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IGISQVEAVMTIELQRPERRNALNSQLVEELREAIQKAGDGSVRAVVLTGQGTAFCAGADLSGDAFAADY PDRLIELHRVMDAAPMPVIGAVNGPAIGAGLQLAMQCDLRVVAPEAFFQFPTSKYGLALDNWSIRRLSSL VGHGRARAMLLTAEKLTAETALHTGMANRIGTLADAQSWAAEIAGLAPLAIQHAKRVLNDDGSIEQPWPE HKELFDKAWGSQDVIEAQVARVEKRPPKFQGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0236 | echA6 | - | 100% (243) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 3e-25 | 30.28% (251) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1114 | echA1 | 3e-24 | 29.67% (246) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0929 | echA6 | 1e-127 | 90.53% (243) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1755 | - | 3e-96 | 69.26% (244) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0905 | echA6 | 1e-127 | 90.53% (243) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02118 | echA6 | 1e-122 | 87.04% (247) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0959 | - | 2e-89 | 67.62% (244) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4625 | echA6 | 1e-136 | 99.59% (243) | enoyl-CoA hydratase EchA6 |
| M. avium 104 | MAV_1028 | - | 1e-124 | 88.07% (243) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5639 | - | 1e-104 | 74.07% (243) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_0094 | - | 1e-103 | 76.50% (234) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4992 | - | 3e-99 | 72.54% (244) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1755|M.gilvum_PYR-GCK --MIGVTRDGHVMTVELQRPERRNALNVEIVDGLRDAIEKAA----TEDV
Mvan_4992|M.vanbaalenii_PYR-1 MLMIGVTRDGNVMTLELQRPERRNALNAELVDGLREAIEKAA----AEEV
MSMEG_5639|M.smegmatis_MC2_155 --MIGVTRDGNVLTLELQRPERRNALNCELVDSLREAVENAA----SEDI
TH_0094|M.thermoresistible__bu -----------VTTLELQRPERRNALNTELVDSLREAVQAAA----AEDT
MUL_0236|M.ulcerans_Agy99 --MIGISQVEAVMTIELQRPERRNALNSQLVEELREAIQKAG----DGSV
MMAR_4625|M.marinum_M --MIGISQVEAVMTIELQRPERRNALNSQLVEELREAIQKAG----DGSV
Mb0929|M.bovis_AF2122/97 --MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAG----DGSA
Rv0905|M.tuberculosis_H37Rv --MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAG----DGSA
MLBr_02118|M.leprae_Br4923 --MIGITQAEGVMTIELQRPERRNALNSQLIEKLREAVQKASSADSEVST
MAV_1028|M.avium_104 --MIGVTRAEAVLTIELQRPERRNALNSQLVEELREAVLKAG----DGST
MAB_0959|M.abscessus_ATCC_1997 --MIGVTSDGPVTTIELQRPERRNAVTYELALAFAEEVKKAA-----ETA
* *:**********:. :: : : : *.
Mflv_1755|M.gilvum_PYR-GCK RAIVLTGAGHVFSSGADLSGGHGVADELPEKAKALNVAIDRAPVPVIGAI
Mvan_4992|M.vanbaalenii_PYR-1 RAMVLTGAGHVFSSGADLSGGQGVADELPDKARALNLAIDRAPFPVIGAV
MSMEG_5639|M.smegmatis_MC2_155 RAIVLTGQGSVFSAGADLSG-DAFAAELPDKATALNLAIDKAPVPVIGAI
TH_0094|M.thermoresistible__bu RVIVLTGQGSVFCAGADLSG-DVFAADFPDKAIALNKAIDAVPIPVIAAI
MUL_0236|M.ulcerans_Agy99 RAVVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHRVMDAAPMPVIGAV
MMAR_4625|M.marinum_M RAVVLTGQGTAFCAGADLSG-DAFAAGYPDRLIELHRVMDAAPMPVIGAV
Mb0929|M.bovis_AF2122/97 RAIVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHKAMDASPMPVVGAI
Rv0905|M.tuberculosis_H37Rv RAIVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHKAMDASPMPVVGAI
MLBr_02118|M.leprae_Br4923 RVIVLTGQGTVFCAGADLSG-DAFAADYPDRLIELHRVMDAVPMPVIGAI
MAV_1028|M.avium_104 RAIVLTGQGTVFCAGADLSG-DAFAADYPDRLIELHKVLDATPIPVIGAI
MAB_0959|M.abscessus_ATCC_1997 RAIVVTGQGTSFCAGADLSSGAPDPDKFADAWQHSIKSVDAADIPVIAAV
*.:*:** * *.:*****. . .: :* .**:.*:
Mflv_1755|M.gilvum_PYR-GCK NGPAIGAGVILSMICDLRVVAPDAYFQFPVAKYGIALDNWSIRRLTSLVG
Mvan_4992|M.vanbaalenii_PYR-1 NGPAIGAGVILSMICDLRVVAPEAYFQFPVAKYGIALDNWSIRRLTSLVG
MSMEG_5639|M.smegmatis_MC2_155 NGPAIGAGVILAMICDLRVVVPEAYFQFPVAKYGLALDNWSIRRLTSLVG
TH_0094|M.thermoresistible__bu NGPAIGAGVQLAMICDLRVVAPEAFFQFPVAKYGLALDNWSIRRLTTLVG
MUL_0236|M.ulcerans_Agy99 NGPAIGAGLQLAMQCDLRVVAPEAFFQFPTSKYGLALDNWSIRRLSSLVG
MMAR_4625|M.marinum_M NGPAIGAGLQLAMQCDLRVVAPEAFFQFPTSKYGLALDNWSIRRLSSLVG
Mb0929|M.bovis_AF2122/97 NGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVG
Rv0905|M.tuberculosis_H37Rv NGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVG
MLBr_02118|M.leprae_Br4923 NGPAIGAGLQLAMQCDLRVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVG
MAV_1028|M.avium_104 NGPAIGAGLQLAMQCDLRVVSPDAFFQFPTSKYGLALDNWSIRRLSTLVG
MAB_0959|M.abscessus_ATCC_1997 NGPAIGAGVMLAMVADLRVVSETARFQFPVAKYGIALDNWSIRRLTSLVG
********: *:* .***** * ****.:***:**********::***
Mflv_1755|M.gilvum_PYR-GCK AGRARGMLLAAERLTADVALQTGMANRIGTLADAQAWAGEIAGFAPLALQ
Mvan_4992|M.vanbaalenii_PYR-1 AGRARGMLLAAERLTADMALHTGMANRIGTLADAQAWAQEIAGFAPLALQ
MSMEG_5639|M.smegmatis_MC2_155 YGRARGMLLAAEKLDAETALQTGMANRIGTLADAQKWAAEIAGFAPLALQ
TH_0094|M.thermoresistible__bu YGRARGMLLAAEKLSAETALQTGMANRLGTLADAQQWAAEIAQLAPLALR
MUL_0236|M.ulcerans_Agy99 HGRARAMLLTAEKLTAETALHTGMANRIGTLADAQSWAAEIAGLAPLAIQ
MMAR_4625|M.marinum_M HGRARAMLLTAEKLTAETALHTGMANRIGTLADAQSWAAEIAGLAPLAIQ
Mb0929|M.bovis_AF2122/97 HGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQ
Rv0905|M.tuberculosis_H37Rv HGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQ
MLBr_02118|M.leprae_Br4923 HGRARAMLLTAEKLTADIALQTGMANRIGALADAQAWAAEVTGLAPLAIQ
MAV_1028|M.avium_104 HGRARAMLLAAEKLTADVALQTGMANRIGTLADAQAWAAEIAGLAPLAIA
MAB_0959|M.abscessus_ATCC_1997 YGRARAMLLAAEPLDAQTALQTGMANRIGELADAQAWAAELAGFAPLALK
****.***:** * *: **:******:* ***** ** *:: :****:
Mflv_1755|M.gilvum_PYR-GCK HAKRVLNDDGAYEEPWPAHKELYDRAWTSEDIIEAQVARIEKRPPRFKGA
Mvan_4992|M.vanbaalenii_PYR-1 HAKRVLNDDGAYEEPWPAHQELFDRAWSSQDIIEAQVARIEKRPPRFQGA
MSMEG_5639|M.smegmatis_MC2_155 HAKRVLNDDGAYEEPWPAHKELFDRAWKSPDVIEAQVARIEKRPPRFTGA
TH_0094|M.thermoresistible__bu HAKRVLNDDGAFEEQRPEHKELFDLAWGSQDVIEAQVARMEKRPPVFRGA
MUL_0236|M.ulcerans_Agy99 HAKRVLNDDGSIEQPWPEHKELFDKAWGSQDVIEAQVARVEKRPPKFQGA
MMAR_4625|M.marinum_M HAKRVLNDDGSIEQPWPEHKELFDKAWGSQDVIEAQVARVEKRPPKFQGA
Mb0929|M.bovis_AF2122/97 HAKRVLNDDGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
Rv0905|M.tuberculosis_H37Rv HAKRVLNDDGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
MLBr_02118|M.leprae_Br4923 HAKRVLNDDGSIEEAWPEHKKLFDKAWTSQDVIEAQVARVEKRPPKFQGA
MAV_1028|M.avium_104 HAKRVLNDDGAIEEAWPVHKELFDKAWGSQDVIEAQVARIEKRPPKFQGA
MAB_0959|M.abscessus_ATCC_1997 HAKRVLNDDGAFEDQWPEHKELFDKAWGSQDIIEAQVARIQKRPPNFQGA
**********: *: * *::*:* ** * *:*******::**** * **