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TPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLNLEHRGAAGAEPRSGDGAGILIQVPDAF LREVVDFELPAPGSYATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTDDSSLGALSRDAMPT FRQVFLAGASDMTLERRCYVIRKRAEHELGTKGPGQDGPGRETVYFPSLSGRTFVYKGMLTTPQLKAFYL DLQDDRLTSALGIVHSRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVE KLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSRRAFYQYHSSLMEPWDGPA SMTFTDGTIIGAVLDRNGLRPSRIWVTEDGLVVMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIV SDEEIKAELAAEHPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAPMVRTGAEP IGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREEVVTSLQGTTGGERDLLNPDENSCHQIQL PQPILRNHELAKLINLDPETVINGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADGARIIV LSDRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAREVHHMAMLLGCGAAAVNPYLAFESI EDMLDRGVIDGIDRNTALSNYVKAAGKGVLKVMSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCA TGGITLDDIAADVATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHSTRTGQYKIF KEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNR LGGRSNSGEGGEDVGRFEQDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGH KVYPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVKLVSENGVGTVAAGVSKAH ADVVLISGHDGGTGATPLTSMKHAGAPWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGG EEFGFATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREYMAQLGFRT INEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQDLYCSSSQDHGLDKALDQQLIVMSREALD SGKPVRFATTISNVNRTVGTMLGHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDAND YVGKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGERFAVRNSGAHAVVEGVGD HGCEYMTGGRVVILGQTGRNFAAGMSGGIAYVYDPDGELPDNLNTEMVDVETLDDDDSEFVHGIVQAHVD ATDSAVGQRVLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVDIDKAIMAASHG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5413 | gltB | - | 100% (1527) | ferredoxin-dependent glutamate synthase |
M. marinum M | MMAR_1226 | gltB_1 | 6e-20 | 30.20% (202) | glutamate synthase, GltB_1 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3889c | gltB | 0.0 | 91.75% (1527) | putative ferredoxin-dependent glutamate synthase |
M. gilvum PYR-GCK | Mflv_1114 | - | 0.0 | 84.54% (1533) | glutamate synthase (ferredoxin) |
M. tuberculosis H37Rv | Rv3859c | gltB | 0.0 | 91.68% (1527) | ferredoxin-dependent glutamate synthase |
M. leprae Br4923 | MLBr_00061 | gltB | 0.0 | 88.28% (1527) | putative ferredoxin-dependent glutamate synthase |
M. abscessus ATCC 19977 | MAB_0091 | - | 0.0 | 82.36% (1525) | putative ferredoxin-dependent glutamate synthase |
M. avium 104 | MAV_0166 | - | 0.0 | 91.29% (1527) | ferredoxin-dependent glutamate synthase 1 |
M. smegmatis MC2 155 | MSMEG_6459 | - | 0.0 | 84.45% (1524) | ferredoxin-dependent glutamate synthase 1 |
M. thermoresistible (build 8) | TH_2102 | gltB | 0.0 | 84.00% (1531) | PROBABLE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE |
M. ulcerans Agy99 | MUL_5037 | gltB | 0.0 | 99.28% (1527) | ferredoxin-dependent glutamate synthase |
M. vanbaalenii PYR-1 | Mvan_5698 | - | 0.0 | 85.02% (1515) | glutamate synthase (ferredoxin) |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1114|M.gilvum_PYR-GCK -------------MAPSRQGLYDPAFEHDSCGVAMVADIHGRRSRDIVEK Mvan_5698|M.vanbaalenii_PYR-1 ----------------------------------MVADMHGRRSRDIVDK MSMEG_6459|M.smegmatis_MC2_155 MGMTPSSFGGSGRSSRDNRGLYNPAYEHDACGVAMVADMHGRRSRDIVDK TH_2102|M.thermoresistible__bu -------------MTPKAQGLYNPAFEHDACGVAMVADMYGRRSRDIVDK MMAR_5413|M.marinum_M -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK MUL_5037|M.ulcerans_Agy99 -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK Mb3889c|M.bovis_AF2122/97 -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK Rv3859c|M.tuberculosis_H37Rv -------------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDK MLBr_00061|M.leprae_Br4923 -------------MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDK MAV_0166|M.avium_104 -----------MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDK MAB_0091|M.abscessus_ATCC_1997 -------------MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDK **.*::***:****:* Mflv_1114|M.gilvum_PYR-GCK AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVC----GFDLPEP Mvan_5698|M.vanbaalenii_PYR-1 AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFFRAVCEKE-GFDLPEA MSMEG_6459|M.smegmatis_MC2_155 AITALVNLEHRGAQGAEPNTGDGAGILIQVPDAFLRAVV----DFDLPEP TH_2102|M.thermoresistible__bu AITALLNLEHRGAQGAEPNTGDGAGILLQVPDEFLRAVVEEQGDFELPPP MMAR_5413|M.marinum_M AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP MUL_5037|M.ulcerans_Agy99 AITALLNLEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP Mb3889c|M.bovis_AF2122/97 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP Rv3859c|M.tuberculosis_H37Rv AITALLNLEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP MLBr_00061|M.leprae_Br4923 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLRAVV----DFELPAA MAV_0166|M.avium_104 AITALLNLEHRGAQGAEPRSGDGAGILIQVPDAFLREVV----DFELPPE MAB_0091|M.abscessus_ATCC_1997 AITALLNLEHRGAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAE *****:******* ****.:******::*:** *:* . .*:** Mflv_1114|M.gilvum_PYR-GCK GSFATGIAFLPQSAKDAATACESVEKIAEAEGLRVLGWRDVPTDDSSLGA Mvan_5698|M.vanbaalenii_PYR-1 GSYATGMAFLPQSSKDAAIACAAVEKIAEAEGLQVLGWRDVPTDDSSLGA MSMEG_6459|M.smegmatis_MC2_155 GSYATGMAFLPQSSRDAAAACESVEKIAEAEGLEVLGWREVPTDDSSLGA TH_2102|M.thermoresistible__bu GSYATGIAFLPQSAKDAAQACDAVEKIVEAEGLTVLGWREVPIDDSSLGA MMAR_5413|M.marinum_M GSYATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTDDSSLGA MUL_5037|M.ulcerans_Agy99 GSYATGIAFLPQSSKDAAAACAAVEKIGEAEGLQVLGWRNVPTDDSSLGA Mb3889c|M.bovis_AF2122/97 GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA Rv3859c|M.tuberculosis_H37Rv GSYATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTDDSSLGA MLBr_00061|M.leprae_Br4923 SSYATGIAFLPQSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTDASSLGA MAV_0166|M.avium_104 GSYATGIAFLPQSSKDAATACAAVEKIAEAEGLTVLGWRNVPTDDSSLGA MAB_0091|M.abscessus_ATCC_1997 GSYASGIAFLPQGSKDAATACEAVEKIVEAEGLTVLGWREVPHDDSSLGA .*:*:*:*****.::*** ** :*:** **** *****.** * ***** Mflv_1114|M.gilvum_PYR-GCK LARDAMPTFRQVFMAGAEGMDLERRAYVVRKRAEHELGTKGPGQDGPGRE Mvan_5698|M.vanbaalenii_PYR-1 LARDAMPTFRQIFLAGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE MSMEG_6459|M.smegmatis_MC2_155 LARDAMPTFRQLFLGGASGMELERRAYVVRKRAEHELGTKGPGQDGPGRE TH_2102|M.thermoresistible__bu LARDAMPTFRQLFLGGATGIDLERRAYVVRKRAEHELGTKGPGQDGPGRE MMAR_5413|M.marinum_M LSRDAMPTFRQVFLAGASDMTLERRCYVIRKRAEHELGTKGPGQDGPGRE MUL_5037|M.ulcerans_Agy99 LSRDAMPTFRQVFLAGASDMALERRCYVIRKRAEHELGTKGPGQDGPGRE Mb3889c|M.bovis_AF2122/97 LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE Rv3859c|M.tuberculosis_H37Rv LSRDAMPTFRQVFLAGASGMALERRCYVVRKRAEHELGTKGPGQDGPGRE MLBr_00061|M.leprae_Br4923 LSRDAMPTFRQVFMAGATGLTLERRAYVIRKRAEHELGTKGPGQDGPGRE MAV_0166|M.avium_104 LSRDAMPTFRQVFMAGASGMTLERRAYLVRKRAEHELGTKGPGQDGPGRE MAB_0091|M.abscessus_ATCC_1997 LARDAMPTFRQLFIAGASGIDLERRVYVVRKRIEHELGNQGSGRGSLGEE *:*********:*:.** .: **** *::*** *****.:*.*:.. *.* Mflv_1114|M.gilvum_PYR-GCK TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT Mvan_5698|M.vanbaalenii_PYR-1 TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERMTSALGIVHSRFSTNT MSMEG_6459|M.smegmatis_MC2_155 TVYFPSLSGQTFVYKGMLTTPQLKQFYLDLQDERLESALGIVHSRFSTNT TH_2102|M.thermoresistible__bu TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERLTSALAIVHSRFSTNT MMAR_5413|M.marinum_M TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT MUL_5037|M.ulcerans_Agy99 TVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT Mb3889c|M.bovis_AF2122/97 TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT Rv3859c|M.tuberculosis_H37Rv TVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVHSRFSTNT MLBr_00061|M.leprae_Br4923 TIYFPSLSSQTFVYKGMLTTPQLKAFYRDLQDERLTSALGIVHSRFSTNT MAV_0166|M.avium_104 TVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVHSRFSTNT MAB_0091|M.abscessus_ATCC_1997 TVYFPSLSGRTFVYKGMLTTPQLRAFYLDLQDERVESALGIVHSRFSTNT *:******.:*:***********: ** ****:*: ***.********** Mflv_1114|M.gilvum_PYR-GCK FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDVFGAKADLDKI Mvan_5698|M.vanbaalenii_PYR-1 FPSWPLAHPFRRVAHNGEINTVTGNENWMRAREALIKTDIFGGQ-DLEKV MSMEG_6459|M.smegmatis_MC2_155 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDVFGSD-GLDKI TH_2102|M.thermoresistible__bu FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDLFGGQ-DLEKV MMAR_5413|M.marinum_M FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL MUL_5037|M.ulcerans_Agy99 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEANVEKL Mb3889c|M.bovis_AF2122/97 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL Rv3859c|M.tuberculosis_H37Rv FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGSAADVEKL MLBr_00061|M.leprae_Br4923 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALMKTDIFGSKADMEKL MAV_0166|M.avium_104 FPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGTEADVEKL MAB_0091|M.abscessus_ATCC_1997 FPSWPLAHPYRRVAHNGEINTVAGNENWMRAREALIKTDVFGDPAQLEKI *********:**:*********:************::**:** ::*: Mflv_1114|M.gilvum_PYR-GCK TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR Mvan_5698|M.vanbaalenii_PYR-1 TPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHESMDPAR MSMEG_6459|M.smegmatis_MC2_155 VPVCTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWERHEDMDPAR TH_2102|M.thermoresistible__bu APICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWEQHESMDPAR MMAR_5413|M.marinum_M FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR MUL_5037|M.ulcerans_Agy99 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHASMDPSR Mb3889c|M.bovis_AF2122/97 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR Rv3859c|M.tuberculosis_H37Rv FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR MLBr_00061|M.leprae_Br4923 FPICTPGASDTARFDEALELLHLGGRSLVHAVLMMIPEAWERHESMDPAR MAV_0166|M.avium_104 FPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERHESMDPAR MAB_0091|M.abscessus_ATCC_1997 FPICTRGASDTARFDEALELLHLGGRPLHHAVLMMIPEAWERHENMSAEL *:** **********.*********.* ************:* .*.. Mflv_1114|M.gilvum_PYR-GCK RAFYEFHDSLMEPWDGPAAVCFTDGTVIGAVLDRNGLRPSRIWVTEDGLV Mvan_5698|M.vanbaalenii_PYR-1 RAFYQYHASLMEPWDGPAAVCFTDGTVVGAVLDRNGLRPSRIWVTSDGLV MSMEG_6459|M.smegmatis_MC2_155 RAFYEYHASLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTDDGLV TH_2102|M.thermoresistible__bu RAFYEFHDSLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIWVTADGLV MMAR_5413|M.marinum_M RAFYQYHSSLMEPWDGPASMTFTDGTIIGAVLDRNGLRPSRIWVTEDGLV MUL_5037|M.ulcerans_Agy99 RAFYQYHSSLMEPWDGPASMTFTDGTMVGAVLDRNGLRPSRIWVTEDGLV Mb3889c|M.bovis_AF2122/97 RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV Rv3859c|M.tuberculosis_H37Rv RAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLV MLBr_00061|M.leprae_Br4923 RAFYQYHASLMEPWDGPASMTFTDGVVVGAVLDRNGLRPSRIWITDAGLV MAV_0166|M.avium_104 RAFYQYHASLMEPWDGPASMTFTDGTVIGAVLDRNGLRPSRIWVTEDGLV MAB_0091|M.abscessus_ATCC_1997 RSFYEFHASLMEPWDGPASVCFTDGTIVGAVLDRNGLRPSRVWVTNDGLV *:**::* **********:: ****.::*************:*:* *** Mflv_1114|M.gilvum_PYR-GCK VMASEAGVLDLDPSTVVKKMRLQPGRMFLVDTAQGRIVDDEEIKAQLAAE Mvan_5698|M.vanbaalenii_PYR-1 VMASEAGVLDLDPGTVVQKMRLQPGRMFLVDTAQGRIVSDEEIKAELAAG MSMEG_6459|M.smegmatis_MC2_155 VMASEAGVLPLDPAKVVKKMRLQPGRMFLVDTAQGRIVDDEEVKAELAAA TH_2102|M.thermoresistible__bu VMASEAGVLNLDPATVVRKMRLQPGRMFLVDTAQGRIIDDEEIKAELAAE MMAR_5413|M.marinum_M VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE MUL_5037|M.ulcerans_Agy99 VMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEAIKAELAAE Mb3889c|M.bovis_AF2122/97 VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE Rv3859c|M.tuberculosis_H37Rv VMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEIKADLAAE MLBr_00061|M.leprae_Br4923 VMASEAGVLDLDPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAKLAAE MAV_0166|M.avium_104 VMASEAGVLDLDPATVVRRMRLQPGRMFLVDTAQGRIVSDEEIKAELAAE MAB_0091|M.abscessus_ATCC_1997 VMASEAGVLDLDPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEVKAELAAA ********* *.*. **:: ************:****:.** :**.*** Mflv_1114|M.gilvum_PYR-GCK HPYQEWLDAGLFQLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP Mvan_5698|M.vanbaalenii_PYR-1 QPYQEWLDAGLFHLDELPQGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP MSMEG_6459|M.smegmatis_MC2_155 EPYQEWLEQGLFHLDELPPGDYVRMPHHRVVLRQQIFGYTYEELNLLVAP TH_2102|M.thermoresistible__bu HPYQEWLDAGLFPLDELPQGDYQRMPHHRVVLRQRVFGYTSEELNLIVGP MMAR_5413|M.marinum_M HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP MUL_5037|M.ulcerans_Agy99 HPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEELNLLVAP Mb3889c|M.bovis_AF2122/97 HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP Rv3859c|M.tuberculosis_H37Rv HPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEELNLLVAP MLBr_00061|M.leprae_Br4923 HPYQEWLDKGLVPIDELPAGKYVRMPHHRLVMRQLAFGYTYEELNLLVAP MAV_0166|M.avium_104 HPYQEWLDRNLVPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEELNLLVAP MAB_0091|M.abscessus_ATCC_1997 EPYQRWLEEGLVRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEEINLLVAP .***.**: .*. ::.** :*.*.*:* ** **** **:**:*.* Mflv_1114|M.gilvum_PYR-GCK MARNGAEALGSMGTDTPIAVLSSRPRMLYDYFQQLFAQVTNPPLDAIREE Mvan_5698|M.vanbaalenii_PYR-1 MARSGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE MSMEG_6459|M.smegmatis_MC2_155 MARTGAEALGSMGTDTPIAVLSARPRMLFDYFQQLFAQVTNPPLDAIREE TH_2102|M.thermoresistible__bu MARTGAEPLGSMGTDTPIAVLSQRSRLLFDYFQQMFAQVTNPPLDAIREE MMAR_5413|M.marinum_M MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE MUL_5037|M.ulcerans_Agy99 MVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPPLDAIREE Mb3889c|M.bovis_AF2122/97 MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE Rv3859c|M.tuberculosis_H37Rv MARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPPLDAIREE MLBr_00061|M.leprae_Br4923 MVRAGSEPIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPPLDAIREE MAV_0166|M.avium_104 MVRTGAEPIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPPLDAIREE MAB_0091|M.abscessus_ATCC_1997 MARTGAEALGSMGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPPLDAIREE *.* *:*.:****:***:**** *.*:*:***:*:*************** Mflv_1114|M.gilvum_PYR-GCK VVTSLQGAMGPEGDLLNPGPESCRQIVLPQPILRNAELSKLICVDPDHEI Mvan_5698|M.vanbaalenii_PYR-1 VVTSLQGTVGPEGDLLNPDAESCRQIVLPNPILRNAELSKLICVDPDHEI MSMEG_6459|M.smegmatis_MC2_155 VVTSLQGTVGPEGDLLNPGPESCRQIVLPQPILRNADLSKLICVDPDHEI TH_2102|M.thermoresistible__bu VITSLQGVIGPEGDLLNPGPESCRQIVLPQPILRNHELAKLINVDPDHEV MMAR_5413|M.marinum_M VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI MUL_5037|M.ulcerans_Agy99 VVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLINLDPETVI Mb3889c|M.bovis_AF2122/97 VVTSLQGTTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVSLDPNDKV Rv3859c|M.tuberculosis_H37Rv VVTSLQGTTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVSLDPNDKV MLBr_00061|M.leprae_Br4923 VVTSLQGTTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVNLDPADEV MAV_0166|M.avium_104 VVTSLQGTTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVNLNPDDEV MAB_0091|M.abscessus_ATCC_1997 VVTSLGGVIGPEGDLLHPTAESCHQILLPQPVLHNDELDKLIHLDPADTV *:*** *. * * *** * **:** *.:*:*:* :* **: ::* : Mflv_1114|M.gilvum_PYR-GCK RGHKHGMRAAVIRCLYPVNRGGQGLKEALDNVRAKVSSAIRDGARIIVLS Mvan_5698|M.vanbaalenii_PYR-1 RGHKHGMRAAVIRCLYPVNRGGRGLKEALDNVRAKVSAAIRDGARIIVLS MSMEG_6459|M.smegmatis_MC2_155 RGHKHGMRAAVIRCLYPVNRGGVGLKEALDNVRAKVSEAIREGARIIVLS TH_2102|M.thermoresistible__bu RGRKHGMRAAVVRCLFPVNRGGQGLKEALDRVRAKVSAAIREGARIIVLS MMAR_5413|M.marinum_M NGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADGARIIVLS MUL_5037|M.ulcerans_Agy99 NGRPHGLKSKVVRCLYPVAEGGSGLAAALNEVRAQASAAIADGARIIVLS Mb3889c|M.bovis_AF2122/97 NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS Rv3859c|M.tuberculosis_H37Rv NGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADGARIIILS MLBr_00061|M.leprae_Br4923 NGRPHGMRSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGGARVIILS MAV_0166|M.avium_104 NGRPHGMRSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADGARVIILS MAB_0091|M.abscessus_ATCC_1997 NGRAHGFSSRVIRCLYPVAEGGAGLRTALESVRAEVSAAIAGGAQVIILS .*: **: : *: **: * .* ** ** **. .: ** **::*:** Mflv_1114|M.gilvum_PYR-GCK DRESDEQMAPIPSLLSVSAVHHHLVRERTRTQVGLIVEAGDAREVHHMAA Mvan_5698|M.vanbaalenii_PYR-1 DRESNEQMAPIPSLLSVSAVHHHLVRDRTRTKVGLVVEAGDAREVHHMAA MSMEG_6459|M.smegmatis_MC2_155 DRESNETMAPIPSLLSVAAVHHHLVRERTRTKVGLVVEAGDAREVHHMAT TH_2102|M.thermoresistible__bu DRESDEQLAPIPSLLSVAAVHHHLVRDRTRTQVGLVVEAGDAREVHHMAA MMAR_5413|M.marinum_M DRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAREVHHMAM MUL_5037|M.ulcerans_Agy99 DRESDERMAPIPALLAVAGVHHHLVRERTRTKVGLVVESGDAREVHHMAM Mb3889c|M.bovis_AF2122/97 DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA Rv3859c|M.tuberculosis_H37Rv DRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAREVHHMAA MLBr_00061|M.leprae_Br4923 DRNSDEQMAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAREVHHMAA MAV_0166|M.avium_104 DRESDEKMAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAREVHHMAA MAB_0091|M.abscessus_ATCC_1997 DRESDDLMAPIPSLLAVAAVHHHLVRERSRTKVGLVVEAGDAREVHHVAA **:*:: :****:**:*:.*******:*:**:***:**:********:* Mflv_1114|M.gilvum_PYR-GCK LCGFGAAAINPYMAFESIEDMVDRGVITDITSDQAKANYVKAAGKGVLKV Mvan_5698|M.vanbaalenii_PYR-1 LCGFGAAAINPYMAFESIEDMVDRGVISGISSDQAKANYVKAAGKGVLKV MSMEG_6459|M.smegmatis_MC2_155 LVGFGAAAINPYMAFESIEDMVDRGVITGLTSDQAKANYVKAAGKGVLKV TH_2102|M.thermoresistible__bu LIGFGASAINPYLAFESIEDMLDRNLLEGLDRETALNNYIKAAGKGVLKV MMAR_5413|M.marinum_M LLGCGAAAVNPYLAFESIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV MUL_5037|M.ulcerans_Agy99 LLGCGAAAVNPYLAFASIEDMLDRGVIDGIDRNTALSNYVKAAGKGVLKV Mb3889c|M.bovis_AF2122/97 LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV Rv3859c|M.tuberculosis_H37Rv LVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAAGKGVLKV MLBr_00061|M.leprae_Br4923 LIGFGAAAVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKATGQGVLKI MAV_0166|M.avium_104 LVGFGAAAINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAAGKGVLKV MAB_0091|M.abscessus_ATCC_1997 LVGFGAAAVNPYMAFESIEDLIDRGVITGVDRDKAIRNYIKAAGKGVLKV * * **:*:***:.* ***:::**.:: .: * **:**:*:****: Mflv_1114|M.gilvum_PYR-GCK MSKMGISTLASYTGAQLFQAIGINQQVLDDYFTGLTCPVGGIDLDDIAAD Mvan_5698|M.vanbaalenii_PYR-1 MSKMGISTLASYTGAQLFQAIGISQAVLDEYFAGLSCPVGGIDLDDIADD MSMEG_6459|M.smegmatis_MC2_155 MSKMGISTLASYTGAQLFQAIGISQQVLDEYFTGLSCPVGGIDLEDIAAD TH_2102|M.thermoresistible__bu MSKMGISTLRSYTGAQLFQAIGISQEVLDEYFTGLSCPTGGIDLDDIAAD MMAR_5413|M.marinum_M MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD MUL_5037|M.ulcerans_Agy99 MSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGITLDDIAAD Mb3889c|M.bovis_AF2122/97 MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD Rv3859c|M.tuberculosis_H37Rv MSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGITLDDIAAD MLBr_00061|M.leprae_Br4923 MSKMGISTLASYVGAQLFQAVGISEDVLDEYFSGLSCPTGGITLDDIAAE MAV_0166|M.avium_104 MSKMGISTLASYTGAQLFQAVGISEDVLDEYFTGLSCPIGGITLDDIAAD MAB_0091|M.abscessus_ATCC_1997 MSKMGISTLASYTGAQLFQAIGLSQELLDEYFTGLACPTGGIGLDEIAAD ********* **.*******:*:.: :*::**:**:*. *** *::** : Mflv_1114|M.gilvum_PYR-GCK IASRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST Mvan_5698|M.vanbaalenii_PYR-1 VATRHALAYLDRPDEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST MSMEG_6459|M.smegmatis_MC2_155 VAARHSLAFLDRPDERAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST TH_2102|M.thermoresistible__bu VARRHELAYLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST MMAR_5413|M.marinum_M VATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST MUL_5037|M.ulcerans_Agy99 VASRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST Mb3889c|M.bovis_AF2122/97 VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST Rv3859c|M.tuberculosis_H37Rv VAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHST MLBr_00061|M.leprae_Br4923 VAVRHRVAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT MAV_0166|M.avium_104 VAARHALAYLDRPNERAHRELEVGGEYQWRREGEYHLFNPETVFKLQHAT MAB_0091|M.abscessus_ATCC_1997 VASRHNLAFLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTVFKLQHST :* ** :*:****:* ************************:*******:* Mflv_1114|M.gilvum_PYR-GCK RTGQYSIFKEYTQLVDDQSERMASLRGLLKFRDGERPSVPLDEVEPASEI Mvan_5698|M.vanbaalenii_PYR-1 RTGQYSVFKEYTSLVDDQSERMASLRGLLKFREGVRPPVPLEEVEPASEI MSMEG_6459|M.smegmatis_MC2_155 RTGQYSIFKEYTKLVDDQSERIASLRGLLKFREGHRPPVPIEEVEPASEI TH_2102|M.thermoresistible__bu RTGQYEIFKEYTRLVDDQSERMASLRGLLKFKEGVRPPVPIEEVEPASEI MMAR_5413|M.marinum_M RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI MUL_5037|M.ulcerans_Agy99 RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDEVEPASEI Mb3889c|M.bovis_AF2122/97 RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI Rv3859c|M.tuberculosis_H37Rv RTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDEVEPASEI MLBr_00061|M.leprae_Br4923 RSGQYKIFKEYTRLVDDQSERMASLRGLLKFRSGVRTPVPLDEVEPASEI MAV_0166|M.avium_104 RTGQYKIFKDYTRLVDDQSERMASLRGLLKFRAGVRPPVPLEEVEPASEI MAB_0091|M.abscessus_ATCC_1997 RTGQYSVFKEYTQLVDDQSERMASLRGLLKFKTGVRPPVPLDEVEPASEI *:***.:**:** ********:*********: * *..:*::******** Mflv_1114|M.gilvum_PYR-GCK VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVSRFDRDEN Mvan_5698|M.vanbaalenii_PYR-1 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGESVTRFDPDEN MSMEG_6459|M.smegmatis_MC2_155 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEAVHRFNPDEN TH_2102|M.thermoresistible__bu VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNSGEGGEHVSRFDPDDN MMAR_5413|M.marinum_M VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN MUL_5037|M.ulcerans_Agy99 VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVGRFEQDPN Mb3889c|M.bovis_AF2122/97 VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN Rv3859c|M.tuberculosis_H37Rv VKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVKRFDRDPN MLBr_00061|M.leprae_Br4923 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVNRFEPDPN MAV_0166|M.avium_104 VKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVKRFDRDPD MAB_0091|M.abscessus_ATCC_1997 VKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDPRRFTPDEN **********:*******************.***.***** ** * : Mflv_1114|M.gilvum_PYR-GCK GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV Mvan_5698|M.vanbaalenii_PYR-1 GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV MSMEG_6459|M.smegmatis_MC2_155 GDWRRSAIKQVASGRFGVTSHYLANCTDIQIKMAQGAKPGEGGQLPGHKV TH_2102|M.thermoresistible__bu GDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGNKV MMAR_5413|M.marinum_M GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV MUL_5037|M.ulcerans_Agy99 GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV Mb3889c|M.bovis_AF2122/97 GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV Rv3859c|M.tuberculosis_H37Rv GDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGGQLPGHKV MLBr_00061|M.leprae_Br4923 GDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGRKV MAV_0166|M.avium_104 GSWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGGQLPGHKV MAB_0091|M.abscessus_ATCC_1997 GDWRRSAIKQVASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGGQLPAHKV *.***********.*********:****:*****************..** Mflv_1114|M.gilvum_PYR-GCK YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK Mvan_5698|M.vanbaalenii_PYR-1 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARIHVK MSMEG_6459|M.smegmatis_MC2_155 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARIHVK TH_2102|M.thermoresistible__bu YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARVHVK MMAR_5413|M.marinum_M YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MUL_5037|M.ulcerans_Agy99 YPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK Mb3889c|M.bovis_AF2122/97 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK Rv3859c|M.tuberculosis_H37Rv YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MLBr_00061|M.leprae_Br4923 YPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPSARVHVK MAV_0166|M.avium_104 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPAARVHVK MAB_0091|M.abscessus_ATCC_1997 YPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNPQARIHVK ***:*:**:*******************************:** **:*** Mflv_1114|M.gilvum_PYR-GCK LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL Mvan_5698|M.vanbaalenii_PYR-1 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MSMEG_6459|M.smegmatis_MC2_155 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL TH_2102|M.thermoresistible__bu LVSEAGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGAPWELGL MMAR_5413|M.marinum_M LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MUL_5037|M.ulcerans_Agy99 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL Mb3889c|M.bovis_AF2122/97 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL Rv3859c|M.tuberculosis_H37Rv LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MLBr_00061|M.leprae_Br4923 LVSENGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSGAPWELGL MAV_0166|M.avium_104 LVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL MAB_0091|M.abscessus_ATCC_1997 LVSENGVGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAGAPWELGL **** ******:***********:*********:****:**:******** Mflv_1114|M.gilvum_PYR-GCK AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV Mvan_5698|M.vanbaalenii_PYR-1 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVVAALLGAEEFGFATAPLVV MSMEG_6459|M.smegmatis_MC2_155 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV TH_2102|M.thermoresistible__bu AETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGFATAPLVV MMAR_5413|M.marinum_M AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV MUL_5037|M.ulcerans_Agy99 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGFATAPLVV Mb3889c|M.bovis_AF2122/97 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV Rv3859c|M.tuberculosis_H37Rv AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGFATAPLVV MLBr_00061|M.leprae_Br4923 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV MAV_0166|M.avium_104 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGFATAPLVV MAB_0091|M.abscessus_ATCC_1997 AETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGFATAPLVV ******************************::* ***.************ Mflv_1114|M.gilvum_PYR-GCK AGCIMMRVCHLDTCPVGVATQNPVLRKRFNGQPEFVENFFMFIAEEVREL Mvan_5698|M.vanbaalenii_PYR-1 TGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL MSMEG_6459|M.smegmatis_MC2_155 SGCIMMRVCHLDTCPVGVATQNPLLRQRFNGKPEFVENFFMFIAEEVREL TH_2102|M.thermoresistible__bu SGCVMMRVCHLDTCPVGVATQNPVLRQRFTGKPEFVENFFLFIAEEVREY MMAR_5413|M.marinum_M AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY MUL_5037|M.ulcerans_Agy99 AGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFIAEEVREY Mb3889c|M.bovis_AF2122/97 AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY Rv3859c|M.tuberculosis_H37Rv AGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFIAEEVREY MLBr_00061|M.leprae_Br4923 AGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFIAEEVREY MAV_0166|M.avium_104 SGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFIAEEVREY MAB_0091|M.abscessus_ATCC_1997 SGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFIAEEVREL :**:*******************:**:**.*:********:******** Mflv_1114|M.gilvum_PYR-GCK MAELGFRTVNEMVGQVGALDTTQAAERWKAHKLDLTPVLHEPDSAFMNQD Mvan_5698|M.vanbaalenii_PYR-1 MAQLGFRTVNEMVGQVGALDTTQAAEHWKAHKLDLAPVLHEPESAFMNQD MSMEG_6459|M.smegmatis_MC2_155 MAQLGFRTVNEMVGQVGALDTTKAAEHWKAHKLDLTPVLHEPDSAFMNQD TH_2102|M.thermoresistible__bu MAKMGFRTVNEMVGQVGMLDTTRAAEHWKAHKLDLSPVLHQPESAFMNQD MMAR_5413|M.marinum_M MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQD MUL_5037|M.ulcerans_Agy99 MAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPESAFMNQG Mb3889c|M.bovis_AF2122/97 LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD Rv3859c|M.tuberculosis_H37Rv LAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPESAFMNQD MLBr_00061|M.leprae_Br4923 MAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPESAFMNQD MAV_0166|M.avium_104 MAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPESAFMNQD MAB_0091|M.abscessus_ATCC_1997 MAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPESAFMNQD :*::****.** ***. ** . :*** :** *** :*:******. Mflv_1114|M.gilvum_PYR-GCK LYCSSRQDHGLDKALDQQLITQSREAIDNGTPVRFSTTIANVNRTVGTML Mvan_5698|M.vanbaalenii_PYR-1 LYCSSRQDHGLDKALDQQLIAQCREALDRGTPVRFSTTIANVNRTVGTML MSMEG_6459|M.smegmatis_MC2_155 LYCSSRQDHGLDKALDQQLIVQSREALDSGTPVRFTAKITNVNRTVGTML TH_2102|M.thermoresistible__bu LYCSSRQDHGLDKALDQQLITMCREALDNGTPVRFSTTIANVNRTVGTML MMAR_5413|M.marinum_M LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML MUL_5037|M.ulcerans_Agy99 LYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISNVNRTVGTML Mb3889c|M.bovis_AF2122/97 LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML Rv3859c|M.tuberculosis_H37Rv LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGNVNRTVGTML MLBr_00061|M.leprae_Br4923 LYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGNVNRTVGTML MAV_0166|M.avium_104 LYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISNVNRTVGTML MAB_0091|M.abscessus_ATCC_1997 LYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITNVNRTVGTML ****. *****:*.******. .*:*:* *.**:* : * ********** Mflv_1114|M.gilvum_PYR-GCK GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFLPKGITLRVYGDANDYV Mvan_5698|M.vanbaalenii_PYR-1 GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV MSMEG_6459|M.smegmatis_MC2_155 GHEVTKAYGGQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV TH_2102|M.thermoresistible__bu GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV MMAR_5413|M.marinum_M GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV MUL_5037|M.ulcerans_Agy99 GHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLRIYGDANDYV Mb3889c|M.bovis_AF2122/97 GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV Rv3859c|M.tuberculosis_H37Rv GHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLRVYGDANDYV MLBr_00061|M.leprae_Br4923 GHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLRVYGDANDYV MAV_0166|M.avium_104 GHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLRVYGDANDYV MAB_0091|M.abscessus_ATCC_1997 GHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLRLFGDANDYV ***:*****.:****.:***** **********:*:*****::******* Mflv_1114|M.gilvum_PYR-GCK GKGLSGGRVVVRPSDNAPEGYVAEDNIIAGNVVLFGATSGEMFLRGQVGE Mvan_5698|M.vanbaalenii_PYR-1 GKGLSGGRVVVRPSDGAPEGYAAEGNIIAGNVVLFGATSGQMFLRGQVGE MSMEG_6459|M.smegmatis_MC2_155 GKGLSGGRIVVRPADEAPESFAAEDNIIAGNVVLFGATSGEAFLRGQVGE TH_2102|M.thermoresistible__bu GKGLSGGRIVVRPPDNVPESFVAEDNIIAGNVILFGATSGEVFLRGQVGE MMAR_5413|M.marinum_M GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE MUL_5037|M.ulcerans_Agy99 GKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGEVFLRGVVGE Mb3889c|M.bovis_AF2122/97 GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE Rv3859c|M.tuberculosis_H37Rv GKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGEVYLRGVVGE MLBr_00061|M.leprae_Br4923 GKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGEVYLRGVVGE MAV_0166|M.avium_104 GKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGEAYLRGVVGE MAB_0091|M.abscessus_ATCC_1997 GKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGEAFLNGVVGE *******::****. .* .:.** ***.***:*******: :*.* *** Mflv_1114|M.gilvum_PYR-GCK RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGVGYV Mvan_5698|M.vanbaalenii_PYR-1 RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV MSMEG_6459|M.smegmatis_MC2_155 RFAVRNSGAVAVVEGVGDHGCEYMTGGRVVILGPTGRNFAAGMSGGIAYV TH_2102|M.thermoresistible__bu RFAVRNSGALAVVEGVGDHGCEYMTGGRVVILGPVGRNFAAGMSGGIAYV MMAR_5413|M.marinum_M RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV MUL_5037|M.ulcerans_Agy99 RFAVRNSGAHVVVEGVGDHGCEYMTGGRVVILGQTGRNFAAGMSGGIAYV Mb3889c|M.bovis_AF2122/97 RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV Rv3859c|M.tuberculosis_H37Rv RFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAAGMSGGVAYV MLBr_00061|M.leprae_Br4923 RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAAGMSGGEAYV MAV_0166|M.avium_104 RFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAAGMSGGVAYI MAB_0091|M.abscessus_ATCC_1997 RFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAAGMSGGVAYV ********* .**************** **:** .*********** .*: Mflv_1114|M.gilvum_PYR-GCK YDPQDALAGNLNAEMVELESLGDSDSDDAVFVHGMIQAHVGATDSAVGQR Mvan_5698|M.vanbaalenii_PYR-1 YDPDNTLADNLNAEMVELEGMGGIDSDDAVFVHGIVQEHVDATDSAVGQR MSMEG_6459|M.smegmatis_MC2_155 YDPRAALPKNLNPEMVEIEALEEADT---EWLRGILASHVDATDSAVGQR TH_2102|M.thermoresistible__bu YDPDGVLPGRLNREMVELESLDDEDR---EWLRGFIAAHVDATDSAIGQR MMAR_5413|M.marinum_M YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR MUL_5037|M.ulcerans_Agy99 YDPDGELPDNLNTEMVDVETLDDDDS---EFVHGIVQAHVDATDSAVGQR Mb3889c|M.bovis_AF2122/97 YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR Rv3859c|M.tuberculosis_H37Rv YDPDGELPANLNSEMVELETLDEDDA---DWLHGTIQVHVDATDSAVGQR MLBr_00061|M.leprae_Br4923 YDSDGELPANLNFEMVELEPLDFDDA---AWLYATIQAHVDATDSAVGQR MAV_0166|M.avium_104 YDPPGEFPQHLNAEMVELESLDDDDI---EWLHGMIQAHVDATDSAVGQR MAB_0091|M.abscessus_ATCC_1997 YDPDKRLMDNLNDEMVDLDALDPDDQ---QVLRSLIEKHVAATDSAVGQR **. : .** ***::: : * : . : ** *****:*** Mflv_1114|M.gilvum_PYR-GCK ILADWSGEQVHFKKVMPRDYKRVLEAIAEAERAGADENGVAEAIMAAANG Mvan_5698|M.vanbaalenii_PYR-1 ILADWNTELGHFKKVMPRDFKRVLQAIAEAQQSGADENGVAEAIMAAANG MSMEG_6459|M.smegmatis_MC2_155 ILADWDNELKHFAKVMPRDYKRVLAAIAEAEAKGLTGSDIDDAIMAASNG TH_2102|M.thermoresistible__bu ILNDWDEHVTHFAKVMPRDYKRVLTAIAEAEASGAD---VDEAIMAAANG MMAR_5413|M.marinum_M VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG MUL_5037|M.ulcerans_Agy99 VLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVD---IDKAIMAASHG Mb3889c|M.bovis_AF2122/97 ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG Rv3859c|M.tuberculosis_H37Rv ILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVD---VDKAIMAAAHG MLBr_00061|M.leprae_Br4923 ILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVD---VNKVIMEPAHG MAV_0166|M.avium_104 ILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGD---VDKAIMAAAHG MAB_0091|M.abscessus_ATCC_1997 ILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGD---VNEAIMAAARG :* .* . * ****:*::*** *** *: * : ..** .:.*