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M. smegmatis MC2 155 MSMEG_6459 (-)

annotation: ferredoxin-dependent glutamate synthase 1
coordinates: 6522132 - 6526760
length: 1542

GMTPSSFGGSGRSSRDNRGLYNPAYEHDACGVAMVADMHGRRSRDIVDKAITALVNLEHRGAQGAEPNTG
DGAGILIQVPDAFLRAVVDFDLPEPGSYATGMAFLPQSSRDAAAACESVEKIAEAEGLEVLGWREVPTDD
SSLGALARDAMPTFRQLFLGGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRETVYFPSLSGQTFVYK
GMLTTPQLKQFYLDLQDERLESALGIVHSRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREAL
IRTDVFGSDGLDKIVPVCTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHEDMDPARRAFYEY
HASLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLPLDPAKVVKKMRLQPGR
MFLVDTAQGRIVDDEEVKAELAAAEPYQEWLEQGLFHLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNL
LVAPMARTGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREEVVTSLQGTVGPEGDLL
NPGPESCRQIVLPQPILRNADLSKLICVDPDHEIRGHKHGMRAAVIRCLYPVNRGGVGLKEALDNVRAKV
SEAIREGARIIVLSDRESNETMAPIPSLLSVAAVHHHLVRERTRTKVGLVVEAGDAREVHHMATLVGFGA
AAINPYMAFESIEDMVDRGVITGLTSDQAKANYVKAAGKGVLKVMSKMGISTLASYTGAQLFQAIGISQQ
VLDEYFTGLSCPVGGIDLEDIAADVAARHSLAFLDRPDERAHRELEVGGEYQWRREGEYHLFNPDTVFKL
QHSTRTGQYSIFKEYTKLVDDQSERIASLRGLLKFREGHRPPVPIEEVEPASEIVKRFSTGAMSYGSISA
EAHETLAIAMNRLGGRSNSGEGGEAVHRFNPDENGDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQG
AKPGEGGQLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARIHVKLVSENG
VGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGLAETQQTLLLNGLRDRIVVQVDGQLKT
GRDVVIAALLGAEEFGFATAPLVVSGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEE
VRELMAQLGFRTVNEMVGQVGALDTTKAAEHWKAHKLDLTPVLHEPDSAFMNQDLYCSSRQDHGLDKALD
QQLIVQSREALDSGTPVRFTAKITNVNRTVGTMLGHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPK
GITLRVYGDANDYVGKGLSGGRIVVRPADEAPESFAAEDNIIAGNVVLFGATSGEAFLRGQVGERFAVRN
SGAVAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYVYDPRAALPKNLNPEMVEIEALEEADT
EWLRGILASHVDATDSAVGQRILADWDNELKHFAKVMPRDYKRVLAAIAEAEAKGLTGSDIDDAIMAASN
G*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6459--100% (1542)ferredoxin-dependent glutamate synthase 1
M. smegmatis MC2 155MSMEG_3225-0.063.62% (1542) ferredoxin-dependent glutamate synthase 1
M. smegmatis MC2 155MSMEG_5594-1e-3334.07% (270) ferredoxin-dependent glutamate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3889cgltB0.084.91% (1524) putative ferredoxin-dependent glutamate synthase
M. gilvum PYR-GCKMflv_1114-0.089.59% (1528) glutamate synthase (ferredoxin)
M. tuberculosis H37RvRv3859cgltB0.084.91% (1524) ferredoxin-dependent glutamate synthase
M. leprae Br4923MLBr_00061gltB0.082.09% (1524) putative ferredoxin-dependent glutamate synthase
M. abscessus ATCC 19977MAB_0091-0.082.20% (1528) putative ferredoxin-dependent glutamate synthase
M. marinum MMMAR_5413gltB0.084.45% (1524) ferredoxin-dependent glutamate synthase
M. avium 104MAV_0166-0.085.17% (1524) ferredoxin-dependent glutamate synthase 1
M. thermoresistible (build 8)TH_2102gltB0.088.15% (1528) PROBABLE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE
M. ulcerans Agy99MUL_5037gltB0.084.12% (1524) ferredoxin-dependent glutamate synthase
M. vanbaalenii PYR-1Mvan_5698-0.090.49% (1514) glutamate synthase (ferredoxin)

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1114|M.gilvum_PYR-GCK          -------------MAPSRQGLYDPAFEHDSCGVAMVADIHGRRSRDIVEK
Mvan_5698|M.vanbaalenii_PYR-1       ----------------------------------MVADMHGRRSRDIVDK
MSMEG_6459|M.smegmatis_MC2_155      MGMTPSSFGGSGRSSRDNRGLYNPAYEHDACGVAMVADMHGRRSRDIVDK
TH_2102|M.thermoresistible__bu      -------------MTPKAQGLYNPAFEHDACGVAMVADMYGRRSRDIVDK
Mb3889c|M.bovis_AF2122/97           -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK
Rv3859c|M.tuberculosis_H37Rv        -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK
MLBr_00061|M.leprae_Br4923          -------------MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDK
MAV_0166|M.avium_104                -----------MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDK
MMAR_5413|M.marinum_M               -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK
MUL_5037|M.ulcerans_Agy99           -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK
MAB_0091|M.abscessus_ATCC_1997      -------------MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDK
                                                                      **.*::***:****:*

Mflv_1114|M.gilvum_PYR-GCK          AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVC----GFDLPEP
Mvan_5698|M.vanbaalenii_PYR-1       AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVCEKE-GFDLPEA
MSMEG_6459|M.smegmatis_MC2_155      AITALVNLEHRGAQGAEPNTGDGAGILIQVPDAFLRAVV----DFDLPEP
TH_2102|M.thermoresistible__bu      AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFLRAVVEEQGDFELPPP
Mb3889c|M.bovis_AF2122/97           AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP
Rv3859c|M.tuberculosis_H37Rv        AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP
MLBr_00061|M.leprae_Br4923          AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLRAVV----DFELPAA
MAV_0166|M.avium_104                AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLREVV----DFELPPE
MMAR_5413|M.marinum_M               AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP
MUL_5037|M.ulcerans_Agy99           AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP
MAB_0091|M.abscessus_ATCC_1997      AITALLNLEHRGAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAE
                                    *****:******* ****.:******::*:** *:* .     .*:**  

Mflv_1114|M.gilvum_PYR-GCK          GSFATGIAFLPQSAKDAATACESVEKIAEAEGLRVLGWRDVPTDDSSLGA
Mvan_5698|M.vanbaalenii_PYR-1       GSYATGMAFLPQSSKDAAIACAAVEKIAEAEGLQVLGWRDVPTDDSSLGA
MSMEG_6459|M.smegmatis_MC2_155      GSYATGMAFLPQSSRDAAAACESVEKIAEAEGLEVLGWREVPTDDSSLGA
TH_2102|M.thermoresistible__bu      GSYATGIAFLPQSAKDAAQACDAVEKIVEAEGLTVLGWREVPIDDSSLGA
Mb3889c|M.bovis_AF2122/97           GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA
Rv3859c|M.tuberculosis_H37Rv        GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA
MLBr_00061|M.leprae_Br4923          SSYATGIAFLPQSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGA
MAV_0166|M.avium_104                GSYATGIAFLPQSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGA
MMAR_5413|M.marinum_M               GSYATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTDDSSLGA
MUL_5037|M.ulcerans_Agy99           GSYATGIAFLPQSSKDAAAACAAVEKIGEAEGLQVLGWRNVPTDDSSLGA
MAB_0091|M.abscessus_ATCC_1997      GSYASGIAFLPQGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGA
                                    .*:*:*:*****.::*** ** :*:**  **** *****.** * *****

Mflv_1114|M.gilvum_PYR-GCK          LARDAMPTFRQVFMAGAEGMDLERRAYVVRKRAEHELGTKGPGQDGPGRE
Mvan_5698|M.vanbaalenii_PYR-1       LARDAMPTFRQIFLAGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE
MSMEG_6459|M.smegmatis_MC2_155      LARDAMPTFRQLFLGGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE
TH_2102|M.thermoresistible__bu      LARDAMPTFRQLFLGGATGIDLERRAYVVRKRAEHELGTKGPGQDGPGRE
Mb3889c|M.bovis_AF2122/97           LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE
Rv3859c|M.tuberculosis_H37Rv        LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE
MLBr_00061|M.leprae_Br4923          LSRDAMPTFRQVFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRE
MAV_0166|M.avium_104                LSRDAMPTFRQVFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRE
MMAR_5413|M.marinum_M               LSRDAMPTFRQVFLAGASDMTLERRCYVIRKRAEHELGTKGPGQDGPGRE
MUL_5037|M.ulcerans_Agy99           LSRDAMPTFRQVFLAGASDMALERRCYVIRKRAEHELGTKGPGQDGPGRE
MAB_0091|M.abscessus_ATCC_1997      LARDAMPTFRQLFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEE
                                    *:*********:*:.** .: **** *::*** *****.:*.*:.. *.*

Mflv_1114|M.gilvum_PYR-GCK          TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT
Mvan_5698|M.vanbaalenii_PYR-1       TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT
MSMEG_6459|M.smegmatis_MC2_155      TVYFPSLSGQTFVYKGMLTTPQLKQFYLDLQDERLESALGIVHSRFSTNT
TH_2102|M.thermoresistible__bu      TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERLTSALAIVHSRFSTNT
Mb3889c|M.bovis_AF2122/97           TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT
Rv3859c|M.tuberculosis_H37Rv        TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT
MLBr_00061|M.leprae_Br4923          TIYFPSLSSQTFVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNT
MAV_0166|M.avium_104                TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT
MMAR_5413|M.marinum_M               TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT
MUL_5037|M.ulcerans_Agy99           TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT
MAB_0091|M.abscessus_ATCC_1997      TVYFPSLSGRTFVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNT
                                    *:******.:*:***********: ** ****:*: ***.**********

Mflv_1114|M.gilvum_PYR-GCK          FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDVFGAKADLDKI
Mvan_5698|M.vanbaalenii_PYR-1       FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDIFGGQ-DLEKV
MSMEG_6459|M.smegmatis_MC2_155      FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDVFGSD-GLDKI
TH_2102|M.thermoresistible__bu      FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDLFGGQ-DLEKV
Mb3889c|M.bovis_AF2122/97           FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL
Rv3859c|M.tuberculosis_H37Rv        FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL
MLBr_00061|M.leprae_Br4923          FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKL
MAV_0166|M.avium_104                FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKL
MMAR_5413|M.marinum_M               FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL
MUL_5037|M.ulcerans_Agy99           FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL
MAB_0091|M.abscessus_ATCC_1997      FPSWPLAHPYRRVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKI
                                    *********:**:*********:************::**:**    ::*:

Mflv_1114|M.gilvum_PYR-GCK          TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR
Mvan_5698|M.vanbaalenii_PYR-1       TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR
MSMEG_6459|M.smegmatis_MC2_155      VPVCTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHEDMDPAR
TH_2102|M.thermoresistible__bu      APICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWEQHESMDPAR
Mb3889c|M.bovis_AF2122/97           FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR
Rv3859c|M.tuberculosis_H37Rv        FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR
MLBr_00061|M.leprae_Br4923          FPICTPGASDTARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPAR
MAV_0166|M.avium_104                FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR
MMAR_5413|M.marinum_M               FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR
MUL_5037|M.ulcerans_Agy99           FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR
MAB_0091|M.abscessus_ATCC_1997      FPICTRGASDTARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAEL
                                     *:** **********.*********.* ************:* .*..  

Mflv_1114|M.gilvum_PYR-GCK          RAFYEFHDSLMEPWDGPAAVCFTDGTVIGAVLDRNGLRPSRIWVTEDGLV
Mvan_5698|M.vanbaalenii_PYR-1       RAFYQYHASLMEPWDGPAAVCFTDGTVVGAVLDRNGLRPSRIWVTSDGLV
MSMEG_6459|M.smegmatis_MC2_155      RAFYEYHASLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTDDGLV
TH_2102|M.thermoresistible__bu      RAFYEFHDSLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTADGLV
Mb3889c|M.bovis_AF2122/97           RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV
Rv3859c|M.tuberculosis_H37Rv        RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV
MLBr_00061|M.leprae_Br4923          RAFYQYHASLMEPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLV
MAV_0166|M.avium_104                RAFYQYHASLMEPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLV
MMAR_5413|M.marinum_M               RAFYQYHSSLMEPWDGPASMTFTDGTIIGAVLDRNGLRPSRIWVTEDGLV
MUL_5037|M.ulcerans_Agy99           RAFYQYHSSLMEPWDGPASMTFTDGTMVGAVLDRNGLRPSRIWVTEDGLV
MAB_0091|M.abscessus_ATCC_1997      RSFYEFHASLMEPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLV
                                    *:**::* **********:: ****.::*************:*:*  ***

Mflv_1114|M.gilvum_PYR-GCK          VMASEAGVLDLDPSTVVKKMRLQPGRMFLVDTAQGRIVDDEEIKAQLAAE
Mvan_5698|M.vanbaalenii_PYR-1       VMASEAGVLDLDPGTVVQKMRLQPGRMFLVDTAQGRIVSDEEIKAELAAG
MSMEG_6459|M.smegmatis_MC2_155      VMASEAGVLPLDPAKVVKKMRLQPGRMFLVDTAQGRIVDDEEVKAELAAA
TH_2102|M.thermoresistible__bu      VMASEAGVLNLDPATVVRKMRLQPGRMFLVDTAQGRIIDDEEIKAELAAE
Mb3889c|M.bovis_AF2122/97           VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE
Rv3859c|M.tuberculosis_H37Rv        VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE
MLBr_00061|M.leprae_Br4923          VMASEAGVLDLDPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAE
MAV_0166|M.avium_104                VMASEAGVLDLDPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE
MMAR_5413|M.marinum_M               VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE
MUL_5037|M.ulcerans_Agy99           VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEAIKAELAAE
MAB_0091|M.abscessus_ATCC_1997      VMASEAGVLDLDPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAA
                                    ********* *.*. **:: ************:****:.** :**.*** 

Mflv_1114|M.gilvum_PYR-GCK          HPYQEWLDAGLFQLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP
Mvan_5698|M.vanbaalenii_PYR-1       QPYQEWLDAGLFHLDELPQGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP
MSMEG_6459|M.smegmatis_MC2_155      EPYQEWLEQGLFHLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP
TH_2102|M.thermoresistible__bu      HPYQEWLDAGLFPLDELPQGDYQRMPHHRVVLRQRVFGYTSEELNLIVGP
Mb3889c|M.bovis_AF2122/97           HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP
Rv3859c|M.tuberculosis_H37Rv        HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP
MLBr_00061|M.leprae_Br4923          HPYQEWLDKGLVPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAP
MAV_0166|M.avium_104                HPYQEWLDRNLVPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAP
MMAR_5413|M.marinum_M               HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP
MUL_5037|M.ulcerans_Agy99           HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP
MAB_0091|M.abscessus_ATCC_1997      EPYQRWLEEGLVRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAP
                                    .***.**: .*. ::.**     :*.*.*:* **  **** **:**:*.*

Mflv_1114|M.gilvum_PYR-GCK          MARNGAEALGSMGTDTPIAVLSSRPRMLYDYFQQLFAQVTNPPLDAIREE
Mvan_5698|M.vanbaalenii_PYR-1       MARSGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE
MSMEG_6459|M.smegmatis_MC2_155      MARTGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE
TH_2102|M.thermoresistible__bu      MARTGAEPLGSMGTDTPIAVLSQRSRLLFDYFQQMFAQVTNPPLDAIREE
Mb3889c|M.bovis_AF2122/97           MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE
Rv3859c|M.tuberculosis_H37Rv        MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE
MLBr_00061|M.leprae_Br4923          MVRAGSEPIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREE
MAV_0166|M.avium_104                MVRTGAEPIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREE
MMAR_5413|M.marinum_M               MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE
MUL_5037|M.ulcerans_Agy99           MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE
MAB_0091|M.abscessus_ATCC_1997      MARTGAEALGSMGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREE
                                    *.* *:*.:****:***:**** *.*:*:***:*:***************

Mflv_1114|M.gilvum_PYR-GCK          VVTSLQGAMGPEGDLLNPGPESCRQIVLPQPILRNAELSKLICVDPDHEI
Mvan_5698|M.vanbaalenii_PYR-1       VVTSLQGTVGPEGDLLNPDAESCRQIVLPNPILRNAELSKLICVDPDHEI
MSMEG_6459|M.smegmatis_MC2_155      VVTSLQGTVGPEGDLLNPGPESCRQIVLPQPILRNADLSKLICVDPDHEI
TH_2102|M.thermoresistible__bu      VITSLQGVIGPEGDLLNPGPESCRQIVLPQPILRNHELAKLINVDPDHEV
Mb3889c|M.bovis_AF2122/97           VVTSLQGTTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKV
Rv3859c|M.tuberculosis_H37Rv        VVTSLQGTTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKV
MLBr_00061|M.leprae_Br4923          VVTSLQGTTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEV
MAV_0166|M.avium_104                VVTSLQGTTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEV
MMAR_5413|M.marinum_M               VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI
MUL_5037|M.ulcerans_Agy99           VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI
MAB_0091|M.abscessus_ATCC_1997      VVTSLGGVIGPEGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTV
                                    *:*** *. * * *** *   **:** *.:*:*:* :* **: ::*   :

Mflv_1114|M.gilvum_PYR-GCK          RGHKHGMRAAVIRCLYPVNRGGQGLKEALDNVRAKVSSAIRDGARIIVLS
Mvan_5698|M.vanbaalenii_PYR-1       RGHKHGMRAAVIRCLYPVNRGGRGLKEALDNVRAKVSAAIRDGARIIVLS
MSMEG_6459|M.smegmatis_MC2_155      RGHKHGMRAAVIRCLYPVNRGGVGLKEALDNVRAKVSEAIREGARIIVLS
TH_2102|M.thermoresistible__bu      RGRKHGMRAAVVRCLFPVNRGGQGLKEALDRVRAKVSAAIREGARIIVLS
Mb3889c|M.bovis_AF2122/97           NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS
Rv3859c|M.tuberculosis_H37Rv        NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS
MLBr_00061|M.leprae_Br4923          NGRPHGMRSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILS
MAV_0166|M.avium_104                NGRPHGMRSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILS
MMAR_5413|M.marinum_M               NGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADGARIIVLS
MUL_5037|M.ulcerans_Agy99           NGRPHGLKSKVVRCLYPVAEGGSGLAAALNEVRAQASAAIADGARIIVLS
MAB_0091|M.abscessus_ATCC_1997      NGRAHGFSSRVIRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILS
                                    .*: **: : *: **: *  .* **  **  **. .: **  **::*:**

Mflv_1114|M.gilvum_PYR-GCK          DRESDEQMAPIPSLLSVSAVHHHLVRERTRTQVGLIVEAGDAREVHHMAA
Mvan_5698|M.vanbaalenii_PYR-1       DRESNEQMAPIPSLLSVSAVHHHLVRDRTRTKVGLVVEAGDAREVHHMAA
MSMEG_6459|M.smegmatis_MC2_155      DRESNETMAPIPSLLSVAAVHHHLVRERTRTKVGLVVEAGDAREVHHMAT
TH_2102|M.thermoresistible__bu      DRESDEQLAPIPSLLSVAAVHHHLVRDRTRTQVGLVVEAGDAREVHHMAA
Mb3889c|M.bovis_AF2122/97           DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA
Rv3859c|M.tuberculosis_H37Rv        DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA
MLBr_00061|M.leprae_Br4923          DRNSDEQMAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAA
MAV_0166|M.avium_104                DRESDEKMAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAA
MMAR_5413|M.marinum_M               DRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAREVHHMAM
MUL_5037|M.ulcerans_Agy99           DRESDERMAPIPALLAVAGVHHHLVRERTRTKVGLVVESGDAREVHHMAM
MAB_0091|M.abscessus_ATCC_1997      DRESDDLMAPIPSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAA
                                    **:*:: :****:**:*:.*******:*:**:***:**:********:* 

Mflv_1114|M.gilvum_PYR-GCK          LCGFGAAAINPYMAFESIEDMVDRGVITDITSDQAKANYVKAAGKGVLKV
Mvan_5698|M.vanbaalenii_PYR-1       LCGFGAAAINPYMAFESIEDMVDRGVISGISSDQAKANYVKAAGKGVLKV
MSMEG_6459|M.smegmatis_MC2_155      LVGFGAAAINPYMAFESIEDMVDRGVITGLTSDQAKANYVKAAGKGVLKV
TH_2102|M.thermoresistible__bu      LIGFGASAINPYLAFESIEDMLDRNLLEGLDRETALNNYIKAAGKGVLKV
Mb3889c|M.bovis_AF2122/97           LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV
Rv3859c|M.tuberculosis_H37Rv        LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV
MLBr_00061|M.leprae_Br4923          LIGFGAAAVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKI
MAV_0166|M.avium_104                LVGFGAAAINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKV
MMAR_5413|M.marinum_M               LLGCGAAAVNPYLAFESIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV
MUL_5037|M.ulcerans_Agy99           LLGCGAAAVNPYLAFASIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV
MAB_0091|M.abscessus_ATCC_1997      LVGFGAAAVNPYMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKV
                                    * * **:*:***:.* ***:::**.:: .:    *  **:**:*:****:

Mflv_1114|M.gilvum_PYR-GCK          MSKMGISTLASYTGAQLFQAIGINQQVLDDYFTGLTCPVGGIDLDDIAAD
Mvan_5698|M.vanbaalenii_PYR-1       MSKMGISTLASYTGAQLFQAIGISQAVLDEYFAGLSCPVGGIDLDDIADD
MSMEG_6459|M.smegmatis_MC2_155      MSKMGISTLASYTGAQLFQAIGISQQVLDEYFTGLSCPVGGIDLEDIAAD
TH_2102|M.thermoresistible__bu      MSKMGISTLRSYTGAQLFQAIGISQEVLDEYFTGLSCPTGGIDLDDIAAD
Mb3889c|M.bovis_AF2122/97           MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD
Rv3859c|M.tuberculosis_H37Rv        MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD
MLBr_00061|M.leprae_Br4923          MSKMGISTLASYVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAE
MAV_0166|M.avium_104                MSKMGISTLASYTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAAD
MMAR_5413|M.marinum_M               MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD
MUL_5037|M.ulcerans_Agy99           MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD
MAB_0091|M.abscessus_ATCC_1997      MSKMGISTLASYTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAAD
                                    ********* **.*******:*:.: :*::**:**:*. *** *::** :

Mflv_1114|M.gilvum_PYR-GCK          IASRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST
Mvan_5698|M.vanbaalenii_PYR-1       VATRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST
MSMEG_6459|M.smegmatis_MC2_155      VAARHSLAFLDRPDERAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST
TH_2102|M.thermoresistible__bu      VARRHELAYLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST
Mb3889c|M.bovis_AF2122/97           VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST
Rv3859c|M.tuberculosis_H37Rv        VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST
MLBr_00061|M.leprae_Br4923          VAVRHRVAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT
MAV_0166|M.avium_104                VAARHALAYLDRPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT
MMAR_5413|M.marinum_M               VATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST
MUL_5037|M.ulcerans_Agy99           VASRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST
MAB_0091|M.abscessus_ATCC_1997      VASRHNLAFLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST
                                    :* ** :*:****:* ************************:*******:*

Mflv_1114|M.gilvum_PYR-GCK          RTGQYSIFKEYTQLVDDQSERMASLRGLLKFRDGERPSVPLDEVEPASEI
Mvan_5698|M.vanbaalenii_PYR-1       RTGQYSVFKEYTSLVDDQSERMASLRGLLKFREGVRPPVPLEEVEPASEI
MSMEG_6459|M.smegmatis_MC2_155      RTGQYSIFKEYTKLVDDQSERIASLRGLLKFREGHRPPVPIEEVEPASEI
TH_2102|M.thermoresistible__bu      RTGQYEIFKEYTRLVDDQSERMASLRGLLKFKEGVRPPVPIEEVEPASEI
Mb3889c|M.bovis_AF2122/97           RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI
Rv3859c|M.tuberculosis_H37Rv        RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI
MLBr_00061|M.leprae_Br4923          RSGQYKIFKEYTRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEI
MAV_0166|M.avium_104                RTGQYKIFKDYTRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEI
MMAR_5413|M.marinum_M               RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI
MUL_5037|M.ulcerans_Agy99           RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI
MAB_0091|M.abscessus_ATCC_1997      RTGQYSVFKEYTQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEI
                                    *:***.:**:** ********:*********: * *..:*::********

Mflv_1114|M.gilvum_PYR-GCK          VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVSRFDRDEN
Mvan_5698|M.vanbaalenii_PYR-1       VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVTRFDPDEN
MSMEG_6459|M.smegmatis_MC2_155      VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEAVHRFNPDEN
TH_2102|M.thermoresistible__bu      VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNSGEGGEHVSRFDPDDN
Mb3889c|M.bovis_AF2122/97           VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN
Rv3859c|M.tuberculosis_H37Rv        VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN
MLBr_00061|M.leprae_Br4923          VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPN
MAV_0166|M.avium_104                VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPD
MMAR_5413|M.marinum_M               VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN
MUL_5037|M.ulcerans_Agy99           VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN
MAB_0091|M.abscessus_ATCC_1997      VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDEN
                                    **********:*******************.***.*****   **  * :

Mflv_1114|M.gilvum_PYR-GCK          GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV
Mvan_5698|M.vanbaalenii_PYR-1       GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV
MSMEG_6459|M.smegmatis_MC2_155      GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV
TH_2102|M.thermoresistible__bu      GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGNKV
Mb3889c|M.bovis_AF2122/97           GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV
Rv3859c|M.tuberculosis_H37Rv        GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV
MLBr_00061|M.leprae_Br4923          GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGRKV
MAV_0166|M.avium_104                GSWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV
MMAR_5413|M.marinum_M               GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV
MUL_5037|M.ulcerans_Agy99           GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV
MAB_0091|M.abscessus_ATCC_1997      GDWRRSAIKQVASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGGQLPAHKV
                                    *.***********.*********:****:*****************..**

Mflv_1114|M.gilvum_PYR-GCK          YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK
Mvan_5698|M.vanbaalenii_PYR-1       YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARIHVK
MSMEG_6459|M.smegmatis_MC2_155      YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARIHVK
TH_2102|M.thermoresistible__bu      YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK
Mb3889c|M.bovis_AF2122/97           YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK
Rv3859c|M.tuberculosis_H37Rv        YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK
MLBr_00061|M.leprae_Br4923          YPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK
MAV_0166|M.avium_104                YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARVHVK
MMAR_5413|M.marinum_M               YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK
MUL_5037|M.ulcerans_Agy99           YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK
MAB_0091|M.abscessus_ATCC_1997      YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPQARIHVK
                                    ***:*:**:*******************************:** **:***

Mflv_1114|M.gilvum_PYR-GCK          LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
Mvan_5698|M.vanbaalenii_PYR-1       LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
MSMEG_6459|M.smegmatis_MC2_155      LVSENGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL
TH_2102|M.thermoresistible__bu      LVSEAGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL
Mb3889c|M.bovis_AF2122/97           LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
Rv3859c|M.tuberculosis_H37Rv        LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
MLBr_00061|M.leprae_Br4923          LVSENGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSGAPWELGL
MAV_0166|M.avium_104                LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
MMAR_5413|M.marinum_M               LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
MUL_5037|M.ulcerans_Agy99           LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
MAB_0091|M.abscessus_ATCC_1997      LVSENGVGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL
                                    **** ******:***********:*********:****:**:********

Mflv_1114|M.gilvum_PYR-GCK          AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV
Mvan_5698|M.vanbaalenii_PYR-1       AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV
MSMEG_6459|M.smegmatis_MC2_155      AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV
TH_2102|M.thermoresistible__bu      AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV
Mb3889c|M.bovis_AF2122/97           AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV
Rv3859c|M.tuberculosis_H37Rv        AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV
MLBr_00061|M.leprae_Br4923          AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV
MAV_0166|M.avium_104                AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV
MMAR_5413|M.marinum_M               AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV
MUL_5037|M.ulcerans_Agy99           AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV
MAB_0091|M.abscessus_ATCC_1997      AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGFATAPLVV
                                    ******************************::* ***.************

Mflv_1114|M.gilvum_PYR-GCK          AGCIMMRVCHLDTCPVGVATQNPVLRKRFNGQPEFVENFFMFIAEEVREL
Mvan_5698|M.vanbaalenii_PYR-1       TGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL
MSMEG_6459|M.smegmatis_MC2_155      SGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL
TH_2102|M.thermoresistible__bu      SGCVMMRVCHLDTCPVGVATQNPVLRQRFTGKPEFVENFFLFIAEEVREY
Mb3889c|M.bovis_AF2122/97           AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY
Rv3859c|M.tuberculosis_H37Rv        AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY
MLBr_00061|M.leprae_Br4923          AGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFIAEEVREY
MAV_0166|M.avium_104                SGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFIAEEVREY
MMAR_5413|M.marinum_M               AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY
MUL_5037|M.ulcerans_Agy99           AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY
MAB_0091|M.abscessus_ATCC_1997      SGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFIAEEVREL
                                    :**:*******************:**:**.*:********:******** 

Mflv_1114|M.gilvum_PYR-GCK          MAELGFRTVNEMVGQVGALDTTQAAERWKAHKLDLTPVLHEPDSAFMNQD
Mvan_5698|M.vanbaalenii_PYR-1       MAQLGFRTVNEMVGQVGALDTTQAAEHWKAHKLDLAPVLHEPESAFMNQD
MSMEG_6459|M.smegmatis_MC2_155      MAQLGFRTVNEMVGQVGALDTTKAAEHWKAHKLDLTPVLHEPDSAFMNQD
TH_2102|M.thermoresistible__bu      MAKMGFRTVNEMVGQVGMLDTTRAAEHWKAHKLDLSPVLHQPESAFMNQD
Mb3889c|M.bovis_AF2122/97           LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD
Rv3859c|M.tuberculosis_H37Rv        LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD
MLBr_00061|M.leprae_Br4923          MAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPESAFMNQD
MAV_0166|M.avium_104                MAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPESAFMNQD
MMAR_5413|M.marinum_M               MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQD
MUL_5037|M.ulcerans_Agy99           MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQG
MAB_0091|M.abscessus_ATCC_1997      MAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPESAFMNQD
                                    :*::****.** ***.  **   .  :***  :** *** :*:******.

Mflv_1114|M.gilvum_PYR-GCK          LYCSSRQDHGLDKALDQQLITQSREAIDNGTPVRFSTTIANVNRTVGTML
Mvan_5698|M.vanbaalenii_PYR-1       LYCSSRQDHGLDKALDQQLIAQCREALDRGTPVRFSTTIANVNRTVGTML
MSMEG_6459|M.smegmatis_MC2_155      LYCSSRQDHGLDKALDQQLIVQSREALDSGTPVRFTAKITNVNRTVGTML
TH_2102|M.thermoresistible__bu      LYCSSRQDHGLDKALDQQLITMCREALDNGTPVRFSTTIANVNRTVGTML
Mb3889c|M.bovis_AF2122/97           LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML
Rv3859c|M.tuberculosis_H37Rv        LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML
MLBr_00061|M.leprae_Br4923          LYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGNVNRTVGTML
MAV_0166|M.avium_104                LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISNVNRTVGTML
MMAR_5413|M.marinum_M               LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML
MUL_5037|M.ulcerans_Agy99           LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML
MAB_0091|M.abscessus_ATCC_1997      LYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITNVNRTVGTML
                                    ****. *****:*.******. .*:*:* *.**:* : * **********

Mflv_1114|M.gilvum_PYR-GCK          GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFLPKGITLRVYGDANDYV
Mvan_5698|M.vanbaalenii_PYR-1       GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV
MSMEG_6459|M.smegmatis_MC2_155      GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV
TH_2102|M.thermoresistible__bu      GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV
Mb3889c|M.bovis_AF2122/97           GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV
Rv3859c|M.tuberculosis_H37Rv        GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV
MLBr_00061|M.leprae_Br4923          GHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV
MAV_0166|M.avium_104                GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV
MMAR_5413|M.marinum_M               GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV
MUL_5037|M.ulcerans_Agy99           GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV
MAB_0091|M.abscessus_ATCC_1997      GHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLRLFGDANDYV
                                    ***:*****.:****.:***** **********:*:*****::*******

Mflv_1114|M.gilvum_PYR-GCK          GKGLSGGRVVVRPSDNAPEGYVAEDNIIAGNVVLFGATSGEMFLRGQVGE
Mvan_5698|M.vanbaalenii_PYR-1       GKGLSGGRVVVRPSDGAPEGYAAEGNIIAGNVVLFGATSGQMFLRGQVGE
MSMEG_6459|M.smegmatis_MC2_155      GKGLSGGRIVVRPADEAPESFAAEDNIIAGNVVLFGATSGEAFLRGQVGE
TH_2102|M.thermoresistible__bu      GKGLSGGRIVVRPPDNVPESFVAEDNIIAGNVILFGATSGEVFLRGQVGE
Mb3889c|M.bovis_AF2122/97           GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE
Rv3859c|M.tuberculosis_H37Rv        GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE
MLBr_00061|M.leprae_Br4923          GKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGEVYLRGVVGE
MAV_0166|M.avium_104                GKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGEAYLRGVVGE
MMAR_5413|M.marinum_M               GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE
MUL_5037|M.ulcerans_Agy99           GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE
MAB_0091|M.abscessus_ATCC_1997      GKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGEAFLNGVVGE
                                    *******::****.  .* .:.** ***.***:*******: :*.* ***

Mflv_1114|M.gilvum_PYR-GCK          RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGVGYV
Mvan_5698|M.vanbaalenii_PYR-1       RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV
MSMEG_6459|M.smegmatis_MC2_155      RFAVRNSGAVAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV
TH_2102|M.thermoresistible__bu      RFAVRNSGALAVVEGVGDHGCEYMTGGRVVILGPVGRNFAAGMSGGIAYV
Mb3889c|M.bovis_AF2122/97           RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV
Rv3859c|M.tuberculosis_H37Rv        RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV
MLBr_00061|M.leprae_Br4923          RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAAGMSGGEAYV
MAV_0166|M.avium_104                RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAAGMSGGVAYI
MMAR_5413|M.marinum_M               RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV
MUL_5037|M.ulcerans_Agy99           RFAVRNSGAHVVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV
MAB_0091|M.abscessus_ATCC_1997      RFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAAGMSGGVAYV
                                    ********* .**************** **:** .*********** .*:

Mflv_1114|M.gilvum_PYR-GCK          YDPQDALAGNLNAEMVELESLGDSDSDDAVFVHGMIQAHVGATDSAVGQR
Mvan_5698|M.vanbaalenii_PYR-1       YDPDNTLADNLNAEMVELEGMGGIDSDDAVFVHGIVQEHVDATDSAVGQR
MSMEG_6459|M.smegmatis_MC2_155      YDPRAALPKNLNPEMVEIEALEEADT---EWLRGILASHVDATDSAVGQR
TH_2102|M.thermoresistible__bu      YDPDGVLPGRLNREMVELESLDDEDR---EWLRGFIAAHVDATDSAIGQR
Mb3889c|M.bovis_AF2122/97           YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR
Rv3859c|M.tuberculosis_H37Rv        YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR
MLBr_00061|M.leprae_Br4923          YDSDGELPANLNFEMVELEPLDFDDA---AWLYATIQAHVDATDSAVGQR
MAV_0166|M.avium_104                YDPPGEFPQHLNAEMVELESLDDDDI---EWLHGMIQAHVDATDSAVGQR
MMAR_5413|M.marinum_M               YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR
MUL_5037|M.ulcerans_Agy99           YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR
MAB_0091|M.abscessus_ATCC_1997      YDPDKRLMDNLNDEMVDLDALDPDDQ---QVLRSLIEKHVAATDSAVGQR
                                    **.   :  .** ***::: :   *      : . :  ** *****:***

Mflv_1114|M.gilvum_PYR-GCK          ILADWSGEQVHFKKVMPRDYKRVLEAIAEAERAGADENGVAEAIMAAANG
Mvan_5698|M.vanbaalenii_PYR-1       ILADWNTELGHFKKVMPRDFKRVLQAIAEAQQSGADENGVAEAIMAAANG
MSMEG_6459|M.smegmatis_MC2_155      ILADWDNELKHFAKVMPRDYKRVLAAIAEAEAKGLTGSDIDDAIMAASNG
TH_2102|M.thermoresistible__bu      ILNDWDEHVTHFAKVMPRDYKRVLTAIAEAEASGAD---VDEAIMAAANG
Mb3889c|M.bovis_AF2122/97           ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG
Rv3859c|M.tuberculosis_H37Rv        ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG
MLBr_00061|M.leprae_Br4923          ILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVD---VNKVIMEPAHG
MAV_0166|M.avium_104                ILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGD---VDKAIMAAAHG
MMAR_5413|M.marinum_M               VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG
MUL_5037|M.ulcerans_Agy99           VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG
MAB_0091|M.abscessus_ATCC_1997      ILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGD---VNEAIMAAARG
                                    :* .*  .   * ****:*::*** *** *:  *     : ..** .:.*