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MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRWHFAVLYTFLSMVNSCLGLWQKIVFG RRVAETVIADPPIFIVGHWRTGTTLLHELLVVDDRHTGPTGYECLAPHHFLLTEWFAPYVEFLVSKHRAM DNMDLSLHHPQEDEFVWCMQGLPSPYLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRR RKTVILKNPTHSFRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKALYRIHGLQQPTFDGLDDKVVSTY VDLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLADHADYKTNSYQ LTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2290c | - | - | 100% (388) | hypothetical protein Mb2290c |
| M. bovis AF2122 / 97 | Mb3559c | - | 5e-13 | 24.25% (268) | hypothetical protein Mb3559c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3480 | - | 9e-13 | 25.73% (307) | hypothetical protein Mflv_3480 |
| M. tuberculosis H37Rv | Rv2267c | - | 0.0 | 100.00% (388) | hypothetical protein Rv2267c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4177c | - | 8e-15 | 27.24% (257) | hypothetical protein MAB_4177c |
| M. marinum M | MMAR_0905 | - | 2e-14 | 25.93% (324) | hypothetical protein MMAR_0905 |
| M. avium 104 | MAV_0631 | - | 2e-12 | 25.95% (262) | hypothetical protein MAV_0631 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 3e-11 | 25.39% (256) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 2e-12 | 25.67% (261) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4091 | - | 7e-15 | 26.98% (252) | hypothetical protein MUL_4091 |
| M. vanbaalenii PYR-1 | Mvan_5227 | - | 1e-12 | 26.12% (268) | hypothetical protein Mvan_5227 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0375|M.thermoresistible__bu -----MTPRTDVGTVEDLHASAVKACGLEDFGS-DDDNYKEALAVLLDSY
Mvan_5227|M.vanbaalenii_PYR-1 -----MTPRTDVGTVEDLHASAVKACGLDDFGS-DDDNYREALGVLLESY
MSMEG_5930|M.smegmatis_MC2_155 -----------MGTVEDLHASATKATGLDDFGT-DDDNYREALGVLLESY
MAV_0631|M.avium_104 -----MSDRTDIGTVEELHASATKLTGLDDFGT-DDDNYLQALEVLLDSY
MUL_4091|M.ulcerans_Agy99 -----MADRTDVGTVDELHASATKLVGLDDFGS-DQDTYREALEVLLDSY
MAB_4177c|M.abscessus_ATCC_199 MSFESSAERTSVGTVDDLHESATRLIGLDDFGDGSVDNYREALGVLLDSY
Mb2290c|M.bovis_AF2122/97 -----MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRW
Rv2267c|M.tuberculosis_H37Rv -----MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRW
Mflv_3480|M.gilvum_PYR-GCK -----MGEFDDIATPDDVLRLAAQRTGLSDVDG---DSWREGLAIVLDEV
MMAR_0905|M.marinum_M --------MLGTGFYFDWPNYRTMLRLLRRDPP--------AAARWRRFF
. .
TH_0375|M.thermoresistible__bu QREADLTELGSKMSRFFLRNALVARLVSEAAWKQYPQHADVVIERPIFVT
Mvan_5227|M.vanbaalenii_PYR-1 RRDADLTELGSKMQRFFVRNALVARLVSEAAFKQYPEHADVAIERPIFVT
MSMEG_5930|M.smegmatis_MC2_155 QRDAHLTELGSKMSRFFLRNALVARLLSEASWKANPQYADVEIERPIFVT
MAV_0631|M.avium_104 RREAGLTVLGSKMNRFFLRGALVARLLSESAWKQYPQYADVAIQRPIFVT
MUL_4091|M.ulcerans_Agy99 RREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQYPQYAEVPIQRPIFVT
MAB_4177c|M.abscessus_ATCC_199 QGEAGLTPLGSKMSRVFLRGALGARLLSEAAFKAHPDYAQVAIDRPIFVT
Mb2290c|M.bovis_AF2122/97 HFAVLYTFLSMVNSCLGLWQKIVFGRR---------VAETVIADPPIFIV
Rv2267c|M.tuberculosis_H37Rv HFAVLYTFLSMVNSCLGLWQKIVFGRR---------VAETVIADPPIFIV
Mflv_3480|M.gilvum_PYR-GCK NNCPAFTETGRARIIDDATKALARRLQVHDYIQQHPEVLEVPVERPLVTL
MMAR_0905|M.marinum_M GFAVAVPAIAAIHAVCFALDPILFGSLR-----------RTQVVAPVFCI
. . : . *:.
TH_0375|M.thermoresistible__bu GLPRTGTTALHRLLAADPAHQGLELWLAEFP---QPRPPRETWPDNPIYR
Mvan_5227|M.vanbaalenii_PYR-1 GLPRTGTTAVHRLLAADPRHQGLELWLAEFP---QPRPPRETWSQNPVFQ
MSMEG_5930|M.smegmatis_MC2_155 GLPRTGTTVLHRLLTADPAHQGLEMWLAEFP---QPRPPRETWPDNPVYQ
MAV_0631|M.avium_104 GLVRTGTTALHRLLGADPAHQGLHMWLAEFP---QPRPPRETWESNPLYR
MUL_4091|M.ulcerans_Agy99 GLVRTGTTALHRLLGADPAHQGLHMWLAEFP---QPRPPRETWETNPFYR
MAB_4177c|M.abscessus_ATCC_199 GLPRTGTTALHRLLNADPMHQGLEMWLADFP---QPRPPRDTWDANPVYQ
Mb2290c|M.bovis_AF2122/97 GHWRTGTTLLHELLVVDDRHTGPTGYECLAP---HHFLLTEWFAP-----
Rv2267c|M.tuberculosis_H37Rv GHWRTGTTLLHELLVVDDRHTGPTGYECLAP---HHFLLTEWFAP-----
Mflv_3480|M.gilvum_PYR-GCK GMPRTGTTVISYLLAADPKRRSLLHWECLNP---VPPATTDTLRSDPRCV
MMAR_0905|M.marinum_M GHARSGTTYLHRLMTNDPQFSYAMMYELFFPSLLEKRLLRLLFRVDAAVF
* *:*** : *: * : *
TH_0375|M.thermoresistible__bu QLEAQ--FTKAHQE-----NPDYTGLHFMTAGEVEECWQLLRQSVHSVSY
Mvan_5227|M.vanbaalenii_PYR-1 ALDAQ--FTKAHEE-----NPDYTGLHFMTADEVEECWQLLRQSLHSVSY
MSMEG_5930|M.smegmatis_MC2_155 QLAAS--FSQHHQE-----NPDYTGLHFMTADEVEECWQLLRQSLHSVSY
MAV_0631|M.avium_104 QLDAQ--FTQHHRD-----NPGYTGLHFMAAYELEECWQLLRQSLHSVSY
MUL_4091|M.ulcerans_Agy99 QLDAQ--LTQHRKD-----NTGYTGLHFMAAYELEECWQLLRQSLHSVSY
MAB_4177c|M.abscessus_ATCC_199 QLEGQ--FSKHHVE-----NPEFMGLHYMSASEVEECWQLLRQSVHSVSY
Mb2290c|M.bovis_AF2122/97 YVEFL--VSKHRAM-----DNMDLSLHHPQEDEFVWCMQGLPSPYLTIAF
Rv2267c|M.tuberculosis_H37Rv YVEFL--VSKHRAM-----DNMDLSLHHPQEDEFVWCMQGLPSPYLTIAF
Mflv_3480|M.gilvum_PYR-GCK ALLGEQKLILDMVK-----AAKMPIPHWEDADGPTECMFIHNQDFKGLSW
MMAR_0905|M.marinum_M GKRLRHRLDEIEKRRFAPTDDMHKTGFFVPEEDDAFLTWSLCSGFWILMF
. . . : :
TH_0375|M.thermoresistible__bu ETLAHVPSYARWLARQDWTK----PYQRHRRNLQLIGLNDVEKRWVLKNP
Mvan_5227|M.vanbaalenii_PYR-1 ETLAHVPTYSQWLARQDWTK----SYQRHRRNLQLIGLNDREKRWVLKNP
MSMEG_5930|M.smegmatis_MC2_155 ETLAHLPTYANWLAQQDWTR----PYQRHRRNLQLIGLNDAEKRWVLKNP
MAV_0631|M.avium_104 ETLAHVPSYAQWLSEQDWTP----SYQRHRRNLQLIGLNDADKRWVLKNP
MUL_4091|M.ulcerans_Agy99 ETLAHLPSYAQWLAKQDWTP----SYQRHRKNLQLIGLNDAEKRWVLKNP
MAB_4177c|M.abscessus_ATCC_199 ECLAHVPSYARWLSGQDWTP----AYRRYKANLQLIGLNDIEKRWVLKNP
Mb2290c|M.bovis_AF2122/97 P--NRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRRRKTVILKNP
Rv2267c|M.tuberculosis_H37Rv P--NRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRRRKTVILKNP
Mflv_3480|M.gilvum_PYR-GCK DAFMATPRYAEWLLNDADMIS---AYEYQKRYLQVLQS-KAPGTWSLKMP
MMAR_0905|M.marinum_M PFMGELDFYHVDRWPQRKRRR---AMAFYKGCVRRQIAVNGGGTHLSKNP
* : . * *
TH_0375|M.thermoresistible__bu SHLFALDALFATYPDALVVQCHRPAETIMASMCSLSQH-TTAGWSNTFVG
Mvan_5227|M.vanbaalenii_PYR-1 SHLFALDALMATYPDALVVQCHRPAETIMASMCSLAQH-TTEGWSNTFVG
MSMEG_5930|M.smegmatis_MC2_155 SHLFALDALFATYPDALVIQCHRPAETIMASMCSLSAH-TTAGWSNTFVG
MAV_0631|M.avium_104 SHLFALDALMATYPDALVIQTHRPVETIMASMCSLAQH-TAEGWSTTFVG
MUL_4091|M.ulcerans_Agy99 SHLFALDALMASYPDALVIQTHRPVETIMASMCSLAQH-TSEGWSTNFVG
MAB_4177c|M.abscessus_ATCC_199 SHLFALDALMEVYPDALVIQTHRPAETIIASVCSLNEH-ATAGWSETFTG
Mb2290c|M.bovis_AF2122/97 THSFRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKA-LYRIHGLQQPT
Rv2267c|M.tuberculosis_H37Rv THSFRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKA-LYRIHGLQQPT
Mflv_3480|M.gilvum_PYR-GCK SHSVHIEALLTVFPDARLIWAHRDPYKATGSLGNLLTLPKSMVLNPEAMT
MMAR_0905|M.marinum_M TFCGRVEALIETFPDARFIVPLRNPDETIPSLLKLLQT-EWGLRGRDQRL
:. :..*: :*:* .: * * * .
TH_0375|M.thermoresistible__bu -AQIGADAMETWTRGLRLFNEARANYDPAQFHDVEYADFVKDPIGTVEGI
Mvan_5227|M.vanbaalenii_PYR-1 -DVIGADSMETWSRGLELFNAERAKHDPAQFYDLDYFALIKDPVGAVGDI
MSMEG_5930|M.smegmatis_MC2_155 -AQIGADAMDTWARGLEAFTAERAKHDPAQFLDVDYDDFVADPLATVESV
MAV_0631|M.avium_104 -AQIGADAMDTWSRGLERFNTARAKYNPAQFYDVDYKELIADPLGTVADI
MUL_4091|M.ulcerans_Agy99 -AQIGADAMETWSRGLQPFDSARTNYDPAQFYDVDYRDLIADPMGTVADI
MAB_4177c|M.abscessus_ATCC_199 -ATLGADQLDTWARGLESFKSARAKYDESQFCDVDYFDFISDPIGTVESI
Mb2290c|M.bovis_AF2122/97 FDGLDDKVVSTYVDLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRL
Rv2267c|M.tuberculosis_H37Rv FDGLDDKVVSTYVDLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRL
Mflv_3480|M.gilvum_PYR-GCK TTEWGANLKDQMRQHVERPLRTRERIGDDRFFDMYYHEMMRDPMDVMRRL
MMAR_0905|M.marinum_M VENSLRVLAEQSLDSYQHPLDVLARHREVRSVLVDYRELIAQPEVTMRRI
. . : : * :: :* : :
TH_0375|M.thermoresistible__bu YRHFGLEFTDAARDAMTRLHTESQRGPRAPRHSYSLADYGLTAESVRDAF
Mvan_5227|M.vanbaalenii_PYR-1 YRSFGIDFPHAARAAMTATHEESKKGPRAPKHTYSLSDYGLTDEQVKERF
MSMEG_5930|M.smegmatis_MC2_155 YRHFGMPYTDAARAAVTEVYEASRRGPRAPKHTYSLADYGLTSEAVKERF
MAV_0631|M.avium_104 YRHFGLTLTEEAKAAMAKTHADSQSGERAPKHSYSLADYGLSVETVKERF
MUL_4091|M.ulcerans_Agy99 YRHFGLTLTDEARAAMAKIHAESQTGERAPKHRYSLADYGLTAEAVKERF
MAB_4177c|M.abscessus_ATCC_199 YRHFGLELSASALVEMQKMNDESQKGPRAPKHVYSLADYGLSKEAVMERF
Mb2290c|M.bovis_AF2122/97 YQHLGLGDFECYLPRLRQYLAD-HADYKTNSYQLTVEQRAIVDEHWGEII
Rv2267c|M.tuberculosis_H37Rv YQHLGLGDFECYLPRLRQYLAD-HADYKTNSYQLTVEQRAIVDEHWGEII
Mflv_3480|M.gilvum_PYR-GCK YDWAGDPLTPDTETRMQSWLAEHPQGLLG-HSSYSLDQYGLSVEELTPVF
MMAR_0905|M.marinum_M YRQLEFDMGPAAAEAFAAAASG---SGHESTHRYSLEEFGLDSREIHTRL
* . . :: : .: . :
TH_0375|M.thermoresistible__bu SGL----------------------
Mvan_5227|M.vanbaalenii_PYR-1 KGL----------------------
MSMEG_5930|M.smegmatis_MC2_155 TGL----------------------
MAV_0631|M.avium_104 AGL----------------------
MUL_4091|M.ulcerans_Agy99 AGF----------------------
MAB_4177c|M.abscessus_ATCC_199 AGL----------------------
Mb2290c|M.bovis_AF2122/97 DRYGYDRHTPEPARLRPAVGG----
Rv2267c|M.tuberculosis_H37Rv DRYGYDRHTPEPARLRPAVGG----
Mflv_3480|M.gilvum_PYR-GCK AEYLGTFDIELEDA-----------
MMAR_0905|M.marinum_M ADLFDEYHWDTEAAARTEGTDAHVR