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MVSQSSDDTPTGPIAGQPRQPAAPRIIRSHATGATPPPGPATTGRRVAADLTAVALLLAAVLLPWNLYFG VGIPDSNPIVFAVLVAVTALALAALAVAGSWRAGGARFDPARAARLRLALNVPYLLLVLAFVGFDAVQTV RFGGTVDVPGGVGPGAWVGIAGALLSAQAVPAGTAAAPVPGTPAGDEATGWHRAARIIGALSMLAAVLSF GFNLYWRVRYALQSSGGAAQFGKENIAVIATAVVYGVVALVAVLVASRWLLRSDRASRLTTIALGTSTLA AGILVWLLPAGRDLDAFHGIAQNTSTAGVGFEGYLAWAAGAALFAPRTLFERRTPSHTEESAWRATARNG LLLIAVWALGSMAMRITDLAVAVTLNYPFSRYDSLVLAAFDLVTAVLAIWLRRQLANLAARLVTSLCGLV AALAVARVVVGVQLAPRFADTPNSPVHHPVYGNNLAQQITSVFDVTLCGLALGILVAAVVAGQLGRRRRA RRAARRRAAQANAAAPTTRIPVSQGAAPSAAATTRIATGGPGADHEPPTTEIPPLAGSPRIFRGDDSGTR QIPVPKPQIYRPPQQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4608 | - | - | 100% (575) | hypothetical protein MAV_4608 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0551c | - | 1e-149 | 56.18% (534) | integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0537c | - | 1e-149 | 56.18% (534) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0883 | - | 1e-162 | 56.36% (582) | hypothetical protein MMAR_0883 |
| M. smegmatis MC2 155 | MSMEG_1189 | - | 1e-105 | 42.68% (553) | hypothetical protein MSMEG_1189 |
| M. thermoresistible (build 8) | TH_4600 | - | 2e-52 | 41.43% (280) | PUTATIVE putative hypothetical protein Mjls_0809 |
| M. ulcerans Agy99 | MUL_0636 | - | 1e-154 | 57.28% (536) | hypothetical protein MUL_0636 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0551c|M.bovis_AF2122/97 --------------------MG----LSSDD----------TRRREVVRD
Rv0537c|M.tuberculosis_H37Rv --------------------MG----LSSDD----------TRRREVVRD
MMAR_0883|M.marinum_M -MSLGSDDTPTGPIAGAQPQQGQSGQLTLDL----------AHRRNMVRD
MUL_0636|M.ulcerans_Agy99 ----------------MQPQQGQSGQLTLDL----------AHRRNMVRD
MAV_4608|M.avium_104 MVSQSSDDTPTGPIAGQPRQPAAPRIIRSHATGATPPPGPATTGRRVAAD
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 -MTDPRYDASETVAVATTAAPSVARSPRVG---------YVPTRTNRVRD
Mb0551c|M.bovis_AF2122/97 LAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFA
Rv0537c|M.tuberculosis_H37Rv LAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFA
MMAR_0883|M.marinum_M LTGGALLVLAVFFPWNLYFGFRIPGSSNYVLAVLLAVTLLSLIAIAVPYV
MUL_0636|M.ulcerans_Agy99 LTGGALLVLAVFFPWNLYFGFRIPGSSNYVLAVLLAVTLLSLIAIAVPYV
MAV_4608|M.avium_104 LTAVALLLAAVLLPWNLYFGVGIPDSNPIVFAVLVAVTALALAALAV--A
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 GVAVVLLVLALLLPWNLQFGVGVPGSDGSTFVVLAVVTVLALAAALAPHV
Mb0551c|M.bovis_AF2122/97 G--RRS----------QLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHV
Rv0537c|M.tuberculosis_H37Rv G--RRS----------QLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHV
MMAR_0883|M.marinum_M GPWRLSGTRFAPTATNRLRLGLNIPYLLLLLAFVVYDIFQTIRSGGTVNV
MUL_0636|M.ulcerans_Agy99 GPWRLSGTRFAPTATNRLRLGLNIPYLLLLLAFVVYDIFQTIRSGGTVNV
MAV_4608|M.avium_104 GSWRAGGARFDPARAARLRLALNVPYLLLVLAFVGFDAVQTVRFGGTVDV
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 GPLRLAAPKADVRRTGVVRLLLCVAYLVVVIGFVAFHLVQTVRNGGTGAV
Mb0551c|M.bovis_AF2122/97 PGGVGPGGWLGITGALLSAQPALTGATTD-------EGSHSRWLRATQFL
Rv0537c|M.tuberculosis_H37Rv PGGVGPGGWLGITGALLSAQPALTGATTD-------EGSHSRWLRATQFL
MMAR_0883|M.marinum_M PGGVGPGGWLGIAGAMLCAQPVSTGQPGD-------NENYDNWLFTARIL
MUL_0636|M.ulcerans_Agy99 PGGVGPGGWLGIAGAMLCAQPVSTGQPGD-------NENYDNWLFTARIL
MAV_4608|M.avium_104 PGGVGPGAWVGIAGALLSAQAVPAGTAAAPVPGTPAGDEATGWHRAARII
TH_4600|M.thermoresistible__bu --------------------------------------------------
MSMEG_1189|M.smegmatis_MC2_155 PPGVGPGLLLGAAGALLAAQPPITSITIE-------DNKFRRWYTVTQAI
Mb0551c|M.bovis_AF2122/97 GYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVV
Rv0537c|M.tuberculosis_H37Rv GYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVV
MMAR_0883|M.marinum_M GYASMFGAALSSGFNLAWRVRYALQPTNSASGFGRQNIAVIDTALVYGVV
MUL_0636|M.ulcerans_Agy99 GYASMFGAALSSGFNLAWRVRYALQPTNSASGFGRQNIAVIDTALVYGVV
MAV_4608|M.avium_104 GALSMLAAVLSFGFNLYWRVRYALQSSGGAAQFGKENIAVIATAVVYGVV
TH_4600|M.thermoresistible__bu ------------------------------------------------VV
MSMEG_1189|M.smegmatis_MC2_155 GFLSIALATLSVAFNLYWRLRYLFVT---EVAFGSHDVAVIVTTVLYGAE
.
Mb0551c|M.bovis_AF2122/97 ALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFH
Rv0537c|M.tuberculosis_H37Rv ALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFH
MMAR_0883|M.marinum_M ALVAVLVASRWLLKGTREYQLPTIALGASAMVAGIIVWVLPVGREIDAFH
MUL_0636|M.ulcerans_Agy99 ALVAVLVASRWLLKGTREYQLPTIALGASAMVAGIIVWVLPVGREIDAFH
MAV_4608|M.avium_104 ALVAVLVASRWLLRSDRASRLTTIALGTSTLAAGILVWLLPAGRDLDAFH
TH_4600|M.thermoresistible__bu AVIPLVIGYRWLRSTRLAARVATLLLAVSALVAGMIVWVLPVGREVDAFH
MSMEG_1189|M.smegmatis_MC2_155 AMTALVIASRWLTEKTAAARLATTAVGVSGAVAATLVWLMGIGRDIDAFH
*: .:::. *** :.* :. * *. :** : **::****
Mb0551c|M.bovis_AF2122/97 GIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASR
Rv0537c|M.tuberculosis_H37Rv GIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASR
MMAR_0883|M.marinum_M GIAQNTSTAGVGYEGYLVWAAGAAIFAPMALVRS-HTHPIGRDIWRAAAR
MUL_0636|M.ulcerans_Agy99 GIAQNTSTAGVGYEGYLVWATGAAIFAPMALVRS-HTHPIGRDIWRAAAR
MAV_4608|M.avium_104 GIAQNTSTAGVGFEGYLAWAAGAALFAPRTLFERRTPSHTEESAWRATAR
TH_4600|M.thermoresistible__bu GIAQNTGISGVGYEGYLSWVAVAAIVA----VPTVSALRDDRAVWRRAVR
MSMEG_1189|M.smegmatis_MC2_155 GIAENTSTAAVGYEGYLAWAVGAAIVAPTTLYAVFLIKPPTLGAYRGAAL
***:**. :.**:**** *.. **: * :* :
Mb0551c|M.bovis_AF2122/97 NGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLA
Rv0537c|M.tuberculosis_H37Rv NGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLA
MMAR_0883|M.marinum_M NGLLLIAVWCLGSVVMRLTDLSTAVMLNFPYSRYDTMTLAAFDLVTAALA
MUL_0636|M.ulcerans_Agy99 NELLLIAVWCLGSVVMRLTDLSTAVMLNFPYSRYDTMTLAAFDLVTAALA
MAV_4608|M.avium_104 NGLLLIAVWALGSMAMRITDLAVAVTLNYPFSRYDSLVLAAFDLVTAVLA
TH_4600|M.thermoresistible__bu RCLLLIGAWCAGTAVLRLADVALSAVLDLPAPPYNGTALMAFDLLAAVLA
MSMEG_1189|M.smegmatis_MC2_155 KCLTLIAFWGFAAAALRIVDYAVAESLNLPRALYDSVAMTVFSLLTAIIA
. * **. * .: .:*:.* : *: * . *: .: .*.* :* :*
Mb0551c|M.bovis_AF2122/97 IWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGG-S
Rv0537c|M.tuberculosis_H37Rv IWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGG-S
MMAR_0883|M.marinum_M FWLRINLVNQALPARLISSLCGFLLTLTVSRVIVGVVLAPRFAASPDA-R
MUL_0636|M.ulcerans_Agy99 FWLRINLVNQALPARLISSLCGFLLTLTVSRVIVGVVLAPRFAASPDA-R
MAV_4608|M.avium_104 IWLRRQLAN--LAARLVTSLCGLVAALAVARVVVGVQLAPRFADTPNSPV
TH_4600|M.thermoresistible__bu WWLFLNAGR-FAPGRMLTTLFAVLFAAVVSRVIVGIALVPRSEPLDPA-T
MSMEG_1189|M.smegmatis_MC2_155 RWVHRQISKGVVSTVVTAAFSAVLFVFTVADVAIGVALAPRYAAPAPD--
*: : . : ::: ..: . .*: * :*: *.**
Mb0551c|M.bovis_AF2122/97 AHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIG--------------
Rv0537c|M.tuberculosis_H37Rv AHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIG--------------
MMAR_0883|M.marinum_M PNPVYGNNLAQQITSTFDVTLCGLALGIVVAVIISGRRSATQTKRPGRPR
MUL_0636|M.ulcerans_Agy99 PNPVYGNNLAQQITSTFDVTLCGLALGIVVAVIISGRRSATQTKQPGRPR
MAV_4608|M.avium_104 HHPVYGNNLAQQITSVFDVTLCGLALGILVAAVVAGQLGRRRRAR----R
TH_4600|M.thermoresistible__bu INAVFGNTLVQQITSTFDVTLVVLALALSVIAIMTAR-------------
MSMEG_1189|M.smegmatis_MC2_155 --AIYGNNLAQQITSTFDIVVCVLSLLVLAVLLFTGPLAG---------Y
.::** *.*****.**:.: *:* : . :. .
Mb0551c|M.bovis_AF2122/97 -RLRQLPQP-----------------------------------PHTPAL
Rv0537c|M.tuberculosis_H37Rv -RLRQLPQP-----------------------------------PHTPAL
MMAR_0883|M.marinum_M RRQRRTGQPGPARGGAAVPSEA------ETTQFRSPAALDAHDDAPTTVL
MUL_0636|M.ulcerans_Agy99 RRQRRTGQPGPARGGAAVPSEA------ETTQFRSPAALDAHDDAPTTVL
MAV_4608|M.avium_104 AARRRAAQANAAAPTTRIPVSQGAAPSAAATTRIATGGPGADHEPPTTEI
TH_4600|M.thermoresistible__bu PARPTASKPAGPAG------------------------------PAERRA
MSMEG_1189|M.smegmatis_MC2_155 LSRRQTAKPAPAPAAQVTPAPVTP-----------AVPVDDSAPPTLARR
:. .
Mb0551c|M.bovis_AF2122/97 SRPAGSPRIFR---SAGSTHPVR--------------------PKIYRPP
Rv0537c|M.tuberculosis_H37Rv SRPAGSPRIFR---SAGSTHPVR--------------------PKIYRPP
MMAR_0883|M.marinum_M SGPGRAPRIFR---SGESTGPLP--------------------PKIYRRP
MUL_0636|M.ulcerans_Agy99 SGPGRAPRIFR---SGESTGPLP--------------------PKIYRRL
MAV_4608|M.avium_104 PPLAGSPRIFRGDDSGTRQIPVPK-------------------PQIYRPP
TH_4600|M.thermoresistible__bu AAPRKSASAWPTIVIPTRSGPAR----------------------IVRPG
MSMEG_1189|M.smegmatis_MC2_155 PQPAAVPKIVRLKEDSTTVLPAPPTTELQVPTTTLRIQRRPSSGFTPRPP
. . * *
Mb0551c|M.bovis_AF2122/97 DHSS
Rv0537c|M.tuberculosis_H37Rv DHSS
MMAR_0883|M.marinum_M DDPS
MUL_0636|M.ulcerans_Agy99 DDPS
MAV_4608|M.avium_104 QQ--
TH_4600|M.thermoresistible__bu HDDD
MSMEG_1189|M.smegmatis_MC2_155 DNNR
..