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VSVVTTDAQAAHAAGVSRLLASYRAIPPSATVRLAKPTSNLFRARARTNVKGLDVSGLTGVIGVDPDART ADVAGMCTYEDLVAATLPYGLAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDILTGSGEIV TASPDQHSDLFHAFPNSYGTLGYSTRLRIELEPVHPFVALRHLRFHSITDLVAAMDRIIETGGLDGEPVD YLDGVVFSATESYLCVGFKTKTPGPVSDYTGQQIFYRSIQHDGDTGAEKHDRLTIHDYLWRWDTDWFWCS RAFGAQHPVIRRFWPRRLRRSSFYWKLVAYDQRYDIADRIEKRNGRPPRERVVQDVEVPIERCADFVEWF LQNVPIEPIWLCPLRLRDSADGGASWPLYPLKAHHTYVNIGFWSSVPVGPEEGHTNRLIEKKVAELDGHK SLYSDAYYTRDEFDELYGGEVYNTVKKTYDPDSRLLDLYSKAVQRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6283 | - | - | 100% (466) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1964 | - | 3e-13 | 33.61% (122) | mitomycin radical oxidase |
| M. smegmatis MC2 155 | MSMEG_6382 | - | 5e-09 | 32.80% (125) | oxidoreductase, FAD-binding |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3746 | - | 0.0 | 76.03% (463) | hypothetical protein Mb3746 |
| M. gilvum PYR-GCK | Mflv_1284 | - | 0.0 | 79.66% (467) | FAD linked oxidase domain-containing protein |
| M. tuberculosis H37Rv | Rv3719 | - | 0.0 | 76.03% (463) | hypothetical protein Rv3719 |
| M. leprae Br4923 | MLBr_02333 | - | 0.0 | 74.30% (463) | hypothetical protein MLBr_02333 |
| M. abscessus ATCC 19977 | MAB_0311c | - | 0.0 | 74.67% (458) | hypothetical protein MAB_0311c |
| M. marinum M | MMAR_5235 | - | 0.0 | 77.92% (462) | dehydrogenase |
| M. avium 104 | MAV_0384 | - | 0.0 | 76.34% (465) | FAD/FMN-containing dehydrogenase |
| M. thermoresistible (build 8) | TH_2291 | - | 0.0 | 80.56% (463) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4310 | - | 0.0 | 78.12% (448) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5531 | - | 0.0 | 80.94% (467) | FAD linked oxidase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6283|M.smegmatis_MC2_155 -----------MSVVTTDAQAAHAAGVSRLLASYRAIPPSATVRLAKPTS
TH_2291|M.thermoresistible__bu --------------VTTDARAAHAAGVRRLLESYRAIPPDATVRLAKPTS
Mflv_1284|M.gilvum_PYR-GCK -----------MSVAVTDARAAHAHGVQRLLASYRAIPADATVRLAKPTS
Mvan_5531|M.vanbaalenii_PYR-1 -----------MSVPSTDARSAHADGVQRLLASYRAIPQDATVRLAKPTS
MLBr_02333|M.leprae_Br4923 -----------MVSVQESALVVYTSGVKRLVASYRSIPATSPVRLAKPTS
MAV_0384|M.avium_104 MHGLLSKTRVYLVPVLGSALSAHQAGVDRLLESYRSIPATSAVRLAKPSS
Mb3746|M.bovis_AF2122/97 MQGQLSRTRVYAVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
Rv3719|M.tuberculosis_H37Rv MQGQLSRTRVYTVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
MMAR_5235|M.marinum_M MQGLWSVTTIYVVPGTGSGLSAHTSGVERLLASYRSIPTTATVRLAKPTS
MUL_4310|M.ulcerans_Agy99 -----------------------------MLASYRSIPTTATVRLAKPTS
MAB_0311c|M.abscessus_ATCC_199 --------------MPIASGSAHAEGVNRLLRSYRAIPTTATVRLAKPTS
:: ***:** :.:*****:*
MSMEG_6283|M.smegmatis_MC2_155 NLFRARARTNVKGLDVSGLTGVIGVDPDARTADVAGMCTYEDLVAATLPY
TH_2291|M.thermoresistible__bu NLFRARAKNTVRGLDVSGLTDVIAVDPQTRTAEVAGMCTYEDLVAATLPY
Mflv_1284|M.gilvum_PYR-GCK NLFRARVENTGRGLDTSGLTHVIAVDPDARTADVAGMCTYEDLVAATLPY
Mvan_5531|M.vanbaalenii_PYR-1 NLFRARAKTRTKGLDTSGLTNVIAVDAEARTADVAGMCTYEDLVAATLPH
MLBr_02333|M.leprae_Br4923 NLFRTRAKRDAPGLDASGLTGVIGIDTEARTADVAGMCTYEDLVAATLPY
MAV_0384|M.avium_104 NLFRARTKRDAPGLDTSGLTGVLGVDPETRTADVAGMCTYEDLVAATLPY
Mb3746|M.bovis_AF2122/97 NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
Rv3719|M.tuberculosis_H37Rv NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
MMAR_5235|M.marinum_M NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MUL_4310|M.ulcerans_Agy99 NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MAB_0311c|M.abscessus_ATCC_199 NLFRARAKPTTPGLDTSGLTGVIDVDPVNRTAEVAGMCTYEDLVAATLAH
****:*.. ***.**** *: :*. ***:**********:**** :
MSMEG_6283|M.smegmatis_MC2_155 GLAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDILTGSGEI
TH_2291|M.thermoresistible__bu ALAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDVLTGAGEV
Mflv_1284|M.gilvum_PYR-GCK GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGTGDI
Mvan_5531|M.vanbaalenii_PYR-1 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGTGDV
MLBr_02333|M.leprae_Br4923 GLLPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MAV_0384|M.avium_104 GLSPLVVPQLKTITLGGAVSGLGIESASFRNGLPHESVLEMDILTGAGEL
Mb3746|M.bovis_AF2122/97 GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
Rv3719|M.tuberculosis_H37Rv GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MMAR_5235|M.marinum_M GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MUL_4310|M.ulcerans_Agy99 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGAGEL
MAB_0311c|M.abscessus_ATCC_199 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGSGEI
.* *******:********:******:***************:***:*::
MSMEG_6283|M.smegmatis_MC2_155 VTASPDQHSDLFHAFPNSYGTLGYSTRLRIELEPVHPFVALRHLRFHSIT
TH_2291|M.thermoresistible__bu LTTSPTRHPDLFRAFPNSYGTLGYAVRLKIELEPVRPFVAIRHLRFGSVP
Mflv_1284|M.gilvum_PYR-GCK VRASADENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLP
Mvan_5531|M.vanbaalenii_PYR-1 VRASPDENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLS
MLBr_02333|M.leprae_Br4923 LTVSANQHGDLYRAFPNSYGTLGYSTRFRISLEPVTPFVALRHIRFHLLT
MAV_0384|M.avium_104 LTASRTQHADLFRAFPNSYGTLGYSTRLRIELEPVAPFVTLRHIRFHALA
Mb3746|M.bovis_AF2122/97 LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
Rv3719|M.tuberculosis_H37Rv LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
MMAR_5235|M.marinum_M LTVSADRHADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MUL_4310|M.ulcerans_Agy99 LTVSADRNADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MAB_0311c|M.abscessus_ATCC_199 VTAAPDRLADLYRGFPNSYGTLGYSVRLRIQLEPVKPFVALRHIRFHSLE
: .: . **::.**********:.*::* **** ***:::*:** :
MSMEG_6283|M.smegmatis_MC2_155 DLVAAMDRIIETGGLDGEPVDYLDGVVFSATESYLCVGFKTKTPGPVSDY
TH_2291|M.thermoresistible__bu DLVAEMDRIIAAGEYDGIPVDYLDGVVFSAQESYLTLGFKTTTPGPVSDY
Mflv_1284|M.gilvum_PYR-GCK NLIAAMDRIVETGGWNGDQVDYLDGVVFSADESYLCVGIQSATPGPVSDY
Mvan_5531|M.vanbaalenii_PYR-1 ALIEAMDRIVETGGLNGEPVDYLDGVVFSAEESYLCVGQRSATPGPVSDY
MLBr_02333|M.leprae_Br4923 EMVTAMENIIDTGGHDGVPVDYLDGVVFSANESYLCIGKRTTTPGPVSDY
MAV_0384|M.avium_104 DLIAAAERIIDTGGHAGTPVDYLDGVVFSADESYLCVGRRTTTPGPVSDY
Mb3746|M.bovis_AF2122/97 AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
Rv3719|M.tuberculosis_H37Rv AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
MMAR_5235|M.marinum_M ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MUL_4310|M.ulcerans_Agy99 ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MAB_0311c|M.abscessus_ATCC_199 ELVSVMESIVNTAAYEGESVDYLDGVVFAADECYLSLGALTAAPGPVSDY
:: : *: :. * *********:* *.** :* : .*******
MSMEG_6283|M.smegmatis_MC2_155 TGQQIFYRSIQHDGDT-GAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
TH_2291|M.thermoresistible__bu TGQQIYYRSIQHAEG----VKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
Mflv_1284|M.gilvum_PYR-GCK TGDDIFYRSIQHDSPTDGGEKHDRLTVHDYFWRWDTDWFWCSRAFGAQNP
Mvan_5531|M.vanbaalenii_PYR-1 TGKQIYYRSIQHDGPTDGAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQNP
MLBr_02333|M.leprae_Br4923 TGQHIYYRSIQHDN----EVKEDRLTIHDYVWRWDTDWFWCSRAFGAQNQ
MAV_0384|M.avium_104 TGQHIYYQSIRHDSPGDEPTKDDRLTMHDYFWRWDTDWFWCSRAFGVQNP
Mb3746|M.bovis_AF2122/97 TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
Rv3719|M.tuberculosis_H37Rv TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
MMAR_5235|M.marinum_M TGKDIYYRSIQHESG----IKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MUL_4310|M.ulcerans_Agy99 TGKDIYYRSIQHESG----VKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MAB_0311c|M.abscessus_ATCC_199 TGQRVYYRSIQHPDG----ISNDRLTIHDYLWRWDTDWFWCSRAFGAQNP
**. ::*:**:* . **** ***.************:**.*:
MSMEG_6283|M.smegmatis_MC2_155 VIRRFWPRRLRRSSFYWKLVAYDQRYDIADRIEKRNGRPPRERVVQDVEV
TH_2291|M.thermoresistible__bu TIRRLWPRRLRRSSFYWKLISYDQRFGIADRIERWNGRPPRERVVQDIEV
Mflv_1284|M.gilvum_PYR-GCK KIRRWWPRRYRRSSFYWKLIGYDQRFGIADRIEKRAGRPLRERVVQDVEV
Mvan_5531|M.vanbaalenii_PYR-1 RIRRWWPRRYRRSSVYWKLIGYDRRFGIADRIEKRNGRPPRERVVQDIEV
MLBr_02333|M.leprae_Br4923 QLRRWWPRRYRRSSVYWKLMAADRRFGIVDRIEARNGRPLRERVVQDVEL
MAV_0384|M.avium_104 RVRRWWPRRYRRSSVYSKLVSLDRRLRISDRIEARNGRPPRERVVQDVEL
Mb3746|M.bovis_AF2122/97 RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
Rv3719|M.tuberculosis_H37Rv RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
MMAR_5235|M.marinum_M TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MUL_4310|M.ulcerans_Agy99 TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MAB_0311c|M.abscessus_ATCC_199 GIRRLWPRKYRRSSVYWKLIALDQRYDIADRIERFNGRPARERVVQDVEV
:** ***: **** * :*: *:* * **:* *** *******:*:
MSMEG_6283|M.smegmatis_MC2_155 PIERCADFVEWFLQNVPIEPIWLCPLRLRDSADGGASWPLYPLKAHHTYV
TH_2291|M.thermoresistible__bu PLERCAEFIDWFLEYIPIEPIWLCPLRLR-STDPDGVWPLYPLRPGRTYV
Mflv_1284|M.gilvum_PYR-GCK PIERTVEFLQWFLGTIPIEPIWLCPLRLR----DDNSWSLYPLRPHRTYV
Mvan_5531|M.vanbaalenii_PYR-1 PIERTVEFLQWFLDTVPIEPIWLCPLRLR----DDRDWPLYPIRPHHTYV
MLBr_02333|M.leprae_Br4923 PIERTCEFLEWFLGSVPIAPIWLCPLRLR----DHNSWPLYPIQPDHSYV
MAV_0384|M.avium_104 PVERTLEFLEWFLETVPITPIWLCPLRLR----DHDGWPLYPMRPDHTYV
Mb3746|M.bovis_AF2122/97 PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
Rv3719|M.tuberculosis_H37Rv PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
MMAR_5235|M.marinum_M PIERTQDFVTWFLETVPIAPIWLCPLRLR----DNDGWPLYPIRPDHSYV
MUL_4310|M.ulcerans_Agy99 PIERTQDFMTWFLETVPIAPIWLCPLRLR----DSDGWPLYPIRPDHSYV
MAB_0311c|M.abscessus_ATCC_199 PISRTPEFLRWFLDEIPIEPVWVCPLRLR----DSEGWPLYPIRPGQTYV
*:.* :*: ** :** *:*:****** *.***::. ::**
MSMEG_6283|M.smegmatis_MC2_155 NIGFWSSVPVGPEEGHTNRLIEKKVAELDGHKSLYSDAYYTRDEFDELYG
TH_2291|M.thermoresistible__bu NIGFWSSVPAGDTEGATNRLIERKVSELDGHKSLYSDAFYSPDEFDELYG
Mflv_1284|M.gilvum_PYR-GCK NVGFWSSVPVGPEEGHTNKLIERRISELEGHKSLYSDAFYSADEFDALYG
Mvan_5531|M.vanbaalenii_PYR-1 NVGFWSSVPVGPEEGYTNRMIERKVSDLDGHKSLYSDAYYSPEEFDSLYG
MLBr_02333|M.leprae_Br4923 NVGFWSSVPAGATEGETNRTIEAKVSALDGHKSLYSDSFYTREEFNELYG
MAV_0384|M.avium_104 NVGFWSSVPAGATEGATNRLIEAKVSELDGHKSLYSDSFYTREEFDELYG
Mb3746|M.bovis_AF2122/97 NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
Rv3719|M.tuberculosis_H37Rv NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
MMAR_5235|M.marinum_M NIGFWSSVPAGATEGATNREIETKVSELNGHKSLYSDSYYTREEFDELYG
MUL_4310|M.ulcerans_Agy99 NIGFWSSVPAGATEGATNREIETKVSEVNGHKPLYSDSYYTREEFDELYG
MAB_0311c|M.abscessus_ATCC_199 NIGFWSSVPAGAVEGATNRLIERKVSELGGHKSLYSESFYTRDEFEPLYG
*:*******.* ** **: ** ::: : ***.***:::*: :**: ***
MSMEG_6283|M.smegmatis_MC2_155 GEVYNTVKKTYDPDSRLLDLYSKAVQRQ
TH_2291|M.thermoresistible__bu GETYKTVKKTYDPDGRLLDLYAKAVLRR
Mflv_1284|M.gilvum_PYR-GCK GEIYRTVKKTYDPDSRFLDLYAKAVRRQ
Mvan_5531|M.vanbaalenii_PYR-1 GETYKTVKKTYDPDSRFLDLYGKAVGRQ
MLBr_02333|M.leprae_Br4923 GESYNAVKKIYDPDSRLLDLYAKVVQRR
MAV_0384|M.avium_104 GEAYNTVKKTYDPDSRLLDLYAKAVQRR
Mb3746|M.bovis_AF2122/97 GETYNTVKKAYDPDSRLLDLYAKAVQRR
Rv3719|M.tuberculosis_H37Rv GETYNTVKKAYDPDSRLLDLYAKAVQRR
MMAR_5235|M.marinum_M GESYKTVKKTYDPDSRLLDLYAKAVQRR
MUL_4310|M.ulcerans_Agy99 GESYKTVKKTYDPDSRLLDLYAKAVQRR
MAB_0311c|M.abscessus_ATCC_199 GEHYQTLKKTYDPDNRLLDLYAKAVRRQ
** *.::** ****.*:****.*.* *: