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M. avium 104 MAV_4193 (-)

annotation: 2Fe-2S iron-sulfur cluster binding domain-containing protein
coordinates: 4320597 - 4321751
length: 384

SNTMSKTTSPITANLGDTKRPVVAGAERHPGWHALRKLAARITTPLLPDDYLHLANPLWSARELRGRVVD
VRRETEDSATLVIKPGWGFNFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPATSASARTVTITVKAMPEGF
LSSHLVAGVEPGTVVRLAAPQGNFVLPDPAPASILFLTAGSGITPVMSMLRTLVRRNQIGDIVHLHSAPT
EADVMFRGELAALANEHPGYRLQLRETRTRGRLDLSLLDREVPDWRERQTWACGPEGMLNAAERVWSAAG
IGEQLHLERFAVSKAAPAGAGGMVTFARSGRSVDADAATSLMDAGEAAGVQMPFGCRMGICQSCVVGLVE
GHVRDLRTGAEHEPGTRVQTCVSAASGDCVLDI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4193--100% (384)2Fe-2S iron-sulfur cluster binding domain-containing protein
M. avium 104MAV_5168-3e-5039.09% (353) oxidoreductase FAD-binding subunit
M. avium 104MAV_0590-1e-2127.56% (312) oxidoreductase, electron transfer component

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3259c-0.083.16% (380) oxidoreductase
M. gilvum PYR-GCKMflv_4699-1e-17577.66% (385) ferredoxin
M. tuberculosis H37RvRv3230c-0.083.42% (380) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3549c-1e-16173.74% (377) putative oxidoreductase
M. marinum MMMAR_1314-0.080.73% (384) oxidoreductase
M. smegmatis MC2 155MSMEG_1885-1e-18078.33% (383) 2Fe-2S iron-sulfur cluster binding domain-containing protein
M. thermoresistible (build 8)TH_2872-1e-17175.85% (381) PUTATIVE 2Fe-2S iron-sulfur cluster binding domain protein
M. ulcerans Agy99MUL_2566-0.080.73% (384) oxidoreductase
M. vanbaalenii PYR-1Mvan_1767-1e-17977.89% (380) ferredoxin

CLUSTAL 2.0.9 multiple sequence alignment


Mb3259c|M.bovis_AF2122/97           ----MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPD
Rv3230c|M.tuberculosis_H37Rv        ----MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPD
MMAR_1314|M.marinum_M               ----MVKKNAALSAQIIDTKRPNIVGADKHPGWHALRKIASRITTPLLPD
MUL_2566|M.ulcerans_Agy99           ----MVKKNAALSAQIIDTKRPSIVGADKHPGWHALRKIASRITTPLLPD
MAV_4193|M.avium_104                MSNTMSKTTSPITANLGDTKRPVVAGAERHPGWHALRKLAARITTPLLPD
Mflv_4699|M.gilvum_PYR-GCK          ----MAKSTIKNTAKVADTVRPAVAGAKERPLWHALRTVAGRITTPLLPD
Mvan_1767|M.vanbaalenii_PYR-1       ----MAKNTIKNTAKVADTVRPTIAGAKENPGWHLLRTIAGRITTPLLPD
MSMEG_1885|M.smegmatis_MC2_155      ----MAKNHIKISANVADTVRPTVAGADERPGWHALRRLAARITTPLLPD
TH_2872|M.thermoresistible__bu      ----MAKSEIKYSARVVDTVRPQVAGVENRPVLHRLRRFAERITTPLLPD
MAB_3549c|M.abscessus_ATCC_199      ----------MKLASWLDASAPGAP-KSRHAAVNILRGLASRITTPLLPD
                                                 *   *:  *     ....  : ** .* *********

Mb3259c|M.bovis_AF2122/97           DYLHLANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYI
Rv3230c|M.tuberculosis_H37Rv        DYLHLANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYI
MMAR_1314|M.marinum_M               DYLQLANPLWSARELRGRILEVRRETEDSATLVIKPGWGFSFDYQPGQYI
MUL_2566|M.ulcerans_Agy99           DYLQLANPLWSARELRGRILEVRRETEDSATLVIKPGWGFSFDYQPGQYI
MAV_4193|M.avium_104                DYLHLANPLWSARELRGRVVDVRRETEDSATLVIKPGWGFNFDYQPGQYI
Mflv_4699|M.gilvum_PYR-GCK          DYLQLANPLWSARELRGRVLEVRRETVDSATLVIKPGWGFSFDYEAGQYI
Mvan_1767|M.vanbaalenii_PYR-1       DYLKLANPLWSARELRGRVLEVRRETEDSATLVIKPGWGFSFDYEPGQYI
MSMEG_1885|M.smegmatis_MC2_155      DYLQLANPLWSARELRGRVLEVRRETEDSATLVIKPGWGFSFDYQPGQYI
TH_2872|M.thermoresistible__bu      DYLHLINPLWSARELRGRVEDVRRETEDSATLVIKPGWGFSFDYQPGQYI
MAB_3549c|M.abscessus_ATCC_199      DYLSLANPLWSARELRGRVVSVRKETSDSATLEIKPGWGFHFDYHPGQYV
                                    *** * ************:  **:** ***** ******* ***..***:

Mb3259c|M.bovis_AF2122/97           GIGLLVDGCWRWRSYSLTSSPAAS------------GSARMVTVTVKAMP
Rv3230c|M.tuberculosis_H37Rv        GIGLLVDGRWRWRSYSLTSSPAAS------------GSARMVTVTVKAMP
MMAR_1314|M.marinum_M               GIGLLVDGRWRWRSYSLTSSPVGGK--------SGPGSARTVTITVKAMP
MUL_2566|M.ulcerans_Agy99           GIGLLVDGRWRWRSYSLTSSPVGGK--------SGPGSARTVTITVKAMP
MAV_4193|M.avium_104                GIGLLIDGRWRWRSYSLTSSPATS------------ASARTVTITVKAMP
Mflv_4699|M.gilvum_PYR-GCK          GIGLLVEGRWRWRSYSLTSPPAER---------PARS-ARTITITVKAMP
Mvan_1767|M.vanbaalenii_PYR-1       GIGLLVEGRWRWRSYSLTSSPVT-----------SKG-SRTITITVKAMP
MSMEG_1885|M.smegmatis_MC2_155      GIGVFLDGRWRWRSYSLTSSPVTA---------HPKGRARTITITVKAMP
TH_2872|M.thermoresistible__bu      GIGLPVDGRWRWRSYSLTSPAVTS---------GRGG--RTITITVKAMP
MAB_3549c|M.abscessus_ATCC_199      GIGVLIDGRWRWRSYSLTSAPAMSGSREERRALHAGGSARTITITVKAMP
                                    ***: ::* **********...              .  * :*:******

Mb3259c|M.bovis_AF2122/97           EGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVM
Rv3230c|M.tuberculosis_H37Rv        EGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVM
MMAR_1314|M.marinum_M               EGFLSTHLVAGVAPGTIVRLVAPQGNFVLPDPAPPSMLFLTAGSGITPVM
MUL_2566|M.ulcerans_Agy99           EGFLSTHLVAGVAPGTIVRLVAPQGNFVLPDPAPPSILFLTAGSGITPVM
MAV_4193|M.avium_104                EGFLSSHLVAGVEPGTVVRLAAPQGNFVLPDPAPASILFLTAGSGITPVM
Mflv_4699|M.gilvum_PYR-GCK          EGFLSTHLVGGVEPGAIVRLAAPQGNFVMPDPAPASVLFLTAGSGITPVM
Mvan_1767|M.vanbaalenii_PYR-1       EGFLSTHLVGGVAPGTIVRLAAPQGNFVMPDPAPASVLFLTAGSGITPVM
MSMEG_1885|M.smegmatis_MC2_155      EGFLSTHLVGGLEPGTVVRLAAPQGNFVMPDPAPASVLFLTAGSGITPVM
TH_2872|M.thermoresistible__bu      EGFLSTHLVEGVKPGTIVRLAAPQGNFVMPNPAPPQVLFLTAGSGITPIM
MAB_3549c|M.abscessus_ATCC_199      EGFLSTHLVNGLEPGTIVRLAAPQGNFVLDDPAPPAILFLTAGSGITPIM
                                    *****:*** *: **::***.*******: :***. :***********:*

Mb3259c|M.bovis_AF2122/97           SMLRTLVRR-----NQITDVVHLHSAPTAADVMFGAELAALAADHPGYRL
Rv3230c|M.tuberculosis_H37Rv        SMLRTLVRR-----NQITDVVHLHSAPTAADVMFGAELAALAADHPGYRL
MMAR_1314|M.marinum_M               SMLRTLLRR-----NQITDITHLHSVPTEADVMFGDELAGVAAQHPGYRL
MUL_2566|M.ulcerans_Agy99           SMLRTLLRR-----NQITDITHLHSVPTEADVMFGDELAGVAAQHPGYRL
MAV_4193|M.avium_104                SMLRTLVRR-----NQIGDIVHLHSAPTEADVMFRGELAALANEHPGYRL
Mflv_4699|M.gilvum_PYR-GCK          SMLRTLVRRDAI--GAPGHIVHVHSAPTEADIMFAAELAELARSHEGYRL
Mvan_1767|M.vanbaalenii_PYR-1       SMLRTLVRR-----GQLGDVAHVHSSPTEDDVMFAAELSELADRHEGYRL
MSMEG_1885|M.smegmatis_MC2_155      SMLRTLVRR-----DQITDIVHLHSAPTESDVLFGSELTALQGTHPGYRL
TH_2872|M.thermoresistible__bu      SMLRTLERR-----DQITDIVHIHSVPTPSDAMFSGELADLQRRHPSYRF
MAB_3549c|M.abscessus_ATCC_199      SMLRTLVRRSAAAGLPLPDVVHLHSAPTAGDVMFAGELAAFSEAHPSYHY
                                    ****** **         .:.*:** **  * :*  **: .   * .*: 

Mb3259c|M.bovis_AF2122/97           SVRETRAQGRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGAS
Rv3230c|M.tuberculosis_H37Rv        SVRETRAQGRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGAS
MMAR_1314|M.marinum_M               SVRATRSQGRLDLSRIGEQVPDWRERQTWACGPESMLNQAEKVWSAAGIG
MUL_2566|M.ulcerans_Agy99           SVRATRSQGRLDLSRIGEQVPDWRERQTWACGPESMLNQAEKVWSAAGIG
MAV_4193|M.avium_104                QLRETRTRGRLDLSLLDREVPDWRERQTWACGPEGMLNAAERVWSAAGIG
Mflv_4699|M.gilvum_PYR-GCK          ELRATRTQGRLDVGRLDDVVPDWRDRQTWACGPEAMLEDAERTWKSAGVG
Mvan_1767|M.vanbaalenii_PYR-1       RVRATRTEGRLDLDRLDEVVPDWRERQTWACGPEAMLEAAERTWKAAGIA
MSMEG_1885|M.smegmatis_MC2_155      RIRSTRTEGRLDLERIADEVPDWRERQVWACGPEGMLADAERVWKAAGVG
TH_2872|M.thermoresistible__bu      RLRTTRTEGRLDLSRLDDEVGDWRSRQTWACGPEGLLTAAERVWLGAGIG
MAB_3549c|M.abscessus_ATCC_199      RLRTTKTQGRLDFSSLAAEVPDWARRQTWACGPEGMLDDAQRTWADAGLA
                                     :* *::.****.  :   * **  **.******.:*  *::.*  ** .

Mb3259c|M.bovis_AF2122/97           DRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMDAGEGAGVQL
Rv3230c|M.tuberculosis_H37Rv        DRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMDAGEGAGVQL
MMAR_1314|M.marinum_M               DRLHLERFAVSKAAPAGAGGTVTFARSGRSVDVDAATSVMDAGERAGVQM
MUL_2566|M.ulcerans_Agy99           DRLHLERFAVSKAAPAGAGGTVTFARSGRSVDVDAATSVMDAGERAGVQM
MAV_4193|M.avium_104                EQLHLERFAVSKAAPAGAGGMVTFARSGRSVDADAATSLMDAGEAAGVQM
Mflv_4699|M.gilvum_PYR-GCK          ERLHQERFAVSRAPVHGSGGTVTFARSDRTVTVDAATSLMDAGEDAGVQM
Mvan_1767|M.vanbaalenii_PYR-1       DRLHLERFAVARA-AHGSGGTVEFSRSGKAATVDGATSLMDAGEAAGIQM
MSMEG_1885|M.smegmatis_MC2_155      ENLHLERFAVKRAAPHGTGGNVTFERTGKTVHADAAKSLMEAGEEVGIRM
TH_2872|M.thermoresistible__bu      DRLHLERFAVARVANPGGGGTIEFARSGKSTVVDAATSLMDAGEQAGVQM
MAB_3549c|M.abscessus_ATCC_199      ELLHLERFAVSRAAPHGQGGLVTFARSGKQRAADAATSLMEAGEEAGVQM
                                    : ** ***** :.   * ** : * *:.:   .*.*.*:*:*** .*:::

Mb3259c|M.bovis_AF2122/97           PFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLD
Rv3230c|M.tuberculosis_H37Rv        PFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLD
MMAR_1314|M.marinum_M               PFGCRMGICQSCVVDLVQGHVRDLRTGQEHDPGSRVQTCVTAASGDCVID
MUL_2566|M.ulcerans_Agy99           PFGCRMGICQSCVVDLVQGHVRDLRTGQEHDPGSRVQTCVTAASGDCAID
MAV_4193|M.avium_104                PFGCRMGICQSCVVGLVEGHVRDLRTGAEHEPGTRVQTCVSAASGDCVLD
Mflv_4699|M.gilvum_PYR-GCK          PFGCRMGICQSCVVGLVEGHVRDLRTGIEHEPGSRVQTCVTAASGDCVLD
Mvan_1767|M.vanbaalenii_PYR-1       PFGCRMGICQSCVVGLLDGHVRDLRTGVEHEPGTRVQTCVSAASGDCVLD
MSMEG_1885|M.smegmatis_MC2_155      PFGCRMGICQSCVVGLVDGHVRDLRTGVEHDAGSRIQTCVSAASGDCVLD
TH_2872|M.thermoresistible__bu      PFGCRMGICQSCVIGLVDGHVRDLRTGEVHDPGTRVQTCVSAAAGDCVLD
MAB_3549c|M.abscessus_ATCC_199      PFGCRMGICQTCVVSLVQGHARDLRTGAEYEPGTRIQTCVSAASGDCVLD
                                    **********:**:.*::**.******  ::.*:*:****:**:***.:*

Mb3259c|M.bovis_AF2122/97           I
Rv3230c|M.tuberculosis_H37Rv        I
MMAR_1314|M.marinum_M               V
MUL_2566|M.ulcerans_Agy99           V
MAV_4193|M.avium_104                I
Mflv_4699|M.gilvum_PYR-GCK          V
Mvan_1767|M.vanbaalenii_PYR-1       V
MSMEG_1885|M.smegmatis_MC2_155      V
TH_2872|M.thermoresistible__bu      I
MAB_3549c|M.abscessus_ATCC_199      V
                                    :