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M. thermoresistible (build 8) TH_2291 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 4495593 - 4496972
length: 460

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2291-100% (460)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1603-6e-0826.37% (201) PROBABLE OXIDOREDUCTASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3746-0.074.73% (459) hypothetical protein Mb3746
M. gilvum PYR-GCKMflv_1284-0.077.66% (461) FAD linked oxidase domain-containing protein
M. tuberculosis H37RvRv3719-0.074.73% (459) hypothetical protein Rv3719
M. leprae Br4923MLBr_02333-0.071.46% (459) hypothetical protein MLBr_02333
M. abscessus ATCC 19977MAB_0311c-0.075.50% (453) hypothetical protein MAB_0311c
M. marinum MMMAR_5235-0.076.64% (458) dehydrogenase
M. avium 104MAV_0384-0.074.73% (463) FAD/FMN-containing dehydrogenase
M. smegmatis MC2 155MSMEG_6283-0.080.56% (463) FAD binding domain-containing protein
M. ulcerans Agy99MUL_4310-0.077.48% (444) dehydrogenase
M. vanbaalenii PYR-1Mvan_5531-0.078.14% (462) FAD linked oxidase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2291|M.thermoresistible__bu      --------------VTTDARAAHAAGVRRLLESYRAIPPDATVRLAKPTS
MSMEG_6283|M.smegmatis_MC2_155      -----------MSVVTTDAQAAHAAGVSRLLASYRAIPPSATVRLAKPTS
Mflv_1284|M.gilvum_PYR-GCK          -----------MSVAVTDARAAHAHGVQRLLASYRAIPADATVRLAKPTS
Mvan_5531|M.vanbaalenii_PYR-1       -----------MSVPSTDARSAHADGVQRLLASYRAIPQDATVRLAKPTS
MLBr_02333|M.leprae_Br4923          -----------MVSVQESALVVYTSGVKRLVASYRSIPATSPVRLAKPTS
MAV_0384|M.avium_104                MHGLLSKTRVYLVPVLGSALSAHQAGVDRLLESYRSIPATSAVRLAKPSS
Mb3746|M.bovis_AF2122/97            MQGQLSRTRVYAVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
Rv3719|M.tuberculosis_H37Rv         MQGQLSRTRVYTVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
MMAR_5235|M.marinum_M               MQGLWSVTTIYVVPGTGSGLSAHTSGVERLLASYRSIPTTATVRLAKPTS
MUL_4310|M.ulcerans_Agy99           -----------------------------MLASYRSIPTTATVRLAKPTS
MAB_0311c|M.abscessus_ATCC_199      --------------MPIASGSAHAEGVNRLLRSYRAIPTTATVRLAKPTS
                                                                 :: ***:**  :.:*****:*

TH_2291|M.thermoresistible__bu      NLFRARAKNTVRGLDVSGLTDVIAVDPQTRTAEVAGMCTYEDLVAATLPY
MSMEG_6283|M.smegmatis_MC2_155      NLFRARARTNVKGLDVSGLTGVIGVDPDARTADVAGMCTYEDLVAATLPY
Mflv_1284|M.gilvum_PYR-GCK          NLFRARVENTGRGLDTSGLTHVIAVDPDARTADVAGMCTYEDLVAATLPY
Mvan_5531|M.vanbaalenii_PYR-1       NLFRARAKTRTKGLDTSGLTNVIAVDAEARTADVAGMCTYEDLVAATLPH
MLBr_02333|M.leprae_Br4923          NLFRTRAKRDAPGLDASGLTGVIGIDTEARTADVAGMCTYEDLVAATLPY
MAV_0384|M.avium_104                NLFRARTKRDAPGLDTSGLTGVLGVDPETRTADVAGMCTYEDLVAATLPY
Mb3746|M.bovis_AF2122/97            NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
Rv3719|M.tuberculosis_H37Rv         NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
MMAR_5235|M.marinum_M               NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MUL_4310|M.ulcerans_Agy99           NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MAB_0311c|M.abscessus_ATCC_199      NLFRARAKPTTPGLDTSGLTGVIDVDPVNRTAEVAGMCTYEDLVAATLAH
                                    ****:*..    ***.**** *: :*.  ***:**********:**** :

TH_2291|M.thermoresistible__bu      ALAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDVLTGAGEV
MSMEG_6283|M.smegmatis_MC2_155      GLAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDILTGSGEI
Mflv_1284|M.gilvum_PYR-GCK          GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGTGDI
Mvan_5531|M.vanbaalenii_PYR-1       GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGTGDV
MLBr_02333|M.leprae_Br4923          GLLPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MAV_0384|M.avium_104                GLSPLVVPQLKTITLGGAVSGLGIESASFRNGLPHESVLEMDILTGAGEL
Mb3746|M.bovis_AF2122/97            GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
Rv3719|M.tuberculosis_H37Rv         GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MMAR_5235|M.marinum_M               GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MUL_4310|M.ulcerans_Agy99           GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGAGEL
MAB_0311c|M.abscessus_ATCC_199      GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGSGEI
                                    .* *******:********:******:***************:***:*::

TH_2291|M.thermoresistible__bu      LTTSPTRHPDLFRAFPNSYGTLGYAVRLKIELEPVRPFVAIRHLRFGSVP
MSMEG_6283|M.smegmatis_MC2_155      VTASPDQHSDLFHAFPNSYGTLGYSTRLRIELEPVHPFVALRHLRFHSIT
Mflv_1284|M.gilvum_PYR-GCK          VRASADENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLP
Mvan_5531|M.vanbaalenii_PYR-1       VRASPDENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLS
MLBr_02333|M.leprae_Br4923          LTVSANQHGDLYRAFPNSYGTLGYSTRFRISLEPVTPFVALRHIRFHLLT
MAV_0384|M.avium_104                LTASRTQHADLFRAFPNSYGTLGYSTRLRIELEPVAPFVTLRHIRFHALA
Mb3746|M.bovis_AF2122/97            LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
Rv3719|M.tuberculosis_H37Rv         LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
MMAR_5235|M.marinum_M               LTVSADRHADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MUL_4310|M.ulcerans_Agy99           LTVSADRNADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MAB_0311c|M.abscessus_ATCC_199      VTAAPDRLADLYRGFPNSYGTLGYSVRLRIQLEPVKPFVALRHIRFHSLE
                                    : .:  .  **::.**********:.*::* **** ***:::*:**  : 

TH_2291|M.thermoresistible__bu      DLVAEMDRIIAAGEYDGIPVDYLDGVVFSAQESYLTLGFKTTTPGPVSDY
MSMEG_6283|M.smegmatis_MC2_155      DLVAAMDRIIETGGLDGEPVDYLDGVVFSATESYLCVGFKTKTPGPVSDY
Mflv_1284|M.gilvum_PYR-GCK          NLIAAMDRIVETGGWNGDQVDYLDGVVFSADESYLCVGIQSATPGPVSDY
Mvan_5531|M.vanbaalenii_PYR-1       ALIEAMDRIVETGGLNGEPVDYLDGVVFSAEESYLCVGQRSATPGPVSDY
MLBr_02333|M.leprae_Br4923          EMVTAMENIIDTGGHDGVPVDYLDGVVFSANESYLCIGKRTTTPGPVSDY
MAV_0384|M.avium_104                DLIAAAERIIDTGGHAGTPVDYLDGVVFSADESYLCVGRRTTTPGPVSDY
Mb3746|M.bovis_AF2122/97            AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
Rv3719|M.tuberculosis_H37Rv         AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
MMAR_5235|M.marinum_M               ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MUL_4310|M.ulcerans_Agy99           ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MAB_0311c|M.abscessus_ATCC_199      ELVSVMESIVNTAAYEGESVDYLDGVVFAADECYLSLGALTAAPGPVSDY
                                     ::   : *: :.   *  *********:* *.** :*  : .*******

TH_2291|M.thermoresistible__bu      TGQQIYYRSIQHAEG----VKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
MSMEG_6283|M.smegmatis_MC2_155      TGQQIFYRSIQHDGDT-GAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
Mflv_1284|M.gilvum_PYR-GCK          TGDDIFYRSIQHDSPTDGGEKHDRLTVHDYFWRWDTDWFWCSRAFGAQNP
Mvan_5531|M.vanbaalenii_PYR-1       TGKQIYYRSIQHDGPTDGAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQNP
MLBr_02333|M.leprae_Br4923          TGQHIYYRSIQHDN----EVKEDRLTIHDYVWRWDTDWFWCSRAFGAQNQ
MAV_0384|M.avium_104                TGQHIYYQSIRHDSPGDEPTKDDRLTMHDYFWRWDTDWFWCSRAFGVQNP
Mb3746|M.bovis_AF2122/97            TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
Rv3719|M.tuberculosis_H37Rv         TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
MMAR_5235|M.marinum_M               TGKDIYYRSIQHESG----IKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MUL_4310|M.ulcerans_Agy99           TGKDIYYRSIQHESG----VKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MAB_0311c|M.abscessus_ATCC_199      TGQRVYYRSIQHPDG----ISNDRLTIHDYLWRWDTDWFWCSRAFGAQNP
                                    **. ::*:**:*        . **** ***.************:**.*: 

TH_2291|M.thermoresistible__bu      TIRRLWPRRLRRSSFYWKLISYDQRFGIADRIERWNGRPPRERVVQDIEV
MSMEG_6283|M.smegmatis_MC2_155      VIRRFWPRRLRRSSFYWKLVAYDQRYDIADRIEKRNGRPPRERVVQDVEV
Mflv_1284|M.gilvum_PYR-GCK          KIRRWWPRRYRRSSFYWKLIGYDQRFGIADRIEKRAGRPLRERVVQDVEV
Mvan_5531|M.vanbaalenii_PYR-1       RIRRWWPRRYRRSSVYWKLIGYDRRFGIADRIEKRNGRPPRERVVQDIEV
MLBr_02333|M.leprae_Br4923          QLRRWWPRRYRRSSVYWKLMAADRRFGIVDRIEARNGRPLRERVVQDVEL
MAV_0384|M.avium_104                RVRRWWPRRYRRSSVYSKLVSLDRRLRISDRIEARNGRPPRERVVQDVEL
Mb3746|M.bovis_AF2122/97            RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
Rv3719|M.tuberculosis_H37Rv         RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
MMAR_5235|M.marinum_M               TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MUL_4310|M.ulcerans_Agy99           TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MAB_0311c|M.abscessus_ATCC_199      GIRRLWPRKYRRSSVYWKLIALDQRYDIADRIERFNGRPARERVVQDVEV
                                     :** ***: **** * :*:  *:*  * **:*   *** *******:*:

TH_2291|M.thermoresistible__bu      PLERCAEFIDWFLEYIPIEPIWLCPLRLR-STDPDGVWPLYPLRPGRTYV
MSMEG_6283|M.smegmatis_MC2_155      PIERCADFVEWFLQNVPIEPIWLCPLRLRDSADGGASWPLYPLKAHHTYV
Mflv_1284|M.gilvum_PYR-GCK          PIERTVEFLQWFLGTIPIEPIWLCPLRLR----DDNSWSLYPLRPHRTYV
Mvan_5531|M.vanbaalenii_PYR-1       PIERTVEFLQWFLDTVPIEPIWLCPLRLR----DDRDWPLYPIRPHHTYV
MLBr_02333|M.leprae_Br4923          PIERTCEFLEWFLGSVPIAPIWLCPLRLR----DHNSWPLYPIQPDHSYV
MAV_0384|M.avium_104                PVERTLEFLEWFLETVPITPIWLCPLRLR----DHDGWPLYPMRPDHTYV
Mb3746|M.bovis_AF2122/97            PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
Rv3719|M.tuberculosis_H37Rv         PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
MMAR_5235|M.marinum_M               PIERTQDFVTWFLETVPIAPIWLCPLRLR----DNDGWPLYPIRPDHSYV
MUL_4310|M.ulcerans_Agy99           PIERTQDFMTWFLETVPIAPIWLCPLRLR----DSDGWPLYPIRPDHSYV
MAB_0311c|M.abscessus_ATCC_199      PISRTPEFLRWFLDEIPIEPVWVCPLRLR----DSEGWPLYPIRPGQTYV
                                    *:.*  :*: **   :** *:*:******        *.***::. ::**

TH_2291|M.thermoresistible__bu      NIGFWSSVPAGDTEGATNRLIERKVSELDGHKSLYSDAFYSPDEFDELYG
MSMEG_6283|M.smegmatis_MC2_155      NIGFWSSVPVGPEEGHTNRLIEKKVAELDGHKSLYSDAYYTRDEFDELYG
Mflv_1284|M.gilvum_PYR-GCK          NVGFWSSVPVGPEEGHTNKLIERRISELEGHKSLYSDAFYSADEFDALYG
Mvan_5531|M.vanbaalenii_PYR-1       NVGFWSSVPVGPEEGYTNRMIERKVSDLDGHKSLYSDAYYSPEEFDSLYG
MLBr_02333|M.leprae_Br4923          NVGFWSSVPAGATEGETNRTIEAKVSALDGHKSLYSDSFYTREEFNELYG
MAV_0384|M.avium_104                NVGFWSSVPAGATEGATNRLIEAKVSELDGHKSLYSDSFYTREEFDELYG
Mb3746|M.bovis_AF2122/97            NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
Rv3719|M.tuberculosis_H37Rv         NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
MMAR_5235|M.marinum_M               NIGFWSSVPAGATEGATNREIETKVSELNGHKSLYSDSYYTREEFDELYG
MUL_4310|M.ulcerans_Agy99           NIGFWSSVPAGATEGATNREIETKVSEVNGHKPLYSDSYYTREEFDELYG
MAB_0311c|M.abscessus_ATCC_199      NIGFWSSVPAGAVEGATNRLIERKVSELGGHKSLYSESFYTRDEFEPLYG
                                    *:*******.*  ** **: ** ::: : ***.***:::*: :**: ***

TH_2291|M.thermoresistible__bu      GETYKTVKKTYDPDGRLLDLYAKAVLRR
MSMEG_6283|M.smegmatis_MC2_155      GEVYNTVKKTYDPDSRLLDLYSKAVQRQ
Mflv_1284|M.gilvum_PYR-GCK          GEIYRTVKKTYDPDSRFLDLYAKAVRRQ
Mvan_5531|M.vanbaalenii_PYR-1       GETYKTVKKTYDPDSRFLDLYGKAVGRQ
MLBr_02333|M.leprae_Br4923          GESYNAVKKIYDPDSRLLDLYAKVVQRR
MAV_0384|M.avium_104                GEAYNTVKKTYDPDSRLLDLYAKAVQRR
Mb3746|M.bovis_AF2122/97            GETYNTVKKAYDPDSRLLDLYAKAVQRR
Rv3719|M.tuberculosis_H37Rv         GETYNTVKKAYDPDSRLLDLYAKAVQRR
MMAR_5235|M.marinum_M               GESYKTVKKTYDPDSRLLDLYAKAVQRR
MUL_4310|M.ulcerans_Agy99           GESYKTVKKTYDPDSRLLDLYAKAVQRR
MAB_0311c|M.abscessus_ATCC_199      GEHYQTLKKTYDPDNRLLDLYAKAVRRQ
                                    ** *.::** ****.*:****.*.* *: