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VLYSALPDAQGLYDPQNEADSCGVAMIADIQGRKSHRIVSDGLIALENLEHRGAAGAEASSGDGAGILIQ LPVELLREVVDFELPAPTADGDNTFAAGVCFLPQDPVARSAARERIEAIAVEEGLEVLGWRKLPVDPDGA GIGATALGCMPYMAQFFVTAPETGGARPGGVDLDRLVYPVRKRAEREDVYFPTLSSRTMVYKGMLTTMQL PQYFLDLRDERCQSAIAIVHSRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAKLASPLIPG DLSRLSPICSPEASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENATTMGAAERAFWQFHASLMEPWD GPACVTFTDGTVVGAVLDRNGLRPGRWWRTVDDRVILASEAGVLDVPSGEIVAKGRLQPGKMLLIDTAAG RIVPDDEIKAQLSAAEPYEEWLHAGLLDLKTLPERGVAKPNHDSVVRRQIAFGYTEEELRVLLTPMAASG NEPLGSMGTDTPTAVLSSRSRLLYDYFVELFAQVTNPPLDAIREEVVTSMARVMGPEENLLEPTAASCRQ IVLRAPVIDNDDLGKIVHINDDGEHPGLRATVLRALYDVERGGEGLAEALDDLRRRASEAIADGKRILVL SDRDSDHTRAPIPSLLAVSAVHHHLVRTKERTKVALVVESGDAREVHHIALLIGFGAAAVNPYLAFESIE DLIREGELTGIEPAAAVRNYIKALCKGVVKVMSKMGISTVASYTAAQVFEAIGLDRGVIDEYFTGTTSQL GGVGLDVLADEVKMRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVVFLLQHSTRTGRRDIFA KYSEEVDRLSRKGGTLRGLFELKTGVRPPVPLEEVEPVESIVTRFNTGAMSYGSISAEAHETMAIAMNKL GGRSNSGEGGEDVDRLYDPRRRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGGQLPGYKVYPN IAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANSDARIHVKLVSSVGVGTVAAGVSKAHADVVL ISGHDGGTGAAPLTSLKHAGAPWEIGLADTQQTLVLNGLRDRITVQCDGGLRTARDVVVAMLLGAEEYGF ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENFFTFIAEDIRRYLAELGFRSIDEAV GHAELLDTAEGVAHWKTRGLDLDPIFAVPTDAHGAKLTQRRKLREQDHGLDQALDRTLIQLAEGALEDAH PVRLELPVRNVNRTVGTLLGSEVTRRYGAAGLPDDTIHVTLTGSAGQSIGAFLPPGITLELVGDANDYVG KGLSGGRVVVRPPDDVLFLPEDNVIAGNTLMYGATSGEVYLRGRVGERFCARNSGALAVVEGVGDHACEY MTGGRVVILGKTGRNMAAGMSGGIAFVLGLDPARVNTEMVQLQRLDPEDLEWLHHVVTDHVRYTGSTLGT SLLSDWPRRSAQFTKIMPTDYQRVLQATRMAKAEGRDVDSAIMEASRG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3225 | - | - | 100% (1518) | ferredoxin-dependent glutamate synthase 1 |
M. smegmatis MC2 155 | MSMEG_6459 | - | 0.0 | 63.62% (1542) | ferredoxin-dependent glutamate synthase 1 |
M. smegmatis MC2 155 | MSMEG_5594 | - | 1e-35 | 33.66% (309) | ferredoxin-dependent glutamate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3889c | gltB | 0.0 | 64.18% (1541) | putative ferredoxin-dependent glutamate synthase |
M. gilvum PYR-GCK | Mflv_3593 | - | 0.0 | 86.55% (1517) | glutamate synthase (ferredoxin) |
M. tuberculosis H37Rv | Rv3859c | gltB | 0.0 | 64.18% (1541) | ferredoxin-dependent glutamate synthase |
M. leprae Br4923 | MLBr_00061 | gltB | 0.0 | 62.13% (1537) | putative ferredoxin-dependent glutamate synthase |
M. abscessus ATCC 19977 | MAB_0091 | - | 0.0 | 62.44% (1544) | putative ferredoxin-dependent glutamate synthase |
M. marinum M | MMAR_5413 | gltB | 0.0 | 63.21% (1541) | ferredoxin-dependent glutamate synthase |
M. avium 104 | MAV_0166 | - | 0.0 | 63.21% (1541) | ferredoxin-dependent glutamate synthase 1 |
M. thermoresistible (build 8) | TH_2102 | gltB | 0.0 | 64.01% (1545) | PROBABLE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE |
M. ulcerans Agy99 | MUL_5037 | gltB | 0.0 | 62.95% (1544) | ferredoxin-dependent glutamate synthase |
M. vanbaalenii PYR-1 | Mvan_2822 | - | 0.0 | 86.30% (1518) | glutamate synthase (ferredoxin) |
CLUSTAL 2.0.9 multiple sequence alignment Mb3889c|M.bovis_AF2122/97 ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN Rv3859c|M.tuberculosis_H37Rv ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN MLBr_00061|M.leprae_Br4923 ------MTAKRVGLYNPAFEHDSCGVAMVVDMYGRRTRDIVDKAITALLN MMAR_5413|M.marinum_M ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN MUL_5037|M.ulcerans_Agy99 ------MTPKRVGLYNPAFEHDSCGVAMVVDMHGRRSRDIVDKAITALLN MAV_0166|M.avium_104 ----MHMTPKRAGLYNPAFEHDACGVAMVVDMHGRRSRDIVDKAITALLN TH_2102|M.thermoresistible__bu ------MTPKAQGLYNPAFEHDACGVAMVADMYGRRSRDIVDKAITALLN MAB_0091|M.abscessus_ATCC_1997 ------MPHPATGLYNPAYEHDSCGVAMVVDMHGRRSRDIVDKAITALLN Mflv_3593|M.gilvum_PYR-GCK MSTLFSALPQPQGLYDPANESDSCGVAMVVDIQGRSSHSIVTDGLIALEH Mvan_2822|M.vanbaalenii_PYR-1 --MLFSALPDAQGLYDPGNESDSCGVAMVTDIQGRRSHSIVADGLTALEH MSMEG_3225|M.smegmatis_MC2_155 --MLYSALPDAQGLYDPQNEADSCGVAMIADIQGRKSHRIVSDGLIALEN ***:* * *:*****:.*: ** :: ** ..: ** : Mb3889c|M.bovis_AF2122/97 LEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP-----GS Rv3859c|M.tuberculosis_H37Rv LEHRGAQGAEPRSGDGAGILIQVPDEFLREAV----DFELPAP-----GS MLBr_00061|M.leprae_Br4923 LEHRGAQGAEPRSGDGAGILIQVPDAFLRAVV----DFELPAA-----SS MMAR_5413|M.marinum_M LEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP-----GS MUL_5037|M.ulcerans_Agy99 LEHRGAAGAEPRSGDGAGILIQVPDAFLREVV----DFELPAP-----GS MAV_0166|M.avium_104 LEHRGAQGAEPRSGDGAGILIQVPDAFLREVV----DFELPPE-----GS TH_2102|M.thermoresistible__bu LEHRGAQGAEPNTGDGAGILLQVPDEFLRAVVEEQGDFELPPP-----GS MAB_0091|M.abscessus_ATCC_1997 LEHRGAAGAEPNSGDGAGIMLQIPDKFFRAVLAEQGSFELPAE-----GS Mflv_3593|M.gilvum_PYR-GCK LEHRGAAGAEPNSGDGAGILIQLPVDLLRDVA----DFDLPPATGDG-NT Mvan_2822|M.vanbaalenii_PYR-1 LEHRGAAGAEPTSGDGAGILIQLPVDLLRAVT----DFALPDPTGDGANT MSMEG_3225|M.smegmatis_MC2_155 LEHRGAAGAEASSGDGAGILIQLPVELLREVV----DFELPAPTADGDNT ****** ***. :******::*:* ::* . .* ** .: Mb3889c|M.bovis_AF2122/97 YATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTD--DSSLGA Rv3859c|M.tuberculosis_H37Rv YATGIAFLPQSSKDAAAACAAVQKIAEAEGLQVLGWRSVPTD--DSSLGA MLBr_00061|M.leprae_Br4923 YATGIAFLPQSSKDAAAACAAVEKIAVAEGLHVLGWRNVPTD--ASSLGA MMAR_5413|M.marinum_M YATGIAFLPQSSKDAAAACAAVEKIAEAEGLQVLGWRNVPTD--DSSLGA MUL_5037|M.ulcerans_Agy99 YATGIAFLPQSSKDAAAACAAVEKIGEAEGLQVLGWRNVPTD--DSSLGA MAV_0166|M.avium_104 YATGIAFLPQSSKDAATACAAVEKIAEAEGLTVLGWRNVPTD--DSSLGA TH_2102|M.thermoresistible__bu YATGIAFLPQSAKDAAQACDAVEKIVEAEGLTVLGWREVPID--DSSLGA MAB_0091|M.abscessus_ATCC_1997 YASGIAFLPQGSKDAATACEAVEKIVEAEGLTVLGWREVPHD--DSSLGA Mflv_3593|M.gilvum_PYR-GCK FAAGICYLPQDPVQRDAARAAVETIAAEENLDVLGWREVPVDPAGAEIGR Mvan_2822|M.vanbaalenii_PYR-1 FAAGICFLPQDLAARESARGTVEAIAAEEGLEVLGWREMPVDPDGADLGA MSMEG_3225|M.smegmatis_MC2_155 FAAGVCFLPQDPVARSAARERIEAIAVEEGLEVLGWRKLPVDPDGAGIGA :*:*:.:***. * :: * *.* *****.:* * : :* Mb3889c|M.bovis_AF2122/97 LSRDAMPTFRQVFLAG-------ASGMALERRCYVVRKRAEHELGTKGPG Rv3859c|M.tuberculosis_H37Rv LSRDAMPTFRQVFLAG-------ASGMALERRCYVVRKRAEHELGTKGPG MLBr_00061|M.leprae_Br4923 LSRDAMPTFRQVFMAG-------ATGLTLERRAYVIRKRAEHELGTKGPG MMAR_5413|M.marinum_M LSRDAMPTFRQVFLAG-------ASDMTLERRCYVIRKRAEHELGTKGPG MUL_5037|M.ulcerans_Agy99 LSRDAMPTFRQVFLAG-------ASDMALERRCYVIRKRAEHELGTKGPG MAV_0166|M.avium_104 LSRDAMPTFRQVFMAG-------ASGMTLERRAYLVRKRAEHELGTKGPG TH_2102|M.thermoresistible__bu LARDAMPTFRQLFLGG-------ATGIDLERRAYVVRKRAEHELGTKGPG MAB_0091|M.abscessus_ATCC_1997 LARDAMPTFRQLFIAG-------ASGIDLERRVYVVRKRIEHELGNQGSG Mflv_3593|M.gilvum_PYR-GCK TALDCMPHMAQLFVAAPERDGKRPGGIELDRRVYPLRKRAE--------- Mvan_2822|M.vanbaalenii_PYR-1 TALSCMPHMAQLFVAAPELNGARPGGIDLDRRVYPLRKRAE--------- MSMEG_3225|M.smegmatis_MC2_155 TALGCMPYMAQFFVTAPETGGARPGGVDLDRLVYPVRKRAE--------- : ..** : *.*: . . .: *:* * :*** * Mb3889c|M.bovis_AF2122/97 QDGPGRETVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVH Rv3859c|M.tuberculosis_H37Rv QDGPGRETVYFPSLSGQTLVYKGMLTTPQLKAFYLDLQDERLTSALGIVH MLBr_00061|M.leprae_Br4923 QDGPGRETIYFPSLSSQTFVYKGMLTTPQLKAFYRDLQDERLTSALGIVH MMAR_5413|M.marinum_M QDGPGRETVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH MUL_5037|M.ulcerans_Agy99 QDGPGRETVYFPSLSGRTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH MAV_0166|M.avium_104 QDGPGRETVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDDRLTSALGIVH TH_2102|M.thermoresistible__bu QDGPGRETVYFPSLSGQTFVYKGMLTTPQLKAFYLDLQDERLTSALAIVH MAB_0091|M.abscessus_ATCC_1997 RGSLGEETVYFPSLSGRTFVYKGMLTTPQLRAFYLDLQDERVESALGIVH Mflv_3593|M.gilvum_PYR-GCK -----QTGVYFPSLSSRTMVYKGMLTTMQLPQYFPDLRDERCISAIAIVH Mvan_2822|M.vanbaalenii_PYR-1 -----RAGVYFPSLSSRTMVYKGMLTTMQLPQYFSDLRDERCISAIAIVH MSMEG_3225|M.smegmatis_MC2_155 -----REDVYFPTLSSRTMVYKGMLTTMQLPQYFLDLRDERCQSAIAIVH . :***:**.:*:******** ** :: **:*:* **:.*** Mb3889c|M.bovis_AF2122/97 SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGS Rv3859c|M.tuberculosis_H37Rv SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDIFGS MLBr_00061|M.leprae_Br4923 SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALMKTDIFGS MMAR_5413|M.marinum_M SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT MUL_5037|M.ulcerans_Agy99 SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT MAV_0166|M.avium_104 SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIKTDVFGT TH_2102|M.thermoresistible__bu SRFSTNTFPSWPLAHPFRRIAHNGEINTVTGNENWMRAREALIRTDLFG- MAB_0091|M.abscessus_ATCC_1997 SRFSTNTFPSWPLAHPYRRVAHNGEINTVAGNENWMRAREALIKTDVFGD Mflv_3593|M.gilvum_PYR-GCK SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAMLASAHIP- Mvan_2822|M.vanbaalenii_PYR-1 SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAMLASAKIP- MSMEG_3225|M.smegmatis_MC2_155 SRFSTNTFPSWPLAHPFRFVAHNGEINTVRGNRNRMHAREAKLASPLIP- ****************:* :********* **.* *:**** : : : Mb3889c|M.bovis_AF2122/97 AADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH Rv3859c|M.tuberculosis_H37Rv AADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH MLBr_00061|M.leprae_Br4923 KADMEKLFPICTPGASDTARFDEALELLHLGGRSLVHAVLMMIPEAWERH MMAR_5413|M.marinum_M EANVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH MUL_5037|M.ulcerans_Agy99 EANVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH MAV_0166|M.avium_104 EADVEKLFPICTPGASDTARFDEVLELLHLGGRSLAHAVLMMIPEAWERH TH_2102|M.thermoresistible__bu GQDLEKVAPICTPGASDTARFDEVLELLHLGGRSLPHAVLMMIPEAWEQH MAB_0091|M.abscessus_ATCC_1997 PAQLEKIFPICTRGASDTARFDEALELLHLGGRPLHHAVLMMIPEAWERH Mflv_3593|M.gilvum_PYR-GCK -GDLSRLSPICTPDASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENS Mvan_2822|M.vanbaalenii_PYR-1 -GDLTRLSPICTPDASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENN MSMEG_3225|M.smegmatis_MC2_155 -GDLSRLSPICSPEASDSASFDEVLELLHLGGRSLPHAVLMMIPEAWENA :: :: ***: ***:* ***.*********.* ************. Mb3889c|M.bovis_AF2122/97 ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIW Rv3859c|M.tuberculosis_H37Rv ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVVGAVLDRNGLRPSRIW MLBr_00061|M.leprae_Br4923 ESMDPARRAFYQYHASLMEPWDGPASMTFTDGVVVGAVLDRNGLRPSRIW MMAR_5413|M.marinum_M ASMDPSRRAFYQYHSSLMEPWDGPASMTFTDGTIIGAVLDRNGLRPSRIW MUL_5037|M.ulcerans_Agy99 ASMDPSRRAFYQYHSSLMEPWDGPASMTFTDGTMVGAVLDRNGLRPSRIW MAV_0166|M.avium_104 ESMDPARRAFYQYHASLMEPWDGPASMTFTDGTVIGAVLDRNGLRPSRIW TH_2102|M.thermoresistible__bu ESMDPARRAFYEFHDSLMEPWDGPASVCFTDGTVIGAVLDRNGLRPSRIW MAB_0091|M.abscessus_ATCC_1997 ENMSAELRSFYEFHASLMEPWDGPASVCFTDGTIVGAVLDRNGLRPSRVW Mflv_3593|M.gilvum_PYR-GCK TTMEPHERAFWQFHASLMEPWDGPACVTFTDGTLVGAVLDRNGLRPGRWW Mvan_2822|M.vanbaalenii_PYR-1 TTMGDAERAFWQFHASLMEPWDGPACVTFTDGTLVGAVLDRNGLRPGRWW MSMEG_3225|M.smegmatis_MC2_155 TTMGAAERAFWQFHASLMEPWDGPACVTFTDGTVVGAVLDRNGLRPGRWW .* *:*:::* **********.: ****.::***********.* * Mb3889c|M.bovis_AF2122/97 VTDDGLVVMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEI Rv3859c|M.tuberculosis_H37Rv VTDDGLVVMASEAGVLDLHPSTVVRRMRLQPGRMFLVDTAQGRIVSDEEI MLBr_00061|M.leprae_Br4923 ITDAGLVVMASEAGVLDLDPSIVVRRMRLQPGRMFLVDTAQGRIVSDEEI MMAR_5413|M.marinum_M VTEDGLVVMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEEI MUL_5037|M.ulcerans_Agy99 VTEDGLVVMASEAGVLDLDPSTVVQRMRLQPGRMFLVDTAQGRIVSDEAI MAV_0166|M.avium_104 VTEDGLVVMASEAGVLDLDPATVVRRMRLQPGRMFLVDTAQGRIVSDEEI TH_2102|M.thermoresistible__bu VTADGLVVMASEAGVLNLDPATVVRKMRLQPGRMFLVDTAQGRIIDDEEI MAB_0091|M.abscessus_ATCC_1997 VTNDGLVVMASEAGVLDLDPSTVVQRTRLQPGRMFLVDTTQGRIVSDEEV Mflv_3593|M.gilvum_PYR-GCK RTLDDRLILASESGVLDVPSSEIVAKGRLQPGKMLLVDTAAGRIVSDDEI Mvan_2822|M.vanbaalenii_PYR-1 RTIDDRIILASETGVLDVPSAEIVAKGRLQPGKMFLVDTAAGRIVSDDEV MSMEG_3225|M.smegmatis_MC2_155 RTVDDRVILASEAGVLDVPSGEIVAKGRLQPGKMLLIDTAAGRIVPDDEI * . :::***:***:: .. :* : *****:*:*:**: ***: *: : Mb3889c|M.bovis_AF2122/97 KADLAAEHPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEE Rv3859c|M.tuberculosis_H37Rv KADLAAEHPYQEWLDNGLVPLDELPEGKDVRMPHHRIVMRQLAFGYTYEE MLBr_00061|M.leprae_Br4923 KAKLAAEHPYQEWLDKGLVPIDELPAGKYVRMPHHRLVMRQLAFGYTYEE MMAR_5413|M.marinum_M KAELAAEHPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEE MUL_5037|M.ulcerans_Agy99 KAELAAEHPYQEWLDNNLVPLEKLPSGEYARMAHERVVLRQLVFGYTYEE MAV_0166|M.avium_104 KAELAAEHPYQEWLDRNLVPLDDLPQGDYKRMPHDRLVKRQQTFGYTYEE TH_2102|M.thermoresistible__bu KAELAAEHPYQEWLDAGLFPLDELPQGDYQRMPHHRVVLRQRVFGYTSEE MAB_0091|M.abscessus_ATCC_1997 KAELAAAEPYQRWLEEGLVRLEQLPDRPHQHMPHNRIVLRQQVFGYTYEE Mflv_3593|M.gilvum_PYR-GCK KQELSAAQPYGEWLHSGLLELTTLPDRGHIQPNHESVVRRQVSFGYTEEE Mvan_2822|M.vanbaalenii_PYR-1 KEKLAHAEPYGEWLHSGLLELNALPDRARAQPNHESVVRRQISFGYTEED MSMEG_3225|M.smegmatis_MC2_155 KAQLSAAEPYEEWLHAGLLDLKTLPERGVAKPNHDSVVRRQIAFGYTEEE * .*: .** .**. .*. : ** : *. :* ** **** *: Mb3889c|M.bovis_AF2122/97 LNLLVAPMARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPP Rv3859c|M.tuberculosis_H37Rv LNLLVAPMARLGAEPIGSMGTDTPVAVLSQRPRMLYDYFHQLFAQVTNPP MLBr_00061|M.leprae_Br4923 LNLLVAPMVRAGSEPIGSMGADTPIAVLSRRPRMLYDYFHQLFAQVTNPP MMAR_5413|M.marinum_M LNLLVAPMVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPP MUL_5037|M.ulcerans_Agy99 LNLLVAPMVRTGAEPIGSMGTDTPIAVLSRRPRMLYDYFQQLFAQVTNPP MAV_0166|M.avium_104 LNLLVAPMVRTGAEPIGSMGTDTPVAVLSQRPRMLYDYFQQLFAQVTNPP TH_2102|M.thermoresistible__bu LNLIVGPMARTGAEPLGSMGTDTPIAVLSQRSRLLFDYFQQMFAQVTNPP MAB_0091|M.abscessus_ATCC_1997 INLLVAPMARTGAEALGSMGTDTPIAVLSNRSRMLFDYFQQLFAQVTNPP Mflv_3593|M.gilvum_PYR-GCK LRILLAPMAASGAEPLGSMGTDTPAAVLSQRSKLLYDYFVELFAQVTNPP Mvan_2822|M.vanbaalenii_PYR-1 LRILLTPMAASGVEPLGSMGTDTPPAVLSQRSKLLYDYFVELFAQVTNPP MSMEG_3225|M.smegmatis_MC2_155 LRVLLTPMAASGNEPLGSMGTDTPTAVLSSRSRLLYDYFVELFAQVTNPP :.::: **. * *.:****:*** **** *.::*:*** ::******** Mb3889c|M.bovis_AF2122/97 LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIVLPQPILRNHELAKLVS Rv3859c|M.tuberculosis_H37Rv LDAIREEVVTSLQGTTGGERDLLNPDQNSCHQIVLPQPILRNHELAKLVS MLBr_00061|M.leprae_Br4923 LDAIREEVVTSLQGTTGGEYDLLSPDENSCHQIWLPQPILRNYELAKLVN MMAR_5413|M.marinum_M LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLIN MUL_5037|M.ulcerans_Agy99 LDAIREEVVTSLQGTTGGERDLLNPDENSCHQIQLPQPILRNHELAKLIN MAV_0166|M.avium_104 LDAIREEVVTSLQGTTGGERDLLTPTELSCHQIVLSQPILRNRELAKLVN TH_2102|M.thermoresistible__bu LDAIREEVITSLQGVIGPEGDLLNPGPESCRQIVLPQPILRNHELAKLIN MAB_0091|M.abscessus_ATCC_1997 LDAIREEVVTSLGGVIGPEGDLLHPTAESCHQILLPQPVLHNDELDKLIH Mflv_3593|M.gilvum_PYR-GCK LDAIREEIVTSMARVMGPEQNLLEPGAASCRQIKLPWPVLDNDELGKIVH Mvan_2822|M.vanbaalenii_PYR-1 LDAIREEVVTSMARIMGPEQNLLEPSAASCRQIKLTWPVLDNDELNKIVH MSMEG_3225|M.smegmatis_MC2_155 LDAIREEVVTSMARVMGPEENLLEPTAASCRQIVLRAPVIDNDDLGKIVH *******::**: * * :** * **:** * *:: * :* *:: Mb3889c|M.bovis_AF2122/97 LDPNDKVNGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADG Rv3859c|M.tuberculosis_H37Rv LDPNDKVNGRPHGLRSKVIRCLYRVSEGGAGLAAALEEVRGAAAAAIADG MLBr_00061|M.leprae_Br4923 LDPADEVNGRPHGMRSTVVSCLYPVADAGAGLAAALTEVRAQASAAIVGG MMAR_5413|M.marinum_M LDPETVINGRPHGLKSKVVRCLYPVAEGGAGLAAALNEVRAQASAAIADG MUL_5037|M.ulcerans_Agy99 LDPETVINGRPHGLKSKVVRCLYPVAEGGSGLAAALNEVRAQASAAIADG MAV_0166|M.avium_104 LNPDDEVNGRPHGMRSKVIRCLYPVAEGGAGLAAALEDVRAQASAAIADG TH_2102|M.thermoresistible__bu VDPDHEVRGRKHGMRAAVVRCLFPVNRGGQGLKEALDRVRAKVSAAIREG MAB_0091|M.abscessus_ATCC_1997 LDPADTVNGRAHGFSSRVIRCLYPVAEGGAGLRTALESVRAEVSAAIAGG Mflv_3593|M.gilvum_PYR-GCK INDD----GEHPGLRTAVLRALYDVERGGEGLADALEDLRLRACEAIAKG Mvan_2822|M.vanbaalenii_PYR-1 INDD----GEQPGLRTTVLRALYNVERGGEGLAEAIEDLQLRASDAIAKG MSMEG_3225|M.smegmatis_MC2_155 INDD----GEHPGLRATVLRALYDVERGGEGLAEALDDLRRRASEAIADG :: *. *: : *: .*: * .* ** *: :: .. ** * Mb3889c|M.bovis_AF2122/97 ARIIILSDRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAR Rv3859c|M.tuberculosis_H37Rv ARIIILSDRESDEEMAPIPSLLAVAGVHHHLVRERTRTQVGLVVESGDAR MLBr_00061|M.leprae_Br4923 ARVIILSDRNSDEQMAPIPSLLSVAAVHHHLVRDRTRTHVGLVVESGDAR MMAR_5413|M.marinum_M ARIIVLSDRESDERMAPIPALLAVAGVHHHLVRERSRTKVGLVVESGDAR MUL_5037|M.ulcerans_Agy99 ARIIVLSDRESDERMAPIPALLAVAGVHHHLVRERTRTKVGLVVESGDAR MAV_0166|M.avium_104 ARVIILSDRESDEKMAPIPSLLAVAGVHHHLVRDRTRTHVGLVVESGDAR TH_2102|M.thermoresistible__bu ARIIVLSDRESDEQLAPIPSLLSVAAVHHHLVRDRTRTQVGLVVEAGDAR MAB_0091|M.abscessus_ATCC_1997 AQVIILSDRESDDLMAPIPSLLAVAAVHHHLVRERSRTKVGLVVEAGDAR Mflv_3593|M.gilvum_PYR-GCK ARTLVISDRDSDHTKAPVPSLLAVSAVHHHLVGTKQRTSVALVVESGDAR Mvan_2822|M.vanbaalenii_PYR-1 AHTLVISDRDSDHTKAPVPSLLAVSAVHHHLVRTKKRTTVALVVESGDAR MSMEG_3225|M.smegmatis_MC2_155 KRILVLSDRDSDHTRAPIPSLLAVSAVHHHLVRTKERTKVALVVESGDAR : :::***:**. **:*:**:*:.****** : ** *.****:**** Mb3889c|M.bovis_AF2122/97 EVHHMAALVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAA Rv3859c|M.tuberculosis_H37Rv EVHHMAALVGFGAAAINPYLVFESIEDMLDRGVIEGIDRTAALNNYIKAA MLBr_00061|M.leprae_Br4923 EVHHMAALIGFGAAAVNPYLVFESIEEMLDRGVIDGIDRKTALNNYIKAT MMAR_5413|M.marinum_M EVHHMAMLLGCGAAAVNPYLAFESIEDMLDRGVIDGIDRNTALSNYVKAA MUL_5037|M.ulcerans_Agy99 EVHHMAMLLGCGAAAVNPYLAFASIEDMLDRGVIDGIDRNTALSNYVKAA MAV_0166|M.avium_104 EVHHMAALVGFGAAAINPYMVFESIEDMLDRGVIEGIDRNTALNNYVKAA TH_2102|M.thermoresistible__bu EVHHMAALIGFGASAINPYLAFESIEDMLDRNLLEGLDRETALNNYIKAA MAB_0091|M.abscessus_ATCC_1997 EVHHVAALVGFGAAAVNPYMAFESIEDLIDRGVITGVDRDKAIRNYIKAA Mflv_3593|M.gilvum_PYR-GCK EVHHIAMLIGFGAAAVNPYLAFESIEDLIREGELTGIEPSTAVRNYLKAL Mvan_2822|M.vanbaalenii_PYR-1 EVHHIAMLIGFGAAAVNPYLAFESIEDLIREGELTGVDAATAVRNYLKAL MSMEG_3225|M.smegmatis_MC2_155 EVHHIALLIGFGAAAVNPYLAFESIEDLIREGELTGIEPAAAVRNYIKAL ****:* *:* **:*:***:.* ***::: .. : *:: *: **:** Mb3889c|M.bovis_AF2122/97 GKGVLKVMSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGIT Rv3859c|M.tuberculosis_H37Rv GKGVLKVMSKMGISTLASYTGAQLFQAVGISEQVLDEYFTGLTCPTGGIT MLBr_00061|M.leprae_Br4923 GQGVLKIMSKMGISTLASYVGAQLFQAVGISEDVLDEYFSGLSCPTGGIT MMAR_5413|M.marinum_M GKGVLKVMSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGIT MUL_5037|M.ulcerans_Agy99 GKGVLKVMSKMGISTLASYTGAQLFQAVGVSEEVLNEYFSGLTCATGGIT MAV_0166|M.avium_104 GKGVLKVMSKMGISTLASYTGAQLFQAVGISEDVLDEYFTGLSCPIGGIT TH_2102|M.thermoresistible__bu GKGVLKVMSKMGISTLRSYTGAQLFQAIGISQEVLDEYFTGLSCPTGGID MAB_0091|M.abscessus_ATCC_1997 GKGVLKVMSKMGISTLASYTGAQLFQAIGLSQELLDEYFTGLACPTGGIG Mflv_3593|M.gilvum_PYR-GCK GKGVMKVMSKMGISTVASYTAAQAFEAIGIDRDVIDEYFTGTPTQLGGIG Mvan_2822|M.vanbaalenii_PYR-1 GKGVMKVMSKMGISTVASYTAAQAFEAVGIDKAVIDEYFTGTPTQLGGIG MSMEG_3225|M.smegmatis_MC2_155 CKGVVKVMSKMGISTVASYTAAQVFEAIGLDRGVIDEYFTGTTSQLGGVG :**:*:********: **..** *:*:*:.. :::***:* . **: Mb3889c|M.bovis_AF2122/97 LDDIAADVAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV Rv3859c|M.tuberculosis_H37Rv LDDIAADVAARHRLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV MLBr_00061|M.leprae_Br4923 LDDIAAEVAVRHRVAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV MMAR_5413|M.marinum_M LDDIAADVATRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV MUL_5037|M.ulcerans_Agy99 LDDIAADVASRHTLAYLDRPDERAHRELEVGGEYQWRREGEYHLFNPETV MAV_0166|M.avium_104 LDDIAADVAARHALAYLDRPNERAHRELEVGGEYQWRREGEYHLFNPETV TH_2102|M.thermoresistible__bu LDDIAADVARRHELAYLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTV MAB_0091|M.abscessus_ATCC_1997 LDEIAADVASRHNLAFLDRPEEWAHRELEVGGEYQWRREGEYHLFNPDTV Mflv_3593|M.gilvum_PYR-GCK LDVIAEEVKLRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV Mvan_2822|M.vanbaalenii_PYR-1 LDVIAEEVKLRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV MSMEG_3225|M.smegmatis_MC2_155 LDVLADEVKMRHRRAYPENPTERVHRRLEVGGEYAFRREGELHLFTPEVV ** :* :* ** *: :.* * .**.******* :***** ***.*:.* Mb3889c|M.bovis_AF2122/97 FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDE Rv3859c|M.tuberculosis_H37Rv FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRTGVRPPVPLDE MLBr_00061|M.leprae_Br4923 FKLQHATRSGQYKIFKEYTRLVDDQSERMASLRGLLKFRSGVRTPVPLDE MMAR_5413|M.marinum_M FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDE MUL_5037|M.ulcerans_Agy99 FKLQHSTRTGQYKIFKEYTRLVDDQSERMASLRGLLKFRAGVRPPIPLDE MAV_0166|M.avium_104 FKLQHATRTGQYKIFKDYTRLVDDQSERMASLRGLLKFRAGVRPPVPLEE TH_2102|M.thermoresistible__bu FKLQHSTRTGQYEIFKEYTRLVDDQSERMASLRGLLKFKEGVRPPVPIEE MAB_0091|M.abscessus_ATCC_1997 FKLQHSTRTGQYSVFKEYTQLVDDQSERMASLRGLLKFKTGVRPPVPLDE Mflv_3593|M.gilvum_PYR-GCK FLLQHSTRTGRYEVFKQYSDEVDRLGRDGGALRGLFDFKKGLREPVPLDE Mvan_2822|M.vanbaalenii_PYR-1 FLLQHSTRTGRYEVFEQYSEEVNRLAREGGALRGLFEFKTGLRPPVPLHE MSMEG_3225|M.smegmatis_MC2_155 FLLQHSTRTGRRDIFAKYSEEVDRLSRKGGTLRGLFELKTGVRPPVPLEE * ***:**:*: .:* .*: *: .. .:****:.:: *:* *:*:.* Mb3889c|M.bovis_AF2122/97 VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVK Rv3859c|M.tuberculosis_H37Rv VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNCGEGGEDVK MLBr_00061|M.leprae_Br4923 VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVN MMAR_5413|M.marinum_M VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVG MUL_5037|M.ulcerans_Agy99 VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDVG MAV_0166|M.avium_104 VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGGRSNSGEGGEDVK TH_2102|M.thermoresistible__bu VEPASEIVKRFSTGAMSYGSISAEAHETLAIAMNRLGARSNSGEGGEHVS MAB_0091|M.abscessus_ATCC_1997 VEPASEIVKRFSTGAMSFGSISAEAHETLAIAMNRLGGRSNSGEGGEDPR Mflv_3593|M.gilvum_PYR-GCK VESADEIVKRFNTGAMSYGSISAEAHETMAIAMNALGGRSNSGEGGEDVD Mvan_2822|M.vanbaalenii_PYR-1 VESVDSIVTRFNTGAMSYGSISAEAHETMAVAMNNLGGRSNSGEGGEDVE MSMEG_3225|M.smegmatis_MC2_155 VEPVESIVTRFNTGAMSYGSISAEAHETMAIAMNKLGGRSNSGEGGEDVD **....**.**.*****:**********:*:*** **.***.*****. Mb3889c|M.bovis_AF2122/97 RFDRDPNGDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGG Rv3859c|M.tuberculosis_H37Rv RFDRDPNGDWRRSAIKQVASARFGVTSHYLTNCTDLQIKMAQGAKPGEGG MLBr_00061|M.leprae_Br4923 RFEPDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG MMAR_5413|M.marinum_M RFEQDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG MUL_5037|M.ulcerans_Agy99 RFEQDPNGDWRRSAIKQVASARFGVTSHYLTNCTDIQIKMAQGAKPGEGG MAV_0166|M.avium_104 RFDRDPDGSWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGG TH_2102|M.thermoresistible__bu RFDPDDNGDWRRSAIKQVASGRFGVTSHYLTNCTDIQIKMAQGAKPGEGG MAB_0091|M.abscessus_ATCC_1997 RFTPDENGDWRRSAIKQVASGRFGVTSHYLSNCTDIQIKMAQGAKPGEGG Mflv_3593|M.gilvum_PYR-GCK RLYDPK----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG Mvan_2822|M.vanbaalenii_PYR-1 RLYDPK----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG MSMEG_3225|M.smegmatis_MC2_155 RLYDPR----RRSAVKQVASGRFGVTSDYLVNATDIQIKMAQGAKPGEGG *: ****:*****.******.** *.**:************** Mb3889c|M.bovis_AF2122/97 QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP Rv3859c|M.tuberculosis_H37Rv QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP MLBr_00061|M.leprae_Br4923 QLPGRKVYPWIAQVRNSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP MMAR_5413|M.marinum_M QLPGHKVYPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP MUL_5037|M.ulcerans_Agy99 QLPGHKVYPWVAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP MAV_0166|M.avium_104 QLPGHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP TH_2102|M.thermoresistible__bu QLPGNKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANP MAB_0091|M.abscessus_ATCC_1997 QLPAHKVYPWVAEVRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNSNP Mflv_3593|M.gilvum_PYR-GCK QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANA Mvan_2822|M.vanbaalenii_PYR-1 QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANA MSMEG_3225|M.smegmatis_MC2_155 QLPGYKVYPNIAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANS ***. **** :*:.*:*******************************:*. Mb3889c|M.bovis_AF2122/97 SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG Rv3859c|M.tuberculosis_H37Rv SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG MLBr_00061|M.leprae_Br4923 SARVHVKLVSENGVGTVAAGVSKAHADVVLVSGHDGGTGATPLTSMKHSG MMAR_5413|M.marinum_M SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG MUL_5037|M.ulcerans_Agy99 SARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG MAV_0166|M.avium_104 AARVHVKLVSENGVGTVAAGVSKAHADVVLISGHDGGTGATPLTSMKHAG TH_2102|M.thermoresistible__bu QARVHVKLVSEAGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAG MAB_0091|M.abscessus_ATCC_1997 QARIHVKLVSENGVGTVATGVSKAHADVVLISGHDGGTGATPLTSMKHAG Mflv_3593|M.gilvum_PYR-GCK DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGYDGGTGAAPLTSLKHAG Mvan_2822|M.vanbaalenii_PYR-1 DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGYDGGTGAAPLTSLKHAG MSMEG_3225|M.smegmatis_MC2_155 DARIHVKLVSSVGVGTVAAGVSKAHADVVLISGHDGGTGAAPLTSLKHAG **:******. ******:***********:**:******:****:**:* Mb3889c|M.bovis_AF2122/97 APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGF Rv3859c|M.tuberculosis_H37Rv APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGAEEFGF MLBr_00061|M.leprae_Br4923 APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGF MMAR_5413|M.marinum_M APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGF MUL_5037|M.ulcerans_Agy99 APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIATLLGGEEFGF MAV_0166|M.avium_104 APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAALLGAEEFGF TH_2102|M.thermoresistible__bu APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVVIAALLGAEEFGF MAB_0091|M.abscessus_ATCC_1997 APWELGLAETQQTLLLNGLRDRIVVQVDGQLKTGRDVMIAMLLGGEEFGF Mflv_3593|M.gilvum_PYR-GCK APWEIGLADTQQTMVLNGLRDRITVQCDGGMRTARDVMVAMLLGAEEYGF Mvan_2822|M.vanbaalenii_PYR-1 APWEIGLADTQQTLMLNGLRDRITVQCDGGMRTARDVMVAMLLGAEEYGF MSMEG_3225|M.smegmatis_MC2_155 APWEIGLADTQQTLVLNGLRDRITVQCDGGLRTARDVVVAMLLGAEEYGF ****:***:****::********.** ** ::*.***::* ***.**:** Mb3889c|M.bovis_AF2122/97 ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFI Rv3859c|M.tuberculosis_H37Rv ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFTGKPEFVENFFMFI MLBr_00061|M.leprae_Br4923 ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRKRFNGKPEFVENFFMFI MMAR_5413|M.marinum_M ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFI MUL_5037|M.ulcerans_Agy99 ATAPLVVAGCIMMRVCHLDTCPVGVATQNPLLRERFNGKPEFVENFFMFI MAV_0166|M.avium_104 ATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRERFTGKPEFVENFFMFI TH_2102|M.thermoresistible__bu ATAPLVVSGCVMMRVCHLDTCPVGVATQNPVLRQRFTGKPEFVENFFLFI MAB_0091|M.abscessus_ATCC_1997 ATAPLVVSGCIMMRVCHLDTCPVGVATQNPVLRQRFNGKPEFVENFFLFI Mflv_3593|M.gilvum_PYR-GCK ATAPLVVSGCIMMRVCHLDTCPVGVATQNPQLRARFNGKPEFVENFFRFI Mvan_2822|M.vanbaalenii_PYR-1 ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENYFRFI MSMEG_3225|M.smegmatis_MC2_155 ATAPLVVSGCIMMRVCHLDTCPVGVATQNPELRARFNGKPEFVENFFTFI *******:**:******************* ** **.********:* ** Mb3889c|M.bovis_AF2122/97 AEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPE Rv3859c|M.tuberculosis_H37Rv AEEVREYLAQLGFRTVNEAVGQAGALDTTLARAHWKAHKLDLAPVLHEPE MLBr_00061|M.leprae_Br4923 AEEVREYMAQLGFRTFNEAVGQVGALDTTPVREHWKAHSIDLTPVLHEPE MMAR_5413|M.marinum_M AEEVREYMAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPE MUL_5037|M.ulcerans_Agy99 AEEVREYMAQLGFRTINEAVGQAGALDTTLARAHWKAHRLDLTPVLHEPE MAV_0166|M.avium_104 AEEVREYMAQLGFRTLNEAVGQVKSLDTTLARAHWKAHRLDLGPVLHEPE TH_2102|M.thermoresistible__bu AEEVREYMAKMGFRTVNEMVGQVGMLDTTRAAEHWKAHKLDLSPVLHQPE MAB_0091|M.abscessus_ATCC_1997 AEEVRELMAELGFRTVNEAVGQVGALDIERAVAHWKASKIDLTPVLTEPE Mflv_3593|M.gilvum_PYR-GCK AEDIRKYLAELGFRSIDEAVGHAEMLDTAAGVAHWKSRGLDLSPLFAVPD Mvan_2822|M.vanbaalenii_PYR-1 AEDIRKYLAELGFRSIDEAVGRAELLDTDMGVAHWKSKGLDLSPIFAVPS MSMEG_3225|M.smegmatis_MC2_155 AEDIRRYLAELGFRSIDEAVGHAELLDTAEGVAHWKTRGLDLDPIFAVPT **::*. :*::***:.:* **:. ** ***: :** *:: * Mb3889c|M.bovis_AF2122/97 SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN Rv3859c|M.tuberculosis_H37Rv SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTIGN MLBr_00061|M.leprae_Br4923 SAFMN--QDLYCSSRQDHGLDKVLDQQLIAVSRDALDFGKPVRFSTTIGN MMAR_5413|M.marinum_M SAFMN--QDLYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISN MUL_5037|M.ulcerans_Agy99 SAFMN--QGLYCSSSQDHGLDKALDQQLIVMSREALDSGKPVRFATTISN MAV_0166|M.avium_104 SAFMN--QDLYCSSRQDHGLDKALDQQLIVMSREALDSGKPVRFSTTISN TH_2102|M.thermoresistible__bu SAFMN--QDLYCSSRQDHGLDKALDQQLITMCREALDNGTPVRFSTTIAN MAB_0091|M.abscessus_ATCC_1997 SAFMN--QDLYCSGSQDHGLEKALDQQLIVMSREALDHGTPVKFETLITN Mflv_3593|M.gilvum_PYR-GCK TASQ-----RRRTRDQDHGLDQALDRTLIQLAEGALEDAHPVRLELPVRN Mvan_2822|M.vanbaalenii_PYR-1 NAHTGEPAARRRVRDQYHALDQALDQTLIQLAEGALEDAHPVRLELPIRN MSMEG_3225|M.smegmatis_MC2_155 DAHGAKLTQRRKLREQDHGLDQALDRTLIQLAEGALEDAHPVRLELPVRN * * *.*::.**: ** :.. **: . **:: : * Mb3889c|M.bovis_AF2122/97 VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR Rv3859c|M.tuberculosis_H37Rv VNRTVGTMLGHELTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPKGITLR MLBr_00061|M.leprae_Br4923 VNRTVGTMLGHELTKAYGAQGLPDGTIDITFEGSAGNSFGAFVPKGITLR MMAR_5413|M.marinum_M VNRTVGTMLGHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLR MUL_5037|M.ulcerans_Agy99 VNRTVGTMLGHEVTKAYGGQGLPDGSIDITFEGSAGNSFGAFVPKGITLR MAV_0166|M.avium_104 VNRTVGTMLGHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLR TH_2102|M.thermoresistible__bu VNRTVGTMLGHEVTKAYGGQGLPDGTIDITFDGSAGNSFGAFVPRGITLR MAB_0091|M.abscessus_ATCC_1997 VNRTVGTMLGHEVTKAYGGEGLPDDTIDITFTGSAGNSFGAFVPRGITLR Mflv_3593|M.gilvum_PYR-GCK VNRTVGTLLGSEVTRRYGAQGLPEDTIHIALTGSAGQSLGAFLPPGITLE Mvan_2822|M.vanbaalenii_PYR-1 VNRTVGTLLGSEVTRRYGAQGLPDDSIHVTLTGSAGQSIGAFLPPGITLE MSMEG_3225|M.smegmatis_MC2_155 VNRTVGTLLGSEVTRRYGAAGLPDDTIHVTLTGSAGQSIGAFLPPGITLE *******:** *:*: **. ***:.:*.::: ****:*:***:* ****. Mb3889c|M.bovis_AF2122/97 VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE Rv3859c|M.tuberculosis_H37Rv VYGDANDYVGKGLSGGRIVVRPSDDAPQDYVAEDNIIGGNVILFGATSGE MLBr_00061|M.leprae_Br4923 VYGDANDYVGKGLSGGRIVVRPSDSVPLNYVAEDNIIGGNVILFGATSGE MMAR_5413|M.marinum_M IYGDANDYVGKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGE MUL_5037|M.ulcerans_Agy99 IYGDANDYVGKGLSGGRIVVRPSDNAPPGYVAEDNIIGGNVILFGATSGE MAV_0166|M.avium_104 VYGDANDYVGKGLSGGRIVVRPSDNAPADYVAEDNIIGGNVILFGATSGE TH_2102|M.thermoresistible__bu VYGDANDYVGKGLSGGRIVVRPPDNVPESFVAEDNIIAGNVILFGATSGE MAB_0091|M.abscessus_ATCC_1997 LFGDANDYVGKGLSGGHIVVRPSREAPEGFVAEKNIIGGNVILFGATSGE Mflv_3593|M.gilvum_PYR-GCK LVGDANDYVGKGLSGGKIIVKPQDDV--LFLAEDNVIAGNTLLFGATSGE Mvan_2822|M.vanbaalenii_PYR-1 LVGDANDYVGKGLSGGKIIVKPQDDV--LFLPEDNVIAGNTLLYGATSGE MSMEG_3225|M.smegmatis_MC2_155 LVGDANDYVGKGLSGGRVVVRPPDDV--LFLPEDNVIAGNTLMYGATSGE : **************:::*:* .. ::.*.*:*.**.:::****** Mb3889c|M.bovis_AF2122/97 VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA Rv3859c|M.tuberculosis_H37Rv VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGRTGRNFAA MLBr_00061|M.leprae_Br4923 VYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVILGRTGRNFAA MMAR_5413|M.marinum_M VFLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGRVVILGQTGRNFAA MUL_5037|M.ulcerans_Agy99 VFLRGVVGERFAVRNSGAHVVVEGVGDHGCEYMTGGRVVILGQTGRNFAA MAV_0166|M.avium_104 AYLRGVVGERFAVRNSGAHAVVEGVGDHGCEYMTGGKVVVLGRTGRNFAA TH_2102|M.thermoresistible__bu VFLRGQVGERFAVRNSGALAVVEGVGDHGCEYMTGGRVVILGPVGRNFAA MAB_0091|M.abscessus_ATCC_1997 AFLNGVVGERFAVRNSGAAAVVEGVGDHGCEYMTGGTVVVLGPTGRNFAA Mflv_3593|M.gilvum_PYR-GCK LYLRGRVGERFAARNSGALTVVEGVGDHACEYMTGGRVVVLGKVGRNMAA Mvan_2822|M.vanbaalenii_PYR-1 LYLRGRVGERFAARNSGALAVVEGVGDHACEYMTGGRVVVLGKIGRNMAA MSMEG_3225|M.smegmatis_MC2_155 VYLRGRVGERFCARNSGALAVVEGVGDHACEYMTGGRVVILGKTGRNMAA :*.* *****..***** .********.******* **:** ***:** Mb3889c|M.bovis_AF2122/97 GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD Rv3859c|M.tuberculosis_H37Rv GMSGGVAYVYDPDGELPANLNSEMVELETLDEDDADWLHGTIQVHVDATD MLBr_00061|M.leprae_Br4923 GMSGGEAYVYDSDGELPANLNFEMVELEPLDFDDAAWLYATIQAHVDATD MMAR_5413|M.marinum_M GMSGGIAYVYDPDGELPDNLNTEMVDVETLDDDDSEFVHGIVQAHVDATD MUL_5037|M.ulcerans_Agy99 GMSGGIAYVYDPDGELPDNLNTEMVDVETLDDDDSEFVHGIVQAHVDATD MAV_0166|M.avium_104 GMSGGVAYIYDPPGEFPQHLNAEMVELESLDDDDIEWLHGMIQAHVDATD TH_2102|M.thermoresistible__bu GMSGGIAYVYDPDGVLPGRLNREMVELESLDDEDREWLRGFIAAHVDATD MAB_0091|M.abscessus_ATCC_1997 GMSGGVAYVYDPDKRLMDNLNDEMVDLDALDPDDQQVLRSLIEKHVAATD Mflv_3593|M.gilvum_PYR-GCK GMSGGIAFVLGLD---PRRVNTAMVELQRLEPEDLAWLHGVVGQHARYTG Mvan_2822|M.vanbaalenii_PYR-1 GMSGGIAFVLGLD---PSRVNTDMVELQALEPEDLAWLRDVVAQHAHYTG MSMEG_3225|M.smegmatis_MC2_155 GMSGGIAFVLGLD---PARVNTEMVQLQRLDPEDLEWLHHVVTDHVRYTG ***** *:: . .:* **::: *: :* : : *. *. Mb3889c|M.bovis_AF2122/97 SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA Rv3859c|M.tuberculosis_H37Rv SAVGQRILSDWSGQQRHFVKVMPRDYKRVLQAIALAERDGVDVDKAIMAA MLBr_00061|M.leprae_Br4923 SAVGQRILAGWSEQQRYFVKVMPKDYKRVLQAIALAERNGVDVNKVIMEP MMAR_5413|M.marinum_M SAVGQRVLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVDIDKAIMAA MUL_5037|M.ulcerans_Agy99 SAVGQRVLADWPQQQRHFVKVMPRDYKRVLQAIAEAERDGVDIDKAIMAA MAV_0166|M.avium_104 SAVGQRILGDWAQQQRHFVKVMPRDYKRVLQAIAEAERDGGDVDKAIMAA TH_2102|M.thermoresistible__bu SAIGQRILNDWDEHVTHFAKVMPRDYKRVLTAIAEAEASGADVDEAIMAA MAB_0091|M.abscessus_ATCC_1997 SAVGQRILADWSGHSDSFVKVMPRDYRRVLEAIADAELTGGDVNEAIMAA Mflv_3593|M.gilvum_PYR-GCK STVATSLLSDWPRRSAQFTKIMPRDYQRVLQATRMAKAEGRDVDSAIMEA Mvan_2822|M.vanbaalenii_PYR-1 STVATSVLSDWPRRSAQFTKVMPRDFQRVLQATRMAKAEGRDVDTAIMEA MSMEG_3225|M.smegmatis_MC2_155 STLGTSLLSDWPRRSAQFTKIMPTDYQRVLQATRMAKAEGRDVDSAIMEA *::. :* .* : *.*:** *::*** * *: * *:: .** . Mb3889c|M.bovis_AF2122/97 AHG Rv3859c|M.tuberculosis_H37Rv AHG MLBr_00061|M.leprae_Br4923 AHG MMAR_5413|M.marinum_M SHG MUL_5037|M.ulcerans_Agy99 SHG MAV_0166|M.avium_104 AHG TH_2102|M.thermoresistible__bu ANG MAB_0091|M.abscessus_ATCC_1997 ARG Mflv_3593|M.gilvum_PYR-GCK SRG Mvan_2822|M.vanbaalenii_PYR-1 SRG MSMEG_3225|M.smegmatis_MC2_155 SRG :.*