For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTHAFSAAGGISGQPINRVDGPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQPGVL AVLTDFTGVRLPFGTGQVFFFGQPIAVVVATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIA DYVRGTPDQVMIRAAGISDLNFSIARNNHNAVELPATIAKWDGDRLTLWDKVQHINGARRSYARAFGMSE ERVRLISPFVGGAFGSAGRMWPHQLLTVFAARRMQLPVKLVLTRKQMYSSVGFRPTSRQRMAIGADPSGR LMAMIHEGRTETAQYGIYEDGIVRSPQLTYQVPNMSSTYRVVPLDINLPWFMRGPGAVTGTFALESTMDD LAHRLGIDPIELRLRNEPRIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSIPGANRDGDSFVGIGMATA AYFTYRSKCAAIARISADGTAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDSRFPPAPAHSA SRTTASVGSAVFTVANMLHDKFIRAAVTDPQSPLAGLRPEDVMVTNGHMFSTVATDGPARGESYQDLLRR RGWPALESEHTWTPDDAGKRYSTYAYGAVFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGM IGGIGMALLEGTELDYRDGRVVNANISDYLVPINADVPVLDASFLPAQDTIADPIGVKGLGELVIIAVPA AIANAVFNATGKRVTDLPIRVEQLL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_4580 | coxL_1 | - | 100% (725) | carbon monoxyde dehydrogenase (large chain), CoxL_1 |
M. ulcerans Agy99 | MUL_0115 | coxL | 5e-50 | 26.54% (765) | carbon monoxyde dehydrogenase (large chain), CoxL |
M. ulcerans Agy99 | MUL_0588 | coxL_2 | 1e-45 | 26.19% (775) | aerobic-type carbon monoxide dehydrogenase, CoxL_2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0380c | - | 5e-49 | 26.34% (767) | carbon monoxyde dehydrogenase large subunit |
M. gilvum PYR-GCK | Mflv_0284 | - | 1e-101 | 33.65% (740) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
M. tuberculosis H37Rv | Rv0373c | - | 4e-49 | 26.34% (767) | carbon monoxyde dehydrogenase large subunit |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2925c | - | 3e-44 | 27.50% (789) | xanthine dehydrogenase family protein |
M. marinum M | MMAR_0836 | coxL_1 | 0.0 | 99.03% (725) | carbon monoxyde dehydrogenase (large chain), CoxL_1 |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_0870 | - | 0.0 | 57.58% (719) | oxidoreductase |
M. thermoresistible (build 8) | TH_0176 | - | 6e-56 | 27.19% (765) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN) |
M. vanbaalenii PYR-1 | Mvan_2075 | - | 1e-118 | 36.70% (752) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
CLUSTAL 2.0.9 multiple sequence alignment MUL_4580|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0836|M.marinum_M -------------------------------------------------- MSMEG_0870|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0284|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2075|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0176|M.thermoresistible__bu -------------------------------------------------- MAB_2925c|M.abscessus_ATCC_199 MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS MUL_4580|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0836|M.marinum_M -------------------------------------------------- MSMEG_0870|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_0284|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2075|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0176|M.thermoresistible__bu -------------------------------------------------- MAB_2925c|M.abscessus_ATCC_199 QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM MUL_4580|M.ulcerans_Agy99 ------------------------------MTHAFSAAGGISGQPINRVD MMAR_0836|M.marinum_M ------------------------------MTHAFSAAGGISGQPINRVD MSMEG_0870|M.smegmatis_MC2_155 -------------------------------MTAPQATPALAGRAVPRVD Mflv_0284|M.gilvum_PYR-GCK ---------------------------------MTMLEPRAIGAPTARRD Mvan_2075|M.vanbaalenii_PYR-1 -----------------------------------MVAS--VGLPVNRVE Mb0380c|M.bovis_AF2122/97 ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE Rv0373c|M.tuberculosis_H37Rv ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE TH_0176|M.thermoresistible__bu ------------------MTTLESNPAARPDDFENNDQKPCGHGRMLRKE MAB_2925c|M.abscessus_ATCC_199 VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA MUL_4580|M.ulcerans_Agy99 GPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQP--- MMAR_0836|M.marinum_M GPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQP--- MSMEG_0870|M.smegmatis_MC2_155 GRLKVTGQARYAADAEVPDALFAVLVGATVARGAVDAVHTDAARRAP--- Mflv_0284|M.gilvum_PYR-GCK GQAKVTGAAAYAYEQQVDSPAYLHPVQATIARGRVIAMDTNLARAVD--- Mvan_2075|M.vanbaalenii_PYR-1 GVDKVTGKARYSADTQVAGVAYAALVQAQIPHGRVTAESVDAAAATASAA Mb0380c|M.bovis_AF2122/97 DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHP--- Rv0373c|M.tuberculosis_H37Rv DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHP--- TH_0176|M.thermoresistible__bu DPRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDTSAAQAHP--- MAB_2925c|M.abscessus_ATCC_199 AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLP--- : * * : . . : : . . : . * MUL_4580|M.ulcerans_Agy99 -GVLAVLTDFTGVRLPFGTGQ-----------------VFFFGQPIAVVV MMAR_0836|M.marinum_M -GVLAVLTDFTGVRLPFGTGQ-----------------VFFFGQPIAVVV MSMEG_0870|M.smegmatis_MC2_155 -EVVDVITDFDGLTLKYDPQQ-----------------VCAFGQAVAVVV Mflv_0284|M.gilvum_PYR-GCK -GVLDILTVSDAP---KLADASDGELAI-----LQDATVHFRGQLIGGVV Mvan_2075|M.vanbaalenii_PYR-1 PGVLYVLTPTNCPPLQVLPKELTWDLPLERRPPLSDLTVQHVGQHMALVV Mb0380c|M.bovis_AF2122/97 -KVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQEVASVV Rv0373c|M.tuberculosis_H37Rv -KVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQEVAFVV TH_0176|M.thermoresistible__bu -KVKAVVTGADLAEKGLAWMPTLSN---DVQAVLATDKVRFQGQEVAFVV MAB_2925c|M.abscessus_ATCC_199 -GVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRFAGQRVAAVV * :: ** :. ** MUL_4580|M.ulcerans_Agy99 ATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIAD-------- MMAR_0836|M.marinum_M ATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIAD-------- MSMEG_0870|M.smegmatis_MC2_155 ATTLEAATHAASLVAVRYSTQPQLTDMDAPDASDQNPTPTRD-------- Mflv_0284|M.gilvum_PYR-GCK AETAEIAREAAALVHVEYQEKEHDAALRADHPGLYTPESVNP-------- Mvan_2075|M.vanbaalenii_PYR-1 ADSPENAVHAASLMDFDYIAAPAHLDATEVVSGGGAADDVDELI---RHG Mb0380c|M.bovis_AF2122/97 AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLE------- Rv0373c|M.tuberculosis_H37Rv AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLE------- TH_0176|M.thermoresistible__bu AEDHYSARDALELIDVDYDPLDPVVDVRRALEPDAPVIRTDLD------- MAB_2925c|M.abscessus_ATCC_199 ADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIAD * * * : . * MUL_4580|M.ulcerans_Agy99 -YVRGT----PDQVMIRAAG--------ISDLNFSIARNNHNAVELPATI MMAR_0836|M.marinum_M -YVRGT----PDQVMIRAAG--------ISDLNFSIARNNHNAVELPATI MSMEG_0870|M.smegmatis_MC2_155 -YSRGD----ADAALRGSAV--------VTDLRCSMERNNHNPMEINAVV Mflv_0284|M.gilvum_PYR-GCK SYPPD-----SDQGDVESAFPAAE---FTVDQTYRTPTEHNNPMEPHACV Mvan_2075|M.vanbaalenii_PYR-1 AYRPDHFVKLTDEKLQDFRGPRGEPPGIKVDQTYRTAVNAHYPIELSATV Mb0380c|M.bovis_AF2122/97 -GKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAV Rv0373c|M.tuberculosis_H37Rv -GKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAV TH_0176|M.thermoresistible__bu -GKTDNHCFDWETGDPAATEAAFAKADVVVEQEIVYPRVHPAPMETCGAV MAB_2925c|M.abscessus_ATCC_199 PARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSV : :* . : MUL_4580|M.ulcerans_Agy99 AKWDGDR----LTLWDKVQHINGARRSYARAFGMSEERVRLISPFVGGAF MMAR_0836|M.marinum_M AKWDGDR----LTLWDKVQHINGARRSYARAFGMSEERVRLISPFVGGAF MSMEG_0870|M.smegmatis_MC2_155 ARWEGDR----LTVWDKVQSVSGARQQYADALGVPAENVRVISPFVGGAF Mflv_0284|M.gilvum_PYR-GCK AQWTVRDGTPAVTMYDSTQGVHVVRKTLAPIFGLEPEQMRVVAPHVGGGF Mvan_2075|M.vanbaalenii_PYR-1 AQWDDGH----LTVHDCTRWITGERRVLAAYLNIPEERIRVVSPLVGGAF Mb0380c|M.bovis_AF2122/97 ADLDPVTG--KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGF Rv0373c|M.tuberculosis_H37Rv ADLDPVTG--KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGF TH_0176|M.thermoresistible__bu ADLDPVTG--KLTLWSTSQAPHAHRTLYALVAGLPEHKIRVIAPDIGGGF MAB_2925c|M.abscessus_ATCC_199 GWQDERGR---YVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGF . .: : * . .: ..:*:.:* :**.* MUL_4580|M.ulcerans_Agy99 GSAGRMWPHQLLTVFAARRMQ-LPVKLVLTRKQMYSSVGFRPTSRQRMAI MMAR_0836|M.marinum_M GSAGRMWPHQLLTAFAARRMQ-LPVKLVLTRKQMYSSVGFRPTSRQRMAI MSMEG_0870|M.smegmatis_MC2_155 GNAGQVWPHQAIAAHVARRVG-RPVKLMLTRRHLYAVTGYRPRNRQRLAI Mflv_0284|M.gilvum_PYR-GCK GSKGAPHAHDVLTVMAAQRAGGRPVKLALTRQQMFSLVGYRTPTIQRVRL Mvan_2075|M.vanbaalenii_PYR-1 GSKSFLWMHVVLCAVAAREVG-RPVKLVLTRDQMFTSTGHRPRTEQQVAL Mb0380c|M.bovis_AF2122/97 GNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGEI Rv0373c|M.tuberculosis_H37Rv GNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGEI TH_0176|M.thermoresistible__bu GNKVPIYPGYVCAIVGSLLLG-KPVKWVEDRSENLTSTGFARDYIMVGEI MAB_2925c|M.abscessus_ATCC_199 GAKQEMLTEDLVLLAVRVTGA--PVVYEFTRSDQFTIAPCRHPMRVNVTA * ** * . : . MUL_4580|M.ulcerans_Agy99 GADPSGRLMAMIHEGRTETAQYGIYEDGIVR----SPQLTYQVPNMSSTY MMAR_0836|M.marinum_M GADPSGRLMAMIHEGRTETAQYGIYEDGIVR----SPQLMYQVPNMSSTY MSMEG_0870|M.smegmatis_MC2_155 GADRSGRITAIVHEGAVEVSRYSPYVDNVTG----AASYMYQAPNMRSAL Mflv_0284|M.gilvum_PYR-GCK GADRDGRLTALVHDAIGQTATVKEFAEQTAV----TSRKMYAAANRRTSH Mvan_2075|M.vanbaalenii_PYR-1 VADAAGTIVSTEHHTLTETSTVAHFCEPAGV----SSRILYQSPRLAVTH Mb0380c|M.bovis_AF2122/97 AANRDGKILAIRSNVLADHGAFNAQAAPAKY----PAG-FFGVFTGSYDI Rv0373c|M.tuberculosis_H37Rv AANRDGKILAIRSNVLADHGAFNAQAAPAKY----PAG-FFGVFTGSYDI TH_0176|M.thermoresistible__bu AATRDGRILAIRSHVLADHGAFNGTAAPVKY----PAG-FFGVFTGSYDL MAB_2925c|M.abscessus_ATCC_199 AADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANKRVDA * * : : . : . . : MUL_4580|M.ulcerans_Agy99 RVVPLDINLPWFMRGPG---------AVTGTFALESTMDDLAHRLGIDPI MMAR_0836|M.marinum_M RVVPLDINLPWFMRGPG---------AVTGTFALESTMDDLAHRLGIDPI MSMEG_0870|M.smegmatis_MC2_155 RTVELDVHPGNQMRGPG---------HLSGNFALESAMDDLAHRLAMDPI Mflv_0284|M.gilvum_PYR-GCK RLAALDVPVPFWMRAPG---------ECPGTYAAEVAMDELAVAAGIDPI Mvan_2075|M.vanbaalenii_PYR-1 TVARIHAPTPCFMRGPG---------EAPGLFALEMAMDELAYALGRDPL Mb0380c|M.bovis_AF2122/97 EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPA Rv0373c|M.tuberculosis_H37Rv EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPA TH_0176|M.thermoresistible__bu EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELEMDPA MAB_2925c|M.abscessus_ATCC_199 QAVYTNNIPSGAFRGYG---------LGQVLFGIESALDELARNLGIDPF . . :. * : * :* ** ** MUL_4580|M.ulcerans_Agy99 ELRLRNEP--------RIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSI MMAR_0836|M.marinum_M ELRLRNEP--------RIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSI MSMEG_0870|M.smegmatis_MC2_155 ELRVRNEP--------TRDQTDNLPFSSRRLTECLRSGATAFGWSRRNPV Mflv_0284|M.gilvum_PYR-GCK QLRIRNDP--------PTDPETGKPWSGRHLVECLEVGAERFDWSSRDPE Mvan_2075|M.vanbaalenii_PYR-1 ALRMDNLA--------DVDQTDGRPWSSAHLARCYTTGARRFGWDRRPLQ Mb0380c|M.bovis_AF2122/97 ELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE Rv0373c|M.tuberculosis_H37Rv ELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE TH_0176|M.thermoresistible__bu ELRLRNLLKPDQ---FPYTSKTGWVYDSGDYETTMRKAMAMVGYDELRAE MAB_2925c|M.abscessus_ATCC_199 EFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPA :* * . :. . . MUL_4580|M.ulcerans_Agy99 P-GANRDGDSFVGIGMATAAYFTYRSK------------CAAIARISADG MMAR_0836|M.marinum_M P-GANRDGDSFVGIGMATAAYFTYRSK------------CAAIARISADG MSMEG_0870|M.smegmatis_MC2_155 P-RSVREGRQLIGLGVSAASFVTLVSP------------CAASARVRNDG Mflv_0284|M.gilvum_PYR-GCK P-GTRVLGDWLVGTGVASATYPGMAMPG-----------NAARITYSAEG Mvan_2075|M.vanbaalenii_PYR-1 S-RSLQRNGIRVGWGMATATYPGRRMP------------AACRVETDADG Mb0380c|M.bovis_AF2122/97 Q-KQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG Rv0373c|M.tuberculosis_H37Rv Q-KQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG TH_0176|M.thermoresistible__bu Q-AERRRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG MAB_2925c|M.abscessus_ATCC_199 RNGSDLPAGWKVGEGMAIAMIATVPPRG---------HVADARAELDARG :* *:: . * MUL_4580|M.ulcerans_Agy99 TAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDS-RFPPAPAH MMAR_0836|M.marinum_M TAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDS-RFPPAPAH MSMEG_0870|M.smegmatis_MC2_155 TVEILCGASDIGPGTYTAMSQVGADALGVALHRVRFQLGDS-ALPVAPAQ Mflv_0284|M.gilvum_PYR-GCK HYDVHIGAADIGTGTWTTLSQIAADALDCDLAAITLQIGDT-DLPAASVA Mvan_2075|M.vanbaalenii_PYR-1 HVRFSAATHEIGTGVRTVMTQLAADTTGLPLSQVSFESGDS-SFPDAPYS Mb0380c|M.bovis_AF2122/97 KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT Rv0373c|M.tuberculosis_H37Rv KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT TH_0176|M.thermoresistible__bu KAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTPFGLGT MAB_2925c|M.abscessus_ATCC_199 RYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGA . . * * * :*: * . : . .*: . MUL_4580|M.ulcerans_Agy99 SASRTTASVGSAVFTVANMLHDKFIRAAVTDPQSPLAGLRPEDVMVTNGH MMAR_0836|M.marinum_M SASRTTASVGSAVFTVANMLRDKFIRAAVTDPQSPLTGLRPEDVMVTNGH MSMEG_0870|M.smegmatis_MC2_155 TGSRLMASAGSSIHNVGMMLRDRFVRMAVTDPGSPLHGLAPADVEVADGR Mflv_0284|M.gilvum_PYR-GCK GGSSGMTSWGTTIVLAAQQFRRDHGNPPVIG------------------- Mvan_2075|M.vanbaalenii_PYR-1 GASQTSASVGSAVFAAAQEWRGRADALPATADGP---------------- Mb0380c|M.bovis_AF2122/97 YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG Rv0373c|M.tuberculosis_H37Rv YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG TH_0176|M.thermoresistible__bu YGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGSFRVKG MAB_2925c|M.abscessus_ATCC_199 FGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAG- .* . * : .. : . MUL_4580|M.ulcerans_Agy99 MFSTVATDGPARGESYQDLLRRRGWPALESEHTWTPDDAGKRYSTYAYGA MMAR_0836|M.marinum_M MFSTVATDGPARGESYQDLLRRRGWPALESEHTWTPDDADKRYSTYAYGA MSMEG_0870|M.smegmatis_MC2_155 MA---ARGEPARGERYEELLRRRRLDELSAELEWTPDGPHDRFSMHSFGA Mflv_0284|M.gilvum_PYR-GCK ---------------------------ATTVTEAPDPENDEVTVQ-SFGA Mvan_2075|M.vanbaalenii_PYR-1 -----------------------GRAAALSFTTASGPGPDVDTVSRSFGA Mb0380c|M.bovis_AF2122/97 DP----SAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGA Rv0373c|M.tuberculosis_H37Rv DP----SAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGA TH_0176|M.thermoresistible__bu DP----SASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYNPSNLTYPYGA MAB_2925c|M.abscessus_ATCC_199 ----------------ADLLGLTEIAASAPEPLSAVGHHEGTPRSVAFNV . .:.. MUL_4580|M.ulcerans_Agy99 VFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGMIGGIGMAL MMAR_0836|M.marinum_M VFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGMIGGIGMAL MSMEG_0870|M.smegmatis_MC2_155 VFAEVAVDEALGTVRVRRMFASYDAGRIVNPMLAHSQAIGGMVMGIGAAL Mflv_0284|M.gilvum_PYR-GCK HFVEAHVNRHTGEIRVPRMLGVFSIGRAINPRTLRSQLIGGMTMGLSMAL Mvan_2075|M.vanbaalenii_PYR-1 HFCEVEVDEQIGRATVTRWVAVMDCGRVLNPKLATNQVMGGILFGLGMAL Mb0380c|M.bovis_AF2122/97 YFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL Rv0373c|M.tuberculosis_H37Rv YFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL TH_0176|M.thermoresistible__bu YFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL MAB_2925c|M.abscessus_ATCC_199 QAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSAL . : : : . * :** .* **: .:. ** MUL_4580|M.ulcerans_Agy99 LEGTELDYRDGRVVNANISDYLVPINADVPVLDASFLPAQDTIADPIGVK MMAR_0836|M.marinum_M LEGTELDYRDGRVVNANISDYLVPVNADVPALDASFLPAQDTIADPIGVK MSMEG_0870|M.smegmatis_MC2_155 LEATHLDHRDGRIVNANMSDYLVPVNADVPDLDAEFLPGEDLIADPIGVK Mflv_0284|M.gilvum_PYR-GCK HEESVRDPRFGHVVTQDFATYHISSHADVVDIDAIWLDEVDEHLNPMGSR Mvan_2075|M.vanbaalenii_PYR-1 MEQVPHDPHTGRLLG----EYYVPTHADRPAFDISFVDSSDYGLDPIGVR Mb0380c|M.bovis_AF2122/97 MEMIAFD-EDGNCLGGSLMDYLIPTALEVPHLETGHTVTP-SPHHPIGAK Rv0373c|M.tuberculosis_H37Rv MEMIAFD-EDGNCLGGSLMDYLIPTALEVPHLETGHTVTP-SPHHPIGAK TH_0176|M.thermoresistible__bu MQMIGFD-EDGNCLGGSLMDYLIPTAMEVPTLETGFTVTP-SPHHPIGAK MAB_2925c|M.abscessus_ATCC_199 YEEILVH--DGFVSTTALRNYHIPRLVDVPDTEVYFADTY-DTFGPLGAK : . * * :. : : *:* : MUL_4580|M.ulcerans_Agy99 GLGELVIIAVPAAIANAVFNATG---KRVTDLPIRVEQLL---------- MMAR_0836|M.marinum_M GLGELVIIAVPAAIANAVFNATG---KRVTDLPIRVEQLL---------- MSMEG_0870|M.smegmatis_MC2_155 GIGELVVVGIPAAVANAVFNATG---RRVTDLPITLDKLM---------- Mflv_0284|M.gilvum_PYR-GCK GAGEIGIVGSAAAVVNAVYHATG---IRVRDLPVTLDKVLAGLP------ Mvan_2075|M.vanbaalenii_PYR-1 GIGEIGVCGVAGAIASAIHHATG---KWLRQLPITLEALLGPRDDDRED- Mb0380c|M.bovis_AF2122/97 GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP Rv0373c|M.tuberculosis_H37Rv GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP TH_0176|M.thermoresistible__bu GIGESATVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRAQPS MAB_2925c|M.abscessus_ATCC_199 SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE . .* . *:..*: .* . :*: : MUL_4580|M.ulcerans_Agy99 -- MMAR_0836|M.marinum_M -- MSMEG_0870|M.smegmatis_MC2_155 -- Mflv_0284|M.gilvum_PYR-GCK -- Mvan_2075|M.vanbaalenii_PYR-1 -- Mb0380c|M.bovis_AF2122/97 I- Rv0373c|M.tuberculosis_H37Rv I- TH_0176|M.thermoresistible__bu I- MAB_2925c|M.abscessus_ATCC_199 SS