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VASSDGTARSAPHPRVVLADGVPMSALVAEAPEPRAVVVALHGGATTSAYFDCPGHPELSLLHAGVAAGF TVVALDRPGYGASAPYPEAMARPEQRLALAFGALERIVGTQDLFLLGHSMGCELAVRMAISGARVVGISL AGTGRRYQSAGRDILKDASSDHRPRGLRELLWEPARLYPPDVLGSGLSAGGAAYEGEVVKTWSWQDFPQL AALVKVPAQFIAGDHENVWEAGTDALAAIGAMFTASPRVAVEVLPESGHNLSVGLTAAEYHQRVLSFAAE CLDVRATRAGTDVEVEAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4815 | - | - | 100% (298) | hypothetical protein MSMEG_4815 |
| M. smegmatis MC2 155 | MSMEG_3289 | - | 3e-05 | 30.51% (118) | gp61 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1973 | ephB | 2e-05 | 30.15% (136) | epoxide hydrolase EphB |
| M. gilvum PYR-GCK | Mflv_2482 | - | 1e-90 | 56.79% (287) | hypothetical protein Mflv_2482 |
| M. tuberculosis H37Rv | Rv1938 | ephB | 2e-05 | 30.15% (136) | epoxide hydrolase EphB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2045 | - | 4e-05 | 26.64% (214) | putative hydrolase (alpha/beta fold) |
| M. marinum M | MMAR_4732 | - | 6e-81 | 54.26% (282) | thioesterase |
| M. avium 104 | MAV_0918 | - | 2e-91 | 58.06% (279) | hypothetical protein MAV_0918 |
| M. thermoresistible (build 8) | TH_3915 | - | 6e-37 | 47.09% (189) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4172 | - | 9e-93 | 57.29% (288) | hypothetical protein Mvan_4172 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1973|M.bovis_AF2122/97 ---------MSQVHRILNCRGTRIHAVADSPPDQ--QGPLVVLLHG----
Rv1938|M.tuberculosis_H37Rv ---------MSQVHRILNCRGTRIHAVADSPPDQ--QGPLVVLLHG----
MSMEG_4815|M.smegmatis_MC2_155 MASSDGTARSAPHPRVVLADGVPMSALVAEAPE---PRAVVVALHGGATT
TH_3915|M.thermoresistible__bu --------------------------------------------------
MMAR_4732|M.marinum_M ------MNQALVRPRVVIVDGVPMSGLLAEAADPTGPKATVVALHGGGTS
MAV_0918|M.avium_104 ------MNGAAPRPRLVIVDGVPMSALVAEAED---PKAVLVAIHGGGTT
Mflv_2482|M.gilvum_PYR-GCK ----MTAGAGVPRPRVVLVDGVPMSALAVQVPD---PRAVIVAIHGGATS
Mvan_4172|M.vanbaalenii_PYR-1 ----MTSES--PRPRVVLVDGVPMSALVAQAPD---PRAVILAVHGGATS
MAB_2045|M.abscessus_ATCC_1997 --MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAPRAVVLLLHGG---
Mb1973|M.bovis_AF2122/97 ---FPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKEL
Rv1938|M.tuberculosis_H37Rv ---FPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQKAYRIKEL
MSMEG_4815|M.smegmatis_MC2_155 SAYFDCPGHPELSLLHAGVAAGFTVVALDRPGYGASAPYPEAMARPEQRL
TH_3915|M.thermoresistible__bu -------------MLG------------DRP-------------------
MMAR_4732|M.marinum_M SSYFDCPGHPQLSLLRLGATLGFTVVALDRPGHGSSAPYPEAMQHPEQRV
MAV_0918|M.avium_104 AVYFDCPGHPSFSLLRAGATAGFTVVALDRPGYGSSAPYPGAMTRPEQRV
Mflv_2482|M.gilvum_PYR-GCK SAYFDCPGRPELSLLRAAGAAGFTAIALDRPGYGSSAVYAGEFTDPGRRV
Mvan_4172|M.vanbaalenii_PYR-1 SAYFDCPGRPDLSLLRAAATAGFTTIALDRPGYGTSAVYAAEFADPARRV
MAB_2045|M.abscessus_ATCC_1997 ----GQSRHAWDVTAQRLHQRGYTVAAYDTRGHGDSD-WDPDGRYDMDRL
*
Mb1973|M.bovis_AF2122/97 VGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFA
Rv1938|M.tuberculosis_H37Rv VGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGVVGISVPFA
MSMEG_4815|M.smegmatis_MC2_155 ALAFGALERIVGT--------------QDLFLLGHSMGCELAVRMAIS--
TH_3915|M.thermoresistible__bu ----------TG---------------HGVFVLAHSNGCELAVRLAAAER
MMAR_4732|M.marinum_M DLAFGAIDRMLDQR----------PRGAGLFLMGHSGGCELVLRMATSPR
MAV_0918|M.avium_104 ELAYGAVDRILGQR----------PRGAGLFLMGHSGGCELVLRMAADER
Mflv_2482|M.gilvum_PYR-GCK AAAAGTIDKILGDS----------DRGAGLFLLGHSAGCELTLRMATG--
Mvan_4172|M.vanbaalenii_PYR-1 ASSFAAVDKILAGA----------DRGAGLFVLGHSAGCELALRMATS--
MAB_2045|M.abscessus_ATCC_1997 GSDLLAVRSYADSG-------------RPVAAIGASLGGLTILGTHLLAP
. :
Mb1973|M.bovis_AF2122/97 GRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDL
Rv1938|M.tuberculosis_H37Rv GRGVIGLPGSPFGERRPSDYHLELAGPGRVWYQDYFAVQDGIITEIEEDL
MSMEG_4815|M.smegmatis_MC2_155 GARVVGISLAGTGRRYQS--------------AGRDILKDASSDHRPRGL
TH_3915|M.thermoresistible__bu GGELLGMALAGTGLRYEP--------------AAAEILKAASPTNRPVGL
MMAR_4732|M.marinum_M AADLLGVELGGTGRRYHP--------------AAKEVMRLAALQDRPPGV
MAV_0918|M.avium_104 GADLLGIELAGTGRHYHP--------------AAREILKTATRERRPAGL
Mflv_2482|M.gilvum_PYR-GCK RDDVVGVELSGTGLRYTP--------------QARDIIRDATVTSRPAGL
Mvan_4172|M.vanbaalenii_PYR-1 GDDVVGVELAGTGLRYGE--------------KAKDVIATATVTNRPAGL
MAB_2045|M.abscessus_ATCC_1997 PDLWQAVVLVDVTPRMEM---------------DGARRVVAFMSAHPEGF
.: : . ..
Mb1973|M.bovis_AF2122/97 RGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGA
Rv1938|M.tuberculosis_H37Rv RGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRAGPLCMAEGA
MSMEG_4815|M.smegmatis_MC2_155 RELLWEPARLYPPDVLGSGLSAG---GAAYEGEVVKTWSWQDFPQLAALV
TH_3915|M.thermoresistible__bu RELLWEPAAVYPPEVLAELPSAAS--GAPYEAALVAGWPRRDFRELA---
MMAR_4732|M.marinum_M RELLWEPMHLYPDDIRRGITNSST--APRYERTVALNWPNQDFPALAPGV
MAV_0918|M.avium_104 RELLWHPENLYPPEVLGGATVSPS--APSYEDQMVSNWARRDFPALAPAV
Mflv_2482|M.gilvum_PYR-GCK RDLLWTPTDLYPAEVLTGALSAP---GVAYEGDVTAHWAGRDFPALAERL
Mvan_4172|M.vanbaalenii_PYR-1 RDLLWEPTDLYPAEVLTGALSAP---GVAYEGDVTANWARRDFPAIAADV
MAB_2045|M.abscessus_ATCC_1997 DSLESAADVIAAYNPHRPRPENLDGLRKVLARREDGRWSWRWDPAFVTSN
. : :.
Mb1973|M.bovis_AF2122/97 RLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDL
Rv1938|M.tuberculosis_H37Rv RLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYHNIDNDWHDL
MSMEG_4815|M.smegmatis_MC2_155 KVPAQFIAGDHENVWEAGTDALAAIGAMFTAS---PRVAVEVLPESGHNL
TH_3915|M.thermoresistible__bu ---------------------------LFAAS---PRVVTDEILGAGHNL
MMAR_4732|M.marinum_M RVPVRFTLGEHDNVFRADPSALAEIADMFSAT---EHFVNSRPPGAGHNL
MAV_0918|M.avium_104 RVPVHFSIAEHEKVWQNDASAMDEIAALFTGA---PEFTVHRQPGAGHNI
Mflv_2482|M.gilvum_PYR-GCK TTPVQFSVADNEKVWQSSPEALAAITALFSAS---PRVRINRMNDSGHNL
Mvan_4172|M.vanbaalenii_PYR-1 RVPVQFSIAEHEKVWETDPEAVSAIAGLFTAS---PRVRINEVAASGHNL
MAB_2045|M.abscessus_ATCC_1997 FQFLQGDPDEGAEYFEMMSAFLLDGARQVSAP---TLLVRGLLSDIVSEE
. :
Mb1973|M.bovis_AF2122/97 ADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPN-----------
Rv1938|M.tuberculosis_H37Rv ADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPN-----------
MSMEG_4815|M.smegmatis_MC2_155 SVG----------LTAAEYHQRVLSFAAECLDVRAT--------------
TH_3915|M.thermoresistible__bu SLG----------WTAAAYHLRVLSFVAECVAARQ---------------
MMAR_4732|M.marinum_M SLG----------HTAADYHRQVLSFVEDCASARPP--------------
MAV_0918|M.avium_104 SLG----------YTAADYHATVLSFANACATAGPAPNVKLASRSASNVK
Mflv_2482|M.gilvum_PYR-GCK SVG----------LTAGDYHRNVLSFTEECISDAPG--------------
Mvan_4172|M.vanbaalenii_PYR-1 SVG----------LTAGEYHRTVMSFIDECIAAADG--------------
MAB_2045|M.abscessus_ATCC_1997 TVR--------HFLTVVPHAQTVDVSGAGHMIAGDN--------------
: : .
Mb1973|M.bovis_AF2122/97 -----YRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP--
Rv1938|M.tuberculosis_H37Rv -----YRGTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP--
MSMEG_4815|M.smegmatis_MC2_155 -----RAGTDVEVEAG--------------------------
TH_3915|M.thermoresistible__bu -----RGRTGMEVEAG--------------------------
MMAR_4732|M.marinum_M -------DGDAAAAAG--------------------------
MAV_0918|M.avium_104 LASRSAADGEPAADGEPAEDGEQAEDREQAAHETTAAQEEAG
Mflv_2482|M.gilvum_PYR-GCK -------RDREEVEAS--------------------------
Mvan_4172|M.vanbaalenii_PYR-1 -------RDREQVEAS--------------------------
MAB_2045|M.abscessus_ATCC_1997 -------NDAFSTAVVEFLDRTI-------------------
.