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CLIEPARITISAFLNALMLRRSMTSRQLRERSGKSDSLRFFSGSFRCARAHIRTAYEGIFMEVAARSRLL AGAAIIGAGALVAAPIQPVPDVIAAPVIQSATPAVEMTALVNPIELWSAVISQAIANTGAIANTVLENPI PIAHKVIDNQLITADVLTSFVALFGEGFVASAGGVPAALQSAVEQILAGEIYSGVENYAIAILTPVVEGA LGALGQLDDISAVLQNPFLNAANVVGTVVSVPTLIGAGLPILFEALSPILQVGLTAQGVYDGVTAGDLEA VANALISFPSDMAGTILNGNPTIGNSGLLGSELGLIPSLLTVRQSIADAIQPPAVSTLVGAKMESAPEVN SFTFTVDEDGELGEVTKSTTESGTTEGNGIQAIAAKSADAEDDATTGTGTETEPEKSEKPVEKSKKPLVT LGNKFSPTTTAGDKARPGQRAEAALKSIGNEVNKTVKKIGDGVKKALGVKGKKKADSKASSSSKDSAGSE D*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5578 | - | - | 100% (492) | hypothetical protein MSMEG_5578 |
M. smegmatis MC2 155 | MSMEG_5322 | - | 3e-42 | 30.50% (459) | hypothetical protein MSMEG_5322 |
M. smegmatis MC2 155 | MSMEG_6033 | - | 7e-17 | 24.22% (483) | hypothetical protein MSMEG_6033 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1679c | PE_PGRS30 | 2e-12 | 26.84% (272) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_1343 | - | 2e-19 | 27.68% (383) | hypothetical protein Mflv_1343 |
M. tuberculosis H37Rv | Rv1651c | PE_PGRS30 | 2e-12 | 26.84% (272) | PE-PGRS family protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3570 | - | 2e-10 | 25.00% (212) | PE-PGRS family protein |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_2715 | - | 4e-36 | 29.43% (435) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_1639 | - | 2e-10 | 26.65% (364) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_3971 | - | 1e-27 | 28.34% (374) | hypothetical protein Mvan_3971 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1679c|M.bovis_AF2122/97 MSFLLVEPDLVTAAAANLAGIRSALSEAAAAAS--TPTTALASAGADEVS Rv1651c|M.tuberculosis_H37Rv MSFLLVEPDLVTAAAANLAGIRSALSEAAAAAS--TPTTALASAGADEVS MMAR_3570|M.marinum_M MSYVIVAPEMLEAAASDLANIGSAIGVANAAAA--LPTTSVLAAAADEVS MUL_1639|M.ulcerans_Agy99 MSFLLVQPEMVSAATESLTAIRSALGEVSAAVA--GPTTAVVAAAGDEVS MSMEG_5578|M.smegmatis_MC2_155 -MCLIEPARITISAFLNALMLRRSMTSRQLRER--SGKSDSLRFFSGSFR TH_2715|M.thermoresistible__bu ---------VGATAVAVAPVLAPPSPPDIQVVT--TPFSS-----TEVHL Mflv_1343|M.gilvum_PYR-GCK -----MRAGVRSCLTASVALVGAGAIAITPVNP--LTTDVLPITQHAVSL Mvan_3971|M.vanbaalenii_PYR-1 -----MHVAVRSPLATGVALVGAGAIALTPVHPSLPDISVPAVSSMAVQL : : Mb1679c|M.bovis_AF2122/97 AAVSRLFGAYGQQFQALNARAATFHAEFVSLLNGGAAAYTGAEAASVSSM Rv1651c|M.tuberculosis_H37Rv AAVSRLFGAYGQQFQALNARAATFHAEFVSLLNGGAAAYTGAEAASVSSM MMAR_3570|M.marinum_M AAIAAVFGEHGQAYQAFSAQATAFHADFVEALTTGVGSYAAAEATNAG-- MUL_1639|M.ulcerans_Agy99 AAISQVFGAYGQEFQALNAQAAAFQAEFEGLLSGGAAAYVSAEALNSSVF MSMEG_5578|M.smegmatis_MC2_155 CARAHIRTAYEGIFMEVAARSR---------LLAGAAIIGAG-------- TH_2715|M.thermoresistible__bu TALANPFEVYGALIEETLANLS---------------------------- Mflv_1343|M.gilvum_PYR-GCK AAVPNPIQLYSQVFQRSLDNAG---------------------------- Mvan_3971|M.vanbaalenii_PYR-1 TAQPNPIALWTEVFAGAINNIG---------------------------- * . . Mb1679c|M.bovis_AF2122/97 ----QALLDAVNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGGPGGILYG Rv1651c|M.tuberculosis_H37Rv ----QALLDAVNAPTQTLLGRPLIGNGADGVAGTGSNAGGNGGPGGILYG MMAR_3570|M.marinum_M ----QALLGAVNAPAQALLGRPLIGN---GIDGTATNP--NGGDGGLLYG MUL_1639|M.ulcerans_Agy99 GPPMQELLKVVNAPTQMLLGRSLIADG----------------------- MSMEG_5578|M.smegmatis_MC2_155 -----ALVAAPIQPVPDVIAAPVIQS------------------------ TH_2715|M.thermoresistible__bu ------VIGERIAANPAPILQQLIAN------------------------ Mflv_1343|M.gilvum_PYR-GCK ------ALAQQYFADPFPITGAILRN------------------------ Mvan_3971|M.vanbaalenii_PYR-1 ------GLGEDLLSDPFPVLNQILRN------------------------ : . : :: . Mb1679c|M.bovis_AF2122/97 NGGNGGAGGPDGGAGGNGGAAGLIGNGGAGGAGG--VGGAGGAGGAGGTG Rv1651c|M.tuberculosis_H37Rv NGGNG-------GAGGNGGAAGLIGNGGAGGAGG--AGGAGGAGGAGGTG MMAR_3570|M.marinum_M NGGNGYSQTDGGLAGGKGGNAGLIGNGGAGGNGGDYLVGGGGAGGAGGNG MUL_1639|M.ulcerans_Agy99 -------------------------------------ANATAAGGDGRPG MSMEG_5578|M.smegmatis_MC2_155 --------------------------------------ATPAVEMTALVN TH_2715|M.thermoresistible__bu ----------------------------------------QLASAEILGN Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 ----------------------------------------QFGYLQTIGE Mb1679c|M.bovis_AF2122/97 GLLYGNGGAGGNGGS---AAAAGGAGGNALLFGNGGNGGSGASGGAAGHA Rv1651c|M.tuberculosis_H37Rv GLLYGNGGAGGNGGS---AAAAGGAGGNALLFGNGGNGGSGASGGAAGHA MMAR_3570|M.marinum_M GVLYGNGGTGGAGGSGTTSYGAAGVGGNALLFGNGGTGGSGLGG------ MUL_1639|M.ulcerans_Agy99 GILMGKGGDGAPGGP--------GQPG----------------------- MSMEG_5578|M.smegmatis_MC2_155 PIELWSAVISQAIAN----------------------------------- TH_2715|M.thermoresistible__bu ALQLAGTQLGEALSP----------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 AGKGIIDGLVEYASP----------------------------------- Mb1679c|M.bovis_AF2122/97 GTIFGNGGNAGAGSGLAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGG Rv1651c|M.tuberculosis_H37Rv GTIFGNGGNAGAGSGLAGADGGLFGNGGDGGSSTSKAGGAGGNALFGNGG MMAR_3570|M.marinum_M -------------------------------------GGNGGNAVFGNGG MUL_1639|M.ulcerans_Agy99 ----------------------------------------------GNGG MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 DGGSSTVAAGGAGGNTLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLWGS Rv1651c|M.tuberculosis_H37Rv DGGSSTVAAGGAGGNTLVGNGGAGGAGGTSGLTGSGVAGGAGGSVGLWGS MMAR_3570|M.marinum_M AGGAGVAGIGGNGGNTFIGTGGAGGAGGGTILGGGSHAGGDGGSVGLWGS MUL_1639|M.ulcerans_Agy99 AAG-------------LIGTGGAGGKGAPSMP------------------ MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GGAGGDGGAATSLLGVGMNAGAGGAGGNAGLLYGNGGAGGAGGNGGDTTV Rv1651c|M.tuberculosis_H37Rv GGAGGDGGAATSLLGVGMNAGAGGAGGNAGLLYGNGGAGGAGGNGGDTTV MMAR_3570|M.marinum_M GGVGGAG--TTPDADSGYAGGDGGNGGNGGLLYGDGGAGGAGGLGSDYSS MUL_1639|M.ulcerans_Agy99 ----------------------GGLGGRGGLLWGDGGKGGDGG------A MSMEG_5578|M.smegmatis_MC2_155 ------------------------TGAIANTVLENPIP---------IAH TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 PLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGAGG Rv1651c|M.tuberculosis_H37Rv PLFDSGVGGAGGAGGNASLFGNGGTGGVGGKGGTSSDLASATSGAGGAGG MMAR_3570|M.marinum_M LFYNAGNGGNGGVGGNASLVGNGGAGGAGGAGGTGSSLSYG--GHGGNGG MUL_1639|M.ulcerans_Agy99 PVYDAWG----------YLLAEAGTGGAGGLPG----------------- MSMEG_5578|M.smegmatis_MC2_155 KVIDNQLITADVLTSFVALFGEGFVASAGGVPA----------------- TH_2715|M.thermoresistible__bu -------------------------DNPRGVPAN---------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------DNPFGLQAG---------------- Mb1679c|M.bovis_AF2122/97 AGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNGGN Rv1651c|M.tuberculosis_H37Rv AGGVGGLLYGNGGNGGAGGIGGAAINILANAGAGGAGGAAGSSFIGNGGN MMAR_3570|M.marinum_M NGGTDGLLFGKGGAGGDGGAGGGTT-SSGTGGSGGTGGTGGSSFIGSGGT MUL_1639|M.ulcerans_Agy99 -------IFG---------------------------------------- MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGSLF Rv1651c|M.tuberculosis_H37Rv GGAGGAGGAAALFSSGVGGAGGSGGTALLLGSGGAGGNGGTGGANSGSLF MMAR_3570|M.marinum_M GGAGGAG----------GTATGSG-------ASGAGGAGGSGGYNG---F MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 ASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIGGT Rv1651c|M.tuberculosis_H37Rv ASPGGTGGAGGHGGAGGLIWGNGGAGGNGGNGGTTADGALEGGTGGIGGT MMAR_3570|M.marinum_M IGAGGTGGAGGDGGGG----NQGAAAGDGGSGGTAAG------------- MUL_1639|M.ulcerans_Agy99 -GLPGVAGAWG--------------------------------------- MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDGGT Rv1651c|M.tuberculosis_H37Rv GGSAIAFGNGGQGGAGGTGGDHSGGNGIGGKGGASGNGGNAGQVFGDGGT MMAR_3570|M.marinum_M -----LFGAGGTGGTGGTGGTTTANGGTGGAAGVGGSGGDASSLIALGGT MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 GGTGGAGGAGSG--TKAGGTGSDGGHGGNAT-LIGNGGDGGAGGAGGAGS Rv1651c|M.tuberculosis_H37Rv GGTGGAGGAGSG--TKAGGTGSDGGHGGNAT-LIGNGGDGGAGGAGGAGS MMAR_3570|M.marinum_M GGVGGVGGAATGGGATIGADGGTGGNGGNATGLLNFGGSGGAGGAGGAGA MUL_1639|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5578|M.smegmatis_MC2_155 -------------------------------------------------- TH_2715|M.thermoresistible__bu -------------------------------------------------- Mflv_1343|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3971|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1679c|M.bovis_AF2122/97 PAGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYED Rv1651c|M.tuberculosis_H37Rv PAGAPGNGGTGGTGGVLFGQSGSSGPPGAAALAFPSLSSSVPILG-PYED MMAR_3570|M.marinum_M TTGVQGAGGMGGTP------GGQPGAAAVSALLPGGLASSTAAVGGAYQD MUL_1639|M.ulcerans_Agy99 ---------------------GEVPTALAAPMALSAAASSPAAVGGAYQT MSMEG_5578|M.smegmatis_MC2_155 ----------------------ALQSAVEQILAGEIYSGVENYAIAILTP TH_2715|M.thermoresistible__bu -----------------------LRVALDHLMAGNIEGAIIGLWQATITP Mflv_1343|M.gilvum_PYR-GCK -----------------------QGVAVADALAALQAGDSEAFVAAATDV Mvan_3971|M.vanbaalenii_PYR-1 -----------------------IRDAVAQFKAGDIGAAFTTLASTVITG . . Mb1679c|M.bovis_AF2122/97 LIANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFA Rv1651c|M.tuberculosis_H37Rv LIANTVANLASIGNTWLADPAPFLQQYLANQFGYGQLTLTALTDATRDFA MMAR_3570|M.marinum_M LFTNTITNLQSLGATWAANPAPFLGQIVSNQFGYGQLIFAALGNATRDFT MUL_1639|M.ulcerans_Agy99 LFDNTWTNLQAIGATWNADPAPFLSQFIANQQTYANTVFTSLSNSVQDFG MSMEG_5578|M.smegmatis_MC2_155 VVEGALGALGQLDDISAVLQNPFLNAANVVGTVVSVPTLIGAGLPILFEA TH_2715|M.thermoresistible__bu LVG---PATLLIPAVHQVIRQPVQNLLNVVDAVQAPIMLLAVG-ALNPVY Mflv_1343|M.gilvum_PYR-GCK VLEPFRGTGAALSHLGALLNQPYAVEGFFLIAIS-------------PVL Mvan_3971|M.vanbaalenii_PYR-1 PIIVGAGLPLLMSGLLEVPVKMAQNFTDAVAALLNPTTAVPLITAALGPI . : Mb1679c|M.bovis_AF2122/97 IG-LAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNI Rv1651c|M.tuberculosis_H37Rv IG-LAGIPPSLQSALQALAAGDVSGAVTDVLGAVVKVFVSGVDASDLSNI MMAR_3570|M.marinum_M LG-LAGLPPTFQTAFQAVLAGDFSGAASDMAEGLSKLVATGVDTSDLSNI MUL_1639|M.ulcerans_Agy99 AG-LVALPAAYQGAFQALMTGNVSGAVEILGKGYLGLVFNGFDYTNVPVV MSMEG_5578|M.smegmatis_MC2_155 LSPILQVGLTAQGVYDGVTAGDLEAVANALISFPSDMAGTILNGN--PTI TH_2715|M.thermoresistible__bu TGLVKGGGTFAQDVFDAVTSGDLEGLANAFITGPAGMIGGLLNGDGIDSG Mflv_1343|M.gilvum_PYR-GCK AG-VAATQRAFEEVIDALVGFDLVGAAYAVLNIPGRVIDGVLNGVP---- Mvan_3971|M.vanbaalenii_PYR-1 LGPFSALGASVQDFVEALGSGDVLDAITTVINVPAKLVGAALNGFTDEG- . . : :.: :. . : .: Mb1679c|M.bovis_AF2122/97 LLL-GPVGDLFP--ILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGV Rv1651c|M.tuberculosis_H37Rv LLL-GPVGDLFP--ILSIPGAMSQNFTNVVMTVTDTTIAFSIDTTNLTGV MMAR_3570|M.marinum_M KLL-GPVGDLLP--ILRIPGDTAFNVANVIRTPTDTTVSVEFTSYVPPAI MUL_1639|M.ulcerans_Agy99 TVQ-GALGDLLP--MTTIPGQISQNMTNVLQTVTDTSIMANISLLNPSFT MSMEG_5578|M.smegmatis_MC2_155 GNS-GLLGSELG--LIPSLLTVRQSIADAIQPPAVSTLVGAKMESAPEVN TH_2715|M.thermoresistible__bu LLTPNVLGTINQ--LLGLRDAIAGALGATLTVGTAADEISSAAIDTGDTV Mflv_1343|M.gilvum_PYR-GCK -------GASFG--ILEDLPGLLSPLSETGLPPGPIAVGTSLDQDMGAAI Mvan_3971|M.vanbaalenii_PYR-1 -------GNFFAGILTVSDDPFSAGLLQTLLVTVPRAVAAALGAEDAPAR * : . . Mb1679c|M.bovis_AF2122/97 M-TFGLPLAMTLNAVG-SPITTAIAFAESTTAFVSAVQAGNLQAAAAALV Rv1651c|M.tuberculosis_H37Rv M-TFGLPLAMTLNAVG-SPITTAIAFAESTTAFVSAVQAGNLQAAAAALV MMAR_3570|M.marinum_M TGTFGLPVALTLDAAG-SAVTTANAVGTSVTALTNAVQAGDWPAAIGALV MUL_1639|M.ulcerans_Agy99 T---GFPLTLALDALG-APIVTGQAALQSATTFIDAVQAGDVAGAFGAIV MSMEG_5578|M.smegmatis_MC2_155 SFTFTVDEDGELGEVTKSTTESGTTEGNGIQAIAAKSADAEDDATTGTGT TH_2715|M.thermoresistible__bu TLDVTVPTAG-VSKVGAVAGQSEDSVTEEGVAGSELTAADDADGTVTTKG Mflv_1343|M.gilvum_PYR-GCK P---------------PREPATGVGDVPDLAAATITLDADEVPAEDSGRS Mvan_3971|M.vanbaalenii_PYR-1 V----------------AGALDEVSSPISEPAAAVTVSVTETDSATTEVD : : . Mb1679c|M.bovis_AF2122/97 GAPANVANGFLNGEARLPLALP---TSATGGIPVTVEVPVGGILAPLQPF Rv1651c|M.tuberculosis_H37Rv GAPANVANGFLNGEARLPLALP---TSATGGIPVTVEVPVGGILAPLQPF MMAR_3570|M.marinum_M DAPAVVANGFLNGQGTMTVPLS---VPIVD--SAVINFPVNGILVPPHDY MUL_1639|M.ulcerans_Agy99 DAPAVIANGFLNGEETITLDLPTYLSPISGTESLTSAIPIGGILTPLQPV MSMEG_5578|M.smegmatis_MC2_155 ETEPEKSEKPVEKSKKPLVTLGNKFSPTTTAGDKARPGQRAEAALKSIGN TH_2715|M.thermoresistible__bu ALSTVVEDDGTRTRSSLKAVPGEAATGVSKTGERPAPARGVRGQHRDAAT Mflv_1343|M.gilvum_PYR-GCK DADDAPAEDTTETEGTDEESGDSADAESSEGGAEPAEGGAEGAEAESG-- Mvan_3971|M.vanbaalenii_PYR-1 SATEVPAAEPEETPTAPAEEAPVEEAPAEERADTSAEDGAVQGDAEVTDG . Mb1679c|M.bovis_AF2122/97 QATAVIPVIGP-----VTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--- Rv1651c|M.tuberculosis_H37Rv QATAVIPVIGP-----VTVTLEGTPAGGIVPALVNYAPTQLAQAIAP--- MMAR_3570|M.marinum_M TATVVIAGFS------YDVPIMGTPIGGIVPGLLTYAPQQFANAIGAAG- MUL_1639|M.ulcerans_Agy99 ESTIVFRVLPHTPPVTQHITLGGTEFGGLIPGLQS-ASAQLADAIKLS-- MSMEG_5578|M.smegmatis_MC2_155 EVNKTVKKIGDG-----VKKALGVKGKKKADSKASSSSKDSAGSED---- TH_2715|M.thermoresistible__bu SVHNGVRGVVG------AKRATTTGSDASASSTGSSRSGTDSGSDDK--- Mflv_1343|M.gilvum_PYR-GCK -------------------QAAPARTSAKPDSTRSDRTRADAGTSDTE-- Mvan_3971|M.vanbaalenii_PYR-1 EPVVDEAADGDD---APTSDDTEADDAGADEGTPSDTSAGDADSTDSSAA . . . . : :