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RAGVRSCLTASVALVGAGAIAITPVNPLTTDVLPITQHAVSLAAVPNPIQLYSQVFQRSLDNAGALAQQY FADPFPITGAILRNQGVAVADALAALQAGDSEAFVAAATDVVLEPFRGTGAALSHLGALLNQPYAVEGFF LIAISPVLAGVAATQRAFEEVIDALVGFDLVGAAYAVLNIPGRVIDGVLNGVPGASFGILEDLPGLLSPL SETGLPPGPIAVGTSLDQDMGAAIPPREPATGVGDVPDLAAATITLDADEVPAEDSGRSDADDAPAEDTT ETEGTDEESGDSADAESSEGGAEPAEGGAEGAEAESGQAAPARTSAKPDSTRSDRTRADAGTSDTE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1343 | - | - | 100% (347) | hypothetical protein Mflv_1343 |
| M. gilvum PYR-GCK | Mflv_2285 | - | 2e-19 | 26.47% (374) | hypothetical protein Mflv_2285 |
| M. gilvum PYR-GCK | Mflv_1753 | - | 6e-13 | 27.32% (377) | hypothetical protein Mflv_1753 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3842 | PE_PGRS62 | 5e-05 | 27.23% (191) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3812 | PE_PGRS62 | 5e-05 | 27.23% (191) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5322 | - | 2e-20 | 30.20% (394) | hypothetical protein MSMEG_5322 |
| M. thermoresistible (build 8) | TH_3688 | - | 3e-21 | 25.77% (392) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0052 | - | 7e-60 | 38.46% (377) | hypothetical protein Mvan_0052 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1343|M.gilvum_PYR-GCK ----------MRAGVRSCLTASVALVGAGAIAITPVNPLTTDVLP-----
Mvan_0052|M.vanbaalenii_PYR-1 ----------MIATMKPAFTAGVALLGAGVIACAPVEP-AAAVAP-----
Mb3842|M.bovis_AF2122/97 MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIA
Rv3812|M.tuberculosis_H37Rv MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIA
TH_3688|M.thermoresistible__bu ----------MLSSIRPYATAGVALVGAGVIAVAPTVTPPLPDIK-----
MSMEG_5322|M.smegmatis_MC2_155 ----------MQQAVRSYLTAGVAFAGAGVIAVSPVAPLPPDITER----
: : . :: * . * *. .
Mflv_1343|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0052|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3842|M.bovis_AF2122/97 VSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANGGQLFG
Rv3812|M.tuberculosis_H37Rv VSQLFGRYGQEFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANGGQLFG
TH_3688|M.thermoresistible__bu --------------------------------------------------
MSMEG_5322|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1343|M.gilvum_PYR-GCK ---ITQHAVSLAAVPNPIQLYSQVFQRSLDNAGALAQQYFADPFPITGAI
Mvan_0052|M.vanbaalenii_PYR-1 ---VVDATVQLSAIPSPLELYPQVLVRAVQNSAALVEAYLADPLPLTRLT
Mb3842|M.bovis_AF2122/97 QIEAGQRAVSAAAAAAPGGAYGQLVANTATNLESLYGAWSANPFPFLRQI
Rv3812|M.tuberculosis_H37Rv QIEAGQRAVSAAAAAAPGGAYGQLVANTATNLESLYGAWSANPFPFLRQI
TH_3688|M.thermoresistible__bu --VPATVASPVQLTVSPIEFYTGLFERTTGNASALVEKFLANPAPILSQI
MSMEG_5322|M.smegmatis_MC2_155 --AQSSAGVALSALANPIDGYAAAFTAALKNAEALTARIAAAPAPILSNI
* * . : * :* * * *:
Mflv_1343|M.gilvum_PYR-GCK LRNQG-----------VAVADALAALQAGDS-----EAFVAAATDVVLEP
Mvan_0052|M.vanbaalenii_PYR-1 IEKQI-----------VALGEAFDALGEGDG-----AAAMAAIGRVILQP
Mb3842|M.bovis_AF2122/97 IANQQ-----------VYWQQIAAALANAVQNFPALVANLPAAIDAAVQQ
Rv3812|M.tuberculosis_H37Rv IANQQ-----------VYWQQIAAALANAVQNFPALVANLPAAIDAAVQQ
TH_3688|M.thermoresistible__bu IENQV-----------ANLEFAMEVIPTSINDAIEVFNTVGRAQLEIAFQ
MSMEG_5322|M.smegmatis_MC2_155 VRNQVNSAAGVATFAEVFTSSVITALADTPEQLQSAVEKFSAGDVTGALE
: :* . .: .
Mflv_1343|M.gilvum_PYR-GCK FRGTGAALSHLGALLNQPYAVEGFFLIAISPVLAGVAATQRAFEEVIDAL
Mvan_0052|M.vanbaalenii_PYR-1 VRTVFGAFEYVDILMNQPNAPQALFQIALSPILGGVAAFGVAIDEVVDAA
Mb3842|M.bovis_AF2122/97 FLAFNAAY-YIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLA
Rv3812|M.tuberculosis_H37Rv FLAFNAAY-YIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLA
TH_3688|M.thermoresistible__bu QLAEGDLYGAVQTVQNIMLPVALPLLEALGAPLRPIMMASDNLNRVVQQV
MSMEG_5322|M.smegmatis_MC2_155 TVLQTVLGPVVNGVVDTLLFNPDVWAGLQNAIRQPVANTLSVIDLLAEPE
: : . . : : :
Mflv_1343|M.gilvum_PYR-GCK VG-------FDLVGAAYAVLNIPGRVIDGVLNGVPGASFGILEDL-----
Mvan_0052|M.vanbaalenii_PYR-1 AA-------LDLVGLVNAVVNIPARVLDGVLNGGYGSPFGDFDNL-----
Mb3842|M.bovis_AF2122/97 FQ-------QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTIS
Rv3812|M.tuberculosis_H37Rv FQ-------QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTIS
TH_3688|M.thermoresistible__bu IPSLILAGPIALIGPINATMAAAVYVVQSIADGVMSGDPIEVVNALINAP
MSMEG_5322|M.smegmatis_MC2_155 VYN-VLGPLLAPVQLLTDLTDAVGAAGDDVFAGIKTGDLEKVANAVINLG
: . .: .
Mflv_1343|M.gilvum_PYR-GCK ----PGLLSP----------LSETG-LPPGPIAVGTSLDQDMGAAIPPRE
Mvan_0052|M.vanbaalenii_PYR-1 ----PGLVTP----------LTVEGYLFPGPIALGILIDQDAADYIEDQA
Mb3842|M.bovis_AF2122/97 VTAKPKLLGP----------LGDLFTIMTIPAQEAQYFTNLMPPSILRDM
Rv3812|M.tuberculosis_H37Rv VTAKPKLLGP----------LGDLFTIMTIPAQEAQYFTNLMPPSILRDM
TH_3688|M.thermoresistible__bu GVVIDGFLNGGYGGVLNGGILSVAGMGPPGPIDLLLTFREQIAQALVPQG
MSMEG_5322|M.smegmatis_MC2_155 PNFTYALLNGAPGMPG----FSAGLLGPQGVVAGLLTLRDMVADAIAPAT
:: : : : :
Mflv_1343|M.gilvum_PYR-GCK --------------PATGVG--DVPDLAAATITLDADEVPAEDSGRSDAD
Mvan_0052|M.vanbaalenii_PYR-1 GQQELTELTATDAPEPEAVD--ESAGPAEDEVAGIFDELETDDPQTADPA
Mb3842|M.bovis_AF2122/97 SQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPLVLTYATLGAPF
Rv3812|M.tuberculosis_H37Rv SQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPLVLTYATLGAPF
TH_3688|M.thermoresistible__bu PYAPTTSAASAVEESAPPTAQVTKTTLGNNVVDVEVSATSLDTTTSSAAG
MSMEG_5322|M.smegmatis_MC2_155 TAAKTAAGTAAVAEPAALTRASVTLDVPKALVGPETPAAGAVTTPAEATT
. . .
Mflv_1343|M.gilvum_PYR-GCK DAPAEDTTETEGTD----------EESGDSADAESSEGGAEPAEGGAEGA
Mvan_0052|M.vanbaalenii_PYR-1 AAPTEPADTIDGEEGGESADTIDGEEGGESADTIDGEDGGEPADT-IDGE
Mb3842|M.bovis_AF2122/97 ASLNAIATSAETIEQALLAGNYLGAVGALIDAPAHALDGFLNSATVLDTP
Rv3812|M.tuberculosis_H37Rv ASLNAIATSAETIEQALLAGNYLGAVGALIDAPAHALDGFLNSATVLDTP
TH_3688|M.thermoresistible__bu PEGNSTPVAKTGNDGAGSENPVEQVESEGLSDTGLSDDDSTTALKNDEST
MSMEG_5322|M.smegmatis_MC2_155 DAPAAATDTSTKQAPSATDAASASAASEAKPVADDSEEAITTPAKPSTVA
. . . . .
Mflv_1343|M.gilvum_PYR-GCK EAESGQAAPART----------------SAKPDSTRSDRTRADAGTSDTE
Mvan_0052|M.vanbaalenii_PYR-1 DGGEPETDDGQD----------------GGEPETDDGQGTGESAGTENSD
Mb3842|M.bovis_AF2122/97 ILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFP
Rv3812|M.tuberculosis_H37Rv ILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFP
TH_3688|M.thermoresistible__bu TPSGGTDLSNGNKVSPTATTAATTQNGVAKNRGLTKASLGDATGGSSGGD
MSMEG_5322|M.smegmatis_MC2_155 KPKKVNAVKDIRN-------------GIRGAIKNVRNGVKDAVAGLSGKK
.
Mflv_1343|M.gilvum_PYR-GCK ---------------------------------
Mvan_0052|M.vanbaalenii_PYR-1 PATE-----------------------------
Mb3842|M.bovis_AF2122/97 TTVTVFGTPFMGMAPLLINYIPQQLALAIKPAA
Rv3812|M.tuberculosis_H37Rv TTVTVFGTPFMGMAPLLINYIPQQLALAIKPAA
TH_3688|M.thermoresistible__bu SGSATGSSRTTAGSGNTGGSDSGDE--------
MSMEG_5322|M.smegmatis_MC2_155 AKPAKPVKQESSTKSGGSESDGGGSGGGAE---