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M. ulcerans Agy99 MUL_4580 (coxL_1)

annotation: carbon monoxyde dehydrogenase (large chain), CoxL_1
coordinates: 5077390 - 5079567
length: 725

MTHAFSAAGGISGQPINRVDGPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQPGVL
AVLTDFTGVRLPFGTGQVFFFGQPIAVVVATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIA
DYVRGTPDQVMIRAAGISDLNFSIARNNHNAVELPATIAKWDGDRLTLWDKVQHINGARRSYARAFGMSE
ERVRLISPFVGGAFGSAGRMWPHQLLTVFAARRMQLPVKLVLTRKQMYSSVGFRPTSRQRMAIGADPSGR
LMAMIHEGRTETAQYGIYEDGIVRSPQLTYQVPNMSSTYRVVPLDINLPWFMRGPGAVTGTFALESTMDD
LAHRLGIDPIELRLRNEPRIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSIPGANRDGDSFVGIGMATA
AYFTYRSKCAAIARISADGTAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDSRFPPAPAHSA
SRTTASVGSAVFTVANMLHDKFIRAAVTDPQSPLAGLRPEDVMVTNGHMFSTVATDGPARGESYQDLLRR
RGWPALESEHTWTPDDAGKRYSTYAYGAVFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGM
IGGIGMALLEGTELDYRDGRVVNANISDYLVPINADVPVLDASFLPAQDTIADPIGVKGLGELVIIAVPA
AIANAVFNATGKRVTDLPIRVEQLL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4580coxL_1-100% (725)carbon monoxyde dehydrogenase (large chain), CoxL_1
M. ulcerans Agy99MUL_0115coxL5e-5026.54% (765) carbon monoxyde dehydrogenase (large chain), CoxL
M. ulcerans Agy99MUL_0588coxL_21e-4526.19% (775) aerobic-type carbon monoxide dehydrogenase, CoxL_2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0380c-5e-4926.34% (767) carbon monoxyde dehydrogenase large subunit
M. gilvum PYR-GCKMflv_0284-1e-10133.65% (740) aldehyde oxidase and xanthine dehydrogenase, molybdopterin
M. tuberculosis H37RvRv0373c-4e-4926.34% (767) carbon monoxyde dehydrogenase large subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-3e-4427.50% (789) xanthine dehydrogenase family protein
M. marinum MMMAR_0836coxL_10.099.03% (725) carbon monoxyde dehydrogenase (large chain), CoxL_1
M. avium 104-----
M. smegmatis MC2 155MSMEG_0870-0.057.58% (719) oxidoreductase
M. thermoresistible (build 8)TH_0176-6e-5627.19% (765) PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)
M. vanbaalenii PYR-1Mvan_2075-1e-11836.70% (752) aldehyde oxidase and xanthine dehydrogenase, molybdopterin

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4580|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0836|M.marinum_M               --------------------------------------------------
MSMEG_0870|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2075|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS
                                                                                      

MUL_4580|M.ulcerans_Agy99           --------------------------------------------------
MMAR_0836|M.marinum_M               --------------------------------------------------
MSMEG_0870|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2075|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM
                                                                                      

MUL_4580|M.ulcerans_Agy99           ------------------------------MTHAFSAAGGISGQPINRVD
MMAR_0836|M.marinum_M               ------------------------------MTHAFSAAGGISGQPINRVD
MSMEG_0870|M.smegmatis_MC2_155      -------------------------------MTAPQATPALAGRAVPRVD
Mflv_0284|M.gilvum_PYR-GCK          ---------------------------------MTMLEPRAIGAPTARRD
Mvan_2075|M.vanbaalenii_PYR-1       -----------------------------------MVAS--VGLPVNRVE
Mb0380c|M.bovis_AF2122/97           ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE
Rv0373c|M.tuberculosis_H37Rv        ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE
TH_0176|M.thermoresistible__bu      ------------------MTTLESNPAARPDDFENNDQKPCGHGRMLRKE
MAB_2925c|M.abscessus_ATCC_199      VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA
                                                                                      

MUL_4580|M.ulcerans_Agy99           GPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQP---
MMAR_0836|M.marinum_M               GPLKVTGKARYAADHPIPGLVYAALVCSTVARGAVDHIATGAAMRQP---
MSMEG_0870|M.smegmatis_MC2_155      GRLKVTGQARYAADAEVPDALFAVLVGATVARGAVDAVHTDAARRAP---
Mflv_0284|M.gilvum_PYR-GCK          GQAKVTGAAAYAYEQQVDSPAYLHPVQATIARGRVIAMDTNLARAVD---
Mvan_2075|M.vanbaalenii_PYR-1       GVDKVTGKARYSADTQVAGVAYAALVQAQIPHGRVTAESVDAAAATASAA
Mb0380c|M.bovis_AF2122/97           DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHP---
Rv0373c|M.tuberculosis_H37Rv        DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHP---
TH_0176|M.thermoresistible__bu      DPRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDTSAAQAHP---
MAB_2925c|M.abscessus_ATCC_199      AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLP---
                                        : *   *  :    .  .   : :  . . :    .  *       

MUL_4580|M.ulcerans_Agy99           -GVLAVLTDFTGVRLPFGTGQ-----------------VFFFGQPIAVVV
MMAR_0836|M.marinum_M               -GVLAVLTDFTGVRLPFGTGQ-----------------VFFFGQPIAVVV
MSMEG_0870|M.smegmatis_MC2_155      -EVVDVITDFDGLTLKYDPQQ-----------------VCAFGQAVAVVV
Mflv_0284|M.gilvum_PYR-GCK          -GVLDILTVSDAP---KLADASDGELAI-----LQDATVHFRGQLIGGVV
Mvan_2075|M.vanbaalenii_PYR-1       PGVLYVLTPTNCPPLQVLPKELTWDLPLERRPPLSDLTVQHVGQHMALVV
Mb0380c|M.bovis_AF2122/97           -KVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQEVASVV
Rv0373c|M.tuberculosis_H37Rv        -KVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQEVAFVV
TH_0176|M.thermoresistible__bu      -KVKAVVTGADLAEKGLAWMPTLSN---DVQAVLATDKVRFQGQEVAFVV
MAB_2925c|M.abscessus_ATCC_199      -GVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRFAGQRVAAVV
                                      *  ::                                   ** :. **

MUL_4580|M.ulcerans_Agy99           ATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIAD--------
MMAR_0836|M.marinum_M               ATTHEAAAHAVSLVDVSYSTWPQLTDIDAPQAVGYPGRLIAD--------
MSMEG_0870|M.smegmatis_MC2_155      ATTLEAATHAASLVAVRYSTQPQLTDMDAPDASDQNPTPTRD--------
Mflv_0284|M.gilvum_PYR-GCK          AETAEIAREAAALVHVEYQEKEHDAALRADHPGLYTPESVNP--------
Mvan_2075|M.vanbaalenii_PYR-1       ADSPENAVHAASLMDFDYIAAPAHLDATEVVSGGGAADDVDELI---RHG
Mb0380c|M.bovis_AF2122/97           AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLE-------
Rv0373c|M.tuberculosis_H37Rv        AEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLE-------
TH_0176|M.thermoresistible__bu      AEDHYSARDALELIDVDYDPLDPVVDVRRALEPDAPVIRTDLD-------
MAB_2925c|M.abscessus_ATCC_199      ADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIAD
                                    *     *  *   : . *                                

MUL_4580|M.ulcerans_Agy99           -YVRGT----PDQVMIRAAG--------ISDLNFSIARNNHNAVELPATI
MMAR_0836|M.marinum_M               -YVRGT----PDQVMIRAAG--------ISDLNFSIARNNHNAVELPATI
MSMEG_0870|M.smegmatis_MC2_155      -YSRGD----ADAALRGSAV--------VTDLRCSMERNNHNPMEINAVV
Mflv_0284|M.gilvum_PYR-GCK          SYPPD-----SDQGDVESAFPAAE---FTVDQTYRTPTEHNNPMEPHACV
Mvan_2075|M.vanbaalenii_PYR-1       AYRPDHFVKLTDEKLQDFRGPRGEPPGIKVDQTYRTAVNAHYPIELSATV
Mb0380c|M.bovis_AF2122/97           -GKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAV
Rv0373c|M.tuberculosis_H37Rv        -GKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAV
TH_0176|M.thermoresistible__bu      -GKTDNHCFDWETGDPAATEAAFAKADVVVEQEIVYPRVHPAPMETCGAV
MAB_2925c|M.abscessus_ATCC_199      PARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSV
                                               :                               :*  . :

MUL_4580|M.ulcerans_Agy99           AKWDGDR----LTLWDKVQHINGARRSYARAFGMSEERVRLISPFVGGAF
MMAR_0836|M.marinum_M               AKWDGDR----LTLWDKVQHINGARRSYARAFGMSEERVRLISPFVGGAF
MSMEG_0870|M.smegmatis_MC2_155      ARWEGDR----LTVWDKVQSVSGARQQYADALGVPAENVRVISPFVGGAF
Mflv_0284|M.gilvum_PYR-GCK          AQWTVRDGTPAVTMYDSTQGVHVVRKTLAPIFGLEPEQMRVVAPHVGGGF
Mvan_2075|M.vanbaalenii_PYR-1       AQWDDGH----LTVHDCTRWITGERRVLAAYLNIPEERIRVVSPLVGGAF
Mb0380c|M.bovis_AF2122/97           ADLDPVTG--KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGF
Rv0373c|M.tuberculosis_H37Rv        ADLDPVTG--KLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGF
TH_0176|M.thermoresistible__bu      ADLDPVTG--KLTLWSTSQAPHAHRTLYALVAGLPEHKIRVIAPDIGGGF
MAB_2925c|M.abscessus_ATCC_199      GWQDERGR---YVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGF
                                    .           .:    :     *   .   .:  ..:*:.:* :**.*

MUL_4580|M.ulcerans_Agy99           GSAGRMWPHQLLTVFAARRMQ-LPVKLVLTRKQMYSSVGFRPTSRQRMAI
MMAR_0836|M.marinum_M               GSAGRMWPHQLLTAFAARRMQ-LPVKLVLTRKQMYSSVGFRPTSRQRMAI
MSMEG_0870|M.smegmatis_MC2_155      GNAGQVWPHQAIAAHVARRVG-RPVKLMLTRRHLYAVTGYRPRNRQRLAI
Mflv_0284|M.gilvum_PYR-GCK          GSKGAPHAHDVLTVMAAQRAGGRPVKLALTRQQMFSLVGYRTPTIQRVRL
Mvan_2075|M.vanbaalenii_PYR-1       GSKSFLWMHVVLCAVAAREVG-RPVKLVLTRDQMFTSTGHRPRTEQQVAL
Mb0380c|M.bovis_AF2122/97           GNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGEI
Rv0373c|M.tuberculosis_H37Rv        GNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGFARDYIMVGEI
TH_0176|M.thermoresistible__bu      GNKVPIYPGYVCAIVGSLLLG-KPVKWVEDRSENLTSTGFARDYIMVGEI
MAB_2925c|M.abscessus_ATCC_199      GAKQEMLTEDLVLLAVRVTGA--PVVYEFTRSDQFTIAPCRHPMRVNVTA
                                    *                      **     * .  : .            

MUL_4580|M.ulcerans_Agy99           GADPSGRLMAMIHEGRTETAQYGIYEDGIVR----SPQLTYQVPNMSSTY
MMAR_0836|M.marinum_M               GADPSGRLMAMIHEGRTETAQYGIYEDGIVR----SPQLMYQVPNMSSTY
MSMEG_0870|M.smegmatis_MC2_155      GADRSGRITAIVHEGAVEVSRYSPYVDNVTG----AASYMYQAPNMRSAL
Mflv_0284|M.gilvum_PYR-GCK          GADRDGRLTALVHDAIGQTATVKEFAEQTAV----TSRKMYAAANRRTSH
Mvan_2075|M.vanbaalenii_PYR-1       VADAAGTIVSTEHHTLTETSTVAHFCEPAGV----SSRILYQSPRLAVTH
Mb0380c|M.bovis_AF2122/97           AANRDGKILAIRSNVLADHGAFNAQAAPAKY----PAG-FFGVFTGSYDI
Rv0373c|M.tuberculosis_H37Rv        AANRDGKILAIRSNVLADHGAFNAQAAPAKY----PAG-FFGVFTGSYDI
TH_0176|M.thermoresistible__bu      AATRDGRILAIRSHVLADHGAFNGTAAPVKY----PAG-FFGVFTGSYDL
MAB_2925c|M.abscessus_ATCC_199      AADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANKRVDA
                                     *   * : :   .   : .                .   :         

MUL_4580|M.ulcerans_Agy99           RVVPLDINLPWFMRGPG---------AVTGTFALESTMDDLAHRLGIDPI
MMAR_0836|M.marinum_M               RVVPLDINLPWFMRGPG---------AVTGTFALESTMDDLAHRLGIDPI
MSMEG_0870|M.smegmatis_MC2_155      RTVELDVHPGNQMRGPG---------HLSGNFALESAMDDLAHRLAMDPI
Mflv_0284|M.gilvum_PYR-GCK          RLAALDVPVPFWMRAPG---------ECPGTYAAEVAMDELAVAAGIDPI
Mvan_2075|M.vanbaalenii_PYR-1       TVARIHAPTPCFMRGPG---------EAPGLFALEMAMDELAYALGRDPL
Mb0380c|M.bovis_AF2122/97           EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPA
Rv0373c|M.tuberculosis_H37Rv        EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPA
TH_0176|M.thermoresistible__bu      EAAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELEMDPA
MAB_2925c|M.abscessus_ATCC_199      QAVYTNNIPSGAFRGYG---------LGQVLFGIESALDELARNLGIDPF
                                      .  .       :. *              :  *  :* **     ** 

MUL_4580|M.ulcerans_Agy99           ELRLRNEP--------RIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSI
MMAR_0836|M.marinum_M               ELRLRNEP--------RIDQINGLPFSTRRLVDCIKQGSTDFGWHRRNSI
MSMEG_0870|M.smegmatis_MC2_155      ELRVRNEP--------TRDQTDNLPFSSRRLTECLRSGATAFGWSRRNPV
Mflv_0284|M.gilvum_PYR-GCK          QLRIRNDP--------PTDPETGKPWSGRHLVECLEVGAERFDWSSRDPE
Mvan_2075|M.vanbaalenii_PYR-1       ALRMDNLA--------DVDQTDGRPWSSAHLARCYTTGARRFGWDRRPLQ
Mb0380c|M.bovis_AF2122/97           ELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE
Rv0373c|M.tuberculosis_H37Rv        ELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE
TH_0176|M.thermoresistible__bu      ELRLRNLLKPDQ---FPYTSKTGWVYDSGDYETTMRKAMAMVGYDELRAE
MAB_2925c|M.abscessus_ATCC_199      EFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPA
                                     :*  *                .  :.          .   .        

MUL_4580|M.ulcerans_Agy99           P-GANRDGDSFVGIGMATAAYFTYRSK------------CAAIARISADG
MMAR_0836|M.marinum_M               P-GANRDGDSFVGIGMATAAYFTYRSK------------CAAIARISADG
MSMEG_0870|M.smegmatis_MC2_155      P-RSVREGRQLIGLGVSAASFVTLVSP------------CAASARVRNDG
Mflv_0284|M.gilvum_PYR-GCK          P-GTRVLGDWLVGTGVASATYPGMAMPG-----------NAARITYSAEG
Mvan_2075|M.vanbaalenii_PYR-1       S-RSLQRNGIRVGWGMATATYPGRRMP------------AACRVETDADG
Mb0380c|M.bovis_AF2122/97           Q-KQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG
Rv0373c|M.tuberculosis_H37Rv        Q-KQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG
TH_0176|M.thermoresistible__bu      Q-AERRRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTG
MAB_2925c|M.abscessus_ATCC_199      RNGSDLPAGWKVGEGMAIAMIATVPPRG---------HVADARAELDARG
                                               :* *::                        .       *

MUL_4580|M.ulcerans_Agy99           TAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDS-RFPPAPAH
MMAR_0836|M.marinum_M               TAEVCSAASDMGPGTYTSMTQIAADALGLPLQRVRFSLGDS-RFPPAPAH
MSMEG_0870|M.smegmatis_MC2_155      TVEILCGASDIGPGTYTAMSQVGADALGVALHRVRFQLGDS-ALPVAPAQ
Mflv_0284|M.gilvum_PYR-GCK          HYDVHIGAADIGTGTWTTLSQIAADALDCDLAAITLQIGDT-DLPAASVA
Mvan_2075|M.vanbaalenii_PYR-1       HVRFSAATHEIGTGVRTVMTQLAADTTGLPLSQVSFESGDS-SFPDAPYS
Mb0380c|M.bovis_AF2122/97           KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT
Rv0373c|M.tuberculosis_H37Rv        KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT
TH_0176|M.thermoresistible__bu      KAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTPFGLGT
MAB_2925c|M.abscessus_ATCC_199      RYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGA
                                       .  .    * *  *  :*: *   .     : .  .*:   .     

MUL_4580|M.ulcerans_Agy99           SASRTTASVGSAVFTVANMLHDKFIRAAVTDPQSPLAGLRPEDVMVTNGH
MMAR_0836|M.marinum_M               SASRTTASVGSAVFTVANMLRDKFIRAAVTDPQSPLTGLRPEDVMVTNGH
MSMEG_0870|M.smegmatis_MC2_155      TGSRLMASAGSSIHNVGMMLRDRFVRMAVTDPGSPLHGLAPADVEVADGR
Mflv_0284|M.gilvum_PYR-GCK          GGSSGMTSWGTTIVLAAQQFRRDHGNPPVIG-------------------
Mvan_2075|M.vanbaalenii_PYR-1       GASQTSASVGSAVFAAAQEWRGRADALPATADGP----------------
Mb0380c|M.bovis_AF2122/97           YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG
Rv0373c|M.tuberculosis_H37Rv        YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG
TH_0176|M.thermoresistible__bu      YGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGSFRVKG
MAB_2925c|M.abscessus_ATCC_199      FGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAG-
                                     .*   .  * :   ..   :      .                      

MUL_4580|M.ulcerans_Agy99           MFSTVATDGPARGESYQDLLRRRGWPALESEHTWTPDDAGKRYSTYAYGA
MMAR_0836|M.marinum_M               MFSTVATDGPARGESYQDLLRRRGWPALESEHTWTPDDADKRYSTYAYGA
MSMEG_0870|M.smegmatis_MC2_155      MA---ARGEPARGERYEELLRRRRLDELSAELEWTPDGPHDRFSMHSFGA
Mflv_0284|M.gilvum_PYR-GCK          ---------------------------ATTVTEAPDPENDEVTVQ-SFGA
Mvan_2075|M.vanbaalenii_PYR-1       -----------------------GRAAALSFTTASGPGPDVDTVSRSFGA
Mb0380c|M.bovis_AF2122/97           DP----SAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGA
Rv0373c|M.tuberculosis_H37Rv        DP----SAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGA
TH_0176|M.thermoresistible__bu      DP----SASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYNPSNLTYPYGA
MAB_2925c|M.abscessus_ATCC_199      ----------------ADLLGLTEIAASAPEPLSAVGHHEGTPRSVAFNV
                                                                      .           .:..

MUL_4580|M.ulcerans_Agy99           VFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGMIGGIGMAL
MMAR_0836|M.marinum_M               VFAEVAIDALLPTVRIRRIYACYDAGRVINPKLAHSQAIGGMIGGIGMAL
MSMEG_0870|M.smegmatis_MC2_155      VFAEVAVDEALGTVRVRRMFASYDAGRIVNPMLAHSQAIGGMVMGIGAAL
Mflv_0284|M.gilvum_PYR-GCK          HFVEAHVNRHTGEIRVPRMLGVFSIGRAINPRTLRSQLIGGMTMGLSMAL
Mvan_2075|M.vanbaalenii_PYR-1       HFCEVEVDEQIGRATVTRWVAVMDCGRVLNPKLATNQVMGGILFGLGMAL
Mb0380c|M.bovis_AF2122/97           YFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL
Rv0373c|M.tuberculosis_H37Rv        YFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL
TH_0176|M.thermoresistible__bu      YFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMAL
MAB_2925c|M.abscessus_ATCC_199      QAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSAL
                                        . :        : :     . *  :**    .*  **:  .:. **

MUL_4580|M.ulcerans_Agy99           LEGTELDYRDGRVVNANISDYLVPINADVPVLDASFLPAQDTIADPIGVK
MMAR_0836|M.marinum_M               LEGTELDYRDGRVVNANISDYLVPVNADVPALDASFLPAQDTIADPIGVK
MSMEG_0870|M.smegmatis_MC2_155      LEATHLDHRDGRIVNANMSDYLVPVNADVPDLDAEFLPGEDLIADPIGVK
Mflv_0284|M.gilvum_PYR-GCK          HEESVRDPRFGHVVTQDFATYHISSHADVVDIDAIWLDEVDEHLNPMGSR
Mvan_2075|M.vanbaalenii_PYR-1       MEQVPHDPHTGRLLG----EYYVPTHADRPAFDISFVDSSDYGLDPIGVR
Mb0380c|M.bovis_AF2122/97           MEMIAFD-EDGNCLGGSLMDYLIPTALEVPHLETGHTVTP-SPHHPIGAK
Rv0373c|M.tuberculosis_H37Rv        MEMIAFD-EDGNCLGGSLMDYLIPTALEVPHLETGHTVTP-SPHHPIGAK
TH_0176|M.thermoresistible__bu      MQMIGFD-EDGNCLGGSLMDYLIPTAMEVPTLETGFTVTP-SPHHPIGAK
MAB_2925c|M.abscessus_ATCC_199      YEEILVH--DGFVSTTALRNYHIPRLVDVPDTEVYFADTY-DTFGPLGAK
                                     :    .   *         * :.   :    :            *:* :

MUL_4580|M.ulcerans_Agy99           GLGELVIIAVPAAIANAVFNATG---KRVTDLPIRVEQLL----------
MMAR_0836|M.marinum_M               GLGELVIIAVPAAIANAVFNATG---KRVTDLPIRVEQLL----------
MSMEG_0870|M.smegmatis_MC2_155      GIGELVVVGIPAAVANAVFNATG---RRVTDLPITLDKLM----------
Mflv_0284|M.gilvum_PYR-GCK          GAGEIGIVGSAAAVVNAVYHATG---IRVRDLPVTLDKVLAGLP------
Mvan_2075|M.vanbaalenii_PYR-1       GIGEIGVCGVAGAIASAIHHATG---KWLRQLPITLEALLGPRDDDRED-
Mb0380c|M.bovis_AF2122/97           GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
Rv0373c|M.tuberculosis_H37Rv        GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
TH_0176|M.thermoresistible__bu      GIGESATVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRAQPS
MAB_2925c|M.abscessus_ATCC_199      SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE
                                    . .*      . *:..*: .* .        :*:    :           

MUL_4580|M.ulcerans_Agy99           --
MMAR_0836|M.marinum_M               --
MSMEG_0870|M.smegmatis_MC2_155      --
Mflv_0284|M.gilvum_PYR-GCK          --
Mvan_2075|M.vanbaalenii_PYR-1       --
Mb0380c|M.bovis_AF2122/97           I-
Rv0373c|M.tuberculosis_H37Rv        I-
TH_0176|M.thermoresistible__bu      I-
MAB_2925c|M.abscessus_ATCC_199      SS