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CPDWREREAFCSGPGELLDALIDHWEQHGDRDRLHYERFQPKIGGDAGAGNGGTVTFLDSETTAECGGGT PILEAGEQAGLKLAYGCRIGICHTCTGTVRSGKVRDLRSGEIAEPTGQDVRICINAAEGDVEIEL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6836 | - | - | 100% (136) | putative oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_1885 | - | 1e-22 | 37.31% (134) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1742 | - | 2e-18 | 37.31% (134) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3259c | - | 4e-27 | 43.28% (134) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_5247 | - | 3e-67 | 83.21% (137) | ferredoxin |
| M. tuberculosis H37Rv | Rv3230c | - | 4e-27 | 43.28% (134) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3549c | - | 2e-23 | 38.81% (134) | putative oxidoreductase |
| M. marinum M | MMAR_1314 | - | 4e-27 | 42.54% (134) | oxidoreductase |
| M. avium 104 | MAV_4193 | - | 3e-25 | 41.04% (134) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. thermoresistible (build 8) | TH_2872 | - | 5e-25 | 41.35% (133) | PUTATIVE 2Fe-2S iron-sulfur cluster binding domain protein |
| M. ulcerans Agy99 | MUL_2566 | - | 2e-27 | 42.54% (134) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1767 | - | 6e-27 | 43.38% (136) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2872|M.thermoresistible__bu ----MAKSEIKYSARVVDTVRPQVAGVENRPVLHRLRRFAERITTPLLPD
Mvan_1767|M.vanbaalenii_PYR-1 ----MAKNTIKNTAKVADTVRPTIAGAKENPGWHLLRTIAGRITTPLLPD
Mb3259c|M.bovis_AF2122/97 ----MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPD
Rv3230c|M.tuberculosis_H37Rv ----MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPD
MMAR_1314|M.marinum_M ----MVKKNAALSAQIIDTKRPNIVGADKHPGWHALRKIASRITTPLLPD
MUL_2566|M.ulcerans_Agy99 ----MVKKNAALSAQIIDTKRPSIVGADKHPGWHALRKIASRITTPLLPD
MAV_4193|M.avium_104 MSNTMSKTTSPITANLGDTKRPVVAGAERHPGWHALRKLAARITTPLLPD
MAB_3549c|M.abscessus_ATCC_199 ----------MKLASWLDASAPGAP-KSRHAAVNILRGLASRITTPLLPD
MSMEG_6836|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5247|M.gilvum_PYR-GCK -------------------MAERGAQPPVPRGRRLFLKAVHHLFKPLRPD
TH_2872|M.thermoresistible__bu DYLHLINPLWSARELRGRVEDVRRETEDSATLVIKPGWGFSFDYQPGQYI
Mvan_1767|M.vanbaalenii_PYR-1 DYLKLANPLWSARELRGRVLEVRRETEDSATLVIKPGWGFSFDYEPGQYI
Mb3259c|M.bovis_AF2122/97 DYLHLANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYI
Rv3230c|M.tuberculosis_H37Rv DYLHLANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYI
MMAR_1314|M.marinum_M DYLQLANPLWSARELRGRILEVRRETEDSATLVIKPGWGFSFDYQPGQYI
MUL_2566|M.ulcerans_Agy99 DYLQLANPLWSARELRGRILEVRRETEDSATLVIKPGWGFSFDYQPGQYI
MAV_4193|M.avium_104 DYLHLANPLWSARELRGRVVDVRRETEDSATLVIKPGWGFNFDYQPGQYI
MAB_3549c|M.abscessus_ATCC_199 DYLSLANPLWSARELRGRVVSVRKETSDSATLEIKPGWGFHFDYHPGQYV
MSMEG_6836|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5247|M.gilvum_PYR-GCK DYIEMINPLWTTKELRGKVERVEPRGSEAASVLIRPSYEWPG-HKPGQYV
TH_2872|M.thermoresistible__bu GIGLPVDGRWRWRSYSLTSPAVTSG-----------RGGRTITITVKAMP
Mvan_1767|M.vanbaalenii_PYR-1 GIGLLVEGRWRWRSYSLTSSPVTS------------KGSRTITITVKAMP
Mb3259c|M.bovis_AF2122/97 GIGLLVDGCWRWRSYSLTSSPAAS------------GSARMVTVTVKAMP
Rv3230c|M.tuberculosis_H37Rv GIGLLVDGRWRWRSYSLTSSPAAS------------GSARMVTVTVKAMP
MMAR_1314|M.marinum_M GIGLLVDGRWRWRSYSLTSSPVGGKS--------GPGSARTVTITVKAMP
MUL_2566|M.ulcerans_Agy99 GIGLLVDGRWRWRSYSLTSSPVGGKS--------GPGSARTVTITVKAMP
MAV_4193|M.avium_104 GIGLLIDGRWRWRSYSLTSSPATS------------ASARTVTITVKAMP
MAB_3549c|M.abscessus_ATCC_199 GIGVLIDGRWRWRSYSLTSAPAMSGSREERRALHAGGSARTITITVKAMP
MSMEG_6836|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5247|M.gilvum_PYR-GCK RLGLVIDGRYHWRAYSLTSDPHPE--------------DGLISVTPKKVD
TH_2872|M.thermoresistible__bu EGFLSTHLVEGVKPGTIVRLAAPQGNFVMPNPAPPQVLFLTAGSGITPIM
Mvan_1767|M.vanbaalenii_PYR-1 EGFLSTHLVGGVAPGTIVRLAAPQGNFVMPDPAPASVLFLTAGSGITPVM
Mb3259c|M.bovis_AF2122/97 EGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVM
Rv3230c|M.tuberculosis_H37Rv EGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVM
MMAR_1314|M.marinum_M EGFLSTHLVAGVAPGTIVRLVAPQGNFVLPDPAPPSMLFLTAGSGITPVM
MUL_2566|M.ulcerans_Agy99 EGFLSTHLVAGVAPGTIVRLVAPQGNFVLPDPAPPSILFLTAGSGITPVM
MAV_4193|M.avium_104 EGFLSSHLVAGVEPGTVVRLAAPQGNFVLPDPAPASILFLTAGSGITPVM
MAB_3549c|M.abscessus_ATCC_199 EGFLSTHLVNGLEPGTIVRLAAPQGNFVLDDPAPPAILFLTAGSGITPIM
MSMEG_6836|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5247|M.gilvum_PYR-GCK SGVVSPYLVEKIQPGELVRLGEIEGQFTLPEPLPAKMLFISAGSGITPII
TH_2872|M.thermoresistible__bu SMLRTLERRDQIT-----DIVHIHSVPTPSDAMFSGELADLQRRHPSYRF
Mvan_1767|M.vanbaalenii_PYR-1 SMLRTLVRRGQLG-----DVAHVHSSPTEDDVMFAAELSELADRHEGYRL
Mb3259c|M.bovis_AF2122/97 SMLRTLVRRNQIT-----DVVHLHSAPTAADVMFGAELAALAADHPGYRL
Rv3230c|M.tuberculosis_H37Rv SMLRTLVRRNQIT-----DVVHLHSAPTAADVMFGAELAALAADHPGYRL
MMAR_1314|M.marinum_M SMLRTLLRRNQIT-----DITHLHSVPTEADVMFGDELAGVAAQHPGYRL
MUL_2566|M.ulcerans_Agy99 SMLRTLLRRNQIT-----DITHLHSVPTEADVMFGDELAGVAAQHPGYRL
MAV_4193|M.avium_104 SMLRTLVRRNQIG-----DIVHLHSAPTEADVMFRGELAALANEHPGYRL
MAB_3549c|M.abscessus_ATCC_199 SMLRTLVRRSAAAGLPLPDVVHLHSAPTAGDVMFAGELAAFSEAHPSYHY
MSMEG_6836|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5247|M.gilvum_PYR-GCK SMLRSLDHSDDLR-----DTVVIHSDRTRDHVMFLSVLEDLEDRHDGVRL
TH_2872|M.thermoresistible__bu RLRTTRTEGRLDLSRLDDEVGDWRSRQTWACGPEGLLTAAERVWLGAGIG
Mvan_1767|M.vanbaalenii_PYR-1 RVRATRTEGRLDLDRLDEVVPDWRERQTWACGPEAMLEAAERTWKAAGIA
Mb3259c|M.bovis_AF2122/97 SVRETRAQGRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGAS
Rv3230c|M.tuberculosis_H37Rv SVRETRAQGRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGAS
MMAR_1314|M.marinum_M SVRATRSQGRLDLSRIGEQVPDWRERQTWACGPESMLNQAEKVWSAAGIG
MUL_2566|M.ulcerans_Agy99 SVRATRSQGRLDLSRIGEQVPDWRERQTWACGPESMLNQAEKVWSAAGIG
MAV_4193|M.avium_104 QLRETRTRGRLDLSLLDREVPDWRERQTWACGPEGMLNAAERVWSAAGIG
MAB_3549c|M.abscessus_ATCC_199 RLRTTKTQGRLDFSSLAAEVPDWARRQTWACGPEGMLDDAQRTWADAGLA
MSMEG_6836|M.smegmatis_MC2_155 ------------------MCPDWREREAFCSGPGELLDALIDHWEQHGDR
Mflv_5247|M.gilvum_PYR-GCK DIRLTSERGRFSADELDDVCPDWREREAFCSGPGELLDALIEHWEHHGDS
** *:::..** :* * *
TH_2872|M.thermoresistible__bu DRLHLERFA---VARVANPGGGGTIEFARSGKSTVVDAATSLMDAGEQAG
Mvan_1767|M.vanbaalenii_PYR-1 DRLHLERFA---VARAAH-GSGGTVEFSRSGKAATVDGATSLMDAGEAAG
Mb3259c|M.bovis_AF2122/97 DRLHLERFA---VSKTAPAGAGGTVTFARSGKSVAADAATSLMDAGEGAG
Rv3230c|M.tuberculosis_H37Rv DRLHLERFA---VSKTAPAGAGGTVTFARSGKSVAADAATSLMDAGEGAG
MMAR_1314|M.marinum_M DRLHLERFA---VSKAAPAGAGGTVTFARSGRSVDVDAATSVMDAGERAG
MUL_2566|M.ulcerans_Agy99 DRLHLERFA---VSKAAPAGAGGTVTFARSGRSVDVDAATSVMDAGERAG
MAV_4193|M.avium_104 EQLHLERFA---VSKAAPAGAGGMVTFARSGRSVDADAATSLMDAGEAAG
MAB_3549c|M.abscessus_ATCC_199 ELLHLERFA---VSRAAPHGQGGLVTFARSGKQRAADAATSLMEAGEEAG
MSMEG_6836|M.smegmatis_MC2_155 DRLHYERFQPKIGG-DAGAGNGGTVTFLDSETTAECGGGTPILEAGEQAG
Mflv_5247|M.gilvum_PYR-GCK ERLHYERFQPKIGGGEVQAGEGGTVAFLDSDETVECDGSTPILEAGEQAG
: ** *** . . * ** : * * ...*.:::*** **
TH_2872|M.thermoresistible__bu VQMPFGCRMGICQSCVIGLVDGHVRDLRTGEVHDP-GTRVQTCVSAAAGD
Mvan_1767|M.vanbaalenii_PYR-1 IQMPFGCRMGICQSCVVGLLDGHVRDLRTGVEHEP-GTRVQTCVSAASGD
Mb3259c|M.bovis_AF2122/97 VQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEP-GTRVQTCVSAASGD
Rv3230c|M.tuberculosis_H37Rv VQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEP-GTRVQTCVSAASGD
MMAR_1314|M.marinum_M VQMPFGCRMGICQSCVVDLVQGHVRDLRTGQEHDP-GSRVQTCVTAASGD
MUL_2566|M.ulcerans_Agy99 VQMPFGCRMGICQSCVVDLVQGHVRDLRTGQEHDP-GSRVQTCVTAASGD
MAV_4193|M.avium_104 VQMPFGCRMGICQSCVVGLVEGHVRDLRTGAEHEP-GTRVQTCVSAASGD
MAB_3549c|M.abscessus_ATCC_199 VQMPFGCRMGICQTCVVSLVQGHARDLRTGAEYEP-GTRIQTCVSAASGD
MSMEG_6836|M.smegmatis_MC2_155 LKLAYGCRIGICHTCTGTVRSGKVRDLRSGEIAEPTGQDVRICINAAEGD
Mflv_5247|M.gilvum_PYR-GCK LELAFGCRIGICHTCTGTVKSGKVRDLRSGEVSEPTGGDIRICIHAAEGD
:::.:***:***::*. : .*:.****:* :* * :: *: ** **
TH_2872|M.thermoresistible__bu CVLDI
Mvan_1767|M.vanbaalenii_PYR-1 CVLDV
Mb3259c|M.bovis_AF2122/97 CVLDI
Rv3230c|M.tuberculosis_H37Rv CVLDI
MMAR_1314|M.marinum_M CVIDV
MUL_2566|M.ulcerans_Agy99 CAIDV
MAV_4193|M.avium_104 CVLDI
MAB_3549c|M.abscessus_ATCC_199 CVLDV
MSMEG_6836|M.smegmatis_MC2_155 VEIEL
Mflv_5247|M.gilvum_PYR-GCK VEIEL
:::