPLRAAYHEGRLPKARLSEMVRRILRSMFAVGVDRWEPAPAPDMDAHDEVAAEIARQGIVLLQN RGVLPLTPAPGTRIAVIGGYAQLGVVAGYGSSAVVPPGGYAEVIPIGGAGLTAGVRNLYLLGSSPLDELR TQFGNAELEFDPGINPAEAVAVARRADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVL ETGNPVAMPWQDSVNAIVQAWYPGQAGARVIAEVLAGRVNPCGRLPITFPVGLGQTPRPELPGYGAPVGA PMRIHYREGADIGYRWFATTGEVPNFAFGHGLTYTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQV YLTAVTGEPRLRLLGFERVELEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVGASAAALSAVA EVELAGRTFGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0430 | bglS | - | 100% (711) | beta-glucosidase BglS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0192 | bglS | 0.0 | 79.59% (691) | beta-glucosidase BGLS |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0186 | bglS | 0.0 | 79.74% (691) | beta-glucosidase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4458c | - | 1e-05 | 24.38% (242) | putative secreted hydrolase |
| M. avium 104 | MAV_4994 | - | 0.0 | 77.60% (701) | glycosyl hydrolase family protein 3 |
| M. smegmatis MC2 155 | MSMEG_2556 | - | 5e-84 | 34.41% (680) | beta-glucosidase |
| M. thermoresistible (build 8) | TH_1910 | lpqI | 7e-06 | 24.92% (329) | PROBABLE CONSERVED LIPOPROTEIN LPQI |
| M. ulcerans Agy99 | MUL_1080 | bglS | 0.0 | 98.84% (691) | beta-glucosidase BglS |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0430|M.marinum_M MSSSGHNAPADVRARQVESEMTDEERFSLLLGVMGAGDLWPLRDERIPAD
MUL_1080|M.ulcerans_Agy99 --------------------MTDEERFSLLLGVMGAGDLWPLRDERIPAD
Mb0192|M.bovis_AF2122/97 --------------------MTDDERFSLLVGLTGASDLWPVRDERIPQG
Rv0186|M.tuberculosis_H37Rv --------------------MTDDERFSLLVGLTGASDLWPVRDERIPQG
MAV_4994|M.avium_104 ------MKDPDERARTVEAQMTDDERFSLLVAVMGAGDMWPVRDERIPAD
MSMEG_2556|M.smegmatis_MC2_155 --------------------MTDPLAHAPTLTLTQQAALGSGASFWTTEA
MAB_4458c|M.abscessus_ATCC_199 ------------------------------------MRAGTVLTGLVVAA
TH_1910|M.thermoresistible__bu -----------------------------------LTLACSPAAERPAEP
.
MMAR_0430|M.marinum_M VPMSAGYVPGIARLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
MUL_1080|M.ulcerans_Agy99 VPMSAGYVPGIARLGVPALLMTDAGLGVTNPGYRPGDTATALPAGLALAA
Mb0192|M.bovis_AF2122/97 VPMCAGYVPGIPRLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
Rv0186|M.tuberculosis_H37Rv VPMCAGYVPGIPRLGVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAA
MAV_4994|M.avium_104 VPMSAGYVPGVPRLGVPPLLMSDAGLGVTNPGYRPGDTATALPAGLALAA
MSMEG_2556|M.smegmatis_MC2_155 VGHIPSIVLTDGPHGVRRQSGASDHLGVGGS-----EPATCFPPAVALSQ
MAB_4458c|M.abscessus_ATCC_199 LTACGGNASEPSKENTSSTKAQAP--------------------------
TH_1910|M.thermoresistible__bu EPDPPAVVATPAATPLSTPLPAAP--------------------------
. .
MMAR_0430|M.marinum_M SFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
MUL_1080|M.ulcerans_Agy99 SFNPALARSAGEVIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
Mb0192|M.bovis_AF2122/97 SFNPVLARSSGKAIGREARSRGFNVQLAGAINLARDPRNGRNFEYLSEDP
Rv0186|M.tuberculosis_H37Rv SFNPVLARSSGKAIGREARSRGFNVQLAGAINLARDPRNGRNFEYLSEDP
MAV_4994|M.avium_104 TFDPALARAAGELIGREARSRGFNVQLAGAMNLARDPRNGRNFEYLSEDP
MSMEG_2556|M.smegmatis_MC2_155 TWDPDLVERVGAALGAEARALGVHVLLGPGVNIKRDPRCGRNFEYFSEDP
MAB_4458c|M.abscessus_ATCC_199 ---ATAAPAAD--LACLSTRDRLAQLLMVGIKDADDAR-----------A
TH_1910|M.thermoresistible__bu ---PAGCGDAQSVLASMELRDKLAQLLMVGVNGAADAR-----------A
. :. . * .:: *.* .
MMAR_0430|M.marinum_M FLTAAMVAESIIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRES
MUL_1080|M.ulcerans_Agy99 FLTAAMVAESIIGIQQQGVISTVKHFSLNCNETNRHWLDAVIDPDAHRES
Mb0192|M.bovis_AF2122/97 LLSATMAAESIIGIQQQGVIATTKHFSLNCNETNRHWLDAVIDPDAHRES
Rv0186|M.tuberculosis_H37Rv LLSATMAAESIIGIQQQGVIATTKHFSLNCNETNRHWLDAVIDPDAHRES
MAV_4994|M.avium_104 LLTAAMVAESVAGIQQQGVISTVKHYSLNCNETNRHFLDAVIDPDAHRES
MSMEG_2556|M.smegmatis_MC2_155 LLSGVLGAAWVRGVQGRGVGASLKHFAVNNSEHDRMRASSDVDARTLREI
MAB_4458c|M.abscessus_ATCC_199 LVRDHHVGGIFVGSWTKKEMLTDGSLHDVIT-AGPIPAAVSIDEEGGRVS
TH_1910|M.thermoresistible__bu VVNDHRVGGIFVGSWSDLSMLSDGSVADIAASAGPFPLAVSVDEEGGRVS
.: . . * : . :* *
MMAR_0430|M.marinum_M DLLAFEIAIERAQPGAVMAAYNKVNGVYAAANGELINEVLKGAWGYRGWV
MUL_1080|M.ulcerans_Agy99 DLLAFEIAIERAQPGAVVAAYNKVNGVYATANGELINEVLKGAWGYRGWV
Mb0192|M.bovis_AF2122/97 DLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLNDVLKGAWGYRGWV
Rv0186|M.tuberculosis_H37Rv DLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLNDVLKGAWGYRGWV
MAV_4994|M.avium_104 DLLAFELAIERAQPGAVMTAYNKVNGVYAAANSVLLNDVLKDAWAYRGWV
MSMEG_2556|M.smegmatis_MC2_155 YLRAFEHVVREAAPWTVMCSNNRINGVYASENTWLLTDVLRGEWGFDGVV
MAB_4458c|M.abscessus_ATCC_199 RLKDLIGPAPSARELAATQTPEQVQALSQERAQKMKDLGITIDFAPDADV
TH_1910|M.thermoresistible__bu RLSGLIGPQPSPRSLARTRSPEEVQVIARERGQAMRGRGITIDFAPVVDV
* : . : : :.:: : : :. *
MMAR_0430|M.marinum_M MSDWGGTPGWECALGGLDQECGAQIDAILWQSEAFGDPLRAAYHEGRLPK
MUL_1080|M.ulcerans_Agy99 MSDWGGTPGWECALGGLDQECGAQIDAILWQSEAFGDPLRAAYHEGRLPK
Mb0192|M.bovis_AF2122/97 MSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADGNLPK
Rv0186|M.tuberculosis_H37Rv MSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADGNLPK
MAV_4994|M.avium_104 MSDWGATPGWECALGGLDQECGAQIDALLWQAESFGAPLRDAYADGRLPK
MSMEG_2556|M.smegmatis_MC2_155 VSDWGAVRDRVAAVA-------AGLDLEMPSSGGFGDAEVVAAVTAGALD
MAB_4458c|M.abscessus_ATCC_199 TD--------------------GDPDGAIGDRSFSGDPQKVAEYAEASVR
TH_1910|M.thermoresistible__bu TD--------------------AADNSVIGDRSFGADPETVTAYAGAYAR
. . : : . :
MMAR_0430|M.marinum_M ARLSEMVRRILRSMFAVGVDRWEPAPAPDM----DAHDEVAAEIARQGIV
MUL_1080|M.ulcerans_Agy99 ARLSEMVRRILRSMFAVGVDRWEPAPAPDM----DAHDEVAAEIARQGIV
Mb0192|M.bovis_AF2122/97 GRLSDMVRRILRSMFAVGIDRWKPAPAPDM----NAHNEIAAQMARQGIV
Rv0186|M.tuberculosis_H37Rv GRLSDMVRRILRSMFAVGIDRWKPAPAPDM----NAHNEIAAQMARQGIV
MAV_4994|M.avium_104 DRLSDMVRRILRSIFAVGVDRSDRAPAPDL----NAHNDIALRIARQGIV
MSMEG_2556|M.smegmatis_MC2_155 ARAVTTAAERVAGLAVRAYESHSAAGHFDIGELTEAHHRLACEAAAQAVV
MAB_4458c|M.abscessus_ATCC_199 GYQAGGVRAVVKHFPGHGHAS---------------GDSHTNGVVTPPLE
TH_1910|M.thermoresistible__bu GLREGGVMPVLKHFPGHGRAS---------------GDSHASGVVTPPLA
. : : . . : . :
MMAR_0430|M.marinum_M LLQN--RGVLPLTPAPGTRIAVIGGYAQLGVVAGYGSSAVVPPGGYAEVI
MUL_1080|M.ulcerans_Agy99 LLQN--RGVLPLRPAPGTRIAVIGGYAQLGVLAGYGSSAVVPPGGYAEVI
Mb0192|M.bovis_AF2122/97 LLQN--RGLLPLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVI
Rv0186|M.tuberculosis_H37Rv LLQN--RGLLPLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVI
MAV_4994|M.avium_104 LLTN--RGLLPLRPDSPARIAVIGGYAQLGVPAGFGSSTVVPAGGYAAVV
MSMEG_2556|M.smegmatis_MC2_155 LLKNDLRDGEPILPLAPSRLAVIGPFAEEPRHQGGGSSHVNPTRLDIPLD
MAB_4458c|M.abscessus_ATCC_199 QLKD--NDLVPYRSLVTSGAAVMIGHMQVPGLTGDDPASLSG----AAVD
TH_1910|M.thermoresistible__bu DLEA--TDLVPYRALVGEQVAVMVGHLQVPGLTGGEPASLSP----DAYR
* . * . **: . . * .: :
MMAR_0430|M.marinum_M PIGGAGLTAGVRNLYLLGSSPLDELRTQFGNAELEFDPGINPAEAVAVAR
MUL_1080|M.ulcerans_Agy99 PIGGAGLTPGVRNLYLLGSSPLDELRTQFGNAELEFDPGINPAEAVAVAR
Mb0192|M.bovis_AF2122/97 PIGGSGLAAGLRNLYLLPSSPLSELRKRLPNAQFEFDPGINPAEAVLAAR
Rv0186|M.tuberculosis_H37Rv PIGGSGLAAGLRNLYLLPSSPLSELRKRLPNAQFEFDPGINPAEAVLAAR
MAV_4994|M.avium_104 PIGGTALEAGLRNLYLLPSSPLQELRKLLPENTIDFDPGISPAEAVAAAQ
MSMEG_2556|M.smegmatis_MC2_155 EIRARNGDQAATHFPGLPTDSGQDSEQVR----------AEAVRGAAEAE
MAB_4458c|M.abscessus_ATCC_199 LLRKGTGYGAPAYDGVIFTDDLSS--------------------------
TH_1910|M.thermoresistible__bu LLRS------MGYHGPVFTDDLSG--------------------------
: : :. .
MMAR_0430|M.marinum_M RADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVLETGN
MUL_1080|M.ulcerans_Agy99 RADVAVVFAIRAEGEGFDSADLTLPWGQDAVISAVAAANPNTVVVLEGGN
Mb0192|M.bovis_AF2122/97 RADIAIVFAIRAEGEGFDSADLSLPWGQDALIAAVASANANTVVVLETGN
Rv0186|M.tuberculosis_H37Rv RADIAIVFAIRAEGEGFDSADLSLPWGQDALIAAVASANANTVVVLETGN
MAV_4994|M.avium_104 RADIAIVFAVRAEGEGFDLADLSLPSGQDELIGAVAAANPNTVVVLQTGN
MSMEG_2556|M.smegmatis_MC2_155 AAVLFLGLTADEESEGYDREHIDLPQAQLALLRAVVEVQPRTVVVLSHGG
MAB_4458c|M.abscessus_ATCC_199 ---------MAAITDRFPIEEAVLKSIKAGVDWALWVSTEKVGSVLDR--
TH_1910|M.thermoresistible__bu ---------MRAITDRYGVAEAVLRSLQAGADVALWLTTAEVPAVLDR--
: : . * : *: .. **.
MMAR_0430|M.marinum_M PVAMPWQDSVN-AIVQAWYPGQAGARVIAEVLAGRVNPCGRLPITFPVGL
MUL_1080|M.ulcerans_Agy99 PVAMPWQDSVN-AIVQAWYPGQAGARVIAEVLAGRVNPCGRLPITFPVGL
Mb0192|M.bovis_AF2122/97 PVTMPWRDSVN-AIMQAWYPGQAGGQAVAEIVTGQVNPSGRLPITFPVDL
Rv0186|M.tuberculosis_H37Rv PVTMPWRDSVN-AIMQAWYPGQAGGQAVAEIVTGQVNPSGRLPITFPVDL
MAV_4994|M.avium_104 PVTMPWLGAVN-AVVQAWYPGQAGATAIAEVLTGRVNPGGRLPITFPVDL
MSMEG_2556|M.smegmatis_MC2_155 VVRLDEVAKHAPAILDGALLGQAGGGAVADVLFGAVNPSGRLAETVPVRL
MAB_4458c|M.abscessus_ATCC_199 -------------LESAYNAGELNADAINASVRRVLAYKG-VPACG----
TH_1910|M.thermoresistible__bu -------------LEAAVAAGELSEARVDESVLRLAGAKGYTPRC-----
: . *: . : : * .
MMAR_0430|M.marinum_M GQTPRPELPGYGAPVGAPMRIHYREGADIGYRWFATTGEVPNFAFGHGLT
MUL_1080|M.ulcerans_Agy99 GQTPRPELPGYGAPVGAPMRIHYREGADIGYRWFATTGEVPNFAFGHGLT
Mb0192|M.bovis_AF2122/97 GQTPRSQPRELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMFAFGHGLS
Rv0186|M.tuberculosis_H37Rv GQTPRSQPPELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMFAFGHGLS
MAV_4994|M.avium_104 HQTPRPQLPGAGLPWGTPSTIDYVEGADVGYRWFAAKGHVPMFAFGHGLS
MSMEG_2556|M.smegmatis_MC2_155 QDCP-----AFLNFPSENGHTVYGERVFVGYRWYDARALEVTFPFGHGLS
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1910|M.thermoresistible__bu --------------------------------------------------
MMAR_0430|M.marinum_M YTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQVYLTAVTG---EPR
MUL_1080|M.ulcerans_Agy99 YTSFGYRDLAVSGGDTVTVTFGVANTGDRSGADVPQVYLTAVTG---EPR
Mb0192|M.bovis_AF2122/97 YTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPG---ESR
Rv0186|M.tuberculosis_H37Rv YTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPG---ESR
MAV_4994|M.avium_104 YTRFEHRDLVVRGGDTITAGFTVVNTGDRAGADVPQLYLTAMPG---KPC
MSMEG_2556|M.smegmatis_MC2_155 YTAFAFSDLEVDS-DGPTVRVVVANVGPRAGREVVQVYVSKPDSQISRPP
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1910|M.thermoresistible__bu --------------------------------------------------
MMAR_0430|M.marinum_M LRLLGFERVELEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVG
MUL_1080|M.ulcerans_Agy99 LRLLGFERVELEPGQSCAVEIVADPRLLACYDGAAGCWRIEAGTYTVAVG
Mb0192|M.bovis_AF2122/97 LRLLGFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVG
Rv0186|M.tuberculosis_H37Rv LRLLGFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVG
MAV_4994|M.avium_104 LRLLGFERVELGPGESRHVTIDADPRLLAHYDGSIRSWRIAAGSHTVALG
MSMEG_2556|M.smegmatis_MC2_155 RWLAGFGSLSLESGERRTLEIPIRRTDLAFWEIRSGQWGVEPGDYTVSVG
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1910|M.thermoresistible__bu --------------------------------------------------
MMAR_0430|M.marinum_M ASAAALSAVAEVELAGRTFGR-----------------------------
MUL_1080|M.ulcerans_Agy99 ASAAALSAVAEAELAGRTFGR-----------------------------
Mb0192|M.bovis_AF2122/97 ASAVALKLAAKVKLAGRGFGR-----------------------------
Rv0186|M.tuberculosis_H37Rv ASAVALKLAAKVKLAGRGFGR-----------------------------
MAV_4994|M.avium_104 ISATTLRSTATVELTARTFGR-----------------------------
MSMEG_2556|M.smegmatis_MC2_155 ASSRDLRLHATVTVEGDVPRAVFTRESTLGEILADPAAAPLLFETLGTAA
MAB_4458c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1910|M.thermoresistible__bu --------------------------------------------------
MMAR_0430|M.marinum_M -----------------------------------------------
MUL_1080|M.ulcerans_Agy99 -----------------------------------------------
Mb0192|M.bovis_AF2122/97 -----------------------------------------------
Rv0186|M.tuberculosis_H37Rv -----------------------------------------------
MAV_4994|M.avium_104 -----------------------------------------------
MSMEG_2556|M.smegmatis_MC2_155 QDAPAMGTDLLRMLESVPIERMVALSGGKVTPERLDDLLAALNAVRP
MAB_4458c|M.abscessus_ATCC_199 -----------------------------------------------
TH_1910|M.thermoresistible__bu -----------------------------------------------