For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PAPETDSDARSSASPAAGKPNLGRFGSFGRGVTPAQARDIEALGYGAVWVGGSPPAELAWVEPILAATTT LQVATGIVNIWSAPAKPVAESFHRIEAAYPGRFLLGIGVGHPEAITEYHSTGNAVDALIEYLNRLDDYGV PANRRVVAALGPRVLRLAARRSAGAHPYLTTPEHTGAARELIGPSAFLAPEHKVVLTTDAQRARAVGRKA LDIYLNLANYLNSWKRLGFSERDIARPGSDRLVDAVVAYGTPAAIAARLNEHLQAGADHVPVQVLTKSEN LVPALAELAGPLGLAGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0842 | - | - | 100% (298) | hypothetical protein MUL_0842 |
| M. ulcerans Agy99 | MUL_0841 | - | 1e-96 | 63.21% (280) | hypothetical protein MUL_0841 |
| M. ulcerans Agy99 | MUL_4481 | - | 7e-05 | 36.05% (86) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 1e-128 | 80.28% (284) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5005 | - | 1e-125 | 78.25% (285) | hypothetical protein Mflv_5005 |
| M. tuberculosis H37Rv | Rv3463 | - | 1e-128 | 80.28% (284) | hypothetical protein Rv3463 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3778 | - | 1e-93 | 62.32% (276) | hypothetical protein MAB_3778 |
| M. marinum M | MMAR_1084 | - | 1e-167 | 97.99% (298) | hypothetical protein MMAR_1084 |
| M. avium 104 | MAV_4404 | - | 1e-133 | 84.59% (279) | hypothetical protein MAV_4404 |
| M. smegmatis MC2 155 | MSMEG_1514 | - | 1e-124 | 77.27% (286) | hypothetical protein MSMEG_1514 |
| M. thermoresistible (build 8) | TH_0027 | - | 1e-95 | 64.18% (268) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_1368 | - | 1e-128 | 81.88% (276) | hypothetical protein Mvan_1368 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0842|M.ulcerans_Agy99 ----MPAPETDSDARSSASPAAGK-PNLGRFGSFGRG-VTPAQARDIEAL
MMAR_1084|M.marinum_M ----MPDPETDSDARSSASPVAGK-PNLGRFGSFGRG-VTPAQARDIEAL
Mb3492|M.bovis_AF2122/97 ----MTN-------CAAGKPSSG--PNLGRFGSFGRG-VTPQQATEIEAL
Rv3463|M.tuberculosis_H37Rv ----MTN-------CAAGKPSSG--PNLGRFGSFGRG-VTPQQATEIEAL
MAV_4404|M.avium_104 -----------------MTQAAGK-PDLGRFGSFGRG-VTPQQAKDIEAL
Mflv_5005|M.gilvum_PYR-GCK --------------MSDVT------PDLGRFGSFGRG-VTPEQAQQIEAL
Mvan_1368|M.vanbaalenii_PYR-1 --------------MTDTK------PDLGRFGSFGRG-VTPQQAKDIEAL
MSMEG_1514|M.smegmatis_MC2_155 MTGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFGRG-VTPAQAKEIEAL
MAB_3778|M.abscessus_ATCC_1997 --------------MGESK--------LNRYGVWKGGPVTPEQARTIEDL
TH_0027|M.thermoresistible__bu --------------MTDAVSLK---PDLGRFGVWTGGPIPRELAAEIEKL
*.*:* : * :. * ** *
MUL_0842|M.ulcerans_Agy99 GYGAVWVGGSPPAELAWVEPILAATTTLQVATGIVNIWSAPAKPVAESFH
MMAR_1084|M.marinum_M GYGAVWVGGSPPAELAWVEPILAATTTLQVATGIVNIWSAPAKPVAESFH
Mb3492|M.bovis_AF2122/97 GYGAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
Rv3463|M.tuberculosis_H37Rv GYGAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFH
MAV_4404|M.avium_104 GYGAVWVGGSPPAELAWVEPLLEATTTLQVATGIVNIWTAPAGPVAESFH
Mflv_5005|M.gilvum_PYR-GCK GYGAVWVGGSPPAELDWVEPLLAATTTLQVATGIVNIWTADAGPVAESFH
Mvan_1368|M.vanbaalenii_PYR-1 GYGAVWVGGSPPAELDWVEPLLDATTTLQVATGIVNIWTAAAGPVAESFH
MSMEG_1514|M.smegmatis_MC2_155 GYGAVWVGGSPPAELEWVEPILEATTTLQVATGIVNIWTAAPGPVAESFH
MAB_3778|M.abscessus_ATCC_1997 GYGSVWVGGVFTADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAAFH
TH_0027|M.thermoresistible__bu GYRALWVGGSPAAELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFH
** ::**** .* * :***:* .* .* **:******:: :* :**
MUL_0842|M.ulcerans_Agy99 RIEAAYPGRFLLGIGVGHPEAITEYHSTGNAVDALIEYLNRLDDYGVPAN
MMAR_1084|M.marinum_M RIEAAYPGRFLLGIGVGHPEAITEYHSTSNAVDALIEYLNRLDDYGVPAN
Mb3492|M.bovis_AF2122/97 RIEAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPAN
Rv3463|M.tuberculosis_H37Rv RIEAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPAN
MAV_4404|M.avium_104 RIEAAYPGRFLLGIGVGHPEAHTEYR---KPYDALADYLTRLDQYGVPAG
Mflv_5005|M.gilvum_PYR-GCK RIESAHPGRFLLGIGVGHPEAHQQYR---RPIDALVEYLDKLDEYGVPRG
Mvan_1368|M.vanbaalenii_PYR-1 RIEAAHPGRFLLGIGVGHPEAHQEYV---KPLDALTDYLDKLDEYGVPRG
MSMEG_1514|M.smegmatis_MC2_155 RIEAACPGRFLLGIGVGHREAHVEYR---KPLDALTDYLDKLDSYGVPKH
MAB_3778|M.abscessus_ATCC_1997 RIEAAYPGRFLLGVGAGHPEASAEYR---KPYDALVEYLDGLDAAGVPKE
TH_0027|M.thermoresistible__bu RIEKAYPGRFVLGLGVGHPEATEEYA---KPYEAMVTYLDVLDEATVPTS
*** * ****:**:*.** * :* .. :*: ** ** **
MUL_0842|M.ulcerans_Agy99 RRVVAALGPRVLRLAARRSAGAHPYLTTPEHTGAARELIGPSAFLAPEHK
MMAR_1084|M.marinum_M RRVVAALGPRVLRLAARRSAGAHPYLTTPEHTAAARELIGPSAFLAPEHK
Mb3492|M.bovis_AF2122/97 RRVVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
Rv3463|M.tuberculosis_H37Rv RRVVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
MAV_4404|M.avium_104 RRVVAALGPRVLRLSAERSAGAHPYLTTPEHTARARELIGPSAFLAPEHK
Mflv_5005|M.gilvum_PYR-GCK RRVVAALGPKVLKLSADRAAGAHPYLTTPEHTARARELIGPEAFLAPEHK
Mvan_1368|M.vanbaalenii_PYR-1 RRVVAALGPKVLQLSATRAAGAHPYLTTPEHTARARELIGPEALLAPEHK
MSMEG_1514|M.smegmatis_MC2_155 RRVVAALGPKVLQLSAEHSAGAHPYLTTPEHTRSAREIIGPDAFLAPEHK
MAB_3778|M.abscessus_ATCC_1997 RRVLAALGPKVLKLSADRTAGAHPYLTTPEHTRQAREIIGPDALLVPEHK
TH_0027|M.thermoresistible__bu RRVLAALGPRMLQLAAQRSAGAHPYLTTPQHTGQARNRIGPSVFLAPEHK
***:*****::* *:* ::**********:** **: ***..:*.****
MUL_0842|M.ulcerans_Agy99 VVLTTDAQ----------RARAVGRKALDIYLNLANYLNSWKRLGFSERD
MMAR_1084|M.marinum_M VVLTTDAQ----------RARAVGRKALDIYLNLANYLNSWKRLGFCERD
Mb3492|M.bovis_AF2122/97 VVLTTDSA----------RARTVGRQALDMYFNLANYRNNWKRLGFTDDE
Rv3463|M.tuberculosis_H37Rv VVLTTDSA----------RARTVGRQALDMYFNLANYRNNWKRLGFTDDE
MAV_4404|M.avium_104 VVLTTDAE----------HARAVGRKALDIYFNLANYRNNWKRLGFTDDE
Mflv_5005|M.gilvum_PYR-GCK VVLTTDERSREEHVTDPDRAREVGRKALEIYLDLANYLNSWKRLGFSDED
Mvan_1368|M.vanbaalenii_PYR-1 VVLTTDAK----------QAREVGRKALDIYLNLANYLNNWKRLGFGDQD
MSMEG_1514|M.smegmatis_MC2_155 VVLTTDAE----------QARAVGRKALDLYLGLANYLNNFKRLGFTDDE
MAB_3778|M.abscessus_ATCC_1997 VVLSTDAP----------SAREIGRRTVDFYLTLSNYVNNWKRLGFNDED
TH_0027|M.thermoresistible__bu VVLDTDAA----------AAREIGRQTIGFYLRLRNYVNNWKQLGFTDDD
*** ** ** :**::: :*: * ** *.:*:*** : :
MUL_0842|M.ulcerans_Agy99 IARPGSDRLVDAVVAYGTPAAIAARLNEHLQAGADHVPVQVLTKSENLVP
MMAR_1084|M.marinum_M IARPGSDRLVDAVVAYGTPAAIAARLNEHLQAGADHVPVQVLTKSENLVP
Mb3492|M.bovis_AF2122/97 VSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTEDDNLVS
Rv3463|M.tuberculosis_H37Rv VSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTEDDNLVS
MAV_4404|M.avium_104 ITRPGSDRLVDALVAYGSVDRIAARLREHLDAGADHVPVQVLTKDENLVS
Mflv_5005|M.gilvum_PYR-GCK VAKPGSDRLVDAVVAYGTAEQIAARLREHLDAGADHVPVQVLTGSDKLVP
Mvan_1368|M.vanbaalenii_PYR-1 VAKPGSDRLVDAVVAYGTVDAIAARLTEHLDAGADHVPVQVLTGSEKLVP
MSMEG_1514|M.smegmatis_MC2_155 LAKPGADRFIDAVVAYGTVDAIAARLSEHLAAGADHVPVQVLTSPDKLVP
MAB_3778|M.abscessus_ATCC_1997 LTSPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVLIQVLG-DKGLVD
TH_0027|M.thermoresistible__bu IAEPGSDELIDAMVAHGTAEQVADALREHLDRGADHVAIQVLGGRERLLP
:: **:* ::**:**:*: :* * *** ***:* :*** . *:
MUL_0842|M.ulcerans_Agy99 ALA----------------------------ELAGPLGLAGA----
MMAR_1084|M.marinum_M ALA----------------------------ELAGPLGLTGA----
Mb3492|M.bovis_AF2122/97 ALT----------------------------ELAKPLRLT------
Rv3463|M.tuberculosis_H37Rv ALT----------------------------ELAKPLRLT------
MAV_4404|M.avium_104 ALA----------------------------ELAGPLGLKPS----
Mflv_5005|M.gilvum_PYR-GCK ALA----------------------------ELAGPLGLESTEEQR
Mvan_1368|M.vanbaalenii_PYR-1 ALA----------------------------ELAGPLGLQRKG---
MSMEG_1514|M.smegmatis_MC2_155 ALA----------------------------ELAGPLGLA------
MAB_3778|M.abscessus_ATCC_1997 TLT----------------------------SLADALR--------
TH_0027|M.thermoresistible__bu TLXXSPRCGPNWGRCTSWSRARVWWTSPRSPRSAGRPGSGSSM---
:* *