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GMTPSSFGGSGRSSRDNRGLYNPAYEHDACGVAMVADMHGRRSRDIVDKAITALVNLEHRGAQGAEPNTG DGAGILIQVPDAFLRAVVDFDLPEPGSYATGMAFLPQSSRDAAAACESVEKIAEAEGLEVLGWREVPTDD SSLGALARDAMPTFRQLFLGGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQTFVYK GMLTTPQLKQFYLDLQDERLESALGIVHSRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREAL IRTDVFGSDGLDKIVPVCTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHEDMDPARRAFYEY HASLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLPLDPAKVVKKMRLQPGR MFLVDTAQGRIVDDEEVKAELAAAEPYQEWLEQGLFHLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNL LVAPMARTGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREEVVTSLQGTVGPEGDLL NPGPESCRQIVLPQPILRNADLSKLICVDPDHEIRGHKHGMRAAVIRCLYPVNRGGVGLKEALDNVRAKV SEAIREGARIIVLSDRESNETMAPIPSLLSVAAVHHHLVRERTRTKVGLVVEAGDAREVHHMATLVGFGA AAINPYMAFESIEDMVDRGVITGLTSDQAKANYVKAAGKGVLKVMSKMGISTLASYTGAQLFQAIGISQQ VLDEYFTGLSCPVGGIDLEDIAADVAARHSLAFLDRPDERAHRELEVGGEYQWRREGEYHLFNPDTVFKL QHSTRTGQYSIFKEYTKLVDDQSERIASLRGLLKFREGHRPPVPIEEVEPASEIVKRFSTGAMSYGSISA EAHETLAIAMNRLGGRSNSGEGGEAVHRFNPDENGDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQG AKPGEGGQLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARIHVKLVSENG VGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGLAETQQTLLLNGLRDRIVVQVDGQLKT GRDVVIAALLGAEEFGFATAPLVVSGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEE VRELMAQLGFRTVNEMVGQVGALDTTKAAEHWKAHKLDLTPVLHEPDSAFMNQDLYCSSRQDHGLDKALD QQLIVQSREALDSGTPVRFTAKITNVNRTVGTMLGHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPK GITLRVYGDANDYVGKGLSGGRIVVRPADEAPESFAAEDNIIAGNVVLFGATSGEAFLRGQVGERFAVRN SGAVAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYVYDPRAALPKNLNPEMVEIEALEEADT EWLRGILASHVDATDSAVGQRILADWDNELKHFAKVMPRDYKRVLAAIAEAEAKGLTGSDIDDAIMAASN G*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6459 | - | - | 100% (1542) | ferredoxin-dependent glutamate synthase 1 |
M. smegmatis MC2 155 | MSMEG_3225 | - | 0.0 | 63.62% (1542) | ferredoxin-dependent glutamate synthase 1 |
M. smegmatis MC2 155 | MSMEG_5594 | - | 1e-33 | 34.07% (270) | ferredoxin-dependent glutamate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3889c | gltB | 0.0 | 84.91% (1524) | putative ferredoxin-dependent glutamate synthase |
M. gilvum PYR-GCK | Mflv_1114 | - | 0.0 | 89.59% (1528) | glutamate synthase (ferredoxin) |
M. tuberculosis H37Rv | Rv3859c | gltB | 0.0 | 84.91% (1524) | ferredoxin-dependent glutamate synthase |
M. leprae Br4923 | MLBr_00061 | gltB | 0.0 | 82.09% (1524) | putative ferredoxin-dependent glutamate synthase |
M. abscessus ATCC 19977 | MAB_0091 | - | 0.0 | 82.20% (1528) | putative ferredoxin-dependent glutamate synthase |
M. marinum M | MMAR_5413 | gltB | 0.0 | 84.45% (1524) | ferredoxin-dependent glutamate synthase |
M. avium 104 | MAV_0166 | - | 0.0 | 85.17% (1524) | ferredoxin-dependent glutamate synthase 1 |
M. thermoresistible (build 8) | TH_2102 | gltB | 0.0 | 88.15% (1528) | PROBABLE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE |
M. ulcerans Agy99 | MUL_5037 | gltB | 0.0 | 84.12% (1524) | ferredoxin-dependent glutamate synthase |
M. vanbaalenii PYR-1 | Mvan_5698 | - | 0.0 | 90.49% (1514) | glutamate synthase (ferredoxin) |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1114|M.gilvum_PYR-GCK -------------MAPSRQGLYDPAFEHDSCGVAMVADIHGRRSRDIVEK Mvan_5698|M.vanbaalenii_PYR-1 ----------------------------------MVADMHGRRSRDIVDK MSMEG_6459|M.smegmatis_MC2_155 MGMTPSSFGGSGRSSRDNRGLYNPAYEHDACGVAMVADMHGRRSRDIVDK TH_2102|M.thermoresistible__bu -------------MTPKAQGLYNPAFEHDACGVAMVADMYGRRSRDIVDK Mb3889c|M.bovis_AF2122/97 -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK Rv3859c|M.tuberculosis_H37Rv -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK MLBr_00061|M.leprae_Br4923 -------------MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDK MAV_0166|M.avium_104 -----------MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDK MMAR_5413|M.marinum_M -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK MUL_5037|M.ulcerans_Agy99 -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK MAB_0091|M.abscessus_ATCC_1997 -------------MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDK **.*::***:****:* Mflv_1114|M.gilvum_PYR-GCK AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVC----GFDLPEP Mvan_5698|M.vanbaalenii_PYR-1 AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVCEKE-GFDLPEA MSMEG_6459|M.smegmatis_MC2_155 AITALVNLEHRGAQGAEPNTGDGAGILIQVPDAFLRAVV----DFDLPEP TH_2102|M.thermoresistible__bu AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFLRAVVEEQGDFELPPP Mb3889c|M.bovis_AF2122/97 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP Rv3859c|M.tuberculosis_H37Rv AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP MLBr_00061|M.leprae_Br4923 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLRAVV----DFELPAA MAV_0166|M.avium_104 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLREVV----DFELPPE MMAR_5413|M.marinum_M AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP MUL_5037|M.ulcerans_Agy99 AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP MAB_0091|M.abscessus_ATCC_1997 AITALLNLEHRGAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAE *****:******* ****.:******::*:** *:* . .*:** Mflv_1114|M.gilvum_PYR-GCK GSFATGIAFLPQSAKDAATACESVEKIAEAEGLRVLGWRDVPTDDSSLGA Mvan_5698|M.vanbaalenii_PYR-1 GSYATGMAFLPQSSKDAAIACAAVEKIAEAEGLQVLGWRDVPTDDSSLGA MSMEG_6459|M.smegmatis_MC2_155 GSYATGMAFLPQSSRDAAAACESVEKIAEAEGLEVLGWREVPTDDSSLGA TH_2102|M.thermoresistible__bu GSYATGIAFLPQSAKDAAQACDAVEKIVEAEGLTVLGWREVPIDDSSLGA Mb3889c|M.bovis_AF2122/97 GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA Rv3859c|M.tuberculosis_H37Rv GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA MLBr_00061|M.leprae_Br4923 SSYATGIAFLPQSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGA MAV_0166|M.avium_104 GSYATGIAFLPQSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGA MMAR_5413|M.marinum_M GSYATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTDDSSLGA MUL_5037|M.ulcerans_Agy99 GSYATGIAFLPQSSKDAAAACAAVEKIGEAEGLQVLGWRNVPTDDSSLGA MAB_0091|M.abscessus_ATCC_1997 GSYASGIAFLPQGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGA .*:*:*:*****.::*** ** :*:** **** *****.** * ***** Mflv_1114|M.gilvum_PYR-GCK LARDAMPTFRQVFMAGAEGMDLERRAYVVRKRAEHELGTKGPGQDGPGRE Mvan_5698|M.vanbaalenii_PYR-1 LARDAMPTFRQIFLAGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE MSMEG_6459|M.smegmatis_MC2_155 LARDAMPTFRQLFLGGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE TH_2102|M.thermoresistible__bu LARDAMPTFRQLFLGGATGIDLERRAYVVRKRAEHELGTKGPGQDGPGRE Mb3889c|M.bovis_AF2122/97 LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE Rv3859c|M.tuberculosis_H37Rv LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE MLBr_00061|M.leprae_Br4923 LSRDAMPTFRQVFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRE MAV_0166|M.avium_104 LSRDAMPTFRQVFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRE MMAR_5413|M.marinum_M LSRDAMPTFRQVFLAGASDMTLERRCYVIRKRAEHELGTKGPGQDGPGRE MUL_5037|M.ulcerans_Agy99 LSRDAMPTFRQVFLAGASDMALERRCYVIRKRAEHELGTKGPGQDGPGRE MAB_0091|M.abscessus_ATCC_1997 LARDAMPTFRQLFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEE *:*********:*:.** .: **** *::*** *****.:*.*:.. *.* Mflv_1114|M.gilvum_PYR-GCK TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT Mvan_5698|M.vanbaalenii_PYR-1 TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT MSMEG_6459|M.smegmatis_MC2_155 TVYFPSLSGQTFVYKGMLTTPQLKQFYLDLQDERLESALGIVHSRFSTNT TH_2102|M.thermoresistible__bu TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERLTSALAIVHSRFSTNT Mb3889c|M.bovis_AF2122/97 TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT Rv3859c|M.tuberculosis_H37Rv TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT MLBr_00061|M.leprae_Br4923 TIYFPSLSSQTFVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNT MAV_0166|M.avium_104 TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT MMAR_5413|M.marinum_M TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT MUL_5037|M.ulcerans_Agy99 TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT MAB_0091|M.abscessus_ATCC_1997 TVYFPSLSGRTFVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNT *:******.:*:***********: ** ****:*: ***.********** Mflv_1114|M.gilvum_PYR-GCK FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDVFGAKADLDKI Mvan_5698|M.vanbaalenii_PYR-1 FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDIFGGQ-DLEKV MSMEG_6459|M.smegmatis_MC2_155 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDVFGSD-GLDKI TH_2102|M.thermoresistible__bu FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDLFGGQ-DLEKV Mb3889c|M.bovis_AF2122/97 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL Rv3859c|M.tuberculosis_H37Rv FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL MLBr_00061|M.leprae_Br4923 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKL MAV_0166|M.avium_104 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKL MMAR_5413|M.marinum_M FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL MUL_5037|M.ulcerans_Agy99 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL MAB_0091|M.abscessus_ATCC_1997 FPSWPLAHPYRRVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKI *********:**:*********:************::**:** ::*: Mflv_1114|M.gilvum_PYR-GCK TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR Mvan_5698|M.vanbaalenii_PYR-1 TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR MSMEG_6459|M.smegmatis_MC2_155 VPVCTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHEDMDPAR TH_2102|M.thermoresistible__bu APICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWEQHESMDPAR Mb3889c|M.bovis_AF2122/97 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR Rv3859c|M.tuberculosis_H37Rv FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR MLBr_00061|M.leprae_Br4923 FPICTPGASDTARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPAR MAV_0166|M.avium_104 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR MMAR_5413|M.marinum_M FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR MUL_5037|M.ulcerans_Agy99 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR MAB_0091|M.abscessus_ATCC_1997 FPICTRGASDTARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAEL *:** **********.*********.* ************:* .*.. Mflv_1114|M.gilvum_PYR-GCK RAFYEFHDSLMEPWDGPAAVCFTDGTVIGAVLDRNGLRPSRIWVTEDGLV Mvan_5698|M.vanbaalenii_PYR-1 RAFYQYHASLMEPWDGPAAVCFTDGTVVGAVLDRNGLRPSRIWVTSDGLV MSMEG_6459|M.smegmatis_MC2_155 RAFYEYHASLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTDDGLV TH_2102|M.thermoresistible__bu RAFYEFHDSLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTADGLV Mb3889c|M.bovis_AF2122/97 RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV Rv3859c|M.tuberculosis_H37Rv RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV MLBr_00061|M.leprae_Br4923 RAFYQYHASLMEPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLV MAV_0166|M.avium_104 RAFYQYHASLMEPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLV MMAR_5413|M.marinum_M RAFYQYHSSLMEPWDGPASMTFTDGTIIGAVLDRNGLRPSRIWVTEDGLV MUL_5037|M.ulcerans_Agy99 RAFYQYHSSLMEPWDGPASMTFTDGTMVGAVLDRNGLRPSRIWVTEDGLV MAB_0091|M.abscessus_ATCC_1997 RSFYEFHASLMEPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLV *:**::* **********:: ****.::*************:*:* *** Mflv_1114|M.gilvum_PYR-GCK VMASEAGVLDLDPSTVVKKMRLQPGRMFLVDTAQGRIVDDEEIKAQLAAE Mvan_5698|M.vanbaalenii_PYR-1 VMASEAGVLDLDPGTVVQKMRLQPGRMFLVDTAQGRIVSDEEIKAELAAG MSMEG_6459|M.smegmatis_MC2_155 VMASEAGVLPLDPAKVVKKMRLQPGRMFLVDTAQGRIVDDEEVKAELAAA TH_2102|M.thermoresistible__bu VMASEAGVLNLDPATVVRKMRLQPGRMFLVDTAQGRIIDDEEIKAELAAE Mb3889c|M.bovis_AF2122/97 VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE Rv3859c|M.tuberculosis_H37Rv VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE MLBr_00061|M.leprae_Br4923 VMASEAGVLDLDPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAE MAV_0166|M.avium_104 VMASEAGVLDLDPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE MMAR_5413|M.marinum_M VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE MUL_5037|M.ulcerans_Agy99 VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEAIKAELAAE MAB_0091|M.abscessus_ATCC_1997 VMASEAGVLDLDPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAA ********* *.*. **:: ************:****:.** :**.*** Mflv_1114|M.gilvum_PYR-GCK HPYQEWLDAGLFQLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP Mvan_5698|M.vanbaalenii_PYR-1 QPYQEWLDAGLFHLDELPQGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP MSMEG_6459|M.smegmatis_MC2_155 EPYQEWLEQGLFHLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP TH_2102|M.thermoresistible__bu HPYQEWLDAGLFPLDELPQGDYQRMPHHRVVLRQRVFGYTSEELNLIVGP Mb3889c|M.bovis_AF2122/97 HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP Rv3859c|M.tuberculosis_H37Rv HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP MLBr_00061|M.leprae_Br4923 HPYQEWLDKGLVPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAP MAV_0166|M.avium_104 HPYQEWLDRNLVPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAP MMAR_5413|M.marinum_M HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP MUL_5037|M.ulcerans_Agy99 HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP MAB_0091|M.abscessus_ATCC_1997 EPYQRWLEEGLVRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAP .***.**: .*. ::.** :*.*.*:* ** **** **:**:*.* Mflv_1114|M.gilvum_PYR-GCK MARNGAEALGSMGTDTPIAVLSSRPRMLYDYFQQLFAQVTNPPLDAIREE Mvan_5698|M.vanbaalenii_PYR-1 MARSGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE MSMEG_6459|M.smegmatis_MC2_155 MARTGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE TH_2102|M.thermoresistible__bu MARTGAEPLGSMGTDTPIAVLSQRSRLLFDYFQQMFAQVTNPPLDAIREE Mb3889c|M.bovis_AF2122/97 MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE Rv3859c|M.tuberculosis_H37Rv MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE MLBr_00061|M.leprae_Br4923 MVRAGSEPIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREE MAV_0166|M.avium_104 MVRTGAEPIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREE MMAR_5413|M.marinum_M MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE MUL_5037|M.ulcerans_Agy99 MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE MAB_0091|M.abscessus_ATCC_1997 MARTGAEALGSMGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREE *.* *:*.:****:***:**** *.*:*:***:*:*************** Mflv_1114|M.gilvum_PYR-GCK VVTSLQGAMGPEGDLLNPGPESCRQIVLPQPILRNAELSKLICVDPDHEI Mvan_5698|M.vanbaalenii_PYR-1 VVTSLQGTVGPEGDLLNPDAESCRQIVLPNPILRNAELSKLICVDPDHEI MSMEG_6459|M.smegmatis_MC2_155 VVTSLQGTVGPEGDLLNPGPESCRQIVLPQPILRNADLSKLICVDPDHEI TH_2102|M.thermoresistible__bu VITSLQGVIGPEGDLLNPGPESCRQIVLPQPILRNHELAKLINVDPDHEV Mb3889c|M.bovis_AF2122/97 VVTSLQGTTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKV Rv3859c|M.tuberculosis_H37Rv VVTSLQGTTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKV MLBr_00061|M.leprae_Br4923 VVTSLQGTTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEV MAV_0166|M.avium_104 VVTSLQGTTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEV MMAR_5413|M.marinum_M VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI MUL_5037|M.ulcerans_Agy99 VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI MAB_0091|M.abscessus_ATCC_1997 VVTSLGGVIGPEGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTV *:*** *. * * *** * **:** *.:*:*:* :* **: ::* : Mflv_1114|M.gilvum_PYR-GCK RGHKHGMRAAVIRCLYPVNRGGQGLKEALDNVRAKVSSAIRDGARIIVLS Mvan_5698|M.vanbaalenii_PYR-1 RGHKHGMRAAVIRCLYPVNRGGRGLKEALDNVRAKVSAAIRDGARIIVLS MSMEG_6459|M.smegmatis_MC2_155 RGHKHGMRAAVIRCLYPVNRGGVGLKEALDNVRAKVSEAIREGARIIVLS TH_2102|M.thermoresistible__bu RGRKHGMRAAVVRCLFPVNRGGQGLKEALDRVRAKVSAAIREGARIIVLS Mb3889c|M.bovis_AF2122/97 NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS Rv3859c|M.tuberculosis_H37Rv NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS MLBr_00061|M.leprae_Br4923 NGRPHGMRSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILS MAV_0166|M.avium_104 NGRPHGMRSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILS MMAR_5413|M.marinum_M NGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADGARIIVLS MUL_5037|M.ulcerans_Agy99 NGRPHGLKSKVVRCLYPVAEGGSGLAAALNEVRAQASAAIADGARIIVLS MAB_0091|M.abscessus_ATCC_1997 NGRAHGFSSRVIRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILS .*: **: : *: **: * .* ** ** **. .: ** **::*:** Mflv_1114|M.gilvum_PYR-GCK DRESDEQMAPIPSLLSVSAVHHHLVRERTRTQVGLIVEAGDAREVHHMAA Mvan_5698|M.vanbaalenii_PYR-1 DRESNEQMAPIPSLLSVSAVHHHLVRDRTRTKVGLVVEAGDAREVHHMAA MSMEG_6459|M.smegmatis_MC2_155 DRESNETMAPIPSLLSVAAVHHHLVRERTRTKVGLVVEAGDAREVHHMAT TH_2102|M.thermoresistible__bu DRESDEQLAPIPSLLSVAAVHHHLVRDRTRTQVGLVVEAGDAREVHHMAA Mb3889c|M.bovis_AF2122/97 DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA Rv3859c|M.tuberculosis_H37Rv DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA MLBr_00061|M.leprae_Br4923 DRNSDEQMAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAA MAV_0166|M.avium_104 DRESDEKMAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAA MMAR_5413|M.marinum_M DRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAREVHHMAM MUL_5037|M.ulcerans_Agy99 DRESDERMAPIPALLAVAGVHHHLVRERTRTKVGLVVESGDAREVHHMAM MAB_0091|M.abscessus_ATCC_1997 DRESDDLMAPIPSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAA **:*:: :****:**:*:.*******:*:**:***:**:********:* Mflv_1114|M.gilvum_PYR-GCK LCGFGAAAINPYMAFESIEDMVDRGVITDITSDQAKANYVKAAGKGVLKV Mvan_5698|M.vanbaalenii_PYR-1 LCGFGAAAINPYMAFESIEDMVDRGVISGISSDQAKANYVKAAGKGVLKV MSMEG_6459|M.smegmatis_MC2_155 LVGFGAAAINPYMAFESIEDMVDRGVITGLTSDQAKANYVKAAGKGVLKV TH_2102|M.thermoresistible__bu LIGFGASAINPYLAFESIEDMLDRNLLEGLDRETALNNYIKAAGKGVLKV Mb3889c|M.bovis_AF2122/97 LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV Rv3859c|M.tuberculosis_H37Rv LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV MLBr_00061|M.leprae_Br4923 LIGFGAAAVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKI MAV_0166|M.avium_104 LVGFGAAAINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKV MMAR_5413|M.marinum_M LLGCGAAAVNPYLAFESIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV MUL_5037|M.ulcerans_Agy99 LLGCGAAAVNPYLAFASIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV MAB_0091|M.abscessus_ATCC_1997 LVGFGAAAVNPYMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKV * * **:*:***:.* ***:::**.:: .: * **:**:*:****: Mflv_1114|M.gilvum_PYR-GCK MSKMGISTLASYTGAQLFQAIGINQQVLDDYFTGLTCPVGGIDLDDIAAD Mvan_5698|M.vanbaalenii_PYR-1 MSKMGISTLASYTGAQLFQAIGISQAVLDEYFAGLSCPVGGIDLDDIADD MSMEG_6459|M.smegmatis_MC2_155 MSKMGISTLASYTGAQLFQAIGISQQVLDEYFTGLSCPVGGIDLEDIAAD TH_2102|M.thermoresistible__bu MSKMGISTLRSYTGAQLFQAIGISQEVLDEYFTGLSCPTGGIDLDDIAAD Mb3889c|M.bovis_AF2122/97 MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD Rv3859c|M.tuberculosis_H37Rv MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD MLBr_00061|M.leprae_Br4923 MSKMGISTLASYVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAE MAV_0166|M.avium_104 MSKMGISTLASYTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAAD MMAR_5413|M.marinum_M MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD MUL_5037|M.ulcerans_Agy99 MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD MAB_0091|M.abscessus_ATCC_1997 MSKMGISTLASYTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAAD ********* **.*******:*:.: :*::**:**:*. *** *::** : Mflv_1114|M.gilvum_PYR-GCK IASRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST Mvan_5698|M.vanbaalenii_PYR-1 VATRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST MSMEG_6459|M.smegmatis_MC2_155 VAARHSLAFLDRPDERAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST TH_2102|M.thermoresistible__bu VARRHELAYLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST Mb3889c|M.bovis_AF2122/97 VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST Rv3859c|M.tuberculosis_H37Rv VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST MLBr_00061|M.leprae_Br4923 VAVRHRVAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT MAV_0166|M.avium_104 VAARHALAYLDRPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT MMAR_5413|M.marinum_M VATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST MUL_5037|M.ulcerans_Agy99 VASRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST MAB_0091|M.abscessus_ATCC_1997 VASRHNLAFLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST :* ** :*:****:* ************************:*******:* Mflv_1114|M.gilvum_PYR-GCK RTGQYSIFKEYTQLVDDQSERMASLRGLLKFRDGERPSVPLDEVEPASEI Mvan_5698|M.vanbaalenii_PYR-1 RTGQYSVFKEYTSLVDDQSERMASLRGLLKFREGVRPPVPLEEVEPASEI MSMEG_6459|M.smegmatis_MC2_155 RTGQYSIFKEYTKLVDDQSERIASLRGLLKFREGHRPPVPIEEVEPASEI TH_2102|M.thermoresistible__bu RTGQYEIFKEYTRLVDDQSERMASLRGLLKFKEGVRPPVPIEEVEPASEI Mb3889c|M.bovis_AF2122/97 RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI Rv3859c|M.tuberculosis_H37Rv RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI MLBr_00061|M.leprae_Br4923 RSGQYKIFKEYTRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEI MAV_0166|M.avium_104 RTGQYKIFKDYTRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEI MMAR_5413|M.marinum_M RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI MUL_5037|M.ulcerans_Agy99 RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI MAB_0091|M.abscessus_ATCC_1997 RTGQYSVFKEYTQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEI *:***.:**:** ********:*********: * *..:*::******** Mflv_1114|M.gilvum_PYR-GCK VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVSRFDRDEN Mvan_5698|M.vanbaalenii_PYR-1 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVTRFDPDEN MSMEG_6459|M.smegmatis_MC2_155 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEAVHRFNPDEN TH_2102|M.thermoresistible__bu VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNSGEGGEHVSRFDPDDN Mb3889c|M.bovis_AF2122/97 VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN Rv3859c|M.tuberculosis_H37Rv VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN MLBr_00061|M.leprae_Br4923 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPN MAV_0166|M.avium_104 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPD MMAR_5413|M.marinum_M VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN MUL_5037|M.ulcerans_Agy99 VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN MAB_0091|M.abscessus_ATCC_1997 VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDEN **********:*******************.***.***** ** * : Mflv_1114|M.gilvum_PYR-GCK GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV Mvan_5698|M.vanbaalenii_PYR-1 GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV MSMEG_6459|M.smegmatis_MC2_155 GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV TH_2102|M.thermoresistible__bu GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGNKV Mb3889c|M.bovis_AF2122/97 GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV Rv3859c|M.tuberculosis_H37Rv GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV MLBr_00061|M.leprae_Br4923 GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGRKV MAV_0166|M.avium_104 GSWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV MMAR_5413|M.marinum_M GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV MUL_5037|M.ulcerans_Agy99 GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV MAB_0091|M.abscessus_ATCC_1997 GDWRRSAIKQVASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGGQLPAHKV *.***********.*********:****:*****************..** Mflv_1114|M.gilvum_PYR-GCK YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK Mvan_5698|M.vanbaalenii_PYR-1 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARIHVK MSMEG_6459|M.smegmatis_MC2_155 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARIHVK TH_2102|M.thermoresistible__bu YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK Mb3889c|M.bovis_AF2122/97 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK Rv3859c|M.tuberculosis_H37Rv YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MLBr_00061|M.leprae_Br4923 YPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MAV_0166|M.avium_104 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARVHVK MMAR_5413|M.marinum_M YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MUL_5037|M.ulcerans_Agy99 YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MAB_0091|M.abscessus_ATCC_1997 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPQARIHVK ***:*:**:*******************************:** **:*** Mflv_1114|M.gilvum_PYR-GCK LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL Mvan_5698|M.vanbaalenii_PYR-1 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MSMEG_6459|M.smegmatis_MC2_155 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL TH_2102|M.thermoresistible__bu LVSEAGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL Mb3889c|M.bovis_AF2122/97 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL Rv3859c|M.tuberculosis_H37Rv LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MLBr_00061|M.leprae_Br4923 LVSENGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSGAPWELGL MAV_0166|M.avium_104 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MMAR_5413|M.marinum_M LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MUL_5037|M.ulcerans_Agy99 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MAB_0091|M.abscessus_ATCC_1997 LVSENGVGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL **** ******:***********:*********:****:**:******** Mflv_1114|M.gilvum_PYR-GCK AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV Mvan_5698|M.vanbaalenii_PYR-1 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV MSMEG_6459|M.smegmatis_MC2_155 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV TH_2102|M.thermoresistible__bu AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV Mb3889c|M.bovis_AF2122/97 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV Rv3859c|M.tuberculosis_H37Rv AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV MLBr_00061|M.leprae_Br4923 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV MAV_0166|M.avium_104 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV MMAR_5413|M.marinum_M AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV MUL_5037|M.ulcerans_Agy99 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV MAB_0091|M.abscessus_ATCC_1997 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGFATAPLVV ******************************::* ***.************ Mflv_1114|M.gilvum_PYR-GCK AGCIMMRVCHLDTCPVGVATQNPVLRKRFNGQPEFVENFFMFIAEEVREL Mvan_5698|M.vanbaalenii_PYR-1 TGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL MSMEG_6459|M.smegmatis_MC2_155 SGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL TH_2102|M.thermoresistible__bu SGCVMMRVCHLDTCPVGVATQNPVLRQRFTGKPEFVENFFLFIAEEVREY Mb3889c|M.bovis_AF2122/97 AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY Rv3859c|M.tuberculosis_H37Rv AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY MLBr_00061|M.leprae_Br4923 AGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFIAEEVREY MAV_0166|M.avium_104 SGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFIAEEVREY MMAR_5413|M.marinum_M AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY MUL_5037|M.ulcerans_Agy99 AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY MAB_0091|M.abscessus_ATCC_1997 SGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFIAEEVREL :**:*******************:**:**.*:********:******** Mflv_1114|M.gilvum_PYR-GCK MAELGFRTVNEMVGQVGALDTTQAAERWKAHKLDLTPVLHEPDSAFMNQD Mvan_5698|M.vanbaalenii_PYR-1 MAQLGFRTVNEMVGQVGALDTTQAAEHWKAHKLDLAPVLHEPESAFMNQD MSMEG_6459|M.smegmatis_MC2_155 MAQLGFRTVNEMVGQVGALDTTKAAEHWKAHKLDLTPVLHEPDSAFMNQD TH_2102|M.thermoresistible__bu MAKMGFRTVNEMVGQVGMLDTTRAAEHWKAHKLDLSPVLHQPESAFMNQD Mb3889c|M.bovis_AF2122/97 LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD Rv3859c|M.tuberculosis_H37Rv LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD MLBr_00061|M.leprae_Br4923 MAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPESAFMNQD MAV_0166|M.avium_104 MAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPESAFMNQD MMAR_5413|M.marinum_M MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQD MUL_5037|M.ulcerans_Agy99 MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQG MAB_0091|M.abscessus_ATCC_1997 MAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPESAFMNQD :*::****.** ***. ** . :*** :** *** :*:******. Mflv_1114|M.gilvum_PYR-GCK LYCSSRQDHGLDKALDQQLITQSREAIDNGTPVRFSTTIANVNRTVGTML Mvan_5698|M.vanbaalenii_PYR-1 LYCSSRQDHGLDKALDQQLIAQCREALDRGTPVRFSTTIANVNRTVGTML MSMEG_6459|M.smegmatis_MC2_155 LYCSSRQDHGLDKALDQQLIVQSREALDSGTPVRFTAKITNVNRTVGTML TH_2102|M.thermoresistible__bu LYCSSRQDHGLDKALDQQLITMCREALDNGTPVRFSTTIANVNRTVGTML Mb3889c|M.bovis_AF2122/97 LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML Rv3859c|M.tuberculosis_H37Rv LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML MLBr_00061|M.leprae_Br4923 LYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGNVNRTVGTML MAV_0166|M.avium_104 LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISNVNRTVGTML MMAR_5413|M.marinum_M LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML MUL_5037|M.ulcerans_Agy99 LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML MAB_0091|M.abscessus_ATCC_1997 LYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITNVNRTVGTML ****. *****:*.******. .*:*:* *.**:* : * ********** Mflv_1114|M.gilvum_PYR-GCK GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFLPKGITLRVYGDANDYV Mvan_5698|M.vanbaalenii_PYR-1 GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV MSMEG_6459|M.smegmatis_MC2_155 GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV TH_2102|M.thermoresistible__bu GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV Mb3889c|M.bovis_AF2122/97 GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV Rv3859c|M.tuberculosis_H37Rv GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV MLBr_00061|M.leprae_Br4923 GHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV MAV_0166|M.avium_104 GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV MMAR_5413|M.marinum_M GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV MUL_5037|M.ulcerans_Agy99 GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV MAB_0091|M.abscessus_ATCC_1997 GHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLRLFGDANDYV ***:*****.:****.:***** **********:*:*****::******* Mflv_1114|M.gilvum_PYR-GCK GKGLSGGRVVVRPSDNAPEGYVAEDNIIAGNVVLFGATSGEMFLRGQVGE Mvan_5698|M.vanbaalenii_PYR-1 GKGLSGGRVVVRPSDGAPEGYAAEGNIIAGNVVLFGATSGQMFLRGQVGE MSMEG_6459|M.smegmatis_MC2_155 GKGLSGGRIVVRPADEAPESFAAEDNIIAGNVVLFGATSGEAFLRGQVGE TH_2102|M.thermoresistible__bu GKGLSGGRIVVRPPDNVPESFVAEDNIIAGNVILFGATSGEVFLRGQVGE Mb3889c|M.bovis_AF2122/97 GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE Rv3859c|M.tuberculosis_H37Rv GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE MLBr_00061|M.leprae_Br4923 GKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGEVYLRGVVGE MAV_0166|M.avium_104 GKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGEAYLRGVVGE MMAR_5413|M.marinum_M GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE MUL_5037|M.ulcerans_Agy99 GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE MAB_0091|M.abscessus_ATCC_1997 GKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGEAFLNGVVGE *******::****. .* .:.** ***.***:*******: :*.* *** Mflv_1114|M.gilvum_PYR-GCK RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGVGYV Mvan_5698|M.vanbaalenii_PYR-1 RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV MSMEG_6459|M.smegmatis_MC2_155 RFAVRNSGAVAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV TH_2102|M.thermoresistible__bu RFAVRNSGALAVVEGVGDHGCEYMTGGRVVILGPVGRNFAAGMSGGIAYV Mb3889c|M.bovis_AF2122/97 RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV Rv3859c|M.tuberculosis_H37Rv RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV MLBr_00061|M.leprae_Br4923 RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAAGMSGGEAYV MAV_0166|M.avium_104 RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAAGMSGGVAYI MMAR_5413|M.marinum_M RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV MUL_5037|M.ulcerans_Agy99 RFAVRNSGAHVVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV MAB_0091|M.abscessus_ATCC_1997 RFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAAGMSGGVAYV ********* .**************** **:** .*********** .*: Mflv_1114|M.gilvum_PYR-GCK YDPQDALAGNLNAEMVELESLGDSDSDDAVFVHGMIQAHVGATDSAVGQR Mvan_5698|M.vanbaalenii_PYR-1 YDPDNTLADNLNAEMVELEGMGGIDSDDAVFVHGIVQEHVDATDSAVGQR MSMEG_6459|M.smegmatis_MC2_155 YDPRAALPKNLNPEMVEIEALEEADT---EWLRGILASHVDATDSAVGQR TH_2102|M.thermoresistible__bu YDPDGVLPGRLNREMVELESLDDEDR---EWLRGFIAAHVDATDSAIGQR Mb3889c|M.bovis_AF2122/97 YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR Rv3859c|M.tuberculosis_H37Rv YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR MLBr_00061|M.leprae_Br4923 YDSDGELPANLNFEMVELEPLDFDDA---AWLYATIQAHVDATDSAVGQR MAV_0166|M.avium_104 YDPPGEFPQHLNAEMVELESLDDDDI---EWLHGMIQAHVDATDSAVGQR MMAR_5413|M.marinum_M YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR MUL_5037|M.ulcerans_Agy99 YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR MAB_0091|M.abscessus_ATCC_1997 YDPDKRLMDNLNDEMVDLDALDPDDQ---QVLRSLIEKHVAATDSAVGQR **. : .** ***::: : * : . : ** *****:*** Mflv_1114|M.gilvum_PYR-GCK ILADWSGEQVHFKKVMPRDYKRVLEAIAEAERAGADENGVAEAIMAAANG Mvan_5698|M.vanbaalenii_PYR-1 ILADWNTELGHFKKVMPRDFKRVLQAIAEAQQSGADENGVAEAIMAAANG MSMEG_6459|M.smegmatis_MC2_155 ILADWDNELKHFAKVMPRDYKRVLAAIAEAEAKGLTGSDIDDAIMAASNG TH_2102|M.thermoresistible__bu ILNDWDEHVTHFAKVMPRDYKRVLTAIAEAEASGAD---VDEAIMAAANG Mb3889c|M.bovis_AF2122/97 ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG Rv3859c|M.tuberculosis_H37Rv ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG MLBr_00061|M.leprae_Br4923 ILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVD---VNKVIMEPAHG MAV_0166|M.avium_104 ILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGD---VDKAIMAAAHG MMAR_5413|M.marinum_M VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG MUL_5037|M.ulcerans_Agy99 VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG MAB_0091|M.abscessus_ATCC_1997 ILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGD---VNEAIMAAARG :* .* . * ****:*::*** *** *: * : ..** .:.*