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MKFLFDDESFSFETLRAAGYANYGGADLGDVLVTARAIPEGDEQAWFREWKATAERVEALGRRSQAAGHT VSAREALLRASNYYRTAEFYRRENPWEDAEALETFNRSRTTFLDAMALFDFGFERVAIPYEDTTLPGYLY LVDDRPRPTVIFNGGYDSTLEESYVALAAAALARGYHVLAFDGPGQGAALREQRLTFRHDWEAVLTPVVD FALTRSEIAPDAITVFGYSMGGFLVARAAAFEDRFAAVVVDDGIYDFHSAMAKVMPPFLAEWVEQGNDDD ANAVFRLMMSTGTGLRWIMQNGMWNFGLDSPAALARAFRAYTLDGIADRITAPVLVLDAENDQFFDHEPE RAAAAMVNAKTTLVTLYEADGAGEHCHLGAVHRAHQVVFDWLDEIVGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5341 | - | - | 100% (398) | dipeptidyl aminopeptidase/acylaminoacyl peptidase |
| M. smegmatis MC2 155 | MSMEG_4066 | - | 6e-46 | 30.73% (384) | hypothetical protein MSMEG_4066 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3465 | - | 9e-08 | 25.00% (252) | peptidase S15 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3564c | - | 2e-95 | 46.17% (405) | dipeptidyl aminopeptidase/ acylaminoacyl-peptidase related |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2570 | - | 9e-10 | 29.57% (230) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1006 | - | 1e-07 | 23.84% (281) | protein of unknown function DUF1100, hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5341|M.smegmatis_MC2_155 ------MKFLFD-DESFSFETLRAAG---------------YANYGGADL
MAB_3564c|M.abscessus_ATCC_199 ------MRFIFETDESFSFETLRTVG---------------YTAYGGADI
Mflv_3465|M.gilvum_PYR-GCK ---------------MTAGWTTSAVS---------------FPCDGEQIA
TH_2570|M.thermoresistible__bu ----------------MATTDRRDLR---------------IPAHGEQLA
Mvan_1006|M.vanbaalenii_PYR-1 MAGHAVARRLVTSGCALTRTTEWAASRWGTAYFLPALFADRVTHLGGIDK
: . *
MSMEG_5341|M.smegmatis_MC2_155 GDVLVTARAIPEGDEQAWFREWKATAER-VEALGRRSQAAG------HTV
MAB_3564c|M.abscessus_ATCC_199 GEVVTTAKRITPGDWESWYIEWRALADR-IAAIAAKCAAAG------HAV
Mflv_3465|M.gilvum_PYR-GCK GVLYRPEGGAPPFPCVVFAHGFSGTMDWILPDFAAVFCAAG------LAV
TH_2570|M.thermoresistible__bu AYFYPPAGAGPTTPCIVMAHGFTATRDDGLPAYAEAFHAAG------YAV
Mvan_1006|M.vanbaalenii_PYR-1 RFFAEQLAQCRSFRDGSWAGHWQAIAADHAGVADAALARLGGPTVAQMLA
. : . * .
MSMEG_5341|M.smegmatis_MC2_155 SAREALLRASNYYRTAEFYRRENPWEDAEALETFNRSRTTFLDAMALFDF
MAB_3564c|M.abscessus_ATCC_199 SASTAYLRASNYYRTAEFFLRDDPGNDPRVLDTSARAVETFRSAPEIQAR
Mflv_3465|M.gilvum_PYR-GCK LTFDYRGFGSSEGTPRQIVNSARQLEDIRAALDVVRNRADVDPG------
TH_2570|M.thermoresistible__bu VLFDYRHFGASTGEPRQLLDITRQHDDYRAVVAWARTQPGVDPD------
Mvan_1006|M.vanbaalenii_PYR-1 GPVDTSALGELLTPAVSILADRGPVASPDAVTTFRLHSGGAGDDAAIAVD
. . .: . .
MSMEG_5341|M.smegmatis_MC2_155 GFERVAIPYEDTTLPG-YLYLVDDRPRP-------TVIFNGGYDSTLEES
MAB_3564c|M.abscessus_ATCC_199 -WERVQIPYEGIQLEGYYLNASGDDRGP-------TLLAHGGFDSTVEEM
Mflv_3465|M.gilvum_PYR-GCK -----RIGLWGTSLGGSHVLQIAAE--------------DPRVAAVVANV
TH_2570|M.thermoresistible__bu -----RIVLWGSSFSGGHVLVVAAD--------------DPRIAAVISQA
Mvan_1006|M.vanbaalenii_PYR-1 ALIKVVTYKFAAAWPGWTPQRLKAHAQSRRLCDVLTEALAPAMGLSIEHL
* : .
MSMEG_5341|M.smegmatis_MC2_155 YVALAAAALARGYHVLAFDGPGQGAALREQ--------------------
MAB_3564c|M.abscessus_ATCC_199 YFAVGEAARRYGWNCLIFEGPGQGAALRAD--------------------
Mflv_3465|M.gilvum_PYR-GCK PALDMYTGLRGRHRSPDYRPGPAQIVVAVA--------------------
TH_2570|M.thermoresistible__bu PFTDAVPTLR---KVP---P------ATIA--------------------
Mvan_1006|M.vanbaalenii_PYR-1 RVPVPGGDVVEGAAVFPLGVRGSPTVLCAKGLEGVVAETLLPWLKFRGHG
MSMEG_5341|M.smegmatis_MC2_155 --------------RLTFRHDWEAVLTPVVDFALTRSEIAPDAITVFGYS
MAB_3564c|M.abscessus_ATCC_199 --------------KVTFRYDWEAVVTPVLDFALGLPGVDPDRVALLGMS
Mflv_3465|M.gilvum_PYR-GCK --------------RLLS--------AAVVDEVRGRLGRSPRYLPVYG-R
TH_2570|M.thermoresistible__bu --------------RLAV--------AGLRDQIGSWRGRPPRTASAVG-A
Mvan_1006|M.vanbaalenii_PYR-1 LGMFIMEMPGTYTYRQPLTVAAENVYRAVIDRLAADPRVDADRIGMLGLS
: : * . *
MSMEG_5341|M.smegmatis_MC2_155 MGGFLVARAAAFEDRFAAVVVDDGIYDFHSAMAKVMPPFLAEWVEQGNDD
MAB_3564c|M.abscessus_ATCC_199 MGGYLAPRAAAFEPRLAACVAYDSVFKLSAGMPKTHDDEHKLDSAQRVAA
Mflv_3465|M.gilvum_PYR-GCK LG-RAFFADPALAQRFRAVEAQAPSWRN----------------------
TH_2570|M.thermoresistible__bu PGAVAAMTTPDAEPGFRAIVEPDSLWRN----------------------
Mvan_1006|M.vanbaalenii_PYR-1 FGAYWAARMAAADPRLRAVVANGAPADRTFRPSGAFG-------------
* . : *
MSMEG_5341|M.smegmatis_MC2_155 DANAVFRLMMSTGTGLRWIMQNGMWNFGLDSPAALARAFRAYTLDGIADR
MAB_3564c|M.abscessus_ATCC_199 VGNLIAHRAEAP-SSQRWVLSNALWVFGVDSAQSLLDEVEKYDLSDVAHQ
Mflv_3465|M.gilvum_PYR-GCK -----------------------------AVAPRFLLHAPRYRDGTIE-R
TH_2570|M.thermoresistible__bu -----------------------------EFAARLMLRFPFYRPVRVAGR
Mvan_1006|M.vanbaalenii_PYR-1 --------------TPEIMMWTMANTTHARSTADLLTKLRALSLKDLYPR
. : : :
MSMEG_5341|M.smegmatis_MC2_155 ITAPVLVLDAENDQFFDHEPERAAAAMVNAKTTLVTLYEADGAGEHCHLG
MAB_3564c|M.abscessus_ATCC_199 ISCPTLVCEAENDQFFHGQPSMLYDALQCPKTYLK-FTEAEGAGEHCHEG
Mflv_3465|M.gilvum_PYR-GCK VRCPVLVTLARDDAEVS-TPFVERKVRRGRDVEIR--KYPAGHFDMYHGA
TH_2570|M.thermoresistible__bu INAPLLVCVCDDDAVTP-PEPAIEAARRAPRGQLR--RYPYGHFDIYH--
Mvan_1006|M.vanbaalenii_PYR-1 MTAPLLVINGDSDTLAS-TRDSIDIATYAPNALLK----LYPGDDHCAMG
: .* ** .* . : :
MSMEG_5341|M.smegmatis_MC2_155 AVHRAHQVVFDWLDEIVGG--------
MAB_3564c|M.abscessus_ATCC_199 ALLLFHQRMFDWLDDAVGA--------
Mflv_3465|M.gilvum_PYR-GCK VRDEVARDQREFLIRHLQPDRAARKDR
TH_2570|M.thermoresistible__bu -DPQVKSDQLDFLRQVLGTG-------
Mvan_1006|M.vanbaalenii_PYR-1 HARQWWDLAVRFLADQLGAV-------
:* :