For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4888 (-)

SQGRPSRPTVRPTKADVARLANVSTATVSYVLNNVAGQRISEQTQEAVRRAAAELGYRPNLAARNLASGG
SGVVLYIVGRLSLGNLPIEVGSRLTTALARHGIVLSLQFETDDDRNVVDAIADLNPMAITSTFPLTGNAL
AAATAAGIPQIHLGSSQLHAIGALDRSIGEMRVEHLRARGHTRLAFAYTTDEQLRPLGDYWLAGLHAAAQ
KRGLPEIAVASVASDGSNAADVVTRWAEAGVTAICAQSDETAFVVLHGLRNAGLRCPRDMAVMGVNAIEL
GAVSAPPLTSVSFDAKAIVDVAVAAMMSELGYPTESEPSDIDVATLIVRDST*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_4888	-	-	100% (333)	ligand-binding /sugar binding domain-containing protein
M. smegmatis MC2 155	MSMEG_1708	-	2e-17	27.25% (345)	ribose operon repressor, putative
M. smegmatis MC2 155	MSMEG_0491	-	4e-17	28.93% (318)	transcriptional regulator, LacI family protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	MAV_5263	-	5e-98	56.88% (327)	transcriptional regulator, LacI family protein
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_2545	-	4e-15	27.03% (344)	periplasmic binding protein/LacI transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4888|M.smegmatis_MC2_155      MS--QGR---PSRPTVRPTKADVARLANVSTATVSYVLNNVAGQRISEQT
MAV_5263|M.avium_104                MTGPQGNGNSSSNKAARPTTADVARLAGVSTATVSYVLNNARGRRISPDT
Mvan_2545|M.vanbaalenii_PYR-1       -----------MIPKQTVNMTDVARRSGVSIASVSRALRGESG--VSAAT
                                                      . :**** :.** *:** .*..  *  :*  *

MSMEG_4888|M.smegmatis_MC2_155      QEAVRRAAAELGYRPNLAARNLASGGSGVVLYIVGRLSLGNLP-IEVGSR
MAV_5263|M.avium_104                RDAVYRAAKLLGYRPNLAARNLARGKSGVVLYVVPHVAVGEMP-MQAGSR
Mvan_2545|M.vanbaalenii_PYR-1       RDRILSAARELAYVVSPEASRLSGGPTGRVGVIVPRVDAWFYSTILAGIA
                                    :: :  **  *.*  .  * .*: * :* *  :* ::     . : .*  

MSMEG_4888|M.smegmatis_MC2_155      LTTALARHGIVLSLQFETDDDRNVVDAIAD--LNPMAITSTFPLTGNALA
MAV_5263|M.avium_104                MTTALAREGLLQVQVFETDDDQHVVDAIAN--LDPVAVTSLFPLSAAARR
Mvan_2545|M.vanbaalenii_PYR-1       DEFDTVGMDLILCTLPTSAARHRFFEALPLRRKVDAAVVVSLPLSARERT
                                         .  .::      :   :...:*:.       *:.  :**:.    

MSMEG_4888|M.smegmatis_MC2_155      AATAAGIPQIHLGSS----QLHAIGALDRSIGEMRVEHLRARGHTRLAFA
MAV_5263|M.avium_104                AVTEAGIPHIEIG------TLPALNDPHLSVGEMRIAHLVERGHRRIAFA
Mvan_2545|M.vanbaalenii_PYR-1       RLDQLAVPTVFVGGHRTEDHRPWVGIDDERAAQQAVGHLLRIGHHDIAMI
                                         .:* : :*          :.  .   .:  : **   **  :*: 

MSMEG_4888|M.smegmatis_MC2_155      YTTDEQLRPLG--DYWLAGLHAAAQKRGLPEIAVASVASDGSNAADVVTR
MAV_5263|M.avium_104                YTGIARWRPLG--DYWFEGVSRAARLRGLPPVRADEVILD--TAASVVSA
Mvan_2545|M.vanbaalenii_PYR-1       QAADDTDIPWATDQARIRGFHQTMQEAGLADPTVVTVKWSVDGGSHGMET
                                     :      * .  :  : *.  : :  **.   .  *  .   .:  :  

MSMEG_4888|M.smegmatis_MC2_155      WAEAG--VTAICAQSDETAFVVLHGLRNAGLRCPRDMAVMGVNAIELGAV
MAV_5263|M.avium_104                WVRDG--VTAVCAQSDEIACLVLYGIHQAGLRCPGDLAVMGVDASPMGMV
Mvan_2545|M.vanbaalenii_PYR-1       LLSRSRPPTAVFCHSDEIALGALRTLRRSGISVPQQVSVIGVDDHPAAEL
                                        .   **: .:*** *  .*  ::.:*:  * :::*:**:    . :

MSMEG_4888|M.smegmatis_MC2_155      SAPPLTSVSFDAKAIVDVAVAAMMSELG---YPTESEPSDIDVATLIVRD
MAV_5263|M.avium_104                STPPLTTVQFDPCAVADAALAAVFERLG---HAAPPSPELTDIARLVVRS
Mvan_2545|M.vanbaalenii_PYR-1       SD--LTTVAQPVREQGRIAARVVLGGLGDGDASGPPASVTTLPTRLVVRG
                                    *   **:*          *  .::  **    .  . .     : *:**.

MSMEG_4888|M.smegmatis_MC2_155      ST----
MAV_5263|M.avium_104                ST----
Mvan_2545|M.vanbaalenii_PYR-1       STAPPR
                                    **