For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NAAPLPRDSTDDAREAQRVVAALADAFSAKVVGQEHLRETLLIGLLTGGHILLESVPGLAKTTAARVVAE AIDGQFRRIQCTPDLLPSDIIGTQVYDAATTSFVTQLGPVHANVVLLDEINRSSAKTQSAMLEAMEERQT TIAGVVYPIPEPFLVIATQNPVDQEGTYALSEAQTDRFLLKEIVRYPSPEQEVEVLARLDAGLFDKAHPV RPVATLDDIRRLQRVTRDVYMSRDLMLYASRLVGVTREPGNYLPGQVARLIEYGASPRATIALCTAARAL ALLSGRNHVVPGDIADLAHRVLQHRLILGFEAASAGITPDVVVDAVLRAVRVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0879 | - | - | 100% (334) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_2749 | - | 2e-74 | 46.89% (305) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_5455 | - | 2e-65 | 43.75% (320) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1515 | moxR1 | 3e-75 | 45.87% (303) | transcriptional regulatory protein MOXR1 |
| M. gilvum PYR-GCK | Mflv_0039 | - | 1e-166 | 88.02% (334) | ATPase |
| M. tuberculosis H37Rv | Rv1479 | moxR1 | 3e-75 | 45.87% (303) | transcriptional regulatory protein MOXR1 |
| M. leprae Br4923 | MLBr_01810 | moxR | 5e-75 | 46.05% (304) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_0653 | - | 1e-121 | 64.67% (334) | MoxR-like ATPase |
| M. marinum M | MMAR_2286 | moxR1 | 6e-75 | 46.89% (305) | transcriptional regulatory protein, MoxR1 |
| M. avium 104 | MAV_3299 | - | 6e-76 | 46.89% (305) | MoxR protein |
| M. smegmatis MC2 155 | MSMEG_6612 | moxR | 1e-141 | 77.33% (322) | ATPase, MoxR family protein |
| M. thermoresistible (build 8) | TH_0628 | moxR | 1e-130 | 70.90% (323) | ATPase, MoxR family protein |
| M. ulcerans Agy99 | MUL_1488 | moxR1 | 4e-75 | 46.89% (305) | transcriptional regulatory protein, MoxR1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2286|M.marinum_M MTSAGG------GYSGPGGHSAPPAHEAPSGGP---DGLAAEVHTLERAI
MUL_1488|M.ulcerans_Agy99 MTSAGG------GYSGPGGHSAPPAHEAPSGGP---DGLAAEVHTLERAI
Mb1515|M.bovis_AF2122/97 MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGA---EGLAAEVHTLERAI
Rv1479|M.tuberculosis_H37Rv MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGA---EGLAAEVHTLERAI
MLBr_01810|M.leprae_Br4923 MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGA---DGLVAEVHTLERAI
MAV_3299|M.avium_104 MTAAGGPPPGAGGYSGPGGQSGPGAHEAPTGGAGAGNGLAAEVQTLERAI
Mvan_0879|M.vanbaalenii_PYR-1 MNAAPLP-----------RDSTDDAREAQ------------RVVAALADA
Mflv_0039|M.gilvum_PYR-GCK MTAAPMP-----------RES-DDAREAQ------------RVVAALSEA
MSMEG_6612|M.smegmatis_MC2_155 MTAPRLQ-----------LDQ-RDVAEAQ------------QIVGAVTSA
TH_0628|M.thermoresistible__bu MTAARLQ-----------LNR-EDLEEAR------------RIVDAVSAA
MAB_0653|M.abscessus_ATCC_1997 MTAATQT-----------QPSRQELDQAR------------AVIQAVARA
*.:. :* :
MMAR_2286|M.marinum_M FEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGG
MUL_1488|M.ulcerans_Agy99 FEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGG
Mb1515|M.bovis_AF2122/97 FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
Rv1479|M.tuberculosis_H37Rv FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
MLBr_01810|M.leprae_Br4923 FEVKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGG
MAV_3299|M.avium_104 FEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFAKVVGG
Mvan_0879|M.vanbaalenii_PYR-1 FSAK--VVGQEHLRETLLIGLLTGGHILLESVPGLAKTTAARVVAEAIDG
Mflv_0039|M.gilvum_PYR-GCK FSAK--VVGQEHLRETLLIGLLTGGHILLESVPGLAKTTAARVIAESIDG
MSMEG_6612|M.smegmatis_MC2_155 FSAK--VVGQDHLRESMLVALLSGGHLLLESVPGLAKTTAARVIAESIDG
TH_0628|M.thermoresistible__bu FSQK--VVGQHDLRESLLISLLAGGHILLESVPGLAKTTAARVIADTIHG
MAB_0653|M.abscessus_ATCC_1997 FSVK--VVGQSGLQQSLLIGLLTGGHVLLESVPGLAKTTAARAIADAIQA
*. * :*** * : :*:.**: **:***.***:*** *....* : .
MMAR_2286|M.marinum_M SFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANFLLADEINRAP
MUL_1488|M.ulcerans_Agy99 SFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANFLLADEINRAP
Mb1515|M.bovis_AF2122/97 TFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAP
Rv1479|M.tuberculosis_H37Rv TFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANFLLADEINRAP
MLBr_01810|M.leprae_Br4923 TFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAP
MAV_3299|M.avium_104 TFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAP
Mvan_0879|M.vanbaalenii_PYR-1 QFRRIQCTPDLLPSDIIGTQVYDAATTSFVTQLGPVHANVVLLDEINRSS
Mflv_0039|M.gilvum_PYR-GCK EFRRIQCTPDLLPSDIIGTQVYDATTTAFVTQLGPVHANVVLLDEINRSS
MSMEG_6612|M.smegmatis_MC2_155 SFHRIQCTPDLLPSDIIGTQVYEAATHSFTTQLGPVHANIVLLDEINRSS
TH_0628|M.thermoresistible__bu GFQRIQCTPDLLPSDIIGTQVYDAATNAFVTRLGPVHTNIVLLDEINRSS
MAB_0653|M.abscessus_ATCC_1997 QFRRIQCTPDLLPSDIIGTQIFDASKGTFKTQLGPVHANIVLLDEINRSS
* *** ****:*:**:**::: * *.**** .*.:* *****:.
MMAR_2286|M.marinum_M AKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLPEAQ
MUL_1488|M.ulcerans_Agy99 AKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLPEAQ
Mb1515|M.bovis_AF2122/97 AKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQ
Rv1479|M.tuberculosis_H37Rv AKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLPEAQ
MLBr_01810|M.leprae_Br4923 AKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQ
MAV_3299|M.avium_104 AKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYPLPEAQ
Mvan_0879|M.vanbaalenii_PYR-1 AKTQSAMLEAMEERQTTIAGVVYPIPEPFLVIATQNPVDQEGTYALSEAQ
Mflv_0039|M.gilvum_PYR-GCK AKTQSAMLEAMEERQTTIAGTVYPIPEPFLVIATQNPVDQEGTYALSEAQ
MSMEG_6612|M.smegmatis_MC2_155 AKTQSAMLEAMEERQTTIAGVEYPIPEPFLVIATQNPVDQEGTYPLSEAQ
TH_0628|M.thermoresistible__bu AKTQSAMLEAMEERQTTIAGTVYPIPEPFLVIATQNPVDQEGTYPLSEAQ
MAB_0653|M.abscessus_ATCC_1997 AKTQSAMLEAMEERQTSIAGEIYKIPEPFLVLATQNPVDQEGTYPLPEAQ
**.***:**.* **:.:*.* : :*.****:*****:::**.* *.***
MMAR_2286|M.marinum_M RDRFLFKINVGYPTPEEEREIIYRMGV----TPPQPKQILGTGDLLRLQD
MUL_1488|M.ulcerans_Agy99 RDRFLFKINVGYPTPEEEREIIYRMGV----TPPQPKQILGTGDLLRLQD
Mb1515|M.bovis_AF2122/97 RDRFLFKINVGYPSPEEEREIIYRMGV----TPPQAKQILSTGDLLRLQE
Rv1479|M.tuberculosis_H37Rv RDRFLFKINVGYPSPEEEREIIYRMGV----TPPQAKQILSTGDLLRLQE
MLBr_01810|M.leprae_Br4923 RDRFLFKINVGYPSPEEEREIIYRMGV----TPPVPKQILNAGDLLRLQE
MAV_3299|M.avium_104 RDRFLFKINVGYPSPEEEREIIYRMGV----RPPEPKQILNTGDLVRLQD
Mvan_0879|M.vanbaalenii_PYR-1 TDRFLLKEIVRYPSPEQEVEVLARLDAGLFDKAHPVRPVATLDDIRRLQR
Mflv_0039|M.gilvum_PYR-GCK TDRFLLKEIVRYPSPEQEVDMMSRRDAGLYDKDHRSSPVVGLDDVRRLQR
MSMEG_6612|M.smegmatis_MC2_155 TDRFMLKEIVRYPSVADEVEMIARMDAGLYERGRHGTPVVGIDDVRRVQR
TH_0628|M.thermoresistible__bu TDRFMLKDILDYPSPQQEAEVIFRMDAGVYNRNQPTPPVVGLEDMRRLQE
MAB_0653|M.abscessus_ATCC_1997 MDRFMFKEILTYPNPAEEAEVVFRIDAGVYTN-HQGAPVASIQDILYIQD
***::* : **. :* ::: * .. : *: :*
MMAR_2286|M.marinum_M IAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLGII
MUL_1488|M.ulcerans_Agy99 IAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLGII
Mb1515|M.bovis_AF2122/97 IAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLGII
Rv1479|M.tuberculosis_H37Rv IAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLGII
MLBr_01810|M.leprae_Br4923 ISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGII
MAV_3299|M.avium_104 IAANVFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGII
Mvan_0879|M.vanbaalenii_PYR-1 VTRDVYMSRDLMLYASRLVGVTREPGNYLPGQVARLIEYGASPRATIALC
Mflv_0039|M.gilvum_PYR-GCK ITRDVYMSRDLMLYASRLVGVTREPGNHLPSQLARMVEYGASPRATIALC
MSMEG_6612|M.smegmatis_MC2_155 IAESVHLDRALVEYAGRLVGVTREPDSFLPTNLARLVEYGASPRATIALC
TH_0628|M.thermoresistible__bu LVGRIHLDPVLVHYVTQLVHVTRNPQQYLPQQLARLVQYGASPRATIAFC
MAB_0653|M.abscessus_ATCC_1997 VVRRIYVDPAIVHYVTQIVNVTRNPKQYLPPNLARLIEYGASPRATIAFC
: .: :: *. ::* .**.* . :: : :******::.:
MMAR_2286|M.marinum_M AASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIVIN
MUL_1488|M.ulcerans_Agy99 AASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIVIN
Mb1515|M.bovis_AF2122/97 AAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIVIN
Rv1479|M.tuberculosis_H37Rv AAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIVIN
MLBr_01810|M.leprae_Br4923 KASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEIVIN
MAV_3299|M.avium_104 AGARSLALVRGRDYVIPQDVVDVIPDVLRHRLVLTYDALADEISPEIVIN
Mvan_0879|M.vanbaalenii_PYR-1 TAARALALLSGRNHVVPGDIADLAHRVLQHRLILGFEAASAGITPDVVVD
Mflv_0039|M.gilvum_PYR-GCK TAARALAVLSGRDHVIPSDIADLAHRVLQHRLILGFEAASAGVTPNRVID
MSMEG_6612|M.smegmatis_MC2_155 RTARALALLRGRDHVVPDDIARLAHRVLRHRLILGFEAASARITPDVVID
TH_0628|M.thermoresistible__bu RSARAVALLQGRNHVLPDDIQRVAHRVLRHRLILGFEAMRLNVTPEMVID
MAB_0653|M.abscessus_ATCC_1997 KAARALALLADRNHVLPDDIKALAHRILRHRLILGFEAVAENVTAEVLID
:*::*:: .*::*:* *: : :*:***:* ::* ::.: :::
MMAR_2286|M.marinum_M RVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
MUL_1488|M.ulcerans_Agy99 RVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
Mb1515|M.bovis_AF2122/97 RVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
Rv1479|M.tuberculosis_H37Rv RVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
MLBr_01810|M.leprae_Br4923 RVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR
MAV_3299|M.avium_104 RVLQTVALPQVNAVPQQGHSVPPVMQPAGAASGR
Mvan_0879|M.vanbaalenii_PYR-1 AVLRAVRVP-------------------------
Mflv_0039|M.gilvum_PYR-GCK AVLHAVRVP-------------------------
MSMEG_6612|M.smegmatis_MC2_155 AVLAAVRVP-------------------------
TH_0628|M.thermoresistible__bu AVLQSVRVP-------------------------
MAB_0653|M.abscessus_ATCC_1997 NIIQAVRTP-------------------------
:: :* *