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M. smegmatis MC2 155 MSMEG_3225 (-)

annotation: ferredoxin-dependent glutamate synthase 1
coordinates: 3302712 - 3307268
length: 1518

VLYSALPDAQGLYDPQNEADSCGVAMIADIQGRKSHRIVSDGLIALENLEHRGAAGAEASSGDGAGILIQ
LPVELLREVVDFELPAPTADGDNTFAAGVCFLPQDPVARSAARERIEAIAVEEGLEVLGWRKLPVDPDGA
GIGATALGCMPYMAQFFVTAPETGGARPGGVDLDRLVYPVRKRAEREDVYFPTLSSRTMVYKGMLTTMQL
PQYFLDLRDERCQSAIAIVHSRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAKLASPLIPG
DLSRLSPICSPEASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENATTMGAAERAFWQFHASLMEPWD
GPACVTFTDGTVVGAVLDRNGLRPGRWWRTVDDRVILASEAGVLDVPSGEIVAKGRLQPGKMLLIDTAAG
RIVPDDEIKAQLSAAEPYEEWLHAGLLDLKTLPERGVAKPNHDSVVRRQIAFGYTEEELRVLLTPMAASG
NEPLGSMGTDTPTAVLSSRSRLLYDYFVELFAQVTNPPLDAIREEVVTSMARVMGPEENLLEPTAASCRQ
IVLRAPVIDNDDLGKIVHINDDGEHPGLRATVLRALYDVERGGEGLAEALDDLRRRASEAIADGKRILVL
SDRDSDHTRAPIPSLLAVSAVHHHLVRTKERTKVALVVESGDAREVHHIALLIGFGAAAVNPYLAFESIE
DLIREGELTGIEPAAAVRNYIKALCKGVVKVMSKMGISTVASYTAAQVFEAIGLDRGVIDEYFTGTTSQL
GGVGLDVLADEVKMRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVVFLLQHSTRTGRRDIFA
KYSEEVDRLSRKGGTLRGLFELKTGVRPPVPLEEVEPVESIVTRFNTGAMSYGSISAEAHETMAIAMNKL
GGRSNSGEGGEDVDRLYDPRRRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGGQLPGYKVYPN
IAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANSDARIHVKLVSSVGVGTVAAGVSKAHADVVL
ISGHDGGTGAAPLTSLKHAGAPWEIGLADTQQTLVLNGLRDRITVQCDGGLRTARDVVVAMLLGAEEYGF
ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENFFTFIAEDIRRYLAELGFRSIDEAV
GHAELLDTAEGVAHWKTRGLDLDPIFAVPTDAHGAKLTQRRKLREQDHGLDQALDRTLIQLAEGALEDAH
PVRLELPVRNVNRTVGTLLGSEVTRRYGAAGLPDDTIHVTLTGSAGQSIGAFLPPGITLELVGDANDYVG
KGLSGGRVVVRPPDDVLFLPEDNVIAGNTLMYGATSGEVYLRGRVGERFCARNSGALAVVEGVGDHACEY
MTGGRVVILGKTGRNMAAGMSGGIAFVLGLDPARVNTEMVQLQRLDPEDLEWLHHVVTDHVRYTGSTLGT
SLLSDWPRRSAQFTKIMPTDYQRVLQATRMAKAEGRDVDSAIMEASRG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3225--100% (1518)ferredoxin-dependent glutamate synthase 1
M. smegmatis MC2 155MSMEG_6459-0.063.62% (1542) ferredoxin-dependent glutamate synthase 1
M. smegmatis MC2 155MSMEG_5594-1e-3533.66% (309) ferredoxin-dependent glutamate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3889cgltB0.064.18% (1541) putative ferredoxin-dependent glutamate synthase
M. gilvum PYR-GCKMflv_3593-0.086.55% (1517) glutamate synthase (ferredoxin)
M. tuberculosis H37RvRv3859cgltB0.064.18% (1541) ferredoxin-dependent glutamate synthase
M. leprae Br4923MLBr_00061gltB0.062.13% (1537) putative ferredoxin-dependent glutamate synthase
M. abscessus ATCC 19977MAB_0091-0.062.44% (1544) putative ferredoxin-dependent glutamate synthase
M. marinum MMMAR_5413gltB0.063.21% (1541) ferredoxin-dependent glutamate synthase
M. avium 104MAV_0166-0.063.21% (1541) ferredoxin-dependent glutamate synthase 1
M. thermoresistible (build 8)TH_2102gltB0.064.01% (1545) PROBABLE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE
M. ulcerans Agy99MUL_5037gltB0.062.95% (1544) ferredoxin-dependent glutamate synthase
M. vanbaalenii PYR-1Mvan_2822-0.086.30% (1518) glutamate synthase (ferredoxin)

CLUSTAL 2.0.9 multiple sequence alignment


Mb3889c|M.bovis_AF2122/97           ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN
Rv3859c|M.tuberculosis_H37Rv        ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN
MLBr_00061|M.leprae_Br4923          ------MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLN
MMAR_5413|M.marinum_M               ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN
MUL_5037|M.ulcerans_Agy99           ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN
MAV_0166|M.avium_104                ----MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLN
TH_2102|M.thermoresistible__bu      ------MTPKAQGLYNPAFEHDACGVAMVADMYGRRSRDIVDKAITALLN
MAB_0091|M.abscessus_ATCC_1997      ------MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDKAITALLN
Mflv_3593|M.gilvum_PYR-GCK          MSTLFSALPQPQGLYDPANESDSCGVAMVVDIQGRSSHSIVTDGLIALEH
Mvan_2822|M.vanbaalenii_PYR-1       --MLFSALPDAQGLYDPGNESDSCGVAMVTDIQGRRSHSIVADGLTALEH
MSMEG_3225|M.smegmatis_MC2_155      --MLYSALPDAQGLYDPQNEADSCGVAMIADIQGRKSHRIVSDGLIALEN
                                                ***:*  * *:*****:.*: ** :: ** ..: ** :

Mb3889c|M.bovis_AF2122/97           LEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP-----GS
Rv3859c|M.tuberculosis_H37Rv        LEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP-----GS
MLBr_00061|M.leprae_Br4923          LEHRGAQGAEPRSGDGAGILIQVPDAFLRAVV----DFELPAA-----SS
MMAR_5413|M.marinum_M               LEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP-----GS
MUL_5037|M.ulcerans_Agy99           LEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP-----GS
MAV_0166|M.avium_104                LEHRGAQGAEPRSGDGAGILIQVPDAFLREVV----DFELPPE-----GS
TH_2102|M.thermoresistible__bu      LEHRGAQGAEPNTGDGAGILLQVPDEFLRAVVEEQGDFELPPP-----GS
MAB_0091|M.abscessus_ATCC_1997      LEHRGAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAE-----GS
Mflv_3593|M.gilvum_PYR-GCK          LEHRGAAGAEPNSGDGAGILIQLPVDLLRDVA----DFDLPPATGDG-NT
Mvan_2822|M.vanbaalenii_PYR-1       LEHRGAAGAEPTSGDGAGILIQLPVDLLRAVT----DFALPDPTGDGANT
MSMEG_3225|M.smegmatis_MC2_155      LEHRGAAGAEASSGDGAGILIQLPVELLREVV----DFELPAPTADGDNT
                                    ****** ***. :******::*:*  ::* .     .* **       .:

Mb3889c|M.bovis_AF2122/97           YATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTD--DSSLGA
Rv3859c|M.tuberculosis_H37Rv        YATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTD--DSSLGA
MLBr_00061|M.leprae_Br4923          YATGIAFLPQSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTD--ASSLGA
MMAR_5413|M.marinum_M               YATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTD--DSSLGA
MUL_5037|M.ulcerans_Agy99           YATGIAFLPQSSKDAAAACAAVEKIGEAEGLQVLGWRNVPTD--DSSLGA
MAV_0166|M.avium_104                YATGIAFLPQSSKDAATACAAVEKIAEAEGLTVLGWRNVPTD--DSSLGA
TH_2102|M.thermoresistible__bu      YATGIAFLPQSAKDAAQACDAVEKIVEAEGLTVLGWREVPID--DSSLGA
MAB_0091|M.abscessus_ATCC_1997      YASGIAFLPQGSKDAATACEAVEKIVEAEGLTVLGWREVPHD--DSSLGA
Mflv_3593|M.gilvum_PYR-GCK          FAAGICYLPQDPVQRDAARAAVETIAAEENLDVLGWREVPVDPAGAEIGR
Mvan_2822|M.vanbaalenii_PYR-1       FAAGICFLPQDLAARESARGTVEAIAAEEGLEVLGWREMPVDPDGADLGA
MSMEG_3225|M.smegmatis_MC2_155      FAAGVCFLPQDPVARSAARERIEAIAVEEGLEVLGWRKLPVDPDGAGIGA
                                    :*:*:.:***.      *   :: *   *.* *****.:* *   : :* 

Mb3889c|M.bovis_AF2122/97           LSRDAMPTFRQVFLAG-------ASGMALERRCYVVRKRAEHELGTKGPG
Rv3859c|M.tuberculosis_H37Rv        LSRDAMPTFRQVFLAG-------ASGMALERRCYVVRKRAEHELGTKGPG
MLBr_00061|M.leprae_Br4923          LSRDAMPTFRQVFMAG-------ATGLTLERRAYVIRKRAEHELGTKGPG
MMAR_5413|M.marinum_M               LSRDAMPTFRQVFLAG-------ASDMTLERRCYVIRKRAEHELGTKGPG
MUL_5037|M.ulcerans_Agy99           LSRDAMPTFRQVFLAG-------ASDMALERRCYVIRKRAEHELGTKGPG
MAV_0166|M.avium_104                LSRDAMPTFRQVFMAG-------ASGMTLERRAYLVRKRAEHELGTKGPG
TH_2102|M.thermoresistible__bu      LARDAMPTFRQLFLGG-------ATGIDLERRAYVVRKRAEHELGTKGPG
MAB_0091|M.abscessus_ATCC_1997      LARDAMPTFRQLFIAG-------ASGIDLERRVYVVRKRIEHELGNQGSG
Mflv_3593|M.gilvum_PYR-GCK          TALDCMPHMAQLFVAAPERDGKRPGGIELDRRVYPLRKRAE---------
Mvan_2822|M.vanbaalenii_PYR-1       TALSCMPHMAQLFVAAPELNGARPGGIDLDRRVYPLRKRAE---------
MSMEG_3225|M.smegmatis_MC2_155      TALGCMPYMAQFFVTAPETGGARPGGVDLDRLVYPVRKRAE---------
                                     : ..** : *.*: .       . .: *:*  * :*** *         

Mb3889c|M.bovis_AF2122/97           QDGPGRETVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVH
Rv3859c|M.tuberculosis_H37Rv        QDGPGRETVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVH
MLBr_00061|M.leprae_Br4923          QDGPGRETIYFPSLSSQTFVYKGMLTTPQLKAFYRDLQDERLTSALGIVH
MMAR_5413|M.marinum_M               QDGPGRETVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH
MUL_5037|M.ulcerans_Agy99           QDGPGRETVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH
MAV_0166|M.avium_104                QDGPGRETVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH
TH_2102|M.thermoresistible__bu      QDGPGRETVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERLTSALAIVH
MAB_0091|M.abscessus_ATCC_1997      RGSLGEETVYFPSLSGRTFVYKGMLTTPQLRAFYLDLQDERVESALGIVH
Mflv_3593|M.gilvum_PYR-GCK          -----QTGVYFPSLSSRTMVYKGMLTTMQLPQYFPDLRDERCISAIAIVH
Mvan_2822|M.vanbaalenii_PYR-1       -----RAGVYFPSLSSRTMVYKGMLTTMQLPQYFSDLRDERCISAIAIVH
MSMEG_3225|M.smegmatis_MC2_155      -----REDVYFPTLSSRTMVYKGMLTTMQLPQYFLDLRDERCQSAIAIVH
                                         .  :***:**.:*:******** **  :: **:*:*  **:.***

Mb3889c|M.bovis_AF2122/97           SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGS
Rv3859c|M.tuberculosis_H37Rv        SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGS
MLBr_00061|M.leprae_Br4923          SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALMKTDIFGS
MMAR_5413|M.marinum_M               SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT
MUL_5037|M.ulcerans_Agy99           SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT
MAV_0166|M.avium_104                SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT
TH_2102|M.thermoresistible__bu      SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDLFG-
MAB_0091|M.abscessus_ATCC_1997      SRFSTNTFPSWPLAHPYRRVAHNGEINTVAGNENWMRAREALIKTDVFGD
Mflv_3593|M.gilvum_PYR-GCK          SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAMLASAHIP-
Mvan_2822|M.vanbaalenii_PYR-1       SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAMLASAKIP-
MSMEG_3225|M.smegmatis_MC2_155      SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAKLASPLIP-
                                    ****************:* :********* **.* *:**** : :  :  

Mb3889c|M.bovis_AF2122/97           AADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH
Rv3859c|M.tuberculosis_H37Rv        AADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH
MLBr_00061|M.leprae_Br4923          KADMEKLFPICTPGASDTARFDEALELLHLGGRSLVHAVLMMIPEAWERH
MMAR_5413|M.marinum_M               EANVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH
MUL_5037|M.ulcerans_Agy99           EANVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH
MAV_0166|M.avium_104                EADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH
TH_2102|M.thermoresistible__bu      GQDLEKVAPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWEQH
MAB_0091|M.abscessus_ATCC_1997      PAQLEKIFPICTRGASDTARFDEALELLHLGGRPLHHAVLMMIPEAWERH
Mflv_3593|M.gilvum_PYR-GCK          -GDLSRLSPICTPDASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENS
Mvan_2822|M.vanbaalenii_PYR-1       -GDLTRLSPICTPDASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENN
MSMEG_3225|M.smegmatis_MC2_155      -GDLSRLSPICSPEASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENA
                                      :: :: ***:  ***:* ***.*********.* ************. 

Mb3889c|M.bovis_AF2122/97           ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIW
Rv3859c|M.tuberculosis_H37Rv        ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIW
MLBr_00061|M.leprae_Br4923          ESMDPARRAFYQYHASLMEPWDGPASMTFTDGVVVGAVLDRNGLRPSRIW
MMAR_5413|M.marinum_M               ASMDPSRRAFYQYHSSLMEPWDGPASMTFTDGTIIGAVLDRNGLRPSRIW
MUL_5037|M.ulcerans_Agy99           ASMDPSRRAFYQYHSSLMEPWDGPASMTFTDGTMVGAVLDRNGLRPSRIW
MAV_0166|M.avium_104                ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVIGAVLDRNGLRPSRIW
TH_2102|M.thermoresistible__bu      ESMDPARRAFYEFHDSLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIW
MAB_0091|M.abscessus_ATCC_1997      ENMSAELRSFYEFHASLMEPWDGPASVCFTDGTIVGAVLDRNGLRPSRVW
Mflv_3593|M.gilvum_PYR-GCK          TTMEPHERAFWQFHASLMEPWDGPACVTFTDGTLVGAVLDRNGLRPGRWW
Mvan_2822|M.vanbaalenii_PYR-1       TTMGDAERAFWQFHASLMEPWDGPACVTFTDGTLVGAVLDRNGLRPGRWW
MSMEG_3225|M.smegmatis_MC2_155      TTMGAAERAFWQFHASLMEPWDGPACVTFTDGTVVGAVLDRNGLRPGRWW
                                     .*    *:*:::* **********.: ****.::***********.* *

Mb3889c|M.bovis_AF2122/97           VTDDGLVVMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEI
Rv3859c|M.tuberculosis_H37Rv        VTDDGLVVMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEI
MLBr_00061|M.leprae_Br4923          ITDAGLVVMASEAGVLDLDPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEI
MMAR_5413|M.marinum_M               VTEDGLVVMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEEI
MUL_5037|M.ulcerans_Agy99           VTEDGLVVMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEAI
MAV_0166|M.avium_104                VTEDGLVVMASEAGVLDLDPATVVRRMRLQPGRMFLVDTAQGRIVSDEEI
TH_2102|M.thermoresistible__bu      VTADGLVVMASEAGVLNLDPATVVRKMRLQPGRMFLVDTAQGRIIDDEEI
MAB_0091|M.abscessus_ATCC_1997      VTNDGLVVMASEAGVLDLDPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEV
Mflv_3593|M.gilvum_PYR-GCK          RTLDDRLILASESGVLDVPSSEIVAKGRLQPGKMLLVDTAAGRIVSDDEI
Mvan_2822|M.vanbaalenii_PYR-1       RTIDDRIILASETGVLDVPSAEIVAKGRLQPGKMFLVDTAAGRIVSDDEV
MSMEG_3225|M.smegmatis_MC2_155      RTVDDRVILASEAGVLDVPSGEIVAKGRLQPGKMLLIDTAAGRIVPDDEI
                                     *  . :::***:***:: .. :* : *****:*:*:**: ***: *: :

Mb3889c|M.bovis_AF2122/97           KADLAAEHPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEE
Rv3859c|M.tuberculosis_H37Rv        KADLAAEHPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEE
MLBr_00061|M.leprae_Br4923          KAKLAAEHPYQEWLDKGLVPIDELPAGKYVRMPHHRLVMRQLAFGYTYEE
MMAR_5413|M.marinum_M               KAELAAEHPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEE
MUL_5037|M.ulcerans_Agy99           KAELAAEHPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEE
MAV_0166|M.avium_104                KAELAAEHPYQEWLDRNLVPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEE
TH_2102|M.thermoresistible__bu      KAELAAEHPYQEWLDAGLFPLDELPQGDYQRMPHHRVVLRQRVFGYTSEE
MAB_0091|M.abscessus_ATCC_1997      KAELAAAEPYQRWLEEGLVRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEE
Mflv_3593|M.gilvum_PYR-GCK          KQELSAAQPYGEWLHSGLLELTTLPDRGHIQPNHESVVRRQVSFGYTEEE
Mvan_2822|M.vanbaalenii_PYR-1       KEKLAHAEPYGEWLHSGLLELNALPDRARAQPNHESVVRRQISFGYTEED
MSMEG_3225|M.smegmatis_MC2_155      KAQLSAAEPYEEWLHAGLLDLKTLPERGVAKPNHDSVVRRQIAFGYTEEE
                                    * .*:  .** .**. .*. :  **     :  *. :* **  **** *:

Mb3889c|M.bovis_AF2122/97           LNLLVAPMARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPP
Rv3859c|M.tuberculosis_H37Rv        LNLLVAPMARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPP
MLBr_00061|M.leprae_Br4923          LNLLVAPMVRAGSEPIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPP
MMAR_5413|M.marinum_M               LNLLVAPMVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPP
MUL_5037|M.ulcerans_Agy99           LNLLVAPMVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPP
MAV_0166|M.avium_104                LNLLVAPMVRTGAEPIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPP
TH_2102|M.thermoresistible__bu      LNLIVGPMARTGAEPLGSMGTDTPIAVLSQRSRLLFDYFQQMFAQVTNPP
MAB_0091|M.abscessus_ATCC_1997      INLLVAPMARTGAEALGSMGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPP
Mflv_3593|M.gilvum_PYR-GCK          LRILLAPMAASGAEPLGSMGTDTPAAVLSQRSKLLYDYFVELFAQVTNPP
Mvan_2822|M.vanbaalenii_PYR-1       LRILLTPMAASGVEPLGSMGTDTPPAVLSQRSKLLYDYFVELFAQVTNPP
MSMEG_3225|M.smegmatis_MC2_155      LRVLLTPMAASGNEPLGSMGTDTPTAVLSSRSRLLYDYFVELFAQVTNPP
                                    :.::: **.  * *.:****:*** **** *.::*:*** ::********

Mb3889c|M.bovis_AF2122/97           LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVS
Rv3859c|M.tuberculosis_H37Rv        LDAIREEVVTSLQGTTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVS
MLBr_00061|M.leprae_Br4923          LDAIREEVVTSLQGTTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVN
MMAR_5413|M.marinum_M               LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLIN
MUL_5037|M.ulcerans_Agy99           LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLIN
MAV_0166|M.avium_104                LDAIREEVVTSLQGTTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVN
TH_2102|M.thermoresistible__bu      LDAIREEVITSLQGVIGPEGDLLNPGPESCRQIVLPQPILRNHELAKLIN
MAB_0091|M.abscessus_ATCC_1997      LDAIREEVVTSLGGVIGPEGDLLHPTAESCHQILLPQPVLHNDELDKLIH
Mflv_3593|M.gilvum_PYR-GCK          LDAIREEIVTSMARVMGPEQNLLEPGAASCRQIKLPWPVLDNDELGKIVH
Mvan_2822|M.vanbaalenii_PYR-1       LDAIREEVVTSMARIMGPEQNLLEPSAASCRQIKLTWPVLDNDELNKIVH
MSMEG_3225|M.smegmatis_MC2_155      LDAIREEVVTSMARVMGPEENLLEPTAASCRQIVLRAPVIDNDDLGKIVH
                                    *******::**:    * * :** *   **:** *  *:: * :* *:: 

Mb3889c|M.bovis_AF2122/97           LDPNDKVNGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADG
Rv3859c|M.tuberculosis_H37Rv        LDPNDKVNGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADG
MLBr_00061|M.leprae_Br4923          LDPADEVNGRPHGMRSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGG
MMAR_5413|M.marinum_M               LDPETVINGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADG
MUL_5037|M.ulcerans_Agy99           LDPETVINGRPHGLKSKVVRCLYPVAEGGSGLAAALNEVRAQASAAIADG
MAV_0166|M.avium_104                LNPDDEVNGRPHGMRSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADG
TH_2102|M.thermoresistible__bu      VDPDHEVRGRKHGMRAAVVRCLFPVNRGGQGLKEALDRVRAKVSAAIREG
MAB_0091|M.abscessus_ATCC_1997      LDPADTVNGRAHGFSSRVIRCLYPVAEGGAGLRTALESVRAEVSAAIAGG
Mflv_3593|M.gilvum_PYR-GCK          INDD----GEHPGLRTAVLRALYDVERGGEGLADALEDLRLRACEAIAKG
Mvan_2822|M.vanbaalenii_PYR-1       INDD----GEQPGLRTTVLRALYNVERGGEGLAEAIEDLQLRASDAIAKG
MSMEG_3225|M.smegmatis_MC2_155      INDD----GEHPGLRATVLRALYDVERGGEGLAEALDDLRRRASEAIADG
                                    ::      *.  *: : *: .*: *  .* **  *:  ::  .. **  *

Mb3889c|M.bovis_AF2122/97           ARIIILSDRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAR
Rv3859c|M.tuberculosis_H37Rv        ARIIILSDRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAR
MLBr_00061|M.leprae_Br4923          ARVIILSDRNSDEQMAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAR
MMAR_5413|M.marinum_M               ARIIVLSDRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAR
MUL_5037|M.ulcerans_Agy99           ARIIVLSDRESDERMAPIPALLAVAGVHHHLVRERTRTKVGLVVESGDAR
MAV_0166|M.avium_104                ARVIILSDRESDEKMAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAR
TH_2102|M.thermoresistible__bu      ARIIVLSDRESDEQLAPIPSLLSVAAVHHHLVRDRTRTQVGLVVEAGDAR
MAB_0091|M.abscessus_ATCC_1997      AQVIILSDRESDDLMAPIPSLLAVAAVHHHLVRERSRTKVGLVVEAGDAR
Mflv_3593|M.gilvum_PYR-GCK          ARTLVISDRDSDHTKAPVPSLLAVSAVHHHLVGTKQRTSVALVVESGDAR
Mvan_2822|M.vanbaalenii_PYR-1       AHTLVISDRDSDHTKAPVPSLLAVSAVHHHLVRTKKRTTVALVVESGDAR
MSMEG_3225|M.smegmatis_MC2_155      KRILVLSDRDSDHTRAPIPSLLAVSAVHHHLVRTKERTKVALVVESGDAR
                                     : :::***:**.  **:*:**:*:.******  : ** *.****:****

Mb3889c|M.bovis_AF2122/97           EVHHMAALVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAA
Rv3859c|M.tuberculosis_H37Rv        EVHHMAALVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAA
MLBr_00061|M.leprae_Br4923          EVHHMAALIGFGAAAVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKAT
MMAR_5413|M.marinum_M               EVHHMAMLLGCGAAAVNPYLAFESIEDMLDRGVIDGIDRNTALSNYVKAA
MUL_5037|M.ulcerans_Agy99           EVHHMAMLLGCGAAAVNPYLAFASIEDMLDRGVIDGIDRNTALSNYVKAA
MAV_0166|M.avium_104                EVHHMAALVGFGAAAINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAA
TH_2102|M.thermoresistible__bu      EVHHMAALIGFGASAINPYLAFESIEDMLDRNLLEGLDRETALNNYIKAA
MAB_0091|M.abscessus_ATCC_1997      EVHHVAALVGFGAAAVNPYMAFESIEDLIDRGVITGVDRDKAIRNYIKAA
Mflv_3593|M.gilvum_PYR-GCK          EVHHIAMLIGFGAAAVNPYLAFESIEDLIREGELTGIEPSTAVRNYLKAL
Mvan_2822|M.vanbaalenii_PYR-1       EVHHIAMLIGFGAAAVNPYLAFESIEDLIREGELTGVDAATAVRNYLKAL
MSMEG_3225|M.smegmatis_MC2_155      EVHHIALLIGFGAAAVNPYLAFESIEDLIREGELTGIEPAAAVRNYIKAL
                                    ****:* *:* **:*:***:.* ***::: .. : *::   *: **:** 

Mb3889c|M.bovis_AF2122/97           GKGVLKVMSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGIT
Rv3859c|M.tuberculosis_H37Rv        GKGVLKVMSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGIT
MLBr_00061|M.leprae_Br4923          GQGVLKIMSKMGISTLASYVGAQLFQAVGISEDVLDEYFSGLSCPTGGIT
MMAR_5413|M.marinum_M               GKGVLKVMSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGIT
MUL_5037|M.ulcerans_Agy99           GKGVLKVMSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGIT
MAV_0166|M.avium_104                GKGVLKVMSKMGISTLASYTGAQLFQAVGISEDVLDEYFTGLSCPIGGIT
TH_2102|M.thermoresistible__bu      GKGVLKVMSKMGISTLRSYTGAQLFQAIGISQEVLDEYFTGLSCPTGGID
MAB_0091|M.abscessus_ATCC_1997      GKGVLKVMSKMGISTLASYTGAQLFQAIGLSQELLDEYFTGLACPTGGIG
Mflv_3593|M.gilvum_PYR-GCK          GKGVMKVMSKMGISTVASYTAAQAFEAIGIDRDVIDEYFTGTPTQLGGIG
Mvan_2822|M.vanbaalenii_PYR-1       GKGVMKVMSKMGISTVASYTAAQAFEAVGIDKAVIDEYFTGTPTQLGGIG
MSMEG_3225|M.smegmatis_MC2_155      CKGVVKVMSKMGISTVASYTAAQVFEAIGLDRGVIDEYFTGTTSQLGGVG
                                     :**:*:********: **..** *:*:*:.. :::***:* .   **: 

Mb3889c|M.bovis_AF2122/97           LDDIAADVAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV
Rv3859c|M.tuberculosis_H37Rv        LDDIAADVAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV
MLBr_00061|M.leprae_Br4923          LDDIAAEVAVRHRVAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV
MMAR_5413|M.marinum_M               LDDIAADVATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV
MUL_5037|M.ulcerans_Agy99           LDDIAADVASRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV
MAV_0166|M.avium_104                LDDIAADVAARHALAYLDRPNERAHRELEVGGEYQWRREGEYHLFNPETV
TH_2102|M.thermoresistible__bu      LDDIAADVARRHELAYLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTV
MAB_0091|M.abscessus_ATCC_1997      LDEIAADVASRHNLAFLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTV
Mflv_3593|M.gilvum_PYR-GCK          LDVIAEEVKLRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV
Mvan_2822|M.vanbaalenii_PYR-1       LDVIAEEVKLRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV
MSMEG_3225|M.smegmatis_MC2_155      LDVLADEVKMRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV
                                    ** :* :*  **  *: :.* * .**.******* :***** ***.*:.*

Mb3889c|M.bovis_AF2122/97           FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDE
Rv3859c|M.tuberculosis_H37Rv        FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDE
MLBr_00061|M.leprae_Br4923          FKLQHATRSGQYKIFKEYTRLVDDQSERMASLRGLLKFRSGVRTPVPLDE
MMAR_5413|M.marinum_M               FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDE
MUL_5037|M.ulcerans_Agy99           FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDE
MAV_0166|M.avium_104                FKLQHATRTGQYKIFKDYTRLVDDQSERMASLRGLLKFRAGVRPPVPLEE
TH_2102|M.thermoresistible__bu      FKLQHSTRTGQYEIFKEYTRLVDDQSERMASLRGLLKFKEGVRPPVPIEE
MAB_0091|M.abscessus_ATCC_1997      FKLQHSTRTGQYSVFKEYTQLVDDQSERMASLRGLLKFKTGVRPPVPLDE
Mflv_3593|M.gilvum_PYR-GCK          FLLQHSTRTGRYEVFKQYSDEVDRLGRDGGALRGLFDFKKGLREPVPLDE
Mvan_2822|M.vanbaalenii_PYR-1       FLLQHSTRTGRYEVFEQYSEEVNRLAREGGALRGLFEFKTGLRPPVPLHE
MSMEG_3225|M.smegmatis_MC2_155      FLLQHSTRTGRRDIFAKYSEEVDRLSRKGGTLRGLFELKTGVRPPVPLEE
                                    * ***:**:*: .:* .*:  *:  ..  .:****:.:: *:* *:*:.*

Mb3889c|M.bovis_AF2122/97           VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVK
Rv3859c|M.tuberculosis_H37Rv        VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVK
MLBr_00061|M.leprae_Br4923          VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVN
MMAR_5413|M.marinum_M               VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVG
MUL_5037|M.ulcerans_Agy99           VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVG
MAV_0166|M.avium_104                VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVK
TH_2102|M.thermoresistible__bu      VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNSGEGGEHVS
MAB_0091|M.abscessus_ATCC_1997      VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDPR
Mflv_3593|M.gilvum_PYR-GCK          VESADEIVKRFNTGAMSYGSISAEAHETMAIAMNALGGRSNSGEGGEDVD
Mvan_2822|M.vanbaalenii_PYR-1       VESVDSIVTRFNTGAMSYGSISAEAHETMAVAMNNLGGRSNSGEGGEDVE
MSMEG_3225|M.smegmatis_MC2_155      VEPVESIVTRFNTGAMSYGSISAEAHETMAIAMNKLGGRSNSGEGGEDVD
                                    **....**.**.*****:**********:*:*** **.***.*****.  

Mb3889c|M.bovis_AF2122/97           RFDRDPNGDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGG
Rv3859c|M.tuberculosis_H37Rv        RFDRDPNGDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGG
MLBr_00061|M.leprae_Br4923          RFEPDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG
MMAR_5413|M.marinum_M               RFEQDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG
MUL_5037|M.ulcerans_Agy99           RFEQDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG
MAV_0166|M.avium_104                RFDRDPDGSWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGG
TH_2102|M.thermoresistible__bu      RFDPDDNGDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGG
MAB_0091|M.abscessus_ATCC_1997      RFTPDENGDWRRSAIKQVASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGG
Mflv_3593|M.gilvum_PYR-GCK          RLYDPK----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG
Mvan_2822|M.vanbaalenii_PYR-1       RLYDPK----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG
MSMEG_3225|M.smegmatis_MC2_155      RLYDPR----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG
                                    *:        ****:*****.******.** *.**:**************

Mb3889c|M.bovis_AF2122/97           QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
Rv3859c|M.tuberculosis_H37Rv        QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
MLBr_00061|M.leprae_Br4923          QLPGRKVYPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
MMAR_5413|M.marinum_M               QLPGHKVYPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
MUL_5037|M.ulcerans_Agy99           QLPGHKVYPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
MAV_0166|M.avium_104                QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
TH_2102|M.thermoresistible__bu      QLPGNKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP
MAB_0091|M.abscessus_ATCC_1997      QLPAHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNP
Mflv_3593|M.gilvum_PYR-GCK          QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANA
Mvan_2822|M.vanbaalenii_PYR-1       QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANA
MSMEG_3225|M.smegmatis_MC2_155      QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANS
                                    ***. **** :*:.*:*******************************:*.

Mb3889c|M.bovis_AF2122/97           SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG
Rv3859c|M.tuberculosis_H37Rv        SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG
MLBr_00061|M.leprae_Br4923          SARVHVKLVSENGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSG
MMAR_5413|M.marinum_M               SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG
MUL_5037|M.ulcerans_Agy99           SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG
MAV_0166|M.avium_104                AARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG
TH_2102|M.thermoresistible__bu      QARVHVKLVSEAGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAG
MAB_0091|M.abscessus_ATCC_1997      QARIHVKLVSENGVGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAG
Mflv_3593|M.gilvum_PYR-GCK          DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGYDGGTGAAPLTSLKHAG
Mvan_2822|M.vanbaalenii_PYR-1       DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGYDGGTGAAPLTSLKHAG
MSMEG_3225|M.smegmatis_MC2_155      DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGHDGGTGAAPLTSLKHAG
                                     **:******. ******:***********:**:******:****:**:*

Mb3889c|M.bovis_AF2122/97           APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGF
Rv3859c|M.tuberculosis_H37Rv        APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGF
MLBr_00061|M.leprae_Br4923          APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGF
MMAR_5413|M.marinum_M               APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGF
MUL_5037|M.ulcerans_Agy99           APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGF
MAV_0166|M.avium_104                APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGF
TH_2102|M.thermoresistible__bu      APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGF
MAB_0091|M.abscessus_ATCC_1997      APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGF
Mflv_3593|M.gilvum_PYR-GCK          APWEIGLADTQQTMVLNGLRDRITVQCDGGMRTARDVMVAMLLGAEEYGF
Mvan_2822|M.vanbaalenii_PYR-1       APWEIGLADTQQTLMLNGLRDRITVQCDGGMRTARDVMVAMLLGAEEYGF
MSMEG_3225|M.smegmatis_MC2_155      APWEIGLADTQQTLVLNGLRDRITVQCDGGLRTARDVVVAMLLGAEEYGF
                                    ****:***:****::********.** ** ::*.***::* ***.**:**

Mb3889c|M.bovis_AF2122/97           ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFI
Rv3859c|M.tuberculosis_H37Rv        ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFI
MLBr_00061|M.leprae_Br4923          ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFI
MMAR_5413|M.marinum_M               ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFI
MUL_5037|M.ulcerans_Agy99           ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFI
MAV_0166|M.avium_104                ATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFI
TH_2102|M.thermoresistible__bu      ATAPLVVSGCVMMRVCHLDTCPVGVATQNPVLRQRFTGKPEFVENFFLFI
MAB_0091|M.abscessus_ATCC_1997      ATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFI
Mflv_3593|M.gilvum_PYR-GCK          ATAPLVVSGCIMMRVCHLDTCPVGVATQNPQLRARFNGKPEFVENFFRFI
Mvan_2822|M.vanbaalenii_PYR-1       ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENYFRFI
MSMEG_3225|M.smegmatis_MC2_155      ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENFFTFI
                                    *******:**:******************* ** **.********:* **

Mb3889c|M.bovis_AF2122/97           AEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPE
Rv3859c|M.tuberculosis_H37Rv        AEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPE
MLBr_00061|M.leprae_Br4923          AEEVREYMAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPE
MMAR_5413|M.marinum_M               AEEVREYMAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPE
MUL_5037|M.ulcerans_Agy99           AEEVREYMAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPE
MAV_0166|M.avium_104                AEEVREYMAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPE
TH_2102|M.thermoresistible__bu      AEEVREYMAKMGFRTVNEMVGQVGMLDTTRAAEHWKAHKLDLSPVLHQPE
MAB_0091|M.abscessus_ATCC_1997      AEEVRELMAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPE
Mflv_3593|M.gilvum_PYR-GCK          AEDIRKYLAELGFRSIDEAVGHAEMLDTAAGVAHWKSRGLDLSPLFAVPD
Mvan_2822|M.vanbaalenii_PYR-1       AEDIRKYLAELGFRSIDEAVGRAELLDTDMGVAHWKSKGLDLSPIFAVPS
MSMEG_3225|M.smegmatis_MC2_155      AEDIRRYLAELGFRSIDEAVGHAELLDTAEGVAHWKTRGLDLDPIFAVPT
                                    **::*. :*::***:.:* **:.  **      ***:  :** *::  * 

Mb3889c|M.bovis_AF2122/97           SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN
Rv3859c|M.tuberculosis_H37Rv        SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN
MLBr_00061|M.leprae_Br4923          SAFMN--QDLYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGN
MMAR_5413|M.marinum_M               SAFMN--QDLYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISN
MUL_5037|M.ulcerans_Agy99           SAFMN--QGLYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISN
MAV_0166|M.avium_104                SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISN
TH_2102|M.thermoresistible__bu      SAFMN--QDLYCSSRQDHGLDKALDQQLITMCREALDNGTPVRFSTTIAN
MAB_0091|M.abscessus_ATCC_1997      SAFMN--QDLYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITN
Mflv_3593|M.gilvum_PYR-GCK          TASQ-----RRRTRDQDHGLDQALDRTLIQLAEGALEDAHPVRLELPVRN
Mvan_2822|M.vanbaalenii_PYR-1       NAHTGEPAARRRVRDQYHALDQALDQTLIQLAEGALEDAHPVRLELPIRN
MSMEG_3225|M.smegmatis_MC2_155      DAHGAKLTQRRKLREQDHGLDQALDRTLIQLAEGALEDAHPVRLELPVRN
                                     *             * *.*::.**: ** :.. **: . **::   : *

Mb3889c|M.bovis_AF2122/97           VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR
Rv3859c|M.tuberculosis_H37Rv        VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR
MLBr_00061|M.leprae_Br4923          VNRTVGTMLGHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLR
MMAR_5413|M.marinum_M               VNRTVGTMLGHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLR
MUL_5037|M.ulcerans_Agy99           VNRTVGTMLGHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLR
MAV_0166|M.avium_104                VNRTVGTMLGHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLR
TH_2102|M.thermoresistible__bu      VNRTVGTMLGHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLR
MAB_0091|M.abscessus_ATCC_1997      VNRTVGTMLGHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLR
Mflv_3593|M.gilvum_PYR-GCK          VNRTVGTLLGSEVTRRYGAQGLPEDTIHIALTGSAGQSLGAFLPPGITLE
Mvan_2822|M.vanbaalenii_PYR-1       VNRTVGTLLGSEVTRRYGAQGLPDDSIHVTLTGSAGQSIGAFLPPGITLE
MSMEG_3225|M.smegmatis_MC2_155      VNRTVGTLLGSEVTRRYGAAGLPDDTIHVTLTGSAGQSIGAFLPPGITLE
                                    *******:** *:*: **. ***:.:*.::: ****:*:***:* ****.

Mb3889c|M.bovis_AF2122/97           VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE
Rv3859c|M.tuberculosis_H37Rv        VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE
MLBr_00061|M.leprae_Br4923          VYGDANDYVGKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGE
MMAR_5413|M.marinum_M               IYGDANDYVGKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGE
MUL_5037|M.ulcerans_Agy99           IYGDANDYVGKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGE
MAV_0166|M.avium_104                VYGDANDYVGKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGE
TH_2102|M.thermoresistible__bu      VYGDANDYVGKGLSGGRIVVRPPDNVPESFVAEDNIIAGNVILFGATSGE
MAB_0091|M.abscessus_ATCC_1997      LFGDANDYVGKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGE
Mflv_3593|M.gilvum_PYR-GCK          LVGDANDYVGKGLSGGKIIVKPQDDV--LFLAEDNVIAGNTLLFGATSGE
Mvan_2822|M.vanbaalenii_PYR-1       LVGDANDYVGKGLSGGKIIVKPQDDV--LFLPEDNVIAGNTLLYGATSGE
MSMEG_3225|M.smegmatis_MC2_155      LVGDANDYVGKGLSGGRVVVRPPDDV--LFLPEDNVIAGNTLMYGATSGE
                                    : **************:::*:*  ..   ::.*.*:*.**.:::******

Mb3889c|M.bovis_AF2122/97           VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA
Rv3859c|M.tuberculosis_H37Rv        VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA
MLBr_00061|M.leprae_Br4923          VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAA
MMAR_5413|M.marinum_M               VFLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGQTGRNFAA
MUL_5037|M.ulcerans_Agy99           VFLRGVVGERFAVRNSGAHVVVEGVGDHGCEYMTGGRVVILGQTGRNFAA
MAV_0166|M.avium_104                AYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAA
TH_2102|M.thermoresistible__bu      VFLRGQVGERFAVRNSGALAVVEGVGDHGCEYMTGGRVVILGPVGRNFAA
MAB_0091|M.abscessus_ATCC_1997      AFLNGVVGERFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAA
Mflv_3593|M.gilvum_PYR-GCK          LYLRGRVGERFAARNSGALTVVEGVGDHACEYMTGGRVVVLGKVGRNMAA
Mvan_2822|M.vanbaalenii_PYR-1       LYLRGRVGERFAARNSGALAVVEGVGDHACEYMTGGRVVVLGKIGRNMAA
MSMEG_3225|M.smegmatis_MC2_155      VYLRGRVGERFCARNSGALAVVEGVGDHACEYMTGGRVVILGKTGRNMAA
                                     :*.* *****..***** .********.******* **:**  ***:**

Mb3889c|M.bovis_AF2122/97           GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD
Rv3859c|M.tuberculosis_H37Rv        GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD
MLBr_00061|M.leprae_Br4923          GMSGGEAYVYDSDGELPANLNFEMVELEPLDFDDAAWLYATIQAHVDATD
MMAR_5413|M.marinum_M               GMSGGIAYVYDPDGELPDNLNTEMVDVETLDDDDSEFVHGIVQAHVDATD
MUL_5037|M.ulcerans_Agy99           GMSGGIAYVYDPDGELPDNLNTEMVDVETLDDDDSEFVHGIVQAHVDATD
MAV_0166|M.avium_104                GMSGGVAYIYDPPGEFPQHLNAEMVELESLDDDDIEWLHGMIQAHVDATD
TH_2102|M.thermoresistible__bu      GMSGGIAYVYDPDGVLPGRLNREMVELESLDDEDREWLRGFIAAHVDATD
MAB_0091|M.abscessus_ATCC_1997      GMSGGVAYVYDPDKRLMDNLNDEMVDLDALDPDDQQVLRSLIEKHVAATD
Mflv_3593|M.gilvum_PYR-GCK          GMSGGIAFVLGLD---PRRVNTAMVELQRLEPEDLAWLHGVVGQHARYTG
Mvan_2822|M.vanbaalenii_PYR-1       GMSGGIAFVLGLD---PSRVNTDMVELQALEPEDLAWLRDVVAQHAHYTG
MSMEG_3225|M.smegmatis_MC2_155      GMSGGIAFVLGLD---PARVNTEMVQLQRLDPEDLEWLHHVVTDHVRYTG
                                    ***** *:: .       .:*  **::: *: :*   :   :  *.  *.

Mb3889c|M.bovis_AF2122/97           SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA
Rv3859c|M.tuberculosis_H37Rv        SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA
MLBr_00061|M.leprae_Br4923          SAVGQRILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVDVNKVIMEP
MMAR_5413|M.marinum_M               SAVGQRVLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVDIDKAIMAA
MUL_5037|M.ulcerans_Agy99           SAVGQRVLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVDIDKAIMAA
MAV_0166|M.avium_104                SAVGQRILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGDVDKAIMAA
TH_2102|M.thermoresistible__bu      SAIGQRILNDWDEHVTHFAKVMPRDYKRVLTAIAEAEASGADVDEAIMAA
MAB_0091|M.abscessus_ATCC_1997      SAVGQRILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGDVNEAIMAA
Mflv_3593|M.gilvum_PYR-GCK          STVATSLLSDWPRRSAQFTKIMPRDYQRVLQATRMAKAEGRDVDSAIMEA
Mvan_2822|M.vanbaalenii_PYR-1       STVATSVLSDWPRRSAQFTKVMPRDFQRVLQATRMAKAEGRDVDTAIMEA
MSMEG_3225|M.smegmatis_MC2_155      STLGTSLLSDWPRRSAQFTKIMPTDYQRVLQATRMAKAEGRDVDSAIMEA
                                    *::.  :* .*  :   *.*:** *::*** *   *:  * *:: .** .

Mb3889c|M.bovis_AF2122/97           AHG
Rv3859c|M.tuberculosis_H37Rv        AHG
MLBr_00061|M.leprae_Br4923          AHG
MMAR_5413|M.marinum_M               SHG
MUL_5037|M.ulcerans_Agy99           SHG
MAV_0166|M.avium_104                AHG
TH_2102|M.thermoresistible__bu      ANG
MAB_0091|M.abscessus_ATCC_1997      ARG
Mflv_3593|M.gilvum_PYR-GCK          SRG
Mvan_2822|M.vanbaalenii_PYR-1       SRG
MSMEG_3225|M.smegmatis_MC2_155      SRG
                                    :.*