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HGLLSKTRVYLVPVLGSALSAHQAGVDRLLESYRSIPATSAVRLAKPSSNLFRARTKRDAPGLDTSGLTG VLGVDPETRTADVAGMCTYEDLVAATLPYGLSPLVVPQLKTITLGGAVSGLGIESASFRNGLPHESVLEM DILTGAGELLTASRTQHADLFRAFPNSYGTLGYSTRLRIELEPVAPFVTLRHIRFHALADLIAAAERIID TGGHAGTPVDYLDGVVFSADESYLCVGRRTTTPGPVSDYTGQHIYYQSIRHDSPGDEPTKDDRLTMHDYF WRWDTDWFWCSRAFGVQNPRVRRWWPRRYRRSSVYSKLVSLDRRLRISDRIEARNGRPPRERVVQDVELP VERTLEFLEWFLETVPITPIWLCPLRLRDHDGWPLYPMRPDHTYVNVGFWSSVPAGATEGATNRLIEAKV SELDGHKSLYSDSFYTREEFDELYGGEAYNTVKKTYDPDSRLLDLYAKAVQRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0384 | - | - | 100% (474) | FAD/FMN-containing dehydrogenase |
| M. avium 104 | MAV_0232 | - | 2e-06 | 30.00% (130) | oxidoreductase, FAD-binding |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3746 | - | 0.0 | 79.32% (474) | hypothetical protein Mb3746 |
| M. gilvum PYR-GCK | Mflv_1284 | - | 0.0 | 75.44% (456) | FAD linked oxidase domain-containing protein |
| M. tuberculosis H37Rv | Rv3719 | - | 0.0 | 79.32% (474) | hypothetical protein Rv3719 |
| M. leprae Br4923 | MLBr_02333 | - | 0.0 | 81.21% (463) | hypothetical protein MLBr_02333 |
| M. abscessus ATCC 19977 | MAB_0311c | - | 0.0 | 73.57% (454) | hypothetical protein MAB_0311c |
| M. marinum M | MMAR_5235 | - | 0.0 | 80.38% (474) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6283 | - | 0.0 | 76.34% (465) | FAD binding domain-containing protein |
| M. thermoresistible (build 8) | TH_2291 | - | 0.0 | 74.73% (463) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4310 | - | 0.0 | 81.12% (445) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5531 | - | 0.0 | 76.75% (456) | FAD linked oxidase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1284|M.gilvum_PYR-GCK -----------MSVAVTDARAAHAHGVQRLLASYRAIPADATVRLAKPTS
Mvan_5531|M.vanbaalenii_PYR-1 -----------MSVPSTDARSAHADGVQRLLASYRAIPQDATVRLAKPTS
MSMEG_6283|M.smegmatis_MC2_155 -----------MSVVTTDAQAAHAAGVSRLLASYRAIPPSATVRLAKPTS
TH_2291|M.thermoresistible__bu --------------VTTDARAAHAAGVRRLLESYRAIPPDATVRLAKPTS
Mb3746|M.bovis_AF2122/97 MQGQLSRTRVYAVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
Rv3719|M.tuberculosis_H37Rv MQGQLSRTRVYTVPVPGSAQSAYACGVERLLASYRSIPATASIRLAKPTS
MAV_0384|M.avium_104 MHGLLSKTRVYLVPVLGSALSAHQAGVDRLLESYRSIPATSAVRLAKPSS
MLBr_02333|M.leprae_Br4923 -----------MVSVQESALVVYTSGVKRLVASYRSIPATSPVRLAKPTS
MMAR_5235|M.marinum_M MQGLWSVTTIYVVPGTGSGLSAHTSGVERLLASYRSIPTTATVRLAKPTS
MUL_4310|M.ulcerans_Agy99 -----------------------------MLASYRSIPTTATVRLAKPTS
MAB_0311c|M.abscessus_ATCC_199 --------------MPIASGSAHAEGVNRLLRSYRAIPTTATVRLAKPTS
:: ***:** :.:*****:*
Mflv_1284|M.gilvum_PYR-GCK NLFRARVENTGRGLDTSGLTHVIAVDPDARTADVAGMCTYEDLVAATLPY
Mvan_5531|M.vanbaalenii_PYR-1 NLFRARAKTRTKGLDTSGLTNVIAVDAEARTADVAGMCTYEDLVAATLPH
MSMEG_6283|M.smegmatis_MC2_155 NLFRARARTNVKGLDVSGLTGVIGVDPDARTADVAGMCTYEDLVAATLPY
TH_2291|M.thermoresistible__bu NLFRARAKNTVRGLDVSGLTDVIAVDPQTRTAEVAGMCTYEDLVAATLPY
Mb3746|M.bovis_AF2122/97 NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
Rv3719|M.tuberculosis_H37Rv NLFRARVKHDARGLDASGLTGVIGIDPEARTADVAGMCTYEDLIAATLHY
MAV_0384|M.avium_104 NLFRARTKRDAPGLDTSGLTGVLGVDPETRTADVAGMCTYEDLVAATLPY
MLBr_02333|M.leprae_Br4923 NLFRTRAKRDAPGLDASGLTGVIGIDTEARTADVAGMCTYEDLVAATLPY
MMAR_5235|M.marinum_M NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MUL_4310|M.ulcerans_Agy99 NLFRARAKRDVRGLDTSGLTGVISIDPDARTADVAGMCTYEDLVAATLPH
MAB_0311c|M.abscessus_ATCC_199 NLFRARAKPTTPGLDTSGLTGVIDVDPVNRTAEVAGMCTYEDLVAATLAH
****:*.. ***.**** *: :*. ***:**********:**** :
Mflv_1284|M.gilvum_PYR-GCK GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGTGDI
Mvan_5531|M.vanbaalenii_PYR-1 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGTGDV
MSMEG_6283|M.smegmatis_MC2_155 GLAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDILTGSGEI
TH_2291|M.thermoresistible__bu ALAPLVVPQLKTITLGGAVTGLGIESTSFRNGLPHESVLEMDVLTGAGEV
Mb3746|M.bovis_AF2122/97 GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
Rv3719|M.tuberculosis_H37Rv GLSPLVVPQLRTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MAV_0384|M.avium_104 GLSPLVVPQLKTITLGGAVSGLGIESASFRNGLPHESVLEMDILTGAGEL
MLBr_02333|M.leprae_Br4923 GLLPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MMAR_5235|M.marinum_M GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGAGEL
MUL_4310|M.ulcerans_Agy99 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDVLTGAGEL
MAB_0311c|M.abscessus_ATCC_199 GLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGSGEI
.* *******:********:******:***************:***:*::
Mflv_1284|M.gilvum_PYR-GCK VRASADENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLP
Mvan_5531|M.vanbaalenii_PYR-1 VRASPDENPDLFRAFPNSYGTLGYSVRLKIELEPVKPFVALRHLRFHSLS
MSMEG_6283|M.smegmatis_MC2_155 VTASPDQHSDLFHAFPNSYGTLGYSTRLRIELEPVHPFVALRHLRFHSIT
TH_2291|M.thermoresistible__bu LTTSPTRHPDLFRAFPNSYGTLGYAVRLKIELEPVRPFVAIRHLRFGSVP
Mb3746|M.bovis_AF2122/97 LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
Rv3719|M.tuberculosis_H37Rv LTVSPGQHSDLYRAFPNSYGTLGYSTRLRIQLEPVRPFVALRHIRFSSLT
MAV_0384|M.avium_104 LTASRTQHADLFRAFPNSYGTLGYSTRLRIELEPVAPFVTLRHIRFHALA
MLBr_02333|M.leprae_Br4923 LTVSANQHGDLYRAFPNSYGTLGYSTRFRISLEPVTPFVALRHIRFHLLT
MMAR_5235|M.marinum_M LTVSADRHADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MUL_4310|M.ulcerans_Agy99 LTVSADRNADLYRAFPNSYGTLGYSTRLKILLEPVKPFVALQHIRFDSLR
MAB_0311c|M.abscessus_ATCC_199 VTAAPDRLADLYRGFPNSYGTLGYSVRLRIQLEPVKPFVALRHIRFHSLE
: .: . **::.**********:.*::* **** ***:::*:** :
Mflv_1284|M.gilvum_PYR-GCK NLIAAMDRIVETGGWNGDQVDYLDGVVFSADESYLCVGIQSATPGPVSDY
Mvan_5531|M.vanbaalenii_PYR-1 ALIEAMDRIVETGGLNGEPVDYLDGVVFSAEESYLCVGQRSATPGPVSDY
MSMEG_6283|M.smegmatis_MC2_155 DLVAAMDRIIETGGLDGEPVDYLDGVVFSATESYLCVGFKTKTPGPVSDY
TH_2291|M.thermoresistible__bu DLVAEMDRIIAAGEYDGIPVDYLDGVVFSAQESYLTLGFKTTTPGPVSDY
Mb3746|M.bovis_AF2122/97 AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
Rv3719|M.tuberculosis_H37Rv AMVAAMERIIDTGGLDGESVDYLDGVVFSADESYLCIGMQTSVPGPVSDY
MAV_0384|M.avium_104 DLIAAAERIIDTGGHAGTPVDYLDGVVFSADESYLCVGRRTTTPGPVSDY
MLBr_02333|M.leprae_Br4923 EMVTAMENIIDTGGHDGVPVDYLDGVVFSANESYLCIGKRTTTPGPVSDY
MMAR_5235|M.marinum_M ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MUL_4310|M.ulcerans_Agy99 ALVAAMERIVDTGGLDGMAVDYLDGVVFSADESYLCVGVRTATPGPVSDY
MAB_0311c|M.abscessus_ATCC_199 ELVSVMESIVNTAAYEGESVDYLDGVVFAADECYLSLGALTAAPGPVSDY
:: : *: :. * *********:* *.** :* : .*******
Mflv_1284|M.gilvum_PYR-GCK TGDDIFYRSIQHDSPTDGGEKHDRLTVHDYFWRWDTDWFWCSRAFGAQNP
Mvan_5531|M.vanbaalenii_PYR-1 TGKQIYYRSIQHDGPTDGAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQNP
MSMEG_6283|M.smegmatis_MC2_155 TGQQIFYRSIQHDGDT-GAEKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
TH_2291|M.thermoresistible__bu TGQQIYYRSIQHAEG----VKHDRLTIHDYLWRWDTDWFWCSRAFGAQHP
Mb3746|M.bovis_AF2122/97 TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
Rv3719|M.tuberculosis_H37Rv TGQDIYYRSIQHEAG----IKEDRLTIHDYFWRWDTDWFWCSRSFGAQNP
MAV_0384|M.avium_104 TGQHIYYQSIRHDSPGDEPTKDDRLTMHDYFWRWDTDWFWCSRAFGVQNP
MLBr_02333|M.leprae_Br4923 TGQHIYYRSIQHDN----EVKEDRLTIHDYVWRWDTDWFWCSRAFGAQNQ
MMAR_5235|M.marinum_M TGKDIYYRSIQHESG----IKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MUL_4310|M.ulcerans_Agy99 TGKDIYYRSIQHESG----VKADRLTTHDYFWRWDTDWFWCSRAFGAQNP
MAB_0311c|M.abscessus_ATCC_199 TGQRVYYRSIQHPDG----ISNDRLTIHDYLWRWDTDWFWCSRAFGAQNP
**. ::*:**:* . **** ***.************:**.*:
Mflv_1284|M.gilvum_PYR-GCK KIRRWWPRRYRRSSFYWKLIGYDQRFGIADRIEKRAGRPLRERVVQDVEV
Mvan_5531|M.vanbaalenii_PYR-1 RIRRWWPRRYRRSSVYWKLIGYDRRFGIADRIEKRNGRPPRERVVQDIEV
MSMEG_6283|M.smegmatis_MC2_155 VIRRFWPRRLRRSSFYWKLVAYDQRYDIADRIEKRNGRPPRERVVQDVEV
TH_2291|M.thermoresistible__bu TIRRLWPRRLRRSSFYWKLISYDQRFGIADRIERWNGRPPRERVVQDIEV
Mb3746|M.bovis_AF2122/97 RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
Rv3719|M.tuberculosis_H37Rv RLRRWWPRRYRRSSVYWRLMALDQRFGIADRFENSRGRPARERVVQDIEV
MAV_0384|M.avium_104 RVRRWWPRRYRRSSVYSKLVSLDRRLRISDRIEARNGRPPRERVVQDVEL
MLBr_02333|M.leprae_Br4923 QLRRWWPRRYRRSSVYWKLMAADRRFGIVDRIEARNGRPLRERVVQDVEL
MMAR_5235|M.marinum_M TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MUL_4310|M.ulcerans_Agy99 TLRRWWPRRYRRSSAYWKLVELDQRFGIADRIEKRHGRPPRERVVQDVEV
MAB_0311c|M.abscessus_ATCC_199 GIRRLWPRKYRRSSVYWKLIALDQRYDIADRIERFNGRPARERVVQDVEV
:** ***: **** * :*: *:* * **:* *** *******:*:
Mflv_1284|M.gilvum_PYR-GCK PIERTVEFLQWFLGTIPIEPIWLCPLRLR----DDNSWSLYPLRPHRTYV
Mvan_5531|M.vanbaalenii_PYR-1 PIERTVEFLQWFLDTVPIEPIWLCPLRLR----DDRDWPLYPIRPHHTYV
MSMEG_6283|M.smegmatis_MC2_155 PIERCADFVEWFLQNVPIEPIWLCPLRLRDSADGGASWPLYPLKAHHTYV
TH_2291|M.thermoresistible__bu PLERCAEFIDWFLEYIPIEPIWLCPLRLR-STDPDGVWPLYPLRPGRTYV
Mb3746|M.bovis_AF2122/97 PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
Rv3719|M.tuberculosis_H37Rv PIERTCEFLEWFGENVPISPIWLCPLRLR----DHAGWPLYPIRPDRSYV
MAV_0384|M.avium_104 PVERTLEFLEWFLETVPITPIWLCPLRLR----DHDGWPLYPMRPDHTYV
MLBr_02333|M.leprae_Br4923 PIERTCEFLEWFLGSVPIAPIWLCPLRLR----DHNSWPLYPIQPDHSYV
MMAR_5235|M.marinum_M PIERTQDFVTWFLETVPIAPIWLCPLRLR----DNDGWPLYPIRPDHSYV
MUL_4310|M.ulcerans_Agy99 PIERTQDFMTWFLETVPIAPIWLCPLRLR----DSDGWPLYPIRPDHSYV
MAB_0311c|M.abscessus_ATCC_199 PISRTPEFLRWFLDEIPIEPVWVCPLRLR----DSEGWPLYPIRPGQTYV
*:.* :*: ** :** *:*:****** *.***::. ::**
Mflv_1284|M.gilvum_PYR-GCK NVGFWSSVPVGPEEGHTNKLIERRISELEGHKSLYSDAFYSADEFDALYG
Mvan_5531|M.vanbaalenii_PYR-1 NVGFWSSVPVGPEEGYTNRMIERKVSDLDGHKSLYSDAYYSPEEFDSLYG
MSMEG_6283|M.smegmatis_MC2_155 NIGFWSSVPVGPEEGHTNRLIEKKVAELDGHKSLYSDAYYTRDEFDELYG
TH_2291|M.thermoresistible__bu NIGFWSSVPAGDTEGATNRLIERKVSELDGHKSLYSDAFYSPDEFDELYG
Mb3746|M.bovis_AF2122/97 NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
Rv3719|M.tuberculosis_H37Rv NIGFWSSVPVGATEGATNRKIENKVSALDGHKSLYSDSFYTREEFDELYG
MAV_0384|M.avium_104 NVGFWSSVPAGATEGATNRLIEAKVSELDGHKSLYSDSFYTREEFDELYG
MLBr_02333|M.leprae_Br4923 NVGFWSSVPAGATEGETNRTIEAKVSALDGHKSLYSDSFYTREEFNELYG
MMAR_5235|M.marinum_M NIGFWSSVPAGATEGATNREIETKVSELNGHKSLYSDSYYTREEFDELYG
MUL_4310|M.ulcerans_Agy99 NIGFWSSVPAGATEGATNREIETKVSEVNGHKPLYSDSYYTREEFDELYG
MAB_0311c|M.abscessus_ATCC_199 NIGFWSSVPAGAVEGATNRLIERKVSELGGHKSLYSESFYTRDEFEPLYG
*:*******.* ** **: ** ::: : ***.***:::*: :**: ***
Mflv_1284|M.gilvum_PYR-GCK GEIYRTVKKTYDPDSRFLDLYAKAVRRQ
Mvan_5531|M.vanbaalenii_PYR-1 GETYKTVKKTYDPDSRFLDLYGKAVGRQ
MSMEG_6283|M.smegmatis_MC2_155 GEVYNTVKKTYDPDSRLLDLYSKAVQRQ
TH_2291|M.thermoresistible__bu GETYKTVKKTYDPDGRLLDLYAKAVLRR
Mb3746|M.bovis_AF2122/97 GETYNTVKKAYDPDSRLLDLYAKAVQRR
Rv3719|M.tuberculosis_H37Rv GETYNTVKKAYDPDSRLLDLYAKAVQRR
MAV_0384|M.avium_104 GEAYNTVKKTYDPDSRLLDLYAKAVQRR
MLBr_02333|M.leprae_Br4923 GESYNAVKKIYDPDSRLLDLYAKVVQRR
MMAR_5235|M.marinum_M GESYKTVKKTYDPDSRLLDLYAKAVQRR
MUL_4310|M.ulcerans_Agy99 GESYKTVKKTYDPDSRLLDLYAKAVQRR
MAB_0311c|M.abscessus_ATCC_199 GEHYQTLKKTYDPDNRLLDLYAKAVRRQ
** *.::** ****.*:****.*.* *: