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M. thermoresistible (build 8) TH_0027 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 68604 - 69545
length: 314

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0027-100% (314)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_2753-4e-5444.66% (253) PUTATIVE conserved hypothetical protein
M. thermoresistible (build 8)TH_2809-3e-0924.37% (279) PUTATIVE conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3492-3e-9664.77% (264) hypothetical protein Mb3492
M. gilvum PYR-GCKMflv_5006-1e-10970.11% (271) hypothetical protein Mflv_5006
M. tuberculosis H37RvRv3463-3e-9664.77% (264) hypothetical protein Rv3463
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3778-5e-9765.10% (255) hypothetical protein MAB_3778
M. marinum MMMAR_1083-1e-10470.34% (263) hypothetical protein MMAR_1083
M. avium 104MAV_4404-1e-10065.81% (272) hypothetical protein MAV_4404
M. smegmatis MC2 155MSMEG_1513-1e-11372.06% (272) hypothetical protein MSMEG_1513
M. ulcerans Agy99MUL_0841-2e-9968.06% (263) hypothetical protein MUL_0841
M. vanbaalenii PYR-1Mvan_1367-1e-11170.11% (271) hypothetical protein Mvan_1367

CLUSTAL 2.0.9 multiple sequence alignment


TH_0027|M.thermoresistible__bu      MTD--AVSLK--PDLGRFGVWTGG-PIPRELAAEIEKLGYRALWVGGSPA
MSMEG_1513|M.smegmatis_MC2_155      MTD--ALSLK--PNLGRYGVWTAG-AVTPKQAAEIEKLGYGAVWIGGSPA
MMAR_1083|M.marinum_M               MTN--AVSLK--PELGRFGVWLGSRSITPELAGQIESLGYGAAWIGASPD
MUL_0841|M.ulcerans_Agy99           MTN--AVSLK--PELGRFGVWLGSRSITPELAGQIESLAYGAAWIGASPD
Mflv_5006|M.gilvum_PYR-GCK          MTNSEGPSLK--PALGRFGVWTGE-PATPDQAVEIEKLGYGTVWVGASPA
Mvan_1367|M.vanbaalenii_PYR-1       MTASEGPSLK--PALGRFGVWTGA-PVSPDQAVEIEKLGYGTVWVGASPA
Mb3492|M.bovis_AF2122/97            MTNCAAGKPSSGPNLGRFGSFGRG--VTPQQATEIEALGYGAVWVGGSPP
Rv3463|M.tuberculosis_H37Rv         MTNCAAGKPSSGPNLGRFGSFGRG--VTPQQATEIEALGYGAVWVGGSPP
MAV_4404|M.avium_104                MT-QAAGK----PDLGRFGSFGRG--VTPQQAKDIEALGYGAVWVGGSPP
MAB_3778|M.abscessus_ATCC_1997      -----MGE----SKLNRYGVWKGG-PVTPEQARTIEDLGYGSVWVGGVFT
                                           .    . *.*:* :      . . *  ** *.* : *:*.   

TH_0027|M.thermoresistible__bu      AELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFHRIEKAYPGRFVL
MSMEG_1513|M.smegmatis_MC2_155      ADLSSVEPILENTETLQVATGIVNIWASDANTVAESFHRIEKAHPGRFVL
MMAR_1083|M.marinum_M               ADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAASYQRIESAHPGRFLL
MUL_0841|M.ulcerans_Agy99           ADLAWVEPASEQTTSLQLATGIVNICSAPADEVAASYQRIESAHPGRFLL
Mflv_5006|M.gilvum_PYR-GCK          ADLAFVEPILEKTETLQVATGIVNIWTADADEVAESYHRIEKAFPGRFLL
Mvan_1367|M.vanbaalenii_PYR-1       ADLAFVEPILEKTRSLQVATGIVNIWTADAAEVSESYHRIEKAFPGRFLL
Mb3492|M.bovis_AF2122/97            AALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRIEAAYPGRFLL
Rv3463|M.tuberculosis_H37Rv         AALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRIEAAYPGRFLL
MAV_4404|M.avium_104                AELAWVEPLLEATTTLQVATGIVNIWTAPAGPVAESFHRIEAAYPGRFLL
MAB_3778|M.abscessus_ATCC_1997      ADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAAFHRIEAAYPGRFLL
                                    * *  ***    * .* :*:***** :: .  :: :::*** *.****:*

