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LRAGVFMLGTGFYFDWPNYRTMRRLLRRDPPAAARWQRFFGFAVAVPAIAAIHAVCFALDPILFGSLRRT QVVAPVFCIGHARSGTTYLHRLMANDPQFSYAMMYELFFPSLLEKRLLRLLFRVDAAVFGKRLRHRLDEI EKRRFAPTDDMHKTGFFVPEEDDAFLTWSLCSGFWILMFPFMGELDFYHVDRWPQRKRRRAMAFYKGCVR RQIAVNGGGTHLSKNPTFCGRVEALIETFPDARFIVPLRNPDETIPSLLKLLQTEWGLRGRDQRLVEKSL RVLAEQSLDSYQHPLDVLARHREVRSVLVDYRELIAQPEVTMRRIYRQLELDMGPAAAEAFAAAASGSGH ESTHRYSLEEFGLDSREIHTRLADLFDEYHWDTEAAARTEGTDAHVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0658 | - | - | 100% (397) | hypothetical protein MUL_0658 |
| M. ulcerans Agy99 | MUL_4091 | - | 6e-12 | 26.89% (305) | hypothetical protein MUL_4091 |
| M. ulcerans Agy99 | MUL_4363 | - | 1e-05 | 22.05% (331) | hypothetical protein MUL_4363 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2290c | - | 4e-14 | 26.07% (326) | hypothetical protein Mb2290c |
| M. gilvum PYR-GCK | Mflv_4074 | - | 2e-13 | 25.16% (314) | hypothetical protein Mflv_4074 |
| M. tuberculosis H37Rv | Rv2267c | - | 4e-14 | 26.07% (326) | hypothetical protein Rv2267c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 2e-09 | 23.26% (331) | putative sulfotransferase |
| M. marinum M | MMAR_0905 | - | 0.0 | 98.72% (391) | hypothetical protein MMAR_0905 |
| M. avium 104 | MAV_5269 | - | 5e-12 | 25.85% (325) | hypothetical protein MAV_5269 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 2e-10 | 23.90% (318) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2268 | - | 6e-10 | 24.04% (312) | hypothetical protein Mvan_2268 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0658|M.ulcerans_Agy99 --------------------------------------MRAGVFMLGTGF
MMAR_0905|M.marinum_M --------------------------------------------MLGTGF
Mflv_4074|M.gilvum_PYR-GCK ----------------------------MNRFAPEQLIVRACEATGLDDF
Mvan_2268|M.vanbaalenii_PYR-1 --------------------------MTAGRFDPDRLVEQACAAAGLDDF
MAV_5269|M.avium_104 -------------------------MSLQDRFAPERLIAAACEEAGSDDF
MAB_3968|M.abscessus_ATCC_1997 MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQWLRSAARRATG-LEW
MSMEG_5930|M.smegmatis_MC2_155 ------------------------------MGTVEDLHASATKATGLDDF
Mb2290c|M.bovis_AF2122/97 -------------------------------MKALRSSSRLSRWREWAAP
Rv2267c|M.tuberculosis_H37Rv -------------------------------MKALRSSSRLSRWREWAAP
MUL_0658|M.ulcerans_Agy99 YFDWPNYRTMRRLLRRDPPAAARWQRFFGFAVAVPAIAAIHAVCFALDPI
MMAR_0905|M.marinum_M YFDWPNYRTMLRLLRRDPPAAARWRRFFGFAVAVPAIAAIHAVCFALDPI
Mflv_4074|M.gilvum_PYR-GCK GDDDT-WRDGLDLVCDGLTTDARLNEIGVEIAAADLHRALTSRLHIVGWR
Mvan_2268|M.vanbaalenii_PYR-1 GDDGS-WRDGLHRLCDGLVADARLNDLGVEIAAMDIHRALTSRLAIVDWR
MAV_5269|M.avium_104 GAEG--WRPGLHRLTDGLINDARLSDIGVEIAHLDIMRALKNRLNVIAWR
MAB_3968|M.abscessus_ATCC_1997 VADAY-LDDALEVLAASLRNDAKLSFLGRKMVQVRLVGMLSTRLRLRELI
MSMEG_5930|M.smegmatis_MC2_155 GTDDDNYREALGVLLESYQRDAHLTELGSKMSRFFLRNALVARLLSEASW
Mb2290c|M.bovis_AF2122/97 LWVGCNFSAWMRLLIRN--RFAVHHSRWHFAVLYTFLSMVNSCLGLWQKI
Rv2267c|M.tuberculosis_H37Rv LWVGCNFSAWMRLLIRN--RFAVHHSRWHFAVLYTFLSMVNSCLGLWQKI
: . * :
MUL_0658|M.ulcerans_Agy99 LFG-SLRRTQVVAP-VFCIGHARSGTTYLHRLMANDPQFSYAMMYELFFP
MMAR_0905|M.marinum_M LFG-SLRRTQVVAP-VFCIGHARSGTTYLHRLMTNDPQFSYAMMYELFFP
Mflv_4074|M.gilvum_PYR-GCK TQHPEIAAAPVARP-IFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNP
Mvan_2268|M.vanbaalenii_PYR-1 ARHPAIGAAPVPRP-IFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNP
MAV_5269|M.avium_104 KAHPEVAEQKISAP-IFIVGQPRTGTTILYDLLAQDPALRAPLTWEVDEP
MAB_3968|M.abscessus_ATCC_1997 RKNPGIAQLPVEPP-IVIVGLQRTGTTLLHRLLAADPSAGSMSSWEGASP
MSMEG_5930|M.smegmatis_MC2_155 KANPQYADVEIERP-IFVTGLPRTGTTVLHRLLTADPAHQGLEMWLAEFP
Mb2290c|M.bovis_AF2122/97 VFGRRVAETVIADPPIFIVGHWRTGTTLLHELLVVDDRHTGPTGYECLAP
Rv2267c|M.tuberculosis_H37Rv VFGRRVAETVIADPPIFIVGHWRTGTTLLHELLVVDDRHTGPTGYECLAP
: * :. * *:*** *. *:. * : *
MUL_0658|M.ulcerans_Agy99 SLLEKRLLRLLFRVDAAVFGKRLRHRLDEIEKRRFAPTDDMHKTGFFVPE
MMAR_0905|M.marinum_M SLLEKRLLRLLFRVDAAVFGKRLRHRLDEIEKRRFAPTDDMHKTGFFVPE
Mflv_4074|M.gilvum_PYR-GCK FPLPRLDT---YTSDPRIAQTQASIEMSEQIVPGLLG---HHPMGALVGQ
Mvan_2268|M.vanbaalenii_PYR-1 FPPPEPET---YDTDPRIAQTQANIEMSEQIVPGLLA---HHPMGALVGQ
MAV_5269|M.avium_104 CPVPRPET---YHDDPRIARTQAGIDLSEQIMPGFLA---FHPMGALVGQ
MAB_3968|M.abscessus_ATCC_1997 LPHPEQPS---GAPDLRIAQAAKDERSLRYLAPQFFA---IHSVEAEAPE
MSMEG_5930|M.smegmatis_MC2_155 QPRPPRET---WPDNPVYQQLAASFSQHHQENPDYTG---LHFMTADEVE
Mb2290c|M.bovis_AF2122/97 ---------------HHFLLTEWFAPYVEFLVSKHRAMDNMDLSLHHPQE
Rv2267c|M.tuberculosis_H37Rv ---------------HHFLLTEWFAPYVEFLVSKHRAMDNMDLSLHHPQE
. . :
MUL_0658|M.ulcerans_Agy99 EDDAFLTWSLCSGFWILMFPFMGELDFYHVDRWPQRKRRRAMAFYK-GCV
MMAR_0905|M.marinum_M EDDAFLTWSLCSGFWILMFPFMGELDFYHVDRWPQRKRRRAMAFYK-GCV
Mflv_4074|M.gilvum_PYR-GCK ECVRIVAGQFCS----MIYPTQYRMPDYYRWLLYKADHGPAYRYHR-MFL
Mvan_2268|M.vanbaalenii_PYR-1 ECVRITAGQFTS----MIFPTQYRLPDYYRWLLYDADHGPAYRYHR-MFL
MAV_5269|M.avium_104 ECVRITAAEFVS----MIFSVQYRLPNYYRWLLYEADHAGAYRFHR-IFL
MAB_3968|M.abscessus_ATCC_1997 EDVLLLDFALHS----QMPEVMFHVPGYAKWLA-DQDMTPAYELHR-LLL
MSMEG_5930|M.smegmatis_MC2_155 ECWQLLRQSLHS----VSYETLAHLPTYANWLA-QQDWTRPYQRHR-RNL
Mb2290c|M.bovis_AF2122/97 DEFVWCMQGLPSP--YLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLF
Rv2267c|M.tuberculosis_H37Rv DEFVWCMQGLPSP--YLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLF
: : * . * . : .
MUL_0658|M.ulcerans_Agy99 RRQIAVNGGG--THLSKNPTFCGRVEALIETFPDARFIVPLRNPDETIPS
MMAR_0905|M.marinum_M RRQIAVNGGG--THLSKNPTFCGRVEALIETFPDARFIVPLRNPDETIPS
Mflv_4074|M.gilvum_PYR-GCK QHLQSGVGGPSCQWLLKSPAHLWQLEALLAEYPDALIVQTHRDPLNVIAS
Mvan_2268|M.vanbaalenii_PYR-1 QHLQSGVGG---RWLLKSPAHLWQLDALVAEYPDALIVQTHRDPLNVISS
MAV_5269|M.avium_104 QHLQSGVPG---QWLLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISS
MAB_3968|M.abscessus_ATCC_1997 QVLQWQQPRG--RWVLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTAS
MSMEG_5930|M.smegmatis_MC2_155 QLIGLNDAEK--RWVLKNPSHLFALDALFATYPDALVIQCHRPAETIMAS
Mb2290c|M.bovis_AF2122/97 RFVQQVYFRRRKTVILKNPTHSFRIKVLLEVFPQAKFIHIVRDPYVVYPS
Rv2267c|M.tuberculosis_H37Rv RFVQQVYFRRRKTVILKNPTHSFRIKVLLEVFPQAKFIHIVRDPYVVYPS
: : *.*:. :..*. :* * .: * . .*
MUL_0658|M.ulcerans_Agy99 LLKLLQTEWGLRGRDQRLVEKSLRVLAEQSLDS-YQHPLDVLARHREVRS
MMAR_0905|M.marinum_M LLKLLQTEWGLRGRDQRLVENSLRVLAEQSLDS-YQHPLDVLARHREVRS
Mflv_4074|M.gilvum_PYR-GCK ISALLHHLRRLASDDSSIPECAAQSREQIVAGLEYAVRLRDSGVPAANQI
Mvan_2268|M.vanbaalenii_PYR-1 ISALLHHLRRLASDESSIPDCAAQSREQIIVGLQRAMALRDSGALAAHQV
MAV_5269|M.avium_104 IAALTHHLRGMCSDESSITECAAQSYEEIVVGLDREMALRDRGAVPPGRV
MAB_3968|M.abscessus_ATCC_1997 SSSMLAHYQALFSDRVDHHELARYWLGKNAQIIDRAIAVR---AEHPAAF
MSMEG_5930|M.smegmatis_MC2_155 MCSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEAFTAER--AKHDPAQF
Mb2290c|M.bovis_AF2122/97 TIHLHKALYRIHGLQQPTFDGLDDKVVSTYVDLYRKLDEG-RELVDPTRF
Rv2267c|M.tuberculosis_H37Rv TIHLHKALYRIHGLQQPTFDGLDDKVVSTYVDLYRKLDEG-RELVDPTRF
: . :
MUL_0658|M.ulcerans_Agy99 VLVDYRELIAQPEVTMRRIYRQLELDMGPAAAEAFAAAASGSG---HEST
MMAR_0905|M.marinum_M VLVDYRELIAQPEVTMRRIYRQLEFDMGPAAAEAFAAAASGSG---HEST
Mflv_4074|M.gilvum_PYR-GCK VDVHFRDFMRDPFETIRALYARLGRELEPVAEQRMRDFLAAHP--GDHAG
Mvan_2268|M.vanbaalenii_PYR-1 VDVHFADFMRDPFETLRTLYRRLGRELDPVTEQRMRAHLAEHP--GDHGG
MAV_5269|M.avium_104 IDVRYADFMKDPWTTIKDIYERLDRELRPDAEQRMREFLASHP--SDGGR
MAB_3968|M.abscessus_ATCC_1997 VDINYTELLDDPIAAVQRIYHAADRRLSDDALTAMRVSLQQNRQ-HKHGE
MSMEG_5930|M.smegmatis_MC2_155 LDVDYDDFVADPLATVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPK
Mb2290c|M.bovis_AF2122/97 YELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLADHAD-YKTNS
Rv2267c|M.tuberculosis_H37Rv YELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLADHAD-YKTNS
: : ::: :* :. :* .
MUL_0658|M.ulcerans_Agy99 HRYSLEEFGLDSREIHTRLADLFDEYHWDTEAAARTEGTDAHVR
MMAR_0905|M.marinum_M HRYSLEEFGLDSREIHTRLADLFDEYHWDTEAAARTEGTDAHVR
Mflv_4074|M.gilvum_PYR-GCK NRYRWADTGLDAAEVRAQVRTYQERFGVPDEVLR----------
Mvan_2268|M.vanbaalenii_PYR-1 GRYRWADTGLDAAEVRDQVRAYQQRYDVPDEPLR----------
MAV_5269|M.avium_104 SRYTWSDTGLDAGAVRERVRAYQDRYGVPTEALR----------
MAB_3968|M.abscessus_ATCC_1997 HRYSLAQFGLTIAEVDAAYRRYIDHFAIQTERGGVRGDR-----
MSMEG_5930|M.smegmatis_MC2_155 HTYSLADYGLTSEAVKERFTGL----------------------
Mb2290c|M.bovis_AF2122/97 YQLTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG----
Rv2267c|M.tuberculosis_H37Rv YQLTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG----
: .: