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M. smegmatis MC2 155 MSMEG_5862 (-)

annotation: short chain dehydrogenase
coordinates: 5928485 - 5929312
length: 275

MARFEPHPARRPAIVAGASSGIGAATATELAAHGFPVALGARRVEKCQELVDQITARGGEAVALPLDVTD
ADSVKSFVHAATEALGDIEVLIAGAGDTDFGRLHEISTEEFEQQVQIHLIGANRMATAVLPGMVERRRGD
VIFVGSDVSLRQRPHMGAYGAAKAGLLAMVNNLQMELEGTGVRASIVHPGPTRTSMGWSLPAEKIGPALE
DWAKWGQARHDYFLRAADLARAITFVAETPRGGFIANLEIQPEAPLAEVTDRQKLALGEEGMPNQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5862--100% (275)short chain dehydrogenase
M. smegmatis MC2 155MSMEG_3581-4e-2732.93% (249) FabG protein
M. smegmatis MC2 155MSMEG_4722-4e-2636.41% (195) short-chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0788c-1e-11775.91% (274) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1597-1e-12580.29% (274) short chain dehydrogenase
M. tuberculosis H37RvRv0765c-1e-11775.91% (274) short chain dehydrogenase
M. leprae Br4923MLBr_00429-6e-2534.87% (195) putative oxidoreductase
M. abscessus ATCC 19977MAB_1215c-1e-11471.27% (275) short chain dehydrogenase
M. marinum MMMAR_4931-1e-12982.22% (270) short-chain alcohol dehydrogenase
M. avium 104MAV_0709-1e-12781.09% (275) short chain dehydrogenase
M. thermoresistible (build 8)TH_1257-1e-12884.07% (270) short chain dehydrogenase
M. ulcerans Agy99MUL_0474-1e-12680.37% (270) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5160-1e-12480.51% (272) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0788c|M.bovis_AF2122/97           MPRFEPHPARRTTVVAGASSGIGAATATELAGRGFPVALGARRMDKLAEL
Rv0765c|M.tuberculosis_H37Rv        MPRFEPHPARRTTVVAGASSGIGAATATELAGRGFPVALGARRMDKLAEL
MAB_1215c|M.abscessus_ATCC_199      MPRFEPHPARRPSIIAGASSGIGAATAIELAGRGFPVALGARRVDKLTEL
MMAR_4931|M.marinum_M               MPRFQPHPDRRPAIVAGASSGIGAATAVELAAHGFPVALGARRVQKCEEI
MUL_0474|M.ulcerans_Agy99           MPRFQPHPDRRPAIVAGASPGIGAATAVDLAAHGFPDALGARRVQKCEKI
TH_1257|M.thermoresistible__bu      MPRFDPHPERRPAIVAGASSGIGAATAKELAARGFPVALGARRVEKCEEL
Mflv_1597|M.gilvum_PYR-GCK          MPRFDPLPDRRPALVAGASSGIGEATAIRLAANGFPVALGARRVEKLEEI
Mvan_5160|M.vanbaalenii_PYR-1       MPRFDPLPDRRPALVAGASSGIGEATAIALAAHGFPVALGARRVEKCQEI
MAV_0709|M.avium_104                MPRFDPLPERRPAIVAGASSGIGEATAIELAAHGFPVALGARRVEKLNDI
MSMEG_5862|M.smegmatis_MC2_155      MARFEPHPARRPAIVAGASSGIGAATATELAAHGFPVALGARRVEKCQEL
MLBr_00429|M.leprae_Br4923          MPIPAPSPEAR-AVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDL
                                    *.   * *  * ::::*** .** * *  **..*..  : *** :   .:

Mb0788c|M.bovis_AF2122/97           VDKIRADGGEAVAF-PLDVTDPESVKSFVAQTVEALGEVELLVSSAGDML
Rv0765c|M.tuberculosis_H37Rv        VDKIRADGGEAVAF-PLDVTDPESVKSFVAQTVEALGEVELLVSSAGDML
MAB_1215c|M.abscessus_ATCC_199      VEKIRSDGGEAVAF-PLDVTDADSVKSFVAESIDALGEIDLLVSGAGDMY
MMAR_4931|M.marinum_M               VEKIRADGGDAVAL-ALDVTDADSVKDFVHQATERLGDIEVLVAGAGDTY
MUL_0474|M.ulcerans_Agy99           VEKIRADGGDAVAL-ALDVTDADSVKDFVHQATERLGDIEVLVAGAGDTY
TH_1257|M.thermoresistible__bu      VEQIRADGGEAVAL-HLDVTDPDSVKSFVHGAAEKLGDIEVLVAGAGDTF
Mflv_1597|M.gilvum_PYR-GCK          VGKIRADGGEAIAV-HLDVTEPDSVKAAVEQTTSQLGDIEVLVAGAGDTY
Mvan_5160|M.vanbaalenii_PYR-1       VDKIRADGGEAIAV-HLDVTDPDSVKSAVEQTTVELGEIEVLVAGAGDTY
MAV_0709|M.avium_104                VGKINADGGEAVGF-HLDVTDPNSVKSFVAQAVDALGDIEVLVAGAGDTY
MSMEG_5862|M.smegmatis_MC2_155      VDQITARGGEAVAL-PLDVTDADSVKSFVHAATEALGDIEVLIAGAGDTD
MLBr_00429|M.leprae_Br4923          AARLADKYRVAVEVRPADLTDPSERVKLADELTVRP--ISILCANAGTAT
                                    . ::      *: .   *:*:...    .         :.:* :.**   

Mb0788c|M.bovis_AF2122/97           PGQLHEVSTEAFAEQVQIHLVGANRLATAVLPAMVARRRGDLIFVGSDVG
Rv0765c|M.tuberculosis_H37Rv        PGQLHEVSTEAFAEQVQIHLVGANRLATAVLPAMVARRRGDLIFVGSDVG
MAB_1215c|M.abscessus_ATCC_199      PGRVHEMSAATFAAQIQVHLLGANQLATEVVPDMVSRRRGDVVFIGSDVA
MMAR_4931|M.marinum_M               FGRLYEIDTETFESQVQIHLIGANRLATAVLPGMLERQRGDLIFVGSDVA
MUL_0474|M.ulcerans_Agy99           FGRLYEIDTETFESQVQIHLIGANRLATAVLPGMLERQRGDLIFVGSDVA
TH_1257|M.thermoresistible__bu      FGRLHEISTEEFESQVQIHLIGANRLATAVLPGMVERRRGDLIFVGSDVA
Mflv_1597|M.gilvum_PYR-GCK          FGKLDSISTEQFESQIQIHLIGANRVAGAVLPGMIERRRGDLIFVGSDVA
Mvan_5160|M.vanbaalenii_PYR-1       FGKLDAISTEEFESQIQIHLIGANRVATAVLPGMIERRRGDLIFVGSDVA
MAV_0709|M.avium_104                FGKLAEIAGDEFESQLQIHLVGAFRLASAVLPGMLERQRGDLIFVGSDVA
MSMEG_5862|M.smegmatis_MC2_155      FGRLHEISTEEFEQQVQIHLIGANRMATAVLPGMVERRRGDVIFVGSDVS
MLBr_00429|M.leprae_Br4923          FGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAG
                                     * :  :       *:*:: :..  ::  *:* *: *: *.::: ** ..

Mb0788c|M.bovis_AF2122/97           LRQRPHMGAYGAAKAGLAAMVTNLQMELEGTGVRASIVHPGPTLTGMGWQ
Rv0765c|M.tuberculosis_H37Rv        LRQRPHMGAYGAAKAGLAAMVTNLQMELEGTGVRASIVHPGPTLTGMGWQ
MAB_1215c|M.abscessus_ATCC_199      LHQRPHMGAYGAAKAALLAMVNTMRMELEGTGVRASIVHPGPTLTSMGWQ
MMAR_4931|M.marinum_M               LRQRPHMGAYGAAKAALVAMVTNLQMELEGTGLRASIVHPGPTKTAMGWS
MUL_0474|M.ulcerans_Agy99           LRQRPHMGAYGAAKAALVAMVTNLQMELEGTGLRASIVHPGRTKTAMGWS
TH_1257|M.thermoresistible__bu      LRQRPHMGGYGAAKAGLLAMVHNLQMELEGTGVRASIVHPGPTKTAMGWS
Mflv_1597|M.gilvum_PYR-GCK          LRQRPHMGAYGAAKAALVAMVTNYQMELEGTGVRASIVHPGPTKTSMGWS
Mvan_5160|M.vanbaalenii_PYR-1       LRQRPHMGAYGAAKAALVAMVTNYQMELEGTGVRASIVHPGPTKTAMGWS
MAV_0709|M.avium_104                LRQRPHMGAYGAAKAALVAMVNNFQMELEGTGVRASVVHPGPTKTAMGWS
MSMEG_5862|M.smegmatis_MC2_155      LRQRPHMGAYGAAKAGLLAMVNNLQMELEGTGVRASIVHPGPTRTSMGWS
MLBr_00429|M.leprae_Br4923          NSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDH
                                        *: . *.*:**   ::  . : **.*:*::.::: ** . * :   

Mb0788c|M.bovis_AF2122/97           LSAEQVGPMLADWAKWGQARHNYFLRPSDLAR-AIAFVAETPRGCVVVNM
Rv0765c|M.tuberculosis_H37Rv        LSAEQVGPMLADWAKWGQARHNYFLRPSDLAR-AIAFVAETPRGCVVVNM
MAB_1215c|M.abscessus_ATCC_199      LSAEQVGPMLEDWKSWGQARHSYFLRPSDIAR-AVTFVAETPRGAHIPEM
MMAR_4931|M.marinum_M               LPVESIGPALEDWAKWGQARHDYFLRASDIAR-AITFVAETPRGGFVANM
MUL_0474|M.ulcerans_Agy99           LPVESIGPALEDWAKWGQARHDYFLRASDIAR-AITFVAETPRGGFVANM
TH_1257|M.thermoresistible__bu      LPPDRIEQALNDWAKWGQARHDYFLRASDLAR-AIAFVAETPRGGFIANM
Mflv_1597|M.gilvum_PYR-GCK          LPAELIGPALEDWAKWGQARHDYFLRADDLAR-AITFVAETPRGGFIANM
Mvan_5160|M.vanbaalenii_PYR-1       LPAELIGPALEDWAKWGQARHDYFLRAADLAR-AITFVAETPRGGFIASM
MAV_0709|M.avium_104                LPAEKIGPALEDWAKWGQARHDYFLRAADLAR-AITFVAETPRGGFIANM
MSMEG_5862|M.smegmatis_MC2_155      LPAEKIGPALEDWAKWGQARHDYFLRAADLAR-AITFVAETPRGGFIANL
MLBr_00429|M.leprae_Br4923          DEASLVEKLVPDFL-WISTEHTARLSLDALERNKMRVVPGLTSKAMSVAS
                                       . :   : *:  * .:.*   *    : *  : .*.  .        

Mb0788c|M.bovis_AF2122/97           EIQPEAPLRDAPAHRQKLVLGEEGMPG-
Rv0765c|M.tuberculosis_H37Rv        EIQPEAPLRDAPAHRQKLVLGEEGMPG-
MAB_1215c|M.abscessus_ATCC_199      EVQPEAPLKDAPADKQKLELGEEGMPS-
MMAR_4931|M.marinum_M               ELQPEAPLAATTN-RQQLKVDEKAKDS-
MUL_0474|M.ulcerans_Agy99           ELQPEAPLAATTN-RQQLKVDEKAKDS-
TH_1257|M.thermoresistible__bu      ELQPEAPLADAPKERQQLTYPETS----
Mflv_1597|M.gilvum_PYR-GCK          ELQPEAPLSEAKD-RQKLALGEEGMPS-
Mvan_5160|M.vanbaalenii_PYR-1       ELQPEAPLASVKD-RQQLKVDKEALNS-
MAV_0709|M.avium_104                ELQPEAPLADNKD-RQKLALGEEGMPGQ
MSMEG_5862|M.smegmatis_MC2_155      EIQPEAPLAEVTD-RQKLALGEEGMPNQ
MLBr_00429|M.leprae_Br4923          RYAPRAIVASIVG-NFYKKLGGG-----
                                    .  *.* :      .