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QPQQGQSGQLTLDLAHRRNMVRDLTGGALLVLAVFFPWNLYFGFRIPGSSNYVLAVLLAVTLLSLIAIAV PYVGPWRLSGTRFAPTATNRLRLGLNIPYLLLLLAFVVYDIFQTIRSGGTVNVPGGVGPGGWLGIAGAML CAQPVSTGQPGDNENYDNWLFTARILGYASMFGAALSSGFNLAWRVRYALQPTNSASGFGRQNIAVIDTA LVYGVVALVAVLVASRWLLKGTREYQLPTIALGASAMVAGIIVWVLPVGREIDAFHGIAQNTSTAGVGYE GYLVWATGAAIFAPMALVRSHTHPIGRDIWRAAARNELLLIAVWCLGSVVMRLTDLSTAVMLNFPYSRYD TMTLAAFDLVTAALAFWLRINLVNQALPARLISSLCGFLLTLTVSRVIVGVVLAPRFAASPDARPNPVYG NNLAQQITSTFDVTLCGLALGIVVAVIISGRRSATQTKQPGRPRRRQRRTGQPGPARGGAAVPSEAETTQ FRSPAALDAHDDAPTTVLSGPGRAPRIFRSGESTGPLPPKIYRRLDDPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0636 | - | - | 100% (540) | hypothetical protein MUL_0636 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0551c | - | 1e-172 | 60.64% (531) | integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0537c | - | 1e-172 | 60.64% (531) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0883 | - | 0.0 | 99.26% (539) | hypothetical protein MMAR_0883 |
| M. avium 104 | MAV_4608 | - | 1e-154 | 57.28% (536) | hypothetical protein MAV_4608 |
| M. smegmatis MC2 155 | MSMEG_1189 | - | 1e-98 | 39.88% (519) | hypothetical protein MSMEG_1189 |
| M. thermoresistible (build 8) | TH_4600 | - | 2e-57 | 43.00% (307) | PUTATIVE putative hypothetical protein Mjls_0809 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0636|M.ulcerans_Agy99 ----------------MQPQQGQSGQLTLDL----------AHRRNMVRD
MMAR_0883|M.marinum_M -MSLGSDDTPTGPIAGAQPQQGQSGQLTLDL----------AHRRNMVRD
Mb0551c|M.bovis_AF2122/97 --------------------MG----LSSDD----------TRRREVVRD
Rv0537c|M.tuberculosis_H37Rv --------------------MG----LSSDD----------TRRREVVRD
MAV_4608|M.avium_104 MVSQSSDDTPTGPIAGQPRQPAAPRIIRSHATGATPPPGPATTGRRVAAD
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 -MTDPRYDASETVAVATTAAPSVARSPRVG---------YVPTRTNRVRD
MUL_0636|M.ulcerans_Agy99 LTGGALLVLAVFFPWNLYFGFRIPGSSNYVLAVLLAVTLLSLIAIAVPYV
MMAR_0883|M.marinum_M LTGGALLVLAVFFPWNLYFGFRIPGSSNYVLAVLLAVTLLSLIAIAVPYV
Mb0551c|M.bovis_AF2122/97 LAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFA
Rv0537c|M.tuberculosis_H37Rv LAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFA
MAV_4608|M.avium_104 LTAVALLLAAVLLPWNLYFGVGIPDSNPIVFAVLVAVTALALAALAV--A
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 GVAVVLLVLALLLPWNLQFGVGVPGSDGSTFVVLAVVTVLALAAALAPHV
MUL_0636|M.ulcerans_Agy99 GPWRLSGTRFAPTATNRLRLGLNIPYLLLLLAFVVYDIFQTIRSGGTVNV
MMAR_0883|M.marinum_M GPWRLSGTRFAPTATNRLRLGLNIPYLLLLLAFVVYDIFQTIRSGGTVNV
Mb0551c|M.bovis_AF2122/97 G--RRS----------QLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHV
Rv0537c|M.tuberculosis_H37Rv G--RRS----------QLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHV
MAV_4608|M.avium_104 GSWRAGGARFDPARAARLRLALNVPYLLLVLAFVGFDAVQTVRFGGTVDV
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 GPLRLAAPKADVRRTGVVRLLLCVAYLVVVIGFVAFHLVQTVRNGGTGAV
MUL_0636|M.ulcerans_Agy99 PGGVGPGGWLGIAGAMLCAQPVSTGQPGD-------NENYDNWLFTARIL
MMAR_0883|M.marinum_M PGGVGPGGWLGIAGAMLCAQPVSTGQPGD-------NENYDNWLFTARIL
Mb0551c|M.bovis_AF2122/97 PGGVGPGGWLGITGALLSAQPALTGATTD-------EGSHSRWLRATQFL
Rv0537c|M.tuberculosis_H37Rv PGGVGPGGWLGITGALLSAQPALTGATTD-------EGSHSRWLRATQFL
MAV_4608|M.avium_104 PGGVGPGAWVGIAGALLSAQAVPAGTAAAPVPGTPAGDEATGWHRAARII
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 PPGVGPGLLLGAAGALLAAQPPITSITIE-------DNKFRRWYTVTQAI
MUL_0636|M.ulcerans_Agy99 GYASMFGAALSSGFNLAWRVRYALQPTNSASGFGRQNIAVIDTALVYGVV
MMAR_0883|M.marinum_M GYASMFGAALSSGFNLAWRVRYALQPTNSASGFGRQNIAVIDTALVYGVV
Mb0551c|M.bovis_AF2122/97 GYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVV
Rv0537c|M.tuberculosis_H37Rv GYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVV
MAV_4608|M.avium_104 GALSMLAAVLSFGFNLYWRVRYALQSSGGAAQFGKENIAVIATAVVYGVV
TH_4600|M.thermoresistible__bu ------------------------------------------------VV
MSMEG_1189|M.smegmatis_MC2_155 GFLSIALATLSVAFNLYWRLRYLFVT---EVAFGSHDVAVIVTTVLYGAE
.
MUL_0636|M.ulcerans_Agy99 ALVAVLVASRWLLKGTREYQLPTIALGASAMVAGIIVWVLPVGREIDAFH
MMAR_0883|M.marinum_M ALVAVLVASRWLLKGTREYQLPTIALGASAMVAGIIVWVLPVGREIDAFH
Mb0551c|M.bovis_AF2122/97 ALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFH
Rv0537c|M.tuberculosis_H37Rv ALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFH
MAV_4608|M.avium_104 ALVAVLVASRWLLRSDRASRLTTIALGTSTLAAGILVWLLPAGRDLDAFH
TH_4600|M.thermoresistible__bu AVIPLVIGYRWLRSTRLAARVATLLLAVSALVAGMIVWVLPVGREVDAFH
MSMEG_1189|M.smegmatis_MC2_155 AMTALVIASRWLTEKTAAARLATTAVGVSGAVAATLVWLMGIGRDIDAFH
*: .:::. *** :.* :. * *. :** : **::****
MUL_0636|M.ulcerans_Agy99 GIAQNTSTAGVGYEGYLVWATGAAIFAPMALVRS-HTHPIGRDIWRAAAR
MMAR_0883|M.marinum_M GIAQNTSTAGVGYEGYLVWAAGAAIFAPMALVRS-HTHPIGRDIWRAAAR
Mb0551c|M.bovis_AF2122/97 GIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASR
Rv0537c|M.tuberculosis_H37Rv GIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASR
MAV_4608|M.avium_104 GIAQNTSTAGVGFEGYLAWAAGAALFAPRTLFERRTPSHTEESAWRATAR
TH_4600|M.thermoresistible__bu GIAQNTGISGVGYEGYLSWVAVAAIVA----VPTVSALRDDRAVWRRAVR
MSMEG_1189|M.smegmatis_MC2_155 GIAENTSTAAVGYEGYLAWAVGAAIVAPTTLYAVFLIKPPTLGAYRGAAL
***:**. :.**:**** *.. **: * :* :
MUL_0636|M.ulcerans_Agy99 NELLLIAVWCLGSVVMRLTDLSTAVMLNFPYSRYDTMTLAAFDLVTAALA
MMAR_0883|M.marinum_M NGLLLIAVWCLGSVVMRLTDLSTAVMLNFPYSRYDTMTLAAFDLVTAALA
Mb0551c|M.bovis_AF2122/97 NGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLA
Rv0537c|M.tuberculosis_H37Rv NGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLA
MAV_4608|M.avium_104 NGLLLIAVWALGSMAMRITDLAVAVTLNYPFSRYDSLVLAAFDLVTAVLA
TH_4600|M.thermoresistible__bu RCLLLIGAWCAGTAVLRLADVALSAVLDLPAPPYNGTALMAFDLLAAVLA
MSMEG_1189|M.smegmatis_MC2_155 KCLTLIAFWGFAAAALRIVDYAVAESLNLPRALYDSVAMTVFSLLTAIIA
. * **. * .: .:*:.* : *: * . *: .: .*.* :* :*
MUL_0636|M.ulcerans_Agy99 FWLRINLVNQALPARLISSLCGFLLTLTVSRVIVGVVLAPRFAASPDA-R
MMAR_0883|M.marinum_M FWLRINLVNQALPARLISSLCGFLLTLTVSRVIVGVVLAPRFAASPDA-R
Mb0551c|M.bovis_AF2122/97 IWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGG-S
Rv0537c|M.tuberculosis_H37Rv IWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGG-S
MAV_4608|M.avium_104 IWLRRQLAN--LAARLVTSLCGLVAALAVARVVVGVQLAPRFADTPNSPV
TH_4600|M.thermoresistible__bu WWLFLNAGR-FAPGRMLTTLFAVLFAAVVSRVIVGIALVPRSEPLDPA-T
MSMEG_1189|M.smegmatis_MC2_155 RWVHRQISKGVVSTVVTAAFSAVLFVFTVADVAIGVALAPRYAAPAPD--
*: : . : ::: ..: . .*: * :*: *.**
MUL_0636|M.ulcerans_Agy99 PNPVYGNNLAQQITSTFDVTLCGLALGIVVAVIISGRRSATQTKQPGRPR
MMAR_0883|M.marinum_M PNPVYGNNLAQQITSTFDVTLCGLALGIVVAVIISGRRSATQTKRPGRPR
Mb0551c|M.bovis_AF2122/97 AHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIG--------------
Rv0537c|M.tuberculosis_H37Rv AHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIG--------------
MAV_4608|M.avium_104 HHPVYGNNLAQQITSVFDVTLCGLALGILVAAVVAGQLGRRRRAR----R
TH_4600|M.thermoresistible__bu INAVFGNTLVQQITSTFDVTLVVLALALSVIAIMTAR-------------
MSMEG_1189|M.smegmatis_MC2_155 --AIYGNNLAQQITSTFDIVVCVLSLLVLAVLLFTGPLAG---------Y
.::** *.*****.**:.: *:* : . :. .
MUL_0636|M.ulcerans_Agy99 RRQRRTGQPGPARGGAAVPSEA------ETTQFRSPAALDAHDDAPTTVL
MMAR_0883|M.marinum_M RRQRRTGQPGPARGGAAVPSEA------ETTQFRSPAALDAHDDAPTTVL
Mb0551c|M.bovis_AF2122/97 -RLRQLPQP-----------------------------------PHTPAL
Rv0537c|M.tuberculosis_H37Rv -RLRQLPQP-----------------------------------PHTPAL
MAV_4608|M.avium_104 AARRRAAQANAAAPTTRIPVSQGAAPSAAATTRIATGGPGADHEPPTTEI
TH_4600|M.thermoresistible__bu PARPTASKPAGPAG------------------------------PAERRA
MSMEG_1189|M.smegmatis_MC2_155 LSRRQTAKPAPAPAAQVTPAPVTP-----------AVPVDDSAPPTLARR
:. .
MUL_0636|M.ulcerans_Agy99 SGPGRAPRIFR---SGESTGPLP--------------------PKIYRRL
MMAR_0883|M.marinum_M SGPGRAPRIFR---SGESTGPLP--------------------PKIYRRP
Mb0551c|M.bovis_AF2122/97 SRPAGSPRIFR---SAGSTHPVR--------------------PKIYRPP
Rv0537c|M.tuberculosis_H37Rv SRPAGSPRIFR---SAGSTHPVR--------------------PKIYRPP
MAV_4608|M.avium_104 PPLAGSPRIFRGDDSGTRQIPVPK-------------------PQIYRPP
TH_4600|M.thermoresistible__bu AAPRKSASAWPTIVIPTRSGPAR----------------------IVRPG
MSMEG_1189|M.smegmatis_MC2_155 PQPAAVPKIVRLKEDSTTVLPAPPTTELQVPTTTLRIQRRPSSGFTPRPP
. . * *
MUL_0636|M.ulcerans_Agy99 DDPS
MMAR_0883|M.marinum_M DDPS
Mb0551c|M.bovis_AF2122/97 DHSS
Rv0537c|M.tuberculosis_H37Rv DHSS
MAV_4608|M.avium_104 QQ--
TH_4600|M.thermoresistible__bu HDDD
MSMEG_1189|M.smegmatis_MC2_155 DNNR
..