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M. smegmatis MC2 155 MSMEG_4691 (-)

annotation: HNH nuclease
coordinates: 4777394 - 4777744
length: 116

VAVSRTRSARYARRRKRRLDAVVNDLTPAQWEAIKQAWGGCAYCGATGGPFQKDCVMAISRGGRYTVDNV
VPACGSCNASKCNDEVTGWLRRKRLDERRFLTRYVEIRARLTAQFA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4691--100% (116)HNH nuclease
M. smegmatis MC2 155MSMEG_2148-1e-0634.09% (88) HNH endonuclease domain-containing protein
M. smegmatis MC2 155MSMEG_4694-4e-0542.59% (54) HNH endonuclease family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2576-6e-4878.38% (111) HNH nuclease
M. tuberculosis H37Rv-----
M. leprae Br4923MLBr_01254-2e-0540.00% (55) hypothetical protein MLBr_01254
M. abscessus ATCC 19977MAB_1343-7e-4067.92% (106) hypothetical protein MAB_1343
M. marinum MMMAR_3820-7e-0540.00% (55) hypothetical protein MMAR_3820
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3745-5e-0540.00% (55) hypothetical protein MUL_3745
M. vanbaalenii PYR-1Mvan_4058-2e-4876.32% (114) HNH nuclease

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2576|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4058|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4691|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1343|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3820|M.marinum_M               MAQGKKRRGHRNHGAAASMTGTA--SCLHSVDTHPPNRHETASIWSRRRV
MUL_3745|M.ulcerans_Agy99           MAQGKKRRGHRNHGAAANMTGTA--SCLHSVDTHPPNRHETASIWSRRRV
MLBr_01254|M.leprae_Br4923          MVQRKNRRSHRSSGAAANLIRAANPSSLHNVDIHPSTCYESGSIWNRRRV
                                                                                      

Mflv_2576|M.gilvum_PYR-GCK          --------------MRQRA---------LVARERT-YAHAVAVNNSRRAR
Mvan_4058|M.vanbaalenii_PYR-1       --------------MRACVSAGDTPGTWPISRTLTPHALGVAVNNSRRAR
MSMEG_4691|M.smegmatis_MC2_155      ----------------------------------------MAVSRTRSAR
MAB_1343|M.abscessus_ATCC_1997      ------------------------------------------MAGTRRAR
MMAR_3820|M.marinum_M               LLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHSATRTIVVPS
MUL_3745|M.ulcerans_Agy99           LLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHSATQTIVVPS
MLBr_01254|M.