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VATTALRGLHVLETLAGMRQPATLRDVAARAGLSESNAFRILQALENEGYVHHLGRSGYRLASRALALAT VIGPRPAMLRLMHPIVARLAAVSGEAAVVHLRAGQFRVLVLGVPAPSGPIVDPAGVLGERSPLAAGASGR IILAYLTETELADVDLDGVTPEQLAEIRDRGYETSYGENHPGINGISVPLLATPDDPGAALIVLGSMTIA GPAERLPPRAVTRLVGPLLGACRDLSPRLAALLGPNPGATIDALDL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6857 | - | - | 100% (256) | putative transcription regulator |
| M. smegmatis MC2 155 | MSMEG_2386 | - | 1e-17 | 28.63% (234) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2507 | - | 2e-15 | 28.03% (239) | IclR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3013 | - | 2e-15 | 28.93% (242) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4228 | - | 2e-16 | 30.08% (236) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv2989 | - | 3e-15 | 28.93% (242) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3295 | - | 1e-14 | 25.00% (220) | IclR family transcriptional regulator |
| M. marinum M | MMAR_1725 | - | 1e-17 | 30.74% (244) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 2e-15 | 29.49% (234) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_2042 | - | 2e-16 | 27.78% (234) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1967 | - | 4e-18 | 30.74% (244) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2134 | - | 6e-16 | 28.21% (234) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3013|M.bovis_AF2122/97 MRQHSGIGVLDKAVGVLHAVAESPCGLAELCDRTDLPRATAYRLAAALEV
Rv2989|M.tuberculosis_H37Rv MRQHSGIGVLDKAVGVLHAVAESPCGLAELCDRTDLPRATAYRLAAALEV
MAV_3839|M.avium_104 -------------MGVLHTVAQSPCGLAELCERTELPRATAYRLAAALEV
MMAR_1725|M.marinum_M MRQDSGIGVIDKAVGLLRATAESPCGLAELCERTGLPRATAYRLAAALEV
MUL_1967|M.ulcerans_Agy99 MRQDSGIGVIDKAVGLLRATAKSPCGLAELCERTGLPRATAYRLAAALEV
Mflv_4228|M.gilvum_PYR-GCK MRQNSGIGVLDKAITVLHAVAESPCGLADLCERTDLPRATAHRLAVGLEV
Mvan_2134|M.vanbaalenii_PYR-1 MRQNSGIGVLDKAVTVLHAVAESPCGLADLCERTNLPRATAHRLAVGLEV
TH_2042|M.thermoresistible__bu MRKDSGIGVLDKAVSVLHSVAESPCGLAELCERTGLPRATAHRLAAGLEV
MAB_3295|M.abscessus_ATCC_1997 MRQHSGIGVLDKAVQVLTAIGDSPCGLAELCERTGLPRATAHRLAAGLEV
MSMEG_6857|M.smegmatis_MC2_155 ---MATTALRGLHVLETLAGMRQPATLRDVAARAGLSESNAFRILQALEN
: : .*. * ::. *: *..:.*.*: .**
Mb3013|M.bovis_AF2122/97 HRLLGRGQDGHWRLGPAITELATHVD--DPLLVACAAVLPQLRDATGESV
Rv2989|M.tuberculosis_H37Rv HRLLGRGQDGHWRLGPAITELATHVD--DPLLVACAAVLPQLRDATGESV
MAV_3839|M.avium_104 HRLLARGDDGRWRLGPAVTELAAHVN--DPLLAAGSAVLPLLRETTGESV
MMAR_1725|M.marinum_M HRLLGRDEDGRWGLGPAITELAAHVD--DPLLTAGATVLPRLRETTGESV
MUL_1967|M.ulcerans_Agy99 HRLLGRDEDGRWGLGPAITELAAHVD--DPLLTAGATVLPRLCETTGESV
Mflv_4228|M.gilvum_PYR-GCK HRLLARDGDGLWRLGPALTELAGHVN--DSLLAAGAVVLPRLRELTGESV
Mvan_2134|M.vanbaalenii_PYR-1 HRLLAREGDGQWRLGPALTELAGHVN--DPLLAAGAVVLPRLRELTGESV
TH_2042|M.thermoresistible__bu HRLLARDGDGRWCLGPAVTELAARVD--DPLLAAAAVVLPRLREITGESV
MAB_3295|M.abscessus_ATCC_1997 HRLLSRDGDGQWQLGAGLTELAAHVN--DPLLSASAQVLPKLREITGESV
MSMEG_6857|M.smegmatis_MC2_155 EGYVHHLGRSGYRLASRALALATVIGPRPAMLRLMHPIVARLAAVSGEAA
. : : . : *.. ** :. .:* ::. * :**:.
Mb3013|M.bovis_AF2122/97 QVYRREGTSRVCVAALEPAAG--LRDTVPVGARLPMTAGSGAKVLLAHTD
Rv2989|M.tuberculosis_H37Rv QVYRREGTSRVCVAALEPAAG--LRDTVPVGARLPMTAGSGAKVLLAHTD
MAV_3839|M.avium_104 QLYRREGTDRVCVAALEPAAG--LRDTVPVGARLPMTAGSGAKVLLAHSD
MMAR_1725|M.marinum_M QLYRREGTSRVCVAALEPPAG--LRDTVPVGARLPMTAGSGAKVLLAHSD
MUL_1967|M.ulcerans_Agy99 QLYRREGTSRVCVAALEPPAG--LRDTVPVGARLPMTAGSGAKVLLAHSD
Mflv_4228|M.gilvum_PYR-GCK QLYRREGTSRICVAALEPPAG--LRDTVPVGTRLSMTAGSGAKVLLAYAD
Mvan_2134|M.vanbaalenii_PYR-1 QLYRREGTTRICIAALEPPAG--LRDTVPVGIRLPMTAGSGAKVLLAYAD
TH_2042|M.thermoresistible__bu QLYRREGTSRICVAALEPPAG--LRDTVPVGTRLPMTAGSGAKVLLAYAD
MAB_3295|M.abscessus_ATCC_1997 QLYRREGTVRICVAALEPPAG--LRDTVPVGSRLPMSAGSGAKVLLAHSD
MSMEG_6857|M.smegmatis_MC2_155 VVHLRAGQFRVLVLGVPAPSGPIVDPAGVLGERSPLAAGASGRIILAYLT
:: * * *: : .: ..:* : : :* * .::**:..:::**:
Mb3013|M.bovis_AF2122/97 AATQAAVLPKAVFSARALAEVCRRGWAQSVAEREPGVASVSAPVRDGRG-
Rv2989|M.tuberculosis_H37Rv AATQAAVLPKAVFSARALAEVCRRGWAQSVAEREPGVASVSAPVRDGRG-
MAV_3839|M.avium_104 AATQKAVLANAKFTERTLAEVRRRGWAQSVAEREPGVASVSAPVRDSRG-
MMAR_1725|M.marinum_M PATQQAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRG-
MUL_1967|M.ulcerans_Agy99 PATQQAVLPTAKFTDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRG-
Mflv_4228|M.gilvum_PYR-GCK THTQQAVLPNAKFTDRTLAEVRKRGWAQSAAEREPGVASVSAPVRDGRG-
Mvan_2134|M.vanbaalenii_PYR-1 AATQQAVLPGAKFTDRTLAEVRRRGWAQSAAEREPGVASVSAPVRDGRG-
TH_2042|M.thermoresistible__bu STTQQAVLSNAKFSERALAEVHKRGWAQSVAEREPGVASVSAPVRDGRG-
MAB_3295|M.abscessus_ATCC_1997 PGTQAAVLPGATFTERALADVRKRGWAQSAAEREAGVASVSAPVRDRHG-
MSMEG_6857|M.smegmatis_MC2_155 -ETELADVDLDGVTPEQLAEIRDRGYETSYGENHPGINGISVPLLATPDD
*: * : .: . **:: **: * .*...*: .:*.*: .
Mb3013|M.bovis_AF2122/97 -----VVIAAISVSGPIDRMGRRPGVRWAADLLSAADALTRRL-------
Rv2989|M.tuberculosis_H37Rv -----VVIAAISVSGPIDRMGRRPGVRWAADLLSAADALTRRL-------
MAV_3839|M.avium_104 -----AVIAAISVSGPIDRIGRRPGARWAADLVSAAEALTRRL-------
MMAR_1725|M.marinum_M -----VVVAAISVSGPIDRIGRRPGARWAADLLAAADELARRL-------
MUL_1967|M.ulcerans_Agy99 -----VVVAAISVSGPIDRIGRRPGARWAADLLAAADELARRL-------
Mflv_4228|M.gilvum_PYR-GCK -----AVIAAVSVSGPIDRMGRRPGARWAADLVAAADALTRRL-------
Mvan_2134|M.vanbaalenii_PYR-1 -----AVVAAVSVSGPIDRMGRRPGARWAADLVAAADALTRRL-------
TH_2042|M.thermoresistible__bu -----TVVAAVSVSGPIDRIGRRPGARWAADLLAAAEALTRRL-------
MAB_3295|M.abscessus_ATCC_1997 -----NVIAAISVSGPIDRMGRRPGARWAADLVAASEAITARL-------
MSMEG_6857|M.smegmatis_MC2_155 PGAALIVLGSMTIAGPAERLPPRAVTRLVGPLLGACRDLSPRLAALLGPN
*:.:::::** :*: *. .* .. *:.*. :: **
Mb3013|M.bovis_AF2122/97 ----------
Rv2989|M.tuberculosis_H37Rv ----------
MAV_3839|M.avium_104 ----------
MMAR_1725|M.marinum_M ----------
MUL_1967|M.ulcerans_Agy99 ----------
Mflv_4228|M.gilvum_PYR-GCK ----------
Mvan_2134|M.vanbaalenii_PYR-1 ----------
TH_2042|M.thermoresistible__bu ----------
MAB_3295|M.abscessus_ATCC_1997 ----------
MSMEG_6857|M.smegmatis_MC2_155 PGATIDALDL