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M. bovis AF2122 / 97 Mb0929 (echA6)

annotation: enoyl-CoA hydratase
coordinates: 1008672 - 1009403
length: 243

MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAGDGSARAIVLTGQGTAFCAGADLSGDAFAAD
YPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSS
LVGHGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQHAKRVLNDDGAIEEAWP
AHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0929echA6-100% (243)enoyl-CoA hydratase
M. bovis AF2122 / 97Mb1099cechA86e-2731.08% (251) enoyl-CoA hydratase
M. bovis AF2122 / 97Mb2511echA143e-2238.79% (165) enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1755-1e-9570.08% (244) enoyl-CoA hydratase
M. tuberculosis H37RvRv0905echA61e-136100.00% (243) enoyl-CoA hydratase
M. leprae Br4923MLBr_02118echA61e-12085.83% (247) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_0959-5e-8967.21% (244) enoyl-CoA hydratase
M. marinum MMMAR_4625echA61e-12690.12% (243) enoyl-CoA hydratase EchA6
M. avium 104MAV_1028-1e-12690.53% (243) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5639-1e-10174.07% (243) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_0094-1e-10276.50% (234) enoyl-CoA hydratase
M. ulcerans Agy99MUL_0236echA61e-12790.53% (243) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4992-4e-9770.90% (244) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1755|M.gilvum_PYR-GCK          --MIGVTRDGHVMTVELQRPERRNALNVEIVDGLRDAIEKAA----TEDV
Mvan_4992|M.vanbaalenii_PYR-1       MLMIGVTRDGNVMTLELQRPERRNALNAELVDGLREAIEKAA----AEEV
MSMEG_5639|M.smegmatis_MC2_155      --MIGVTRDGNVLTLELQRPERRNALNCELVDSLREAVENAA----SEDI
TH_0094|M.thermoresistible__bu      -----------VTTLELQRPERRNALNTELVDSLREAVQAAA----AEDT
Mb0929|M.bovis_AF2122/97            --MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAG----DGSA
Rv0905|M.tuberculosis_H37Rv         --MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAG----DGSA
MMAR_4625|M.marinum_M               --MIGISQVEAVMTIELQRPERRNALNSQLVEELREAIQKAG----DGSV
MUL_0236|M.ulcerans_Agy99           --MIGISQVEAVMTIELQRPERRNALNSQLVEELREAIQKAG----DGSV
MLBr_02118|M.leprae_Br4923          --MIGITQAEGVMTIELQRPERRNALNSQLIEKLREAVQKASSADSEVST
MAV_1028|M.avium_104                --MIGVTRAEAVLTIELQRPERRNALNSQLVEELREAVLKAG----DGST
MAB_0959|M.abscessus_ATCC_1997      --MIGVTSDGPVTTIELQRPERRNAVTYELALAFAEEVKKAA-----ETA
                                               * *:**********:. ::   : : :  *.        

Mflv_1755|M.gilvum_PYR-GCK          RAIVLTGAGHVFSSGADLSGGHGVADELPEKAKALNVAIDRAPVPVIGAI
Mvan_4992|M.vanbaalenii_PYR-1       RAMVLTGAGHVFSSGADLSGGQGVADELPDKARALNLAIDRAPFPVIGAV
MSMEG_5639|M.smegmatis_MC2_155      RAIVLTGQGSVFSAGADLSG-DAFAAELPDKATALNLAIDKAPVPVIGAI
TH_0094|M.thermoresistible__bu      RVIVLTGQGSVFCAGADLSG-DVFAADFPDKAIALNKAIDAVPIPVIAAI
Mb0929|M.bovis_AF2122/97            RAIVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHKAMDASPMPVVGAI
Rv0905|M.tuberculosis_H37Rv         RAIVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHKAMDASPMPVVGAI
MMAR_4625|M.marinum_M               RAVVLTGQGTAFCAGADLSG-DAFAAGYPDRLIELHRVMDAAPMPVIGAV
MUL_0236|M.ulcerans_Agy99           RAVVLTGQGTAFCAGADLSG-DAFAADYPDRLIELHRVMDAAPMPVIGAV
MLBr_02118|M.leprae_Br4923          RVIVLTGQGTVFCAGADLSG-DAFAADYPDRLIELHRVMDAVPMPVIGAI
MAV_1028|M.avium_104                RAIVLTGQGTVFCAGADLSG-DAFAADYPDRLIELHKVLDATPIPVIGAI
MAB_0959|M.abscessus_ATCC_1997      RAIVVTGQGTSFCAGADLSSGAPDPDKFADAWQHSIKSVDAADIPVIAAV
                                    *.:*:** *  *.:*****.    .   .:        :*   .**:.*:

Mflv_1755|M.gilvum_PYR-GCK          NGPAIGAGVILSMICDLRVVAPDAYFQFPVAKYGIALDNWSIRRLTSLVG
Mvan_4992|M.vanbaalenii_PYR-1       NGPAIGAGVILSMICDLRVVAPEAYFQFPVAKYGIALDNWSIRRLTSLVG
MSMEG_5639|M.smegmatis_MC2_155      NGPAIGAGVILAMICDLRVVVPEAYFQFPVAKYGLALDNWSIRRLTSLVG
TH_0094|M.thermoresistible__bu      NGPAIGAGVQLAMICDLRVVAPEAFFQFPVAKYGLALDNWSIRRLTTLVG
Mb0929|M.bovis_AF2122/97            NGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVG
Rv0905|M.tuberculosis_H37Rv         NGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVG
MMAR_4625|M.marinum_M               NGPAIGAGLQLAMQCDLRVVAPEAFFQFPTSKYGLALDNWSIRRLSSLVG
MUL_0236|M.ulcerans_Agy99           NGPAIGAGLQLAMQCDLRVVAPEAFFQFPTSKYGLALDNWSIRRLSSLVG
MLBr_02118|M.leprae_Br4923          NGPAIGAGLQLAMQCDLRVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVG
MAV_1028|M.avium_104                NGPAIGAGLQLAMQCDLRVVSPDAFFQFPTSKYGLALDNWSIRRLSTLVG
MAB_0959|M.abscessus_ATCC_1997      NGPAIGAGVMLAMVADLRVVSETARFQFPVAKYGIALDNWSIRRLTSLVG
                                    ********: *:* .*****   * ****.:***:**********::***

Mflv_1755|M.gilvum_PYR-GCK          AGRARGMLLAAERLTADVALQTGMANRIGTLADAQAWAGEIAGFAPLALQ
Mvan_4992|M.vanbaalenii_PYR-1       AGRARGMLLAAERLTADMALHTGMANRIGTLADAQAWAQEIAGFAPLALQ
MSMEG_5639|M.smegmatis_MC2_155      YGRARGMLLAAEKLDAETALQTGMANRIGTLADAQKWAAEIAGFAPLALQ
TH_0094|M.thermoresistible__bu      YGRARGMLLAAEKLSAETALQTGMANRLGTLADAQQWAAEIAQLAPLALR
Mb0929|M.bovis_AF2122/97            HGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQ
Rv0905|M.tuberculosis_H37Rv         HGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQ
MMAR_4625|M.marinum_M               HGRARAMLLTAEKLTAETALHTGMANRIGTLADAQSWAAEIAGLAPLAIQ
MUL_0236|M.ulcerans_Agy99           HGRARAMLLTAEKLTAETALHTGMANRIGTLADAQSWAAEIAGLAPLAIQ
MLBr_02118|M.leprae_Br4923          HGRARAMLLTAEKLTADIALQTGMANRIGALADAQAWAAEVTGLAPLAIQ
MAV_1028|M.avium_104                HGRARAMLLAAEKLTADVALQTGMANRIGTLADAQAWAAEIAGLAPLAIA
MAB_0959|M.abscessus_ATCC_1997      YGRARAMLLAAEPLDAQTALQTGMANRIGELADAQAWAAELAGFAPLALK
                                     ****.***:** * *: **:******:* ***** ** *:: :****: 

Mflv_1755|M.gilvum_PYR-GCK          HAKRVLNDDGAYEEPWPAHKELYDRAWTSEDIIEAQVARIEKRPPRFKGA
Mvan_4992|M.vanbaalenii_PYR-1       HAKRVLNDDGAYEEPWPAHQELFDRAWSSQDIIEAQVARIEKRPPRFQGA
MSMEG_5639|M.smegmatis_MC2_155      HAKRVLNDDGAYEEPWPAHKELFDRAWKSPDVIEAQVARIEKRPPRFTGA
TH_0094|M.thermoresistible__bu      HAKRVLNDDGAFEEQRPEHKELFDLAWGSQDVIEAQVARMEKRPPVFRGA
Mb0929|M.bovis_AF2122/97            HAKRVLNDDGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
Rv0905|M.tuberculosis_H37Rv         HAKRVLNDDGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
MMAR_4625|M.marinum_M               HAKRVLNDDGSIEQPWPEHKELFDKAWGSQDVIEAQVARVEKRPPKFQGA
MUL_0236|M.ulcerans_Agy99           HAKRVLNDDGSIEQPWPEHKELFDKAWGSQDVIEAQVARVEKRPPKFQGA
MLBr_02118|M.leprae_Br4923          HAKRVLNDDGSIEEAWPEHKKLFDKAWTSQDVIEAQVARVEKRPPKFQGA
MAV_1028|M.avium_104                HAKRVLNDDGAIEEAWPVHKELFDKAWGSQDVIEAQVARIEKRPPKFQGA
MAB_0959|M.abscessus_ATCC_1997      HAKRVLNDDGAFEDQWPEHKELFDKAWGSQDIIEAQVARIQKRPPNFQGA
                                    **********: *:  * *::*:* ** * *:*******::**** * **