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MHELPVEVSVNGQTYQGQVEPRVTLADFLRENCGLTGTHLGCEHGACGACTVLLDGQAVRSCLIFAVQVD GQDVTTVEGIAEPDGCLSPVQAALKECHGLQCGFCTPGFVTSITALLRDNPAPTDEEIREGLSGNFCRCT GYQGIINAVHRAAELSTGEAQRDLEVHAQQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5883 | - | - | 100% (170) | 2Fe-2S-binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0745 | - | 1e-44 | 51.90% (158) | 2Fe-2S-binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2464 | - | 9e-43 | 55.92% (152) | 2Fe-2S-binding domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0381c | - | 3e-43 | 49.37% (158) | carbon monoxyde dehydrogenase small subunit |
| M. gilvum PYR-GCK | Mflv_1570 | - | 4e-78 | 86.36% (154) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0374c | - | 3e-43 | 49.37% (158) | carbon monoxyde dehydrogenase small subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 4e-22 | 40.56% (143) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_0621 | coxS_3 | 2e-71 | 79.35% (155) | carbon monoxyde dehydrogenase (small chain), CoxS_3 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1272 | - | 9e-71 | 77.27% (154) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) |
| M. ulcerans Agy99 | MUL_0116 | coxS | 1e-40 | 49.01% (151) | carbon monoxyde dehydrogenase (small chain), CoxS |
| M. vanbaalenii PYR-1 | Mvan_5186 | - | 5e-80 | 89.61% (154) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0381c|M.bovis_AF2122/97 ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
Rv0374c|M.tuberculosis_H37Rv ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
MUL_0116|M.ulcerans_Agy99 ---MQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
Mflv_1570|M.gilvum_PYR-GCK MHEIPVEVSVNGRRYAATVEPRLTLADYLREKCGLTGTHLGCEHGACGAC
Mvan_5186|M.vanbaalenii_PYR-1 MHELPVEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTHLGCEHGACGAC
MSMEG_5883|M.smegmatis_MC2_155 MHELPVEVSVNGQTYQGQVEPRVTLADFLRENCGLTGTHLGCEHGACGAC
MMAR_0621|M.marinum_M MHERSVQLSVNGNHVAARVEPRMTLADFLRERCGLTGTHLGCEHGACGAC
TH_1272|M.thermoresistible__bu VHDHQVELTVNGQRTSAPVESRLTLADFLRERCGLTGTHLGCEHGACGAC
MAB_2925c|M.abscessus_ATCC_199 -------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGDCGAC
:.***. . .. * :**:. . .: **: . **:*
Mb0381c|M.bovis_AF2122/97 VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
Rv0374c|M.tuberculosis_H37Rv VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
MUL_0116|M.ulcerans_Agy99 VVDVDGVPVKSCTMPAVMASGRSIRTVEGLAVADGSLDPVQEGFMRCHGL
Mflv_1570|M.gilvum_PYR-GCK TALLDGQAVRACLVFAVQVDGQEVTTVEGIAGENGELSPVQAAMKECHGL
Mvan_5186|M.vanbaalenii_PYR-1 TVLLDGQAVRSCLIFAVQVDGQEVTTVEGIAGEDGELSPVQAAMRECHGL
MSMEG_5883|M.smegmatis_MC2_155 TVLLDGQAVRSCLIFAVQVDGQDVTTVEGIAEPDGCLSPVQAALKECHGL
MMAR_0621|M.marinum_M TVLVGGDAVRSCLLFAVQADGAEVTTVEGIASADGELSPVQSALRECHGL
TH_1272|M.thermoresistible__bu TVIMDGAAVRSCLVFAVQADGSEVTTVEGIASPDGELSPVQQAMRDCHGL
MAB_2925c|M.abscessus_ATCC_199 TVLVDGASQHSCIVPAHRVTDAEIHTVRSLAG-EHDLHPMQRGFIDHAGF
.. :.* . ::* : * . . .: **..:* : * *:* .: *:
Mb0381c|M.bovis_AF2122/97 QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
Rv0374c|M.tuberculosis_H37Rv QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
MUL_0116|M.ulcerans_Agy99 QCGFCTPGMMITARALLDRNLDPDEETIREAISGQICRCTGYTTIVRSIQ
Mflv_1570|M.gilvum_PYR-GCK QCGFCTPGFVTSITALLRDNPAPTDTEIREGLSGNFCRCTGYQGIVNAVK
Mvan_5186|M.vanbaalenii_PYR-1 QCGFCTPGFVTSITALLRDNPNPSDEEIREGLSGNFCRCTGYQGIVNAVK
MSMEG_5883|M.smegmatis_MC2_155 QCGFCTPGFVTSITALLRDNPAPTDEEIREGLSGNFCRCTGYQGIINAVH
MMAR_0621|M.marinum_M QCGFCTPGFVVSITALLRDNPDPTDEQIREGLSGNFCRCTGYQGIVAATR
TH_1272|M.thermoresistible__bu QCGFCTPGFVTTITAMLQENPDPTDEEIREGLSGNFCRCTGYQGIIKAVR
MAB_2925c|M.abscessus_ATCC_199 QCGFCTAGMVLTAATLTGDQT----EDLGNALKGNLCRCTGYRPIRDAVC
******.*:: : :: : : :.:.*::****** * :
Mb0381c|M.bovis_AF2122/97 ------------WAAAHQTVKAQS--------------------------
Rv0374c|M.tuberculosis_H37Rv ------------WAAAHQTVKAQS--------------------------
MUL_0116|M.ulcerans_Agy99 ------------WAAKNAKEVASS--------------------------
Mflv_1570|M.gilvum_PYR-GCK ------------RAAET-TG------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 ------------RAAET-TG------------------------------
MSMEG_5883|M.smegmatis_MC2_155 ------------RAAELSTGEAQRDLEVHAQQ------------------
MMAR_0621|M.marinum_M ------------RASELMSQ------------------------------
TH_1272|M.thermoresistible__bu ------------QAAEAMRA------------------------------
MAB_2925c|M.abscessus_ATCC_199 GVVPPRGSVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITR
*:
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 IDTDRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRF
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 AGQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 KGLGARIADPARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQH
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAP
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RVGGGFGAKQEMLTEDLVLLAVRVTGAPVVYEFTRSDQFTIAPCRHPMRV
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANK
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RVDAQAVYTNNIPSGAFRGYGLGQVLFGIESALDELARNLGIDPFEFRRR
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPARNGSD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 LPAGWKVGEGMAIAMIATVPPRGHVADARAELDARGRYRISVGSAEFGNG
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 TTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAFGSAGTTVAGLAVY
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGADLLGLTEIAASAPE
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PLSAVGHHEGTPRSVAFNVQAFRVAVRPQTGTVRILQSVQTADAGVVVNP
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QQCRGQVEGGVAQAIGSALYEEILVHDGFVSTTALRNYHIPRLVDVPDTE
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5883|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VYFADTYDTFGPLGAKSMSESPYNPVAPALANAIRDAVGVRVYRLPMNAA
Mb0381c|M.bovis_AF2122/97 ---------------
Rv0374c|M.tuberculosis_H37Rv ---------------
MUL_0116|M.ulcerans_Agy99 ---------------
Mflv_1570|M.gilvum_PYR-GCK ---------------
Mvan_5186|M.vanbaalenii_PYR-1 ---------------
MSMEG_5883|M.smegmatis_MC2_155 ---------------
MMAR_0621|M.marinum_M ---------------
TH_1272|M.thermoresistible__bu ---------------
MAB_2925c|M.abscessus_ATCC_199 RVWRVINDSGGGESS