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M. ulcerans Agy99 MUL_0064 (ino1)

annotation: myo-inositol-1-phosphate synthase Ino1
coordinates: 61287 - 62405
length: 372

SEKKPLGAPGAQPEVRVAIVGVGNCASSLVQGVEYYQNADDNSMVPGLMHVRFGPYHVRDVKFVAAFDVD
AKKVGFDLSDAIFASENNTIKIADVAPTNVVVQRGPTLDGIGKYYADTIELSDDEPVDVVKVLKDNKVDV
LVSYLPVGSEEADKFYAQCAIDAGVAFVNALPVFIASDPAWAKKFKDAGVPIIGDDIKSQVGATITHRVM
AKLFEDRGVTLDRTYQLNVGGNMDFKNMLERERLESKKVSKTQAVTSNLTGSLAGKVEDKNVHIGPSDHV
AWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGIIIDAVRAAKIAKDRGIGGPVIPASAYLMKS
PPKQLADDVARTQLEEFIIEG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0064ino1-100% (372)myo-inositol-1-phosphate synthase Ino1
M. ulcerans Agy99MUL_1692-6e-0824.88% (205) myo-inositol-1-phosphate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0047cino10.088.92% (370) myo-inositol-1-phosphate synthase INO1 (inositol 1-phosphate
M. gilvum PYR-GCKMflv_0867-0.090.22% (358) myo-inositol-1-phosphate synthase
M. tuberculosis H37RvRv0046cino10.088.65% (370) myo-inositol-1-phosphate synthase INO1 (inositol 1-phosphate
M. leprae Br4923MLBr_02692-0.085.18% (371) hypothetical protein MLBr_02692
M. abscessus ATCC 19977MAB_4907-0.092.11% (355) myo-inositol-1-phosphate synthase
M. marinum MMMAR_0065ino10.099.73% (372) myo-inositol-1-phosphate synthase Ino1
M. avium 104MAV_0067-0.087.37% (372) myo-inositol-1-phosphate synthase
M. smegmatis MC2 155MSMEG_6904-0.091.27% (355) myo-inositol-1-phosphate synthase
M. thermoresistible (build 8)TH_1311-1e-17785.43% (357) MYO-INOSITOL-1-PHOSPHATE SYNTHASE INO1 (Inositol 1-phosphate
M. vanbaalenii PYR-1Mvan_6040-0.090.78% (358) myo-inositol-1-phosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_0064|M.ulcerans_Agy99           MSEKKPLGAPGAQPEVRVAIVGVGNCASSLVQGVEYYQNADDNSMVPGLM
MMAR_0065|M.marinum_M               MSEKKPLGAPGAQPEVRVAIVGVGNCASSLVQGVEYYQNADDNSMVPGLM
Mflv_0867|M.gilvum_PYR-GCK          MT--------ASN-DVRVAIVGVGNCASSLVQGVQYYKDADENASVPGLM
Mvan_6040|M.vanbaalenii_PYR-1       MT--------ASN-DVRVAIVGVGNCASSLVQGVQYYKDADENATVPGLM
MSMEG_6904|M.smegmatis_MC2_155      MS--------EHAGEIRVAIVGVGNCASSLVQGVQYYRNADENTTVPGLM
MAB_4907|M.abscessus_ATCC_1997      MS--------NTSSEVRVAIVGVGNCASSLVQGVQYYQDADENSTVPGLM
Mb0047c|M.bovis_AF2122/97           MSEHQSLPAPEASTEVRVAIVGVGNCASSLVQGVEYYYNADDTSTVPGLM
Rv0046c|M.tuberculosis_H37Rv        MSEHQSLPAPEASTEVRVAIVGVGNCASSLVQGVEYYYNADDTSTVPGLM
MLBr_02692|M.leprae_Br4923          MSEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLM
MAV_0067|M.avium_104                MSDHQPPQAEDAQSEVRVAIVGVGNCASSLVQGVQYYFDADENSTVPGLM
TH_1311|M.thermoresistible__bu      MSEQK---------DIRVAIVGVGNCAASLVQGVEYYKDADENATVPGLM
                                    *:            ::***********:*****::** :**:.: *****

MUL_0064|M.ulcerans_Agy99           HVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTN
MMAR_0065|M.marinum_M               HVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTN
Mflv_0867|M.gilvum_PYR-GCK          HVKLGAYHVRDVKFVAAFDVDAKKVGFDLSEAIFASENNTIKIADVPPTD
Mvan_6040|M.vanbaalenii_PYR-1       HVKLGPYHVRDVKFVAAFDVDAKKVGFDLSEAIFASENNTIKIADVPPTD
MSMEG_6904|M.smegmatis_MC2_155      HVKFGPYHVRDVNFVAAFDVDAKKVGFDLSEAIFASENNTIKIADVPPTD
MAB_4907|M.abscessus_ATCC_1997      HVKFGPYHVRDVKFVAAFDVDAKKVGFDLSEAISASENNTIKIADVPPTD
Mb0047c|M.bovis_AF2122/97           HVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTN
Rv0046c|M.tuberculosis_H37Rv        HVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTN
MLBr_02692|M.leprae_Br4923          HVRFGPYHVRDVKFVAAFDVDAKKVGVDLSDAIFTSENNTIKIADVPPTN
MAV_0067|M.avium_104                HVKFGQYHVRDVKFVAAFDVDAKKVGFDLSEAIFASENNTIKIADVPPTN
TH_1311|M.thermoresistible__bu      HVRFGPYHVRDVNFVAAFDVDAKKVGFDLSEAIVASENNTIKIADVPPTD
                                    **::* ******:*************.***:** :***********.**:

MUL_0064|M.ulcerans_Agy99           VVVQRGPTLDGIGKYYADTIELSDDEPVDVVKVLKDNKVDVLVSYLPVGS
MMAR_0065|M.marinum_M               AVVQRGPTLDGIGKYYADTIELSDDEPVDVVKVLKDNKVDVLVSYLPVGS
Mflv_0867|M.gilvum_PYR-GCK          VVVQRGPTLDGIGKYYADTIEISDADAVDVVKVLKDAKVDVMVSYLPVGS
Mvan_6040|M.vanbaalenii_PYR-1       VVVQRGPTLDGIGKYYADTIEISDAEAVDVVKVLKDAKVDVLVSYLPVGS
MSMEG_6904|M.smegmatis_MC2_155      VIVQRGPTLDGIGKYYADTIEVSDAEPVDVVKVLKEAEVDVLVSYLPVGS
MAB_4907|M.abscessus_ATCC_1997      VIVQRGPTLDGIGKYYADTIEVSDSEPVDVVKVLKDNNVDVLVSYLPVGS
Mb0047c|M.bovis_AF2122/97           VIVQRGPTLDGIGKYYADTIELSDAEPVDVVQALKEAKVDVLVSYLPVGS
Rv0046c|M.tuberculosis_H37Rv        VIVQRGPTLDGIGKYYADTIELSDAEPVDVVQALKEAKVDVLVSYLPVGS
MLBr_02692|M.leprae_Br4923          VVVQRGPTLDGIGKYYTDTIELSDVPPVDVVQALTEAKTDVLVSYLPVGS
MAV_0067|M.avium_104                VTVQRGPTLDGIGKYYADTIEVSDAEPVDVVQVLKEAKVDVLVSYLPVGS
TH_1311|M.thermoresistible__bu      VVVQRGPTLDGIGKYYADTIEVSDAEPVDVVKALKEAEVDVLVSYLPVGS
                                    . **************:****:**  .****:.*.: :.**:********

MUL_0064|M.ulcerans_Agy99           EEADKFYAQCAIDAGVAFVNALPVFIASDPAWAKKFKDAGVPIIGDDIKS
MMAR_0065|M.marinum_M               EEADKFYAQCAIDAGVAFVNALPVFIASDPAWAKKFKDAGVPIIGDDIKS
Mflv_0867|M.gilvum_PYR-GCK          EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKS
Mvan_6040|M.vanbaalenii_PYR-1       EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKS
MSMEG_6904|M.smegmatis_MC2_155      EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKS
MAB_4907|M.abscessus_ATCC_1997      EEADKFYAQCAIDAKVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKS
Mb0047c|M.bovis_AF2122/97           EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFTDAGVPIVGDDIKS
Rv0046c|M.tuberculosis_H37Rv        EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFTDARVPIVGDDIKS
MLBr_02692|M.leprae_Br4923          EEADKFYAQCAINARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKS
MAV_0067|M.avium_104                EEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFTDAGVPIVGDDIKS
TH_1311|M.thermoresistible__bu      EEADKFYAQCCIDAGVAFVNALPVFIASDPVWAKKFADAGVPIVGDDIKS
                                    **********.*:* ***************.***** ** ***:******

MUL_0064|M.ulcerans_Agy99           QVGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFKNMLERERLESKKV
MMAR_0065|M.marinum_M               QVGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFKNMLERERLESKKV
Mflv_0867|M.gilvum_PYR-GCK          QIGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFLNMLERTRLESKKV
Mvan_6040|M.vanbaalenii_PYR-1       QIGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFLNMLERSRLESKKV
MSMEG_6904|M.smegmatis_MC2_155      QVGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFLNMLERSRLESKKV
MAB_4907|M.abscessus_ATCC_1997      QVGATITHRVMAKLFEDRGVTLDRTYQLNVGGNMDFKNMLERERLESKKV
Mb0047c|M.bovis_AF2122/97           QVGATITHRVLAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKI
Rv0046c|M.tuberculosis_H37Rv        QVGATITHRVLAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKI
MLBr_02692|M.leprae_Br4923          QVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERVQSKKI
MAV_0067|M.avium_104                QIGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKI
TH_1311|M.thermoresistible__bu      QIGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKI
                                    *:********:********* **** ********** ***** *::***:

MUL_0064|M.ulcerans_Agy99           SKTQAVTSNLTGSLAGKVEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFG
MMAR_0065|M.marinum_M               SKTQAVTSNLTGSLAGKVEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFG
Mflv_0867|M.gilvum_PYR-GCK          SKTQAVTSNLSGSLAGKVEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFG
Mvan_6040|M.vanbaalenii_PYR-1       SKTQAVTSNLSGSLAGKIEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFG
MSMEG_6904|M.smegmatis_MC2_155      SKTQAVTSNLSGALAGKVEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFG
MAB_4907|M.abscessus_ATCC_1997      SKTQAVTSNLNGSLADKVYDKNVHIGPSDYVAWLDDRKWAYVRLEGRAFG
Mb0047c|M.bovis_AF2122/97           SKTQAVTSNLKREFK----TKDVHIGPSDHVGWLDDRKWAYVRLEGRAFG
Rv0046c|M.tuberculosis_H37Rv        SKTQAVTSNLKREFK----TKDVHIGPSDHVGWLDDRKWAYVRLEGRAFG
MLBr_02692|M.leprae_Br4923          SKTQAVTSNVHREFN----TKDIHIGPSDHVGWLDDRKWAYVRLEGRGFG
MAV_0067|M.avium_104                SKTQAVTSNLQREFK----TKDVHIGPSDHVSWLDDRKWAYVRLEGRAFG
TH_1311|M.thermoresistible__bu      SKTQAVTSNLQKEFK----TKDVHIGPSDHVGWLDDRKWAYVRLEGRAFG
                                    *********:   :      *::******:*.***************.**

MUL_0064|M.ulcerans_Agy99           DVPLNLEYKLEVWDSPNSAGIIIDAVRAAKIAKDRGIGGPVIPASAYLMK
MMAR_0065|M.marinum_M               DVPLNLEYKLEVWDSPNSAGIIIDAVRAAKIAKDRGIGGPVIPASAYLMK
Mflv_0867|M.gilvum_PYR-GCK          DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPIEAASAYLMK
Mvan_6040|M.vanbaalenii_PYR-1       DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPIEAASAYLMK
MSMEG_6904|M.smegmatis_MC2_155      DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPIEAASAYLMK
MAB_4907|M.abscessus_ATCC_1997      DVPLNLEYKLEVWDSPNSAGIIIDAVRAAKIALDRGLGGPILPASAYLMK
Mb0047c|M.bovis_AF2122/97           DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMK
Rv0046c|M.tuberculosis_H37Rv        DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMK
MLBr_02692|M.leprae_Br4923          DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASSYLMK
MAV_0067|M.avium_104                DVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMK
TH_1311|M.thermoresistible__bu      DVPLNLEYKLEVWDSPNSAGVIIDAIRAAKIAKDRGIGGPIESASAYLMK
                                    ********************:****:****** ***:***: .**:****

MUL_0064|M.ulcerans_Agy99           SPPKQLADDVARTQLEEFIIEG-
MMAR_0065|M.marinum_M               SPPKQLADDVARTQLEEFIIEG-
Mflv_0867|M.gilvum_PYR-GCK          SPPKQLADDIARVQLEKFIEG--
Mvan_6040|M.vanbaalenii_PYR-1       SPPKQLADDIARVQLEKFIEG--
MSMEG_6904|M.smegmatis_MC2_155      SPPKQLADDVARAELETFIEG--
MAB_4907|M.abscessus_ATCC_1997      SPPKQLADDVARAELEQFIAG--
Mb0047c|M.bovis_AF2122/97           SPPEQLPDDIARAQLEEFIIG--
Rv0046c|M.tuberculosis_H37Rv        SPPEQLPDDIARAQLEEFIIG--
MLBr_02692|M.leprae_Br4923          SPPQQLPDEIARAQLEEFIIDTK
MAV_0067|M.avium_104                SPPQQLPDDVARTQLEEFIIGG-
TH_1311|M.thermoresistible__bu      SPPTQMPDDIARAKLEEFIKG--
                                    *** *:.*::**.:** **