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RAGTVLTGLVVAALTACGGNASEPSKENTSSTKAQAPATAAPAADLACLSTRDRLAQLLMVGIKDADDAR ALVRDHHVGGIFVGSWTKKEMLTDGSLHDVITAGPIPAAVSIDEEGGRVSRLKDLIGPAPSARELAATQT PEQVQALSQERAQKMKDLGITIDFAPDADVTDGDPDGAIGDRSFSGDPQKVAEYAEASVRGYQAGGVRAV VKHFPGHGHASGDSHTNGVVTPPLEQLKDNDLVPYRSLVTSGAAVMIGHMQVPGLTGDDPASLSGAAVDL LRKGTGYGAPAYDGVIFTDDLSSMAAITDRFPIEEAVLKSIKAGVDWALWVSTEKVGSVLDRLESAYNAG ELNADAINASVRRVLAYKGVPACG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4458c | - | - | 100% (375) | putative secreted hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0243 | lpqI | 1e-107 | 54.81% (374) | lipoprotein LpqI |
| M. gilvum PYR-GCK | Mflv_0415 | - | 1e-105 | 58.23% (328) | Beta-N-acetylhexosaminidase |
| M. tuberculosis H37Rv | Rv0237 | lpqI | 1e-107 | 55.08% (374) | lipoprotein LpqI |
| M. leprae Br4923 | MLBr_02569 | - | 1e-114 | 56.96% (381) | putative secreted glycosyl hydrolase |
| M. marinum M | MMAR_0499 | lpqI | 1e-112 | 59.89% (359) | lipoprotein LpqI |
| M. avium 104 | MAV_4920 | - | 1e-113 | 56.81% (382) | glycosyl hydrolase family protein 3 |
| M. smegmatis MC2 155 | MSMEG_0361 | - | 1e-114 | 57.29% (377) | glycosyl hydrolase family protein 3 |
| M. thermoresistible (build 8) | TH_1910 | lpqI | 1e-105 | 56.94% (353) | PROBABLE CONSERVED LIPOPROTEIN LPQI |
| M. ulcerans Agy99 | MUL_1162 | lpqI | 1e-111 | 58.36% (365) | lipoprotein LpqI |
| M. vanbaalenii PYR-1 | Mvan_0256 | - | 1e-106 | 57.14% (364) | Beta-N-acetylhexosaminidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0243|M.bovis_AF2122/97 ----MAFPRTLAILAAAAALVVACSHGGTPTGSS-----TTSGASP----
Rv0237|M.tuberculosis_H37Rv ----MAFPRTLAILAAAAALVVACSHGGTPTGSS-----TTSGASP----
MMAR_0499|M.marinum_M ----MAFPRTLAVLAAASALVAACSHGGTRTGSSST--TTSAGASPSATS
MUL_1162|M.ulcerans_Agy99 ----MAFPRTLAVLAAASALVAACSHGGTRTGSSST--TTSAGASRSATS
MAV_4920|M.avium_104 ----MALSRPLAAHAAVLAAVSALMIGCAHRAAP-----PPAHSSTS---
MLBr_02569|M.leprae_Br4923 ----MAFPRTLIVLAAASALVVTCGHDVAQAPDS-------ASIVAG---
Mflv_0415|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0256|M.vanbaalenii_PYR-1 MANPRTAPEALVGVLAASALLVGCTSSTAPEPTPHVLHATPSMAAGPALN
TH_1910|M.thermoresistible__bu ------------LTLACSP---AAERPAEPEPDPPAVVATP---AATPLS
MSMEG_0361|M.smegmatis_MC2_155 ----MASPRLLATFVALSGLLLACSPAAPPDAGPSTGPSGSPDMQPMATT
MAB_4458c|M.abscessus_ATCC_199 ------MRAGTVLTGLVVAALTACGGNASEPSKE----------------
Mb0243|M.bovis_AF2122/97 ATPVAVPVPRSCAEPAGIPALLS-PRDKLAQLLVVGVRDAADAQAVVTNY
Rv0237|M.tuberculosis_H37Rv ATPVAVPVPRSCAEPAGIPALLS-PRDKLAQLLVVGVRDAADAQAVVTNY
MMAR_0499|M.marinum_M STPMAAAAPRICADPAAVPAAMPNVRDKLAQLLMVGVRDGDDARAVVTNY
MUL_1162|M.ulcerans_Agy99 STPMAAAAPRICADPAAVPAAMPNVRDKLAQSLMVGVRDGDDARAVVTNY
MAV_4920|M.avium_104 NTPAAAPAPRVCVDPPAAPATLN-LRDKLAQLLMVGVKNADDARNVVNGY
MLBr_02569|M.leprae_Br4923 ELTAAALTPACVDLPASVPGTLS-TRDKLAQLLMVGVRDAADAKAVVTDH
Mflv_0415|M.gilvum_PYR-GCK ---------------------MS-TRDKLAQLLMVGVTGAADARTAAAEY
Mvan_0256|M.vanbaalenii_PYR-1 LPAAPAPAAPACGDPAAIVASMS-TRDKLAQRLMVGVTGAADARAVVDAH
TH_1910|M.thermoresistible__bu TPLPAAPPAG-CGDAQSVLASME-LRDKLAQLLMVGVNGAADARAVVNDH
MSMEG_0361|M.smegmatis_MC2_155 APLPEAP-------ATCDLAALP-ARDKLAQLLTVGVTDAADARAVVADH
MAB_4458c|M.abscessus_ATCC_199 NTSSTKAQAPATAAPAADLACLS-TRDRLAQLLMVGIKDADDARALVRDH
: **:*** * **: .. **: . :
Mb0243|M.bovis_AF2122/97 HVGGILIGSDTDLTIFD-GALAEIVAGGGPLPLAVSVDEEGGRLSRLRSL
Rv0237|M.tuberculosis_H37Rv HVGGILIGSDTDLTIFD-GALAEIVAGGGPLPLAVSVDEEGGRVSRLRSL
MMAR_0499|M.marinum_M RVGGILIGSDTDLSILTNGVLKDIVAGSGPLPVAVSVDEEGGRVSRLKSL
MUL_1162|M.ulcerans_Agy99 RVGGILIGSDTDLSILTNGVLKDIVAGSGPLPVAVNVDEEGGRVSRLKSL
MAV_4920|M.avium_104 HVGGIFIGSWTDLTIFQ-GPLADIAAKAGPLPLAVSVDEEGGRVSRLKSL
MLBr_02569|M.leprae_Br4923 HVGGIMIGSWTDLSMLINGALTDIARNPGPLPLAVSVDEEGGRVSRLKSL
Mflv_0415|M.gilvum_PYR-GCK HVGGIMVGSWTDLSMLTDGSLPDIAN-AGLLPLAVSVDEEGGRVSRLSGL
Mvan_0256|M.vanbaalenii_PYR-1 HVGGIMVGSWTDLSMLSDNSLADIAATAAPLPPAVSVDEEGGRVSRLAGL
TH_1910|M.thermoresistible__bu RVGGIFVGSWSDLSMLSDGSVADIAASAGPFPLAVSVDEEGGRVSRLSGL
MSMEG_0361|M.smegmatis_MC2_155 HVGGIMIGSWTDLSMLTDGSLGDIAASAAPLPLAVSVDEEGGRVSRLASL
MAB_4458c|M.abscessus_ATCC_199 HVGGIFVGSWTKKEMLTDGSLHDVIT-AGPIPAAVSIDEEGGRVSRLKDL
:****::** :. :: . : :: . :* **.:******:*** .*
Mb0243|M.bovis_AF2122/97 IGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAP
Rv0237|M.tuberculosis_H37Rv IGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAP
MMAR_0499|M.marinum_M LGGRGPSARELARTDTVDQVYDVALQRGRKMKELGITVDLAPVVDVTDAP
MUL_1162|M.ulcerans_Agy99 LGGRGPSARELARTDTVDQVYDVALQRGRKMKELGITVDLAPVVDVTDAP
MAV_4920|M.avium_104 IG-TSPSPRELAQTQTVQQVHDLAADRGKKMRDLGITIDFAPVVDVSDEP
MLBr_02569|M.leprae_Br4923 IG-MAPSARVLAQTSTVDQVYDMALDRGHKMRDLGITIDFAPVVDVTDAP
Mflv_0415|M.gilvum_PYR-GCK IG-PQPSARVLAQTKTPDEVRAIARDRGAKMRNLGITVDFAPVVDVSDAP
Mvan_0256|M.vanbaalenii_PYR-1 IG-AQPSPRRLAATSSPEQVYQIALERGRKMRGLGITIDFAPVVDVTDAP
TH_1910|M.thermoresistible__bu IG-PQPSPRSLARTRSPEEVQVIARERGQAMRGRGITIDFAPVVDVTDAA
MSMEG_0361|M.smegmatis_MC2_155 IG-SQPSARELARTKTADEVYGIALDRGRKMRDLGVTVDFAPVVDVTDAA
MAB_4458c|M.abscessus_ATCC_199 IG-PAPSARELAATQTPEQVQALSQERAQKMKDLGITIDFAPDADVTDGD
:* **.* ** * : ::* :: :*. *: *:*:*:** .**:*
Mb0243|M.bovis_AF2122/97 DDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDS
Rv0237|M.tuberculosis_H37Rv DDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDS
MMAR_0499|M.marinum_M DDTVIGDRSFGSNPETVTEYAGAYARGLRDAGLLPVLKHFPGHGRASGDS
MUL_1162|M.ulcerans_Agy99 DDTVIGDRSFGSNPETVTEYAGAYARGLRDAGLLPVLKHFPGHGRASGDS
MAV_4920|M.avium_104 DDAVIGNRSFGADPAKVTEYAGAYAQGLRDAGLLPVLKHFPGHGHGSGDS
MLBr_02569|M.leprae_Br4923 DDSVIGGRSFSSDPAVVTAYAGAYARGLRDAGVLPVLKHFPGHGHGSGDS
Mflv_0415|M.gilvum_PYR-GCK DNTVIGDRSFGADPTTVTDYAGAYAQGLRDAGVLPVLKHFPGHGSGSGDS
Mvan_0256|M.vanbaalenii_PYR-1 DGTVIGDRSFGADPTAVVDYAGAYARGLRDAGVLPVLKHFPGHGSGSGDT
TH_1910|M.thermoresistible__bu DNSVIGDRSFGADPETVTAYAGAYARGLREGGVMPVLKHFPGHGRASGDS
MSMEG_0361|M.smegmatis_MC2_155 ADTVIGDRSFGSDPAVVTEYAGAYARGLRDAGVLPVLKHFPGHGHASGDS
MAB_4458c|M.abscessus_ATCC_199 PDGAIGDRSFSGDPQKVAEYAEASVRGYQAGGVRAVVKHFPGHGHASGDS
. .**.***..:* *. ** * .:* : .*: .*:******* .***:
Mb0243|M.bovis_AF2122/97 HNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASL
Rv0237|M.tuberculosis_H37Rv HNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASL
MMAR_0499|M.marinum_M HTGGVVTPPLSDLQDSDLVPYRTLVTQTPVAVMLGHLQVPGLTGDEPASL
MUL_1162|M.ulcerans_Agy99 HTGGVVTPPLSDLQDSDLVPYRTLVTQTPVAVMLGHLQVPGLTGDEPASL
MAV_4920|M.avium_104 HTGGVVTPPLDDLQNNDLVPYRTLVTTPPVGVMVGHLQVPGLTDDVPASL
MLBr_02569|M.leprae_Br4923 HTGGVTTPPLQDLQTNDLVPYRTLVADAPVGVMLGHLDVPGLTGDDPASL
Mflv_0415|M.gilvum_PYR-GCK HVGSVVAPSLEQLQASDLVPYRTLAAQAPVGVMVGHVEVPGLTGSDPASL
Mvan_0256|M.vanbaalenii_PYR-1 HAGSVVTPPLGDLVARDLVPYRTLTTQGPVGVMVGHMEVPGLTGSEPASL
TH_1910|M.thermoresistible__bu HASGVVTPPLADLEATDLVPYRALVGEQ-VAVMVGHLQVPGLTGGEPASL
MSMEG_0361|M.smegmatis_MC2_155 HTGGVTTPPLDVLMGDDLVPYRTLTGQAPVAVMVGHMQVPGLTGSDPASL
MAB_4458c|M.abscessus_ATCC_199 HTNGVVTPPLEQLKDNDLVPYRSLVTSG-AAVMIGHMQVPGLTGDDPASL
* ..*.:*.* * ******:*. ..**:**::*****.. ****
Mb0243|M.bovis_AF2122/97 SKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQA
Rv0237|M.tuberculosis_H37Rv SKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQA
MMAR_0499|M.marinum_M SKNAVDLLRNGTGYGGPPFDGPIFSDDLSSMAAISDRYGVTEAVLRSLQA
MUL_1162|M.ulcerans_Agy99 SKNAVDLLRNGTGYGGPPFDGPIFSDDLSSMAAISDRYGVTEAVLRSLQA
MAV_4920|M.avium_104 SPEAVQLLRNGVGYKGPPFTGPVFSDDLSSMAAISDRYGVSEAVLRSLLA
MLBr_02569|M.leprae_Br4923 SPAAVQLLRTGANYGAPPFNGPVFSDDVSSMAAISDRYGLADAVLRTLQA
Mflv_0415|M.gilvum_PYR-GCK SPQAYGLLRSG-GYGGPPFGGVVFTDDLSGMQAISDRLGVAEAVLRALQA
Mvan_0256|M.vanbaalenii_PYR-1 SPPAYALLRSG-DYGGPPFGGPVFTDDLSGMQAITDRLGVADAVLRSLQA
TH_1910|M.thermoresistible__bu SPDAYRLLRSM-GYHGP-----VFTDDLSGMRAITDRYGVAEAVLRSLQA
MSMEG_0361|M.smegmatis_MC2_155 SPAAYNLLRSG-GYGGPGFGGLVYTDDLSSMGAINQRYGVADAVLRALQA
MAB_4458c|M.abscessus_ATCC_199 SGAAVDLLRKGTGYGAPAYDGVIFTDDLSSMAAITDRFPIEEAVLKSIKA
* * ***. .* .* :::**:*.* **.:* : :***::: *
Mb0243|M.bovis_AF2122/97 GADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPG
Rv0237|M.tuberculosis_H37Rv GADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPG
MMAR_0499|M.marinum_M GTDIALWVSTEEVPAVLDRLEQALAAGELQMSAVDASLVRVARMKNVSAS
MUL_1162|M.ulcerans_Agy99 GTDIALWVSTEEVPAVLDRLEQALAAGELQMSAVDASLVRVARMKNVSAS
MAV_4920|M.avium_104 GVDVALWVTTDEVPAVLDRLQKAVASGELPAQRVDESLVRVATMKGRGPA
MLBr_02569|M.leprae_Br4923 GTDIALWVSTQTVPAVLDRLEKVVSAGELAMSAVDASVVRVATIKGPGPG
Mflv_0415|M.gilvum_PYR-GCK GADVALWLSTGEVPAVLDRLEKAVGAGELTMSGVDGAVTRIVAMKGPSPR
Mvan_0256|M.vanbaalenii_PYR-1 GADVALWLSTAEVPAVLDRLEQAVAAGELTMPRIDEAVTRVIAMKGPSPR
TH_1910|M.thermoresistible__bu GADVALWLTTAEVPAVLDRLEAAVAAGELSEARVDESVLRLAGAKGYTPR
MSMEG_0361|M.smegmatis_MC2_155 GADNALWITTAEVPAVLDRLEQALASGELNQGAVDASLQRNAAVKGP-LR
MAB_4458c|M.abscessus_ATCC_199 GVDWALWVSTEKVGSVLDRLESAYNAGELNADAINASVRRVLAYKGV-PA
*.* ***::* * :*****: . :*** :: :: * *.
Mb0243|M.bovis_AF2122/97 CGR
Rv0237|M.tuberculosis_H37Rv CGR
MMAR_0499|M.marinum_M CGH
MUL_1162|M.ulcerans_Agy99 CGH
MAV_4920|M.avium_104 CGH
MLBr_02569|M.leprae_Br4923 CGR
Mflv_0415|M.gilvum_PYR-GCK CGG
Mvan_0256|M.vanbaalenii_PYR-1 CGG
TH_1910|M.thermoresistible__bu C--
MSMEG_0361|M.smegmatis_MC2_155 CG-
MAB_4458c|M.abscessus_ATCC_199 CG-
*