TH_0027|M.thermoresistible__bu      GLGVGHPEATEEYAKPYEAMVTYLDVLDEATVPTSRRVLAALGPRMLQLA
MSMEG_1513|M.smegmatis_MC2_155      GVGVGHPEHTGEYRKPYDALVEYLDVLDAAKVPTSRRVLAALGDKVLKLS
MMAR_1083|M.marinum_M               GVGVGHPEHTQEYQKPYDALVAYLDDLDKAMVPDSRRVLAALGPRMLRLA
MUL_0841|M.ulcerans_Agy99           GVGVGHPEHTQEYQKPYDALVAYLDDLDKAMVPDSRRVLAALGPRMLRLA
Mflv_5006|M.gilvum_PYR-GCK          GVGVGHPEHTQEYTKPYQALVDYLDKLDAAKVPTSRMVVAALGPKVLKLA
Mvan_1367|M.vanbaalenii_PYR-1       GIGVGHPEHTQEYVKPYQALVDYLDKLDAAKVPTSRRVVAALGPKVLQLA
Mb3492|M.bovis_AF2122/97            GIGVGHAEMISEYRKPYNALVEYLDRLDDYGVPANRRVVAALGPRVLGLS
Rv3463|M.tuberculosis_H37Rv         GIGVGHAEMISEYRKPYNALVEYLDRLDDYGVPANRRVVAALGPRVLGLS
MAV_4404|M.avium_104                GIGVGHPEAHTEYRKPYDALADYLTRLDQYGVPAGRRVVAALGPRVLRLS
MAB_3778|M.abscessus_ATCC_1997      GVGAGHPEASAEYRKPYDALVEYLDGLDAAGVPKERRVLAALGPKVLKLS
                                    *:*.**.*   ** ***:*:. **  **   **  * *:**** ::* *:

TH_0027|M.thermoresistible__bu      AQRSAGAHPYLTTPQHTGQARNRIGPSVFLAPEHKVVLDTDAAAAREIGR
MSMEG_1513|M.smegmatis_MC2_155      AARSAGAHPYLTTPEHTEHARAVLGEAVFLAPEHKVVLNTDAAAARALGR
MMAR_1083|M.marinum_M               AQRSAGAHPYLTTPEHTGTARQLVGNTVFLAPEHKVVLTTDAAQARAVGR
MUL_0841|M.ulcerans_Agy99           AQRSAGAHPYLTTPEHTGTARQLVGNTVFLAPEHKVVLTTDAAQASAVDR
Mflv_5006|M.gilvum_PYR-GCK          AQRSAGAHPYLTTPVHTGQARELLGPTVLIAPEHKVVLTDDAEKAREIGR
Mvan_1367|M.vanbaalenii_PYR-1       AQRSAGAHPYLTTPVHTGQARELLGPTVLIAPEHKVVLTNDADKAREIGR
Mb3492|M.bovis_AF2122/97            ARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDSARARTVGR
Rv3463|M.tuberculosis_H37Rv         ARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDSARARTVGR
MAV_4404|M.avium_104                AERSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVVLTTDAEHARAVGR
MAB_3778|M.abscessus_ATCC_1997      ADRTAGAHPYLTTPEHTRQAREIIGPDALLVPEHKVVLSTDAPSAREIGR
                                    * *:********** **  **  :*  .::.*******  *:  *  :.*

TH_0027|M.thermoresistible__bu      QTIGFYLRLRNYVNNWKQLGFTDDDIAEPGSDELIDAMVAHGTAEQVADA
MSMEG_1513|M.smegmatis_MC2_155      KTVEFYLDLSNYVNNWRKLGFTDSDVEKPGSDKLIDAVVAHGTAGDIAAR
MMAR_1083|M.marinum_M               KFIDFYLGLSNYVNNWLKLGFTEDDVRKPGSDRLIDALVAYGTPDQIARR
MUL_0841|M.ulcerans_Agy99           KFIDFYLGLSNYVNNWLKLGFTEDDVRKPGSDRLIDALVAYGTPDQIARR
Mflv_5006|M.gilvum_PYR-GCK          GTVDFYLGLSNYVNNWKRLGFTEEDLERPGSDRFIDAVVAYGSPDEIAAR
Mvan_1367|M.vanbaalenii_PYR-1       GTVDFYLGLSNYLNNWKRLGFTDEDLTRPGSDRFIDAVVAHGSPDEIAAR
Mb3492|M.bovis_AF2122/97            QALDMYFNLANYRNNWKRLGFTDDEVSRPGSDRLVDAVVAYGTPDAIAAR
Rv3463|M.tuberculosis_H37Rv         QALDMYFNLANYRNNWKRLGFTDDEVSRPGSDRLVDAVVAYGTPDAIAAR
MAV_4404|M.avium_104                KALDIYFNLANYRNNWKRLGFTDDEITRPGSDRLVDALVAYGSVDRIAAR
MAB_3778|M.abscessus_ATCC_1997      RTVDFYLTLSNYVNNWKRLGFNDEDLTSPGSDAFIDAVVAHGTAAEIATR
                                      : :*: * ** *** :***.:.::  **** ::**:**:*:   :*  

TH_0027|M.thermoresistible__bu      LREHLDRGADHVAIQVLGGRERLLPTLXXSPRCGPNWGRCTSWSRARVWW
MSMEG_1513|M.smegmatis_MC2_155      LRQHIAAGADHVSIQVLGEPEDLIPTLT--ELAGP---------------
MMAR_1083|M.marinum_M               LGEHLEAGADHVAIQVLRPSREDKPMAALTELSGA---------------
MUL_0841|M.ulcerans_Agy99           LGEHHEAGADHVAIQVLRPSREDKSMAALTELSGA---------------
Mflv_5006|M.gilvum_PYR-GCK          LSEHLAAGADHVAIQVLGGGDELLSTLE--ELAGP---------------
Mvan_1367|M.vanbaalenii_PYR-1       LTEHLAAGADHVAIQVLGGSDELLSTLE--ELAGP---------------
Mb3492|M.bovis_AF2122/97            LNEHLLAGADHVPIQVLTEDDNLVSALT--ELAKP---------------
Rv3463|M.tuberculosis_H37Rv         LNEHLLAGADHVPIQVLTEDDNLVSALT--ELAKP---------------
MAV_4404|M.avium_104                LREHLDAGADHVPVQVLTKDENLVSALA--ELAGP---------------
MAB_3778|M.abscessus_ATCC_1997      LNEHLDAGADQVLIQVLG-DKGLVDTLT--SLADA---------------
                                    * :*   ***:* :***               . .               

TH_0027|M.thermoresistible__bu      TSPRSPRSAGRPGSGSSM
MSMEG_1513|M.smegmatis_MC2_155      LELKN-------------
MMAR_1083|M.marinum_M               LGLTR-------------
MUL_0841|M.ulcerans_Agy99           LGLTR-------------
Mflv_5006|M.gilvum_PYR-GCK          LDLKAAD-----------
Mvan_1367|M.vanbaalenii_PYR-1       LGLTA-------------
Mb3492|M.bovis_AF2122/97            LRLT--------------
Rv3463|M.tuberculosis_H37Rv         LRLT--------------
MAV_4404|M.avium_104                LGLKPS------------
MAB_3778|M.abscessus_ATCC_1997      LR----------------