For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_5061 (-)

annotation: extracellular solute-binding protein
coordinates: 5161862 - 5163259
length: 465

RARRLCAAAVAAMAAASMVSACGSQTGGIVINYYTPANEEATFKAVANRCNEQLGGRFQIAQRNLPKGAD
DQRLQLARRLTGNDKSLDVMALDVVWTAEFAEAGWAVPLSEDPAGLAEADATENTLPGPLETARWQDELY
AAPITTNTQLLWYRADLMPAPPTTWDGMLDEANRLYREGGPSWIAVQGKQYEGMVVWFNTLLQSAGGQVL
SDDGQRVTLTDTPEHRAATVKALRIIKSVATAPGADPSITQTDENTARLALEQGKAALEVNWPYVLPSLL
ENAVKGGVSFLPLDGDPALQGSINDVGTFSPTDEQFDIAFDASKKVFGFAPYPGVNPDEPARVTLGGLNL
AVASTSQHKAEAFEAIRCLRNVENQRYTSIEGGLPAVRTSLYDDPAFQKKYPQYEIIRQQLTNAAVRPAT
PVYQAVSTRMSATLAPISDIDPERTADELTEAVQKAIDGKGLIP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5061--100% (465)extracellular solute-binding protein
M. smegmatis MC2 155MSMEG_3111-4e-0823.09% (485) extracellular solute-binding protein, family protein 1
M. smegmatis MC2 155MSMEG_5574-2e-0724.75% (295) substrate binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1267lpqY0.069.83% (464) sugar-binding lipoprotein LpqY
M. gilvum PYR-GCKMflv_3851-5e-5831.81% (459) extracellular solute-binding protein
M. tuberculosis H37RvRv1235lpqY0.069.83% (464) sugar-binding lipoprotein LpqY
M. leprae Br4923MLBr_01086-0.071.34% (464) putative solute-binding transport lipoprotein
M. abscessus ATCC 19977MAB_1372-1e-17765.22% (460) sugar ABC transporter, sugar-binding protein LpqY
M. marinum MMMAR_4206lpqY0.070.46% (457) sugar-binding lipoprotein LpqY
M. avium 104MAV_1374-0.069.18% (464) extracellular solute-binding protein
M. thermoresistible (build 8)TH_2061lpqY0.085.75% (449) PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2544-2e-6132.03% (459) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5061|M.smegmatis_MC2_155      ------------------------------------MRARRLCAAAVAAM
TH_2061|M.thermoresistible__bu      --------------------------------------------------
Mb1267|M.bovis_AF2122/97            --------------------------MVMS-----RGRIPRLGAAVLVAL
Rv1235|M.tuberculosis_H37Rv         --------------------------MVMS-----RGRIPRLGAAVLVAL
MAV_1374|M.avium_104                --------------------------MVIG-----RGRVRRAGAVALATL
MMAR_4206|M.marinum_M               --------------------------MRAGQPRSHRGRVWPPGTAVLAAL
MLBr_01086|M.leprae_Br4923          --------------------------MVSR-------RVHRAGTIILAAL
MAB_1372|M.abscessus_ATCC_1997      --------------------------MLESSARWFRRKGVALGSSLLTCL
Mflv_3851|M.gilvum_PYR-GCK          ----------------------------MKRNQFARGRRRRAVALASAPL
Mvan_2544|M.vanbaalenii_PYR-1       MRCDTLSHVPNVLPVALIGDHNFIDEDVMKRNQFARGRRRRAIALATAPL
                                                                                      

MSMEG_5061|M.smegmatis_MC2_155      AAASMVS---ACGSQTGGIVINYYTPANEEATFKAVANRCNEQLGGRFQI
TH_2061|M.thermoresistible__bu      MTASTVA---ACGSDSGEIVISYYTPANEAATFTAVAQRCNAELGGRFRI
Mb1267|M.bovis_AF2122/97            TTAAA-----ACGADSQGLVVSFYTPATDGATFTAIAQRCNQQFGGRFTI
Rv1235|M.tuberculosis_H37Rv         TTAAA-----ACGADSQGLVVSFYTPATDGATFTAIAQRCNQQFGGRFTI
MAV_1374|M.avium_104                TIAAASS---ACAAGPRGLVISFYTTATDGATFAAIAQDCTRQFGGRFAI
MMAR_4206|M.marinum_M               TIASALLALPACRSGNSGLVIGFYTPSADATTFAAVAQRCSERAAGRYTI
MLBr_01086|M.leprae_Br4923          TLASVVL---ACGAGGDQLVISFYTPASEDATFTEVARRCTEQFDGRFAI
MAB_1372|M.abscessus_ATCC_1997      TLASLTG----CARSDDQIVIRFYTPASEAGTFSAAAQRCNRELGGRFTI
Mflv_3851|M.gilvum_PYR-GCK          VAASLLS---GCGAQSGPPTLTWYILPDNGGS-VARAEQCAEASNGAYQV
Mvan_2544|M.vanbaalenii_PYR-1       IAASLLS---GCGSQGGPPTLTWYILPDNGGS-VARAEQCAEASNGAYQV
                                      *:       *       .: :*  . :  :    *. *     * : :

MSMEG_5061|M.smegmatis_MC2_155      AQRNLPKGADDQRLQLARRLTGNDKSLDVMALDVVWTAEFAEAGWAVPLS
TH_2061|M.thermoresistible__bu      EQRSLPREADAQRLQLARRLTGNDRSLDVMALDVVWTAEFAEAGWALPLS
Mb1267|M.bovis_AF2122/97            AQVSLPRSPNEQRLQLARRLTGNDRTLDVMALDVVWTAEFAEAGWALPLS
Rv1235|M.tuberculosis_H37Rv         AQVSLPRSPNEQRLQLARRLTGNDRTLDVMALDVVWTAEFAEAGWALPLS
MAV_1374|M.avium_104                QQISLPRAPGEQRLQLARRLTGRDRTLDIMSLDVVWTAEFAEAGWALPLS
MMAR_4206|M.marinum_M               AYVGLPRSPDEQRLQLARRLAGNDRTLDVMGLDVMWTAEFAEAGWALPLS
MLBr_01086|M.leprae_Br4923          QHVSLPRSPDEQRLQLARRLTGKDRSLDVMAMDVVWTAEFAEAGWTLPLS
MAB_1372|M.abscessus_ATCC_1997      LQVSLPKRADEQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLS
Mflv_3851|M.gilvum_PYR-GCK          RIESLPSTATAQREQMVRRLAAGDSSIDLVSMDVVFTAEFANAGFLRPYT
Mvan_2544|M.vanbaalenii_PYR-1       RIESLPSTATAQREQMVRRLAAGDSSIDLVSMDVVFTAEFANAGFLRPYT
                                       .**  .  ** *:.***:. * ::*::.:**::*****:**:  * :

MSMEG_5061|M.smegmatis_MC2_155      EDPAGLAEADATENTLPGPLETARWQDELYAAPITTNTQLLWYRADLMPA
TH_2061|M.thermoresistible__bu      EDPAGLAEADATTNTLPGPLETAKWNGELYAAPITTNTQLLWYRADLMDE
Mb1267|M.bovis_AF2122/97            DDPAGLAENDAVADTLPGPLATAGWNHKLYAAPVTTNTQLLWYRPDLVNS
Rv1235|M.tuberculosis_H37Rv         DDPAGLAENDAVADTLPGPLATAGWNHKLYAAPVTTNTQLLWYRPDLVNS
MAV_1374|M.avium_104                DDPAARAEADATVDTLPGPLSTARWHDRLFAAPVTTNTQLLWYRPDLVPQ
MMAR_4206|M.marinum_M               EDPAGLAETDATIDTLPGPLKTATWKHRLYAAPVTTNTQLLWYRPDLVAQ
MLBr_01086|M.leprae_Br4923          EDPAGLAEPDAIVDTLPGPLATATWKRKLYAAPVTTNTQLLWYRTDLVDQ
MAB_1372|M.abscessus_ATCC_1997      DDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQLLWYRKDLVPE
Mflv_3851|M.gilvum_PYR-GCK          AEET----SRLTAGMLPAPIETGMWEDTLYGAPYKSNAQLLWYRKSAAAA
Mvan_2544|M.vanbaalenii_PYR-1       EEET----SRLTAGMLPAPVETGMWEDTLYGAPYKSNTQLLWYRKSHAAA
                                     : :         . *..*: :. *.  *:.** .:*:****** .    

MSMEG_5061|M.smegmatis_MC2_155      P--PTTWDGMLDEANRLYREGGPSWIAVQGKQYEGMVVWFNTLLQSAGGQ
TH_2061|M.thermoresistible__bu      P--PATWDEMLSEAARLHAQGGPSWIAVQGKQYEGLVVWFNTLLESAGGQ
Mb1267|M.bovis_AF2122/97            P--PTDWNAMIAEAARLHAAGEPSWIAVQANQGEGLVVWFNTLLVSAGGS
Rv1235|M.tuberculosis_H37Rv         P--PTDWNAMIAEAARLHAAGEPSWIAVQANQGEGLVVWFNTLLVSAGGS
MAV_1374|M.avium_104                P--PRTWDAVVTEAARLHAAGQPSWIAVQANEGEGLVVWFNTLLASGGGR
MMAR_4206|M.marinum_M               P--PETWNAVVAEAGRLRAAGQPTWIAVQANQGEGLMVWFNTVLSSVGGQ
MLBr_01086|M.leprae_Br4923          P--PGDWNGMVAEAARLHAAGEPSWIAVQANQGEGLVVWFNTLLASAGGQ
MAB_1372|M.abscessus_ATCC_1997      P--PATWDQTVREAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGS
Mflv_3851|M.gilvum_PYR-GCK          AGVDPASPTFTWDEMLKAAVGQQKKIAVQAQRYEGYTVLINALVLSGGGA
Mvan_2544|M.vanbaalenii_PYR-1       AGVDPASPTFTWDEMLKAAEQQQKKIAVQAQRYEGYTVWINALVLSGGGE
                                    .           :          . **:*.:. **  * :*::: * ** 

MSMEG_5061|M.smegmatis_MC2_155      VLSDDGQRVTLTDTPEHRAATVKALRIIKSVATAPGADPSITQTDENTAR
TH_2061|M.thermoresistible__bu      VLSDDGQRVTLTDTPEHRAATVKALEIIKAVATAPGADPSITQTDENTAR
Mb1267|M.bovis_AF2122/97            VLSEDGRHVTLTDTPAHRAATVSALQILKSVATTPGADPSITRTEEGSAR
Rv1235|M.tuberculosis_H37Rv         VLSEDGRHVTLTDTPAHRAATVSALQILKSVATTPGADPSITRTEEGSAR
MAV_1374|M.avium_104                VLSEDGRRVTLTDTPAHRAATVNALRILKSVATAPGADPSITRTDEGTAR
MMAR_4206|M.marinum_M               VLSDDGTRVTLTDTPAHRAATVAALRVLKSVATAPGADPSITRAEAGTAR
MLBr_01086|M.leprae_Br4923          VLSEDGRHVTLTDTPEHRAATVRALRIIKAVATVPGADPSITRTDEATAR
MAB_1372|M.abscessus_ATCC_1997      VLAGDGKTVTLTDTPAHRQATVTALRTMKSIATADGADPSITQTDEGTAR
Mflv_3851|M.gilvum_PYR-GCK          LLEDVEAGRDAKPS-LNTPPGLKAAEIVGTLGRSPAAPTDMSNASEEQAR
Mvan_2544|M.vanbaalenii_PYR-1       LLQDVEAGRNAKPS-MATPPGEKAAEIVGNLGRSSAAPTDLSNASEEQAR
                                    :*         . :     .   * . :  :.   .* ..::.:.   **

MSMEG_5061|M.smegmatis_MC2_155      LALEQGKAALEVNWPYVLPSLLENAVKGGVSFLPLDGDPALQGSINDVGT
TH_2061|M.thermoresistible__bu      LALEQGRAALEVNWPYVLPSLLENAIKGGVGFLPLNENPALRGSINDVGT
Mb1267|M.bovis_AF2122/97            LAFEQGKAALEVNWPFVFASMLENAVKGGVPFLPLNRIPQLAGSINDIGT
Rv1235|M.tuberculosis_H37Rv         LAFEQGKAALEVNWPFVFASMLENAVKGGVPFLPLNRIPQLAGSINDIGT
MAV_1374|M.avium_104                LAVEQGRAALAVNWPYALASMLDNAVKGGVPFLPLNRDPRLAGSINDVGI
MMAR_4206|M.marinum_M               LAFEQGKAALELNWPYVFASMLENAVKGGVPFLPLDRLPELAGSINDVGT
MLBr_01086|M.leprae_Br4923          LAVEQGKAALEVNWPFVLASMLENAVKGGVAFLPLDRISELAGSINNVGT
MAB_1372|M.abscessus_ATCC_1997      LAFEQGKAAFEINWPFVMASMMENAIKGGVPFLRLDRRPDLTGAIGDAGR
Mflv_3851|M.gilvum_PYR-GCK          ANFQSDQGMFMVNWPYVLAAARSAAEEGTLPQEVVDD-------------
Mvan_2544|M.vanbaalenii_PYR-1       ANFQSDQGMFMVNWPYVLAAARSAAEEGTLPQAVVDD-------------
                                      .:..:. : :***:.:.:  . * :* :    ::              

MSMEG_5061|M.smegmatis_MC2_155      FSPTDEQFDIAFDASKKVFGFAPYPGVNPDEPARVTLGGLNLAVASTSQH
TH_2061|M.thermoresistible__bu      FAPTDEQFDLALNASKEVFGFARYPGVRPDEPARVTLGGLNLAVASTTRH
Mb1267|M.bovis_AF2122/97            FTPSDEQFRIAYDASQQVFGFAPYPAVAPGQPAKVTIGGLNLAVAKTTRH
Rv1235|M.tuberculosis_H37Rv         FTPSDEQFRIAYDASQQVFGFAPYPAVAPGQPAKVTIGGLNLAVAKTTRH
MAV_1374|M.avium_104                FVPTDEQYRIAYQASQKVFGFAPYPGAAPGLPAKVTIGGANLAVASTTRH
MMAR_4206|M.marinum_M               FVPTDEQFRIAYLASQKVFGFAPYPAVLPGRPARVTIGGLNLAVASTSRH
MLBr_01086|M.leprae_Br4923          FVPNDEQFRIAYQATRNVFGFAPYPSVSRSEPAKVTIGGLNLAVASTSRH
MAB_1372|M.abscessus_ATCC_1997      FAPSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNIAVAKTTRY
Mflv_3851|M.gilvum_PYR-GCK          ------------------IGWARYPRVSPDMPSAPPLGGANLGIGAYTEY
Mvan_2544|M.vanbaalenii_PYR-1       ------------------IGWARYPRVSPDRPSAPPLGGANLGIGAYTKH
                                                      :*:* :* .  . *:  .:** *:.:.  :.:

MSMEG_5061|M.smegmatis_MC2_155      KAEAFEAIRCLRNVENQRYTSIEGGLPAVRTSLYDDPAFQKKYPQYEIIR
TH_2061|M.thermoresistible__bu      KAEAFEAVRCLRNEENQRLTSIEGGLPAVRTSLYDDPQFQAKYPQYEIIR
Mb1267|M.bovis_AF2122/97            RAEAFEAVRCLRDQHNQRYVSLEGGLPAVRASLYSDPQFQAKYPMHAIIR
Rv1235|M.tuberculosis_H37Rv         RAEAFEAVRCLRDQHNQRYVSLEGGLPAVRASLYSDPQFQAKYPMHAIIR
MAV_1374|M.avium_104                RAEAFEAIRCVRSLQHQKYVAIQGGLPPVRTSLYSDPQFQTKYPMYTIIR
MMAR_4206|M.marinum_M               KAEAFEAVRCLRDPQSQKRLAIEGGLPAVRTSLYADPQFQAKYPMYRIIR
MLBr_01086|M.leprae_Br4923          KAEAFEAVRCLRSEQSQQYLSIEGGLPAVRASLYSDPAFQDKYPMYTIIR
MAB_1372|M.abscessus_ATCC_1997      KAQAFEALNCLRSRENQKATAIEGGLPAVDSSLYDDPEFQAKYPAYAIIR
Mflv_3851|M.gilvum_PYR-GCK          PEEAVALVECINAEPKATQYMLDESEPSPYAASYDNPEIRETYENADLIR
Mvan_2544|M.vanbaalenii_PYR-1       PDQAVALVECINAEPKATQYMLDESEPSPYAASYDNPEIRETYENADLIR
                                      :*.  :.*:.         :: . *.  :: * :* :: .*    :**

MSMEG_5061|M.smegmatis_MC2_155      QQLTNAAVRPATPVYQAVSTRMSATLAPISDIDPERTADELTEAVQKAID
TH_2061|M.thermoresistible__bu      DQLINAAVRPATPVYQAMSTRMSATLAPISQIDPERTADELAEQVQQAID
Mb1267|M.bovis_AF2122/97            QQLTDAAVRPATPVYQALSIRLAAVLSPITEIDPESTADELAAQAQKAID
Rv1235|M.tuberculosis_H37Rv         QQLTDAAVRPATPVYQALSIRLAAVLSPITEIDPESTADELAAQAQKAID
MAV_1374|M.avium_104                RQLTDAAVRPATPVYQTVSIRLASTLSPITGIDPERTADQLSAEVQKAID
MMAR_4206|M.marinum_M               QQLTEAAVRPATPVYQAVSLRLSAELSPVTEIDPERTADKLAAQVQQAID
MLBr_01086|M.leprae_Br4923          QQLTDAAVRPVTPAYQAVSIRLSAALNPITDIDPEPMADRLAAQVQKAID
MAB_1372|M.abscessus_ATCC_1997      DQLANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVD
Mflv_3851|M.gilvum_PYR-GCK          ESIGDGGPRPPTPFYTDISGAIQQTWHPPASVT-SETPERTDQFMADVLA
Mvan_2544|M.vanbaalenii_PYR-1       ESIGEGGPRPPTPFYTDISGAIQQTWHPPASVN-AETPERTDQFMADVLA
                                     .: :.. ** :* *  :*  :     * : :     .:       ..: 

MSMEG_5061|M.smegmatis_MC2_155      GKGLIP
TH_2061|M.thermoresistible__bu      GKGLIP
Mb1267|M.bovis_AF2122/97            GMGLLP
Rv1235|M.tuberculosis_H37Rv         GMGLLP
MAV_1374|M.avium_104                GKGLLP
MMAR_4206|M.marinum_M               GKGLLP
MLBr_01086|M.leprae_Br4923          GKGLLP
MAB_1372|M.abscessus_ATCC_1997      GRGLIP
Mflv_3851|M.gilvum_PYR-GCK          GRRLL-
Mvan_2544|M.vanbaalenii_PYR-1       GRRLL-
                                    *  *: