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TAEQTSGEQQKPDEDPGPEPLERRRAWLHKLTPGKVVVAVVGLLVAAALGLLAALFVFSYRPDREVDAQA AGAAVSAASDGAIASLSYSPDTLDCDFSSARSHLTGEFLSYYDQFTQQIVAPAAKRKSVRTSAVVLRAAI SELHPDSAVVLLFVNQTTQSADRPEPALTSSSVLVKLTKANGNHRLIRSRLGLEPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0305 | - | - | 100% (197) | hypothetical protein MUL_0305 |
| M. ulcerans Agy99 | MUL_3859 | - | 1e-44 | 52.54% (177) | hypothetical protein MUL_3859 |
| M. ulcerans Agy99 | MUL_2863 | - | 4e-21 | 39.80% (196) | Mce associated membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1397c | - | 4e-47 | 59.38% (160) | hypothetical protein Mb1397c |
| M. gilvum PYR-GCK | Mflv_2527 | - | 2e-39 | 46.77% (186) | hypothetical protein Mflv_2527 |
| M. tuberculosis H37Rv | Rv1362c | - | 6e-48 | 60.00% (160) | hypothetical protein Rv1362c |
| M. leprae Br4923 | MLBr_02598 | - | 1e-07 | 29.29% (140) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4593c | - | 2e-09 | 22.09% (172) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_4686 | - | 1e-94 | 97.81% (183) | hypothetical protein MMAR_4686 |
| M. avium 104 | MAV_0937 | - | 2e-45 | 52.49% (181) | hypothetical protein MAV_0937 |
| M. smegmatis MC2 155 | MSMEG_4770 | - | 4e-39 | 46.39% (166) | hypothetical protein MSMEG_4770 |
| M. thermoresistible (build 8) | TH_3191 | - | 5e-38 | 51.25% (160) | PUTATIVE twin-arginine translocation pathway signal |
| M. vanbaalenii PYR-1 | Mvan_4131 | - | 4e-39 | 45.41% (185) | twin-arginine translocation pathway signal |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0305|M.ulcerans_Agy99 -MTAEQT------------------SGEQQK-------------------
MMAR_4686|M.marinum_M -MTAEQT------------------SVEQQK-------------------
Mb1397c|M.bovis_AF2122/97 -MTDDVRDVNTETTDATEVAEIDSAAGEAGDSATEAFDT-----------
Rv1362c|M.tuberculosis_H37Rv -MTDDVRDVNTETTDATEVAEIDSAAGEAGDSATEAFDT-----------
MAV_0937|M.avium_104 -MSEDNR------------------SSDAAD-------------------
Mflv_2527|M.gilvum_PYR-GCK -MSDREQ------------------TPDE-DVDATVVAEDPTPE------
Mvan_4131|M.vanbaalenii_PYR-1 -MTDENR------------------TEDAAETDAALVEGDVIADVDSTDE
MSMEG_4770|M.smegmatis_MC2_155 -MSAQDQ------------------TSDAVEAPETV--------------
TH_3191|M.thermoresistible__bu VTDEVKH------------------TADTTEKAGGVAVG-----------
MAB_4593c|M.abscessus_ATCC_199 -MADDAADKDAKNADESAVTSDAEKAESSAPSSAAVESTAEGTTEAATAE
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MUL_0305|M.ulcerans_Agy99 --------PDEDP--------GPEPLERRRAWLHKLTPGKVVVAVVGLLV
MMAR_4686|M.marinum_M --------PDESP--------GPEPLERRRAWLHKLTPGKVVVAVVGLLV
Mb1397c|M.bovis_AF2122/97 -------DSATES--------TAQKGQRHRDLWRMQVTLKPVPVILILLM
Rv1362c|M.tuberculosis_H37Rv -------DSATES--------TAQKGQRHRDLWRMQVTLKPVPVILILLM
MAV_0937|M.avium_104 -------DSADRP--------EPGRPRARRN-------VKVVPIVLISLL
Mflv_2527|M.gilvum_PYR-GCK ----DEVVTGTEP--------EPAPATPRATSRRSGRVLIGAIVAAVLML
Mvan_4131|M.vanbaalenii_PYR-1 ADDVDEAAAGREPGDDDKAEADSGAATTKPPTRRPVRGLVTAILLAVALL
MSMEG_4770|M.smegmatis_MC2_155 ----DQAVTATEP--------APAHAPSRG-VLKAIRAKTVPIMLGIALV
TH_3191|M.thermoresistible__bu --VADEAVAAAPD--------TPGDNGRDRTAWRAVLKEPSGLILLIVAL
MAB_4593c|M.abscessus_ATCC_199 VADFDAEDSEKTKDSGAVEDSDDEDISLEPDEEENPKRIRGRHWALTAAA
MLBr_02598|M.leprae_Br4923 --------------------MAAAEGGGSWRNRRAGQRTAIAVVVAAVLF
MUL_0305|M.ulcerans_Agy99 AAALGLLAALFVF-SYRPDREVDAQAAGAAVSAASDGAIASLSYSPDTLD
MMAR_4686|M.marinum_M AAALGLLAALFVF-SYRPDREVDAQAAGAAVSAASDGAIAILSYSPDTLD
Mb1397c|M.bovis_AF2122/97 LISGGATGWLYLE-QYRPDQQTDSGAARAAGAAASDGTIALLSYSPDTLD
Rv1362c|M.tuberculosis_H37Rv LISGGATGWLYLE-QYRPDQQTDSGAARAAVAAASDGTIALLSYSPDTLD
MAV_0937|M.avium_104 LISGAGTAWLYFK-EYLPDKRTDARVASAVVNAASDGTVALLSYSPDTLD
Mflv_2527|M.gilvum_PYR-GCK AGSAGLAGWLYYN-EYRPDRETDPAAAQVALEAAKTGTIALLSYSPESLD
Mvan_4131|M.vanbaalenii_PYR-1 A-SAGMAGWLYLN-DYRPDQQTDPAAAQVALDAARTGTVALLSYSPESLD
MSMEG_4770|M.smegmatis_MC2_155 A-SAALATFVYLT-QYRVDKETDPAAAEVALKAATDGTVALLSYAPESLD
TH_3191|M.thermoresistible__bu VAAAAVTASLWKF-QYRLDVQTNTDAAQVAVDAATEGTIALLSYAPETLQ
MAB_4593c|M.abscessus_ATCC_199 IVAIAIVALAAIIGRLYEEQRIEEQSSREALAAAQEFANVMINVDSAKLD
MLBr_02598|M.leprae_Br4923 VGSAAFAGAAVQP--YLADRATVAVKLEVARTAAN-AITVLWTYTPENMD
: . : . ** . . . .::
MUL_0305|M.ulcerans_Agy99 CDFSSARSHLTGEFLSYYDQFTQQIVAPAAKRKSVRTSAVVLRAAISELH
MMAR_4686|M.marinum_M RDFSSARSHLTGEFLSYYDQFTQQIVAPAAKRKSVRTSAVVLRAAISELH
Mb1397c|M.bovis_AF2122/97 QDFATARSHLAGDFLSYYDQFTQQIVAPAAKQKSLKTTAKVVRAAVSELH
Rv1362c|M.tuberculosis_H37Rv QDFATARSHLAGDFLSYYDQFTQQIVAPAAKQKSLKTTAKVVRAAVSELH
MAV_0937|M.avium_104 KDFAAAKSHLSGDFLSYYNQFTEQIVAPAAKQKSLKTNARVLGAAVSDLR
Mflv_2527|M.gilvum_PYR-GCK QDFANAKSKLTGDFLDYYTQFTEQIVTPAAKEKSVKTAASVVRAGVSQIA
Mvan_4131|M.vanbaalenii_PYR-1 QDFANAKAKLTGEFLSYYTQFTEQIVTPAAKEKSVKTAASVVRAAVADIQ
MSMEG_4770|M.smegmatis_MC2_155 QDFATAKTHLTGDFLSYYTDFTTKVVAPAAQQKKVKTKATVVNGAVSEIK
TH_3191|M.thermoresistible__bu EDFAAAKEHLTGEFLDYYTEFTDTVVTPAAMEKQVSTSANVVKAAISEIH
MAB_4593c|M.abscessus_ATCC_199 ESSNKTLERSTGDFKQKYSE-SSTTLRQVMIENKAKATGVVVDSAVKSAA
MLBr_02598|M.leprae_Br4923 TLADRAATYVSGDFGAQYRKFVDAIVGPNK-QAKITNSTEVTGVAVESLD
: :*:* * . : . . * .: .
MUL_0305|M.ulcerans_Agy99 PDSAVVLLFVNQTTQSADRPEPALTSSSVLVKLTKANGNHRLIRSRLGLE
MMAR_4686|M.marinum_M PDSAVVLLFVNQTTQSADRPEPALTSSSVLVKLTKANG-KWLISS---FD
Mb1397c|M.bovis_AF2122/97 PDSAVVLVFVDQSTTSKDSPNPSMAASSVMVTLAKVDG-NWLITK---FT
Rv1362c|M.tuberculosis_H37Rv PDSAVVLVFVDQSTTSKDSPNPSMAASSVMVTLAKVDG-NWLITK---FT
MAV_0937|M.avium_104 PDSAVVLVLVDQSTTSKDNPDPAMASSSVLVSLTKVNG-KWLITK---FD
Mflv_2527|M.gilvum_PYR-GCK ADSAEVLVFINQTTTSKENPDGAFAASSVKVGMKKIDG-NWLIAS---FD
Mvan_4131|M.vanbaalenii_PYR-1 PESAEVLVFINQTTTSKENPDGAFAASSVKVGLKKIDG-NWLIES---FD
MSMEG_4770|M.smegmatis_MC2_155 PESAVVLLFINQTTTSQEIPDGSFATSSVKVGLTKIDG-NWLIST---FD
TH_3191|M.thermoresistible__bu PDSAVVLVFLNQMTTSKENPDGAFAASSVKVGLKKVDG-RWLIEA---FD
MAB_4593c|M.abscessus_ATCC_199 PDKVEVLLFIDQAVSNVAIPDARMDRSRVQITMQKVDG-RWLASD---VE
MLBr_02598|M.leprae_Br4923 ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTRMTTIT
.... .:: : . : : * .. . * .
MUL_0305|M.ulcerans_Agy99 PV------
MMAR_4686|M.marinum_M PV------
Mb1397c|M.bovis_AF2122/97 PV------
Rv1362c|M.tuberculosis_H37Rv PV------
MAV_0937|M.avium_104 PV------
Mflv_2527|M.gilvum_PYR-GCK PV------
Mvan_4131|M.vanbaalenii_PYR-1 PV------
MSMEG_4770|M.smegmatis_MC2_155 PV------
TH_3191|M.thermoresistible__bu PV------
MAB_4593c|M.abscessus_ATCC_199 LT------
MLBr_02598|M.leprae_Br4923 SLDLTPQL