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SIDPIAVGILIGGFAVLILLRIPIALALALAAVFEAFYLDLPLPIVGQRMVAGLDIFALLAIPFFILGGE IMAAGGISRRLIAFASLFVGWLRGGLAMINIGSSTFFGALSGSSVADVSAIGSATIPMMKQKGYDADYAV CVTITGAAQAVMIPPSHNLVIFSMAAGGVSIGALFVAGIVPGLLIGLSLLVLAYLLAVRRGYPKETLVPV SEVPRIVWEGLLSLLMPVIILGGILSGIFTATESAAIGCVYAFFLTFFVYRDIPLSGFIPILQRTARTLG IVLFIIAAAGAFGYFLTFLQVPEAVTQALLGLSDNKIVILLVINLLLLALGAVMDMAPLILIMTPILLPV ATSIGMDPVQFGIMLLLNLAIGLITPPVGNVLFVGAAIGQISIEKVSRALPVFLVPMLLVLLLITFLPQL SLALPGLLGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6845 | - | - | 100% (431) | trap dicarboxylate transporter, dctm subunit |
| M. smegmatis MC2 155 | MSMEG_3350 | - | 7e-35 | 27.56% (439) | TRAP transporter, DctM-like membrane protein |
| M. smegmatis MC2 155 | MSMEG_0984 | - | 4e-14 | 23.36% (458) | trap transporter, 4tm/12tm fusion protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 3e-05 | 25.19% (401) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_4420 | - | 1e-11 | 23.54% (378) | TRAP transporter, 4TM/12TM fusion protein |
| M. tuberculosis H37Rv | Rv1258c | - | 3e-05 | 25.19% (401) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0726 | - | 9e-05 | 32.11% (109) | hypothetical protein MAV_0726 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1934 | - | 1e-12 | 22.63% (380) | TRAP transporter, 4TM/12TM fusion protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4420|M.gilvum_PYR-GCK MDRTTAS----------TVESTALGQVDDQDKPGRELRGWTYGLVAVVAF
Mvan_1934|M.vanbaalenii_PYR-1 MDRSSAEEPGGPPTVVATAEPPAVPQVDDQEKPARELRGWTQRFVAGVAF
Mb1288c|M.bovis_AF2122/97 --------------------------------------------------
Rv1258c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0726|M.avium_104 --------------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4420|M.gilvum_PYR-GCK AVAVLTIWQVFRPLSQGSQYYLIVFLSGTLPLVYLVYRSGWRWS-DPEDR
Mvan_1934|M.vanbaalenii_PYR-1 GVAILTIWQVFRPLSQGSQYYLIVFLAGSLPLVFLAYRSGIRSSRSSQQE
Mb1288c|M.bovis_AF2122/97 ----------MRNSNRGP-AFLILFAT-----------------------
Rv1258c|M.tuberculosis_H37Rv ----------MRNSNRGP-AFLILFAT-----------------------
MAV_0726|M.avium_104 --------------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 ----MSIDPIAVGILIGGFAVLILLRIP----------------------
Mflv_4420|M.gilvum_PYR-GCK PGVLDWALAFVAVLVCLYPVLAPAIGAAGGGYNAFLDRQGMLDPLDVVMG
Mvan_1934|M.vanbaalenii_PYR-1 PGALDWSLALVTLLVCLYPILPVRIGAGGGGYNAFLDRQGMLEPIDVAMG
Mb1288c|M.bovis_AF2122/97 --LMAAAGDGVSIVAFPWLVLQ---------------REGSAGQASIVAS
Rv1258c|M.tuberculosis_H37Rv --LMAAAGDGVSIVAFPWLVLQ---------------REGSAGQASIVAS
MAV_0726|M.avium_104 ---------------------------------------MSVSRLWEVGM
MSMEG_6845|M.smegmatis_MC2_155 ---IALALALAAVFEAFYLDLPLPIVG-----------QRMVAGLDIFAL
Mflv_4420|M.gilvum_PYR-GCK ALLLVLIIEACRRTTGWALPIVCAAFLVYGYYGGLMPQGWAIAHAGLDFD
Mvan_1934|M.vanbaalenii_PYR-1 ALLLVLILEACRRTTGWALPVVCAMFLAYGYYGGLMPQGWAIAHAGLDFD
Mb1288c|M.bovis_AF2122/97 ATMLPLLFATLVAGT------------AVDYFG------------RRRVS
Rv1258c|M.tuberculosis_H37Rv ATMLPLLFATLVAGT------------AVDYFG------------RRRVS
MAV_0726|M.avium_104 APLITLVVG----------------------------------------S
MSMEG_6845|M.smegmatis_MC2_155 LAIPFFILGG--------------------------------------EI
: ::.
Mflv_4420|M.gilvum_PYR-GCK QIVDALYNSGSGFFGTPLDVAATYIVLFTIYGAVLELSGGARFFVNLSVA
Mvan_1934|M.vanbaalenii_PYR-1 QIIDALYNSGSGFFGTPLDVAATYIVLFTIYGAVLELSGGARFFVDLSVA
Mb1288c|M.bovis_AF2122/97 MVADALS--GAAVAGVPLVAWG----------------------------
Rv1258c|M.tuberculosis_H37Rv MVADALS--GAAVAGVPLVAWG----------------------------
MAV_0726|M.avium_104 LVAWVVGRLGVAYVDG----------------------------------
MSMEG_6845|M.smegmatis_MC2_155 MAAGGISRRLIAFASLFVGWLR----------------------------
: . .
Mflv_4420|M.gilvum_PYR-GCK AFRRSRSAAGRTAVASGFLLGTVSGSGTATAVSVGAVTWPIMRRAGYTPE
Mvan_1934|M.vanbaalenii_PYR-1 AFRRSRSAAGRTTVASGFLLGTVSGSGTATAVSVGAITWPIMRRAGYTPE
Mb1288c|M.bovis_AF2122/97 -----YGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLD
Rv1258c|M.tuberculosis_H37Rv -----YGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLD
MAV_0726|M.avium_104 -----WAPALAVGLAAMFVLTGIAHFAPPLRADLVVIVPPRLPAPGLLVS
MSMEG_6845|M.smegmatis_MC2_155 ------GGLAMINIGSSTFFGALSGSSVADVSAIGSATIPMMKQKGYDAD
. : . : . . * .
Mflv_4420|M.gilvum_PYR-GCK RAGGVLAAAGVGALLSPPTLGAAAFIVAEY---LEVSYLTVLGWAMIPTG
Mvan_1934|M.vanbaalenii_PYR-1 RAGGVLAAAGVGALLSPPTLGAAAFIVAEY---LEVSYLTVLGWAMIPTV
Mb1288c|M.bovis_AF2122/97 RINGAYEAILNLAFIVGPAIGGLMIATVGG---ITTMWITATAFGLS---
Rv1258c|M.tuberculosis_H37Rv RINGAYEAILNLAFIVGPAIGGLMIATVGG---ITTMWITATAFGLS---
MAV_0726|M.avium_104 -LTGVLELLGALGLLLPATRAAAAGCLLVL---MLAMFP-----------
MSMEG_6845|M.smegmatis_MC2_155 YAVCVTITGAAQAVMIPPSHNLVIFSMAAGGVSIGALFVAGIVPGLLIG-
. ..: .: : . :
Mflv_4420|M.gilvum_PYR-GCK LYYLGILLAVEIDARRFGMKAANLDAESPWKLLGRFGYHFSSLIAIVVLL
Mvan_1934|M.vanbaalenii_PYR-1 LYYLGILLAVEIDARRFGMKPAHQQSESPWKLLARFGYHFSSLVAIVVLL
Mb1288c|M.bovis_AF2122/97 --------ILAIAALQLEGAGKPHHTSRPQGLVS----------------
Rv1258c|M.tuberculosis_H37Rv --------ILAIAALQLEGAGKPHHTSRPQGLVS----------------
MAV_0726|M.avium_104 ---------ANIHASRMPDPPKSMTTRLP---------------------
MSMEG_6845|M.smegmatis_MC2_155 ------LSLLVLAYLLAVRRGYPKETLVPVSEVP----------------
: : *
Mflv_4420|M.gilvum_PYR-GCK AVGMSATRAVIFATALAFVLSFADRRFRLTPRRLFGALSSGVLGVLPVVA
Mvan_1934|M.vanbaalenii_PYR-1 AAGMSATRAVVYATALAFVLSFLDRWGRLTPRRLFDALSVGVRGVLPVVA
Mb1288c|M.bovis_AF2122/97 ----------GIAEGLRFVWN-------LRVLRTLGMIDLTVTALYLPME
Rv1258c|M.tuberculosis_H37Rv ----------GIAEGLRFVWN-------LRVLRTLGMIDLTVTALYLPME
MAV_0726|M.avium_104 -------------------------------------LRIGMEIVFLAAA
MSMEG_6845|M.smegmatis_MC2_155 ----------------RIVWEG-----LLSLLMPVIILGGILSGIFTATE
: : :
Mflv_4420|M.gilvum_PYR-GCK VCAAAGVITAMTTKTGLGAQFSSVLVGGVDAITDNRTVMLALTAVFAAVA
Mvan_1934|M.vanbaalenii_PYR-1 VCAAAGVITAMTTKTGLGAQFSSVLVGGVDALTDNRTLMLALTAVFAAVA
Mb1288c|M.bovis_AF2122/97 SVLFPKYFTDHQQPVQLGWALMAIAGG----------------GLVGALG
Rv1258c|M.tuberculosis_H37Rv SVLFPKYFTDHQQPVQLGWALMAIAGG----------------GLVGALG
MAV_0726|M.avium_104 VAVALGGR------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 SAAIGCVYAFFLTFFVYRDIPLSGFIPILQRTARTLGIVLFIIAAAGAFG
Mflv_4420|M.gilvum_PYR-GCK LALLGLAIPVTASFVIGWVIIGPALLALDVPAPAAAMFVFYYSVLSEVTP
Mvan_1934|M.vanbaalenii_PYR-1 LALLGLAIPVTASFVIGWVIIGPALLALDVPAPAAAMFVFYYSVLSEVTP
Mb1288c|M.bovis_AF2122/97 YAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGP
Rv1258c|M.tuberculosis_H37Rv YAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGP
MAV_0726|M.avium_104 --------------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 YFLTFLQVPEAVTQALLGLSDNKIVILLVINLLLLALGAVMDMAPLILIM
Mflv_4420|M.gilvum_PYR-GCK PTALAAVGASAVTGGQAIPTMWQALRYAAPAFLVPIAFVLTGPGEYLLAR
Mvan_1934|M.vanbaalenii_PYR-1 PTALAAVGASAVTGGRAIPTMWQALRYAAPAFLVPIAFVLTAPGEYLLGR
Mb1288c|M.bovis_AF2122/97 IQPIYNYVIQTRAA--------QHLRGRVVGVMTSLAYAAGPLG--LLLA
Rv1258c|M.tuberculosis_H37Rv IQPIYNYVIQTRAA--------QHLRGRVVGVMTSLAYAAGPLG--LLLA
MAV_0726|M.avium_104 --------------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 TPILLPVATSIGMD--------PVQFGIMLLLNLAIGLITPPVGNVLFVG
Mflv_4420|M.gilvum_PYR-GCK GPVLGVLWASAAACVGIVALSFAAGGWVLGVGAMGPPARVLTAVAALLLL
Mvan_1934|M.vanbaalenii_PYR-1 GPVLGVIWASVAACAGIVALSFAAGGWVLGVGALAPVPRAFTAIAALLLL
Mb1288c|M.bovis_AF2122/97 GPLT--------DAAGLHATFLALA---LPIVCTGLVAIRLPALRELDLA
Rv1258c|M.tuberculosis_H37Rv GPLT--------DAAGLHATFLALA---LPIVCTGLVAIRLPALRELDLA
MAV_0726|M.avium_104 --------------------------------------------------
MSMEG_6845|M.smegmatis_MC2_155 ------------AAIGQISIEKVSRALPVFLVPMLLVLLLITFLPQLSLA
Mflv_4420|M.gilvum_PYR-GCK YLHPVSIAAGFTCLLCAVAFTFITDKRRRP
Mvan_1934|M.vanbaalenii_PYR-1 FLQPATIAAGSACLLGAVAFTFITDKRRRT
Mb1288c|M.bovis_AF2122/97 PQADIDRPVGSAQ-----------------
Rv1258c|M.tuberculosis_H37Rv PQADIDRPVGSAQ-----------------
MAV_0726|M.avium_104 ------------------------------
MSMEG_6845|M.smegmatis_MC2_155 LPGLLGL-----------------------