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MNRDRARSEATAGQRCGLWLSGARGSVATTSIVGLYALSAGLVSETGCVTSNADFADVPLPNYSDFVVGG RDLSTTSLAKRAETLVEAGLLPHQVVATLSDRLAATDDEIVGPSCVATPDPCSAGASTQAELIGLCDAMA SFVSRHGLDGLVVIDVASTQPPVADLPEYRDPQLLRLALGEKNRALLPASALTALAAIRTGAAYACFTPS PSLGIPALRQLAAEADISYAGQDAKTGQTLLRTVLAPMFASRAMNVHSWAGSNLLGGGDGATLADPVAVQ SKLASKQRGIQQMLGGHVTAPLHIDYVPDLGETKVAWDFIHATGFLGGQITLQTTWSAPDSALAAPLVLD VARLLSMARMRGAQGVVGELGFFFKEPWGSSTHSLAAQYEALHQWANSFSTPDSAEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1692 | - | - | 100% (407) | myo-inositol-1-phosphate synthase |
| M. ulcerans Agy99 | MUL_0064 | ino1 | 7e-08 | 24.88% (205) | myo-inositol-1-phosphate synthase Ino1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0047c | ino1 | 2e-07 | 25.37% (201) | myo-inositol-1-phosphate synthase INO1 (inositol 1-phosphate |
| M. gilvum PYR-GCK | Mflv_0867 | - | 3e-07 | 24.23% (194) | myo-inositol-1-phosphate synthase |
| M. tuberculosis H37Rv | Rv0046c | ino1 | 2e-07 | 25.37% (201) | myo-inositol-1-phosphate synthase INO1 (inositol 1-phosphate |
| M. leprae Br4923 | MLBr_02692 | - | 4e-08 | 25.51% (196) | hypothetical protein MLBr_02692 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2508 | - | 0.0 | 99.26% (408) | myo-inositol-1-phosphate synthase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_6040 | - | 4e-07 | 24.23% (194) | myo-inositol-1-phosphate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0047c|M.bovis_AF2122/97 MSEHQSLPAPEAST------------EVRVAIVGVGNCASSLVQGVEYYY
Rv0046c|M.tuberculosis_H37Rv MSEHQSLPAPEAST------------EVRVAIVGVGNCASSLVQGVEYYY
MLBr_02692|M.leprae_Br4923 MSEHNPAGAPGAST------------EVRVAIVGVGNCASSLVQGIEYYQ
Mflv_0867|M.gilvum_PYR-GCK ---------MTASN------------DVRVAIVGVGNCASSLVQGVQYYK
Mvan_6040|M.vanbaalenii_PYR-1 ---------MTASN------------DVRVAIVGVGNCASSLVQGVQYYK
MUL_1692|M.ulcerans_Agy99 MNRDRARSEATAGQRCGLWLSGARGSVATTSIVGLYALSAGLVSETGCVT
MMAR_2508|M.marinum_M MNRDRARSEATAGQRCGLWLSGARGSVATTSIVGLYALSAGLVSETGCVT
*. . .:***: ::.**.
Mb0047c|M.bovis_AF2122/97 NADDTSTVPGLMHVRFGP--------YHVRDVKFVAAFDVDAKKVGFDLS
Rv0046c|M.tuberculosis_H37Rv NADDTSTVPGLMHVRFGP--------YHVRDVKFVAAFDVDAKKVGFDLS
MLBr_02692|M.leprae_Br4923 NADDTSTVPGLMHVRFGP--------YHVRDVKFVAAFDVDAKKVGVDLS
Mflv_0867|M.gilvum_PYR-GCK DADENASVPGLMHVKLGA--------YHVRDVKFVAAFDVDAKKVGFDLS
Mvan_6040|M.vanbaalenii_PYR-1 DADENATVPGLMHVKLGP--------YHVRDVKFVAAFDVDAKKVGFDLS
MUL_1692|M.ulcerans_Agy99 SNADFADVPLPNYSDFVVGGRDLSTTSLAKRAETLVEAGLLPHQVVATLS
MMAR_2508|M.marinum_M SNADFADVPLPNYSDFVVGGRDLSTTSLVKRAETLVEAGLLPHQVVATLS
. : : ** : : .: .: :. .: .::* **
Mb0047c|M.bovis_AF2122/97 DAIFASENNTIKIADVAPTNVIVQ-RGPTLDGIGKYYADTIELSDAEPVD
Rv0046c|M.tuberculosis_H37Rv DAIFASENNTIKIADVAPTNVIVQ-RGPTLDGIGKYYADTIELSDAEPVD
MLBr_02692|M.leprae_Br4923 DAIFTSENNTIKIADVPPTNVVVQ-RGPTLDGIGKYYTDTIELSDVPPVD
Mflv_0867|M.gilvum_PYR-GCK EAIFASENNTIKIADVPPTDVVVQ-RGPTLDGIGKYYADTIEISDADAVD
Mvan_6040|M.vanbaalenii_PYR-1 EAIFASENNTIKIADVPPTDVVVQ-RGPTLDGIGKYYADTIEISDAEAVD
MUL_1692|M.ulcerans_Agy99 DRLAATDDEIVGPSCVATPDPCSAGASTQAELIG-LCDAMASFVSRHGLD
MMAR_2508|M.marinum_M DRLAATDDEIVGPSCVATPDPCSAGASTQAELIDRLCDAMASFVSRHGLD
: : ::::: : : *...: .. : *. .: . :*
Mb0047c|M.bovis_AF2122/97 VVQALKEAKVDVLVSYLPVGSEE----------------ADKFYAQCAID
Rv0046c|M.tuberculosis_H37Rv VVQALKEAKVDVLVSYLPVGSEE----------------ADKFYAQCAID
MLBr_02692|M.leprae_Br4923 VVQALTEAKTDVLVSYLPVGSEE----------------ADKFYAQCAIN
Mflv_0867|M.gilvum_PYR-GCK VVKVLKDAKVDVMVSYLPVGSEE----------------ADKFYAQCAID
Mvan_6040|M.vanbaalenii_PYR-1 VVKVLKDAKVDVLVSYLPVGSEE----------------ADKFYAQCAID
MUL_1692|M.ulcerans_Agy99 GLVVIDVASTQPPVADLPEYRDPQLLRLALGEKNRALLPASALTALAAIR
MMAR_2508|M.marinum_M GLVVIDVASTQPPVADLPEYRDPQLLRLALGEKNRALLPASALTALAAIR
: .: *..: *: ** : *. : * .**
Mb0047c|M.bovis_AF2122/97 AGVAFVNALPVFIASDPVWAKKFTDAGVPIVGDDIKSQVGATITHRVLAK
Rv0046c|M.tuberculosis_H37Rv AGVAFVNALPVFIASDPVWAKKFTDARVPIVGDDIKSQVGATITHRVLAK
MLBr_02692|M.leprae_Br4923 ARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKSQVGATITHRVMAK
Mflv_0867|M.gilvum_PYR-GCK AGVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKSQIGATITHRVMAK
Mvan_6040|M.vanbaalenii_PYR-1 AGVAFVNALPVFIASDPVWAKKFEDAGVPIVGDDIKSQIGATITHRVMAK
MUL_1692|M.ulcerans_Agy99 TGAAYACFTPSPSLGIPALRQLAAEADISYAGQDAK--TGQTLLRTVLAP
MMAR_2508|M.marinum_M TGAAYACFTPSPSLGIPALRQLAAEADISYAGQDAK--TGQTLLRTVLAP
: .*:. * . *. : :* :. .*:* * * *: : *:*
Mb0047c|M.bovis_AF2122/97 LFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLKR-
Rv0046c|M.tuberculosis_H37Rv LFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLKR-
MLBr_02692|M.leprae_Br4923 LFEDRGVQLDRTMQLNVGGNMDFLNMLERERVQSKKISKTQAVTSNVHR-
Mflv_0867|M.gilvum_PYR-GCK LFEDRGVTLDRTYQLNVGGNMDFLNMLERTRLESKKVSKTQAVTSNLSGS
Mvan_6040|M.vanbaalenii_PYR-1 LFEDRGVTLDRTYQLNVGGNMDFLNMLERSRLESKKVSKTQAVTSNLSGS
MUL_1692|M.ulcerans_Agy99 MFASRAMNVHSWAGSNLLGGGDGATLADPVAVQSKLASKQRGIQQMLGG-
MMAR_2508|M.marinum_M MFASRAMNVHSWAGSNLLGGGDGATLADPVAVQSKLASKQRGIQQMLGG-
:* .*.: :. *: *. * .: : ::** ** :.: . :
Mb0047c|M.bovis_AF2122/97 ---EFKTKDVHIGPSDHVGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVW
Rv0046c|M.tuberculosis_H37Rv ---EFKTKDVHIGPSDHVGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVW
MLBr_02692|M.leprae_Br4923 ---EFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPLNLEYKLEVW
Mflv_0867|M.gilvum_PYR-GCK LAGKVEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVW
Mvan_6040|M.vanbaalenii_PYR-1 LAGKIEDKNVHIGPSDHVAWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVW
MUL_1692|M.ulcerans_Agy99 ----HVTAPLHI---DYVPDLGETKVAWDFIHATGFLGGQITLQTTWSAP
MMAR_2508|M.marinum_M ----HVTAPLHI---DYVPDLGETKVAWDFIHATGFLGGQITLQTTWSAP
:** *:* *.: * *: :.. .* . :.*: . ..
Mb0047c|M.bovis_AF2122/97 DSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMKSPPEQLPDDIAR-
Rv0046c|M.tuberculosis_H37Rv DSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASAYLMKSPPEQLPDDIAR-
MLBr_02692|M.leprae_Br4923 DSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIAR-
Mflv_0867|M.gilvum_PYR-GCK DSPNSAGVIIDAVRAAKIAKDRGIGGPIEAASAYLMKSPPKQLADDIAR-
Mvan_6040|M.vanbaalenii_PYR-1 DSPNSAGVIIDAVRAAKIAKDRGIGGPIEAASAYLMKSPPKQLADDIAR-
MUL_1692|M.ulcerans_Agy99 DSALAAPLVLDVARLLSMARMRGAQG-VVGELGFFFKEPWGSSTHSLAAQ
MMAR_2508|M.marinum_M DSALAAPLVLDVARLLSMARMRGAQG-VVGELGFFFKEPWGSSTHSLAAQ
**. :* :::*..* .:*: ** * : .:::*.* . ...:*
Mb0047c|M.bovis_AF2122/97 -AQLEEFIIG---------
Rv0046c|M.tuberculosis_H37Rv -AQLEEFIIG---------
MLBr_02692|M.leprae_Br4923 -AQLEEFIIDTK-------
Mflv_0867|M.gilvum_PYR-GCK -VQLEKFIEG---------
Mvan_6040|M.vanbaalenii_PYR-1 -VQLEKFIEG---------
MUL_1692|M.ulcerans_Agy99 YEALHQWANSFSTPDSAEL
MMAR_2508|M.marinum_M YEALHQWANSFSTPDSAEL
*.:: .