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EIDFRDDRIGGFNYEFFRTISSPVAEMGETLGVAYRIKDGDIESWLTNFSDAAKRIHERAVAYAENGIAA SASRAFMRASNFYRSSIFYAVESDPRREEYWRISRDCFRRAMELRSAPVRTVGIPFGGAVLPGYFFSAGA ENRPTLIAIGGFDSTAEEVVAWIGLEAQNHGWNCLVFEGPGQWGALYDNPGLTMYPDYERPVSAAVDFAC SFSEVDPERVALVGFSLGGYLAPRAFAFDSRIKACIANSFLPSVLEPWTGLWPPSLAGLRGDAFDAAFAE ASETNPGAAWTFDHGQWALGFDRPSGFLDIWRDYTLFDHVERFDRPFLSIFGESELAKFEHGSGIGKWAN RMLDFFADTPSYCETYVFTDEEGGSTHCQMGGISQGAAVTMSWLENVLGDGAARAEQNISEGNKIMHPEL GRIMRSTFGDEIEDGLKRLAVKPSGRPMAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4066 | - | - | 100% (451) | hypothetical protein MSMEG_4066 |
| M. smegmatis MC2 155 | MSMEG_5341 | - | 7e-46 | 30.73% (384) | dipeptidyl aminopeptidase/acylaminoacyl peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4372 | - | 2e-05 | 29.20% (137) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3564c | - | 4e-54 | 35.93% (398) | dipeptidyl aminopeptidase/ acylaminoacyl-peptidase related |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1006 | - | 4e-09 | 26.33% (281) | protein of unknown function DUF1100, hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4066|M.smegmatis_MC2_155 -------MEIDFRDDRIGGFNYEFFRTISS---PVAEMGETLGVAYRIKD
MAB_3564c|M.abscessus_ATCC_199 -------MRFIFETDES--FSFETLRTVGYTAYGGADIGEVVTTAKRITP
Mflv_4372|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1006|M.vanbaalenii_PYR-1 MAGHAVARRLVTSGCALTRTTEWAASRWGTAYFLPALFADRVTHLGGIDK
MSMEG_4066|M.smegmatis_MC2_155 GDIESWLTNFSDAAKRIHERAVAYAENGIAASASRAFMRASNFYRSSIFY
MAB_3564c|M.abscessus_ATCC_199 GDWESWYIEWRALADRIAAIAAKCAAAGHAVSASTAYLRASNYYRTAEFF
Mflv_4372|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1006|M.vanbaalenii_PYR-1 RFFAEQLAQCRSFRDGSWAGHWQAIAADHAGVADAALARLG---GPTVAQ
MSMEG_4066|M.smegmatis_MC2_155 AVE---SDPRREEYWRISRDCFR-RAMELRSAPVRTVGIPFGGA------
MAB_3564c|M.abscessus_ATCC_199 LRDDPGNDPRVLDTSARAVETFR-SAPEIQARWER-VQIPYEGI------
Mflv_4372|M.gilvum_PYR-GCK -------------------------------MSRTEVAFPSGGD------
Mvan_1006|M.vanbaalenii_PYR-1 MLAGPVDTSALGELLTPAVSILADRGPVASPDAVTTFRLHSGGAGDDAAI
. : *
MSMEG_4066|M.smegmatis_MC2_155 ------VLPGYFFSAGAENR-PTLIAIGGFDSTAEEVVAWIGLEAQNHGW
MAB_3564c|M.abscessus_ATCC_199 ------QLEGYYLNASGDDRGPTLLAHGGFDSTVEEMYFAVGEAARRYGW
Mflv_4372|M.gilvum_PYR-GCK ------TCSAWHFAADGVRR-PVVVMAHGFGGTKDSGLEPFALRFAEAGF
Mvan_1006|M.vanbaalenii_PYR-1 AVDALIKVVTYKFAAAWPGWTPQRLKAHAQSRRLCDVLTEALAPAMGLSI
: : * * : . . . .
MSMEG_4066|M.smegmatis_MC2_155 NCLVFEGPGQWGALYDNPGLTMYPDYERPVSAAVDFACSFSEVDPERVAL
MAB_3564c|M.abscessus_ATCC_199 NCLIFEGPGQGAALRADK-VTFRYDWEAVVTPVLDFALGLPGVDPDRVAL
Mflv_4372|M.gilvum_PYR-GCK DVFAFDYRGFGASEGTPRQSLSVRRQIDDYHAAIHAARQLDGVDPDRVAL
Mvan_1006|M.vanbaalenii_PYR-1 EHLRVPVPG-GDVVEGAAVFPLGVRGSPTVLCAKGLEGVVAETLLPWLKF
: : . * . . . : :
MSMEG_4066|M.smegmatis_MC2_155 VGFSLGGYLAPRAFAFDSRIKACIANS--FLPSVL-EPWTGLWPPSLAGL
MAB_3564c|M.abscessus_ATCC_199 LGMSMGGYLAPRAAAFEPRLAACVAYDSVFKLSAG-MPKTHDDEHKLDSA
Mflv_4372|M.gilvum_PYR-GCK WGASFSGGHVVRVAAERADVAAVIALT---PLTSG-VAVSRSAMASRDTV
Mvan_1006|M.vanbaalenii_PYR-1 RGHGLGMFIMEMPGTYTYRQPLTVAAENVYRAVIDRLAADPRVDADRIGM
* .:. : :* . .
MSMEG_4066|M.smegmatis_MC2_155 R-GDAFDAAFAEASETNPGAAWTFDHGQWALGFDRPSGFLDIWRDYTLFD
MAB_3564c|M.abscessus_ATCC_199 QRVAAVGNLIAHRAEAPSSQRWVLSNALWVFGVDSAQSLLDEVEKYDLSD
Mflv_4372|M.gilvum_PYR-GCK TSLKWTLTGLKSRIAVGRGGSPTLMPLVSPVGQPGALALEGAYESYTALA
Mvan_1006|M.vanbaalenii_PYR-1 LGLSFGAYWAARMAAADPRLRAVVANGAPADRTFRPSGAFGTPEIMMWTM
. .. . . . .
MSMEG_4066|M.smegmatis_MC2_155 HVERFDRPFLSIFGESELAKFEHGSGIGKWANRMLDFFADTPSYCET--Y
MAB_3564c|M.abscessus_ATCC_199 VAHQISCP--TLVCEAENDQFFHGQ-----PSMLYDALQCPKTYLK----
Mflv_4372|M.gilvum_PYR-GCK GPTWRNEIDSSIGLQVVGVRTTAAAKKLRCPLLVQIADFDQYVPADA--V
Mvan_1006|M.vanbaalenii_PYR-1 ANTTHARSTADLLTKLRALSLKDLYPRMTAPLLVINGDSDTLASTRDSID
: : . :
MSMEG_4066|M.smegmatis_MC2_155 VFTDEEGGSTHCQMGGISQGAAVTMSWLENVLGDGAARAEQNISEGNKIM
MAB_3564c|M.abscessus_ATCC_199 -FTEAEGAGEHCHEGALLLFHQRMFDWLDDAVGA----------------
Mflv_4372|M.gilvum_PYR-GCK AKTAAHGRAQVHHYACDHFDVWPGNDWFDKTVTDQIAFLRRTLTRQ----
Mvan_1006|M.vanbaalenii_PYR-1 IATYAPNALLKLYPGDDHCAMGHARQWWDLAVRFLADQLGAV--------
* . . .* : .:
MSMEG_4066|M.smegmatis_MC2_155 HPELGRIMRSTFGDEIEDGLKRLAVKPSGRPMAI
MAB_3564c|M.abscessus_ATCC_199 ----------------------------------
Mflv_4372|M.gilvum_PYR-GCK ----------------------------------
Mvan_1006|M.vanbaalenii_PYR-1 ----------------------------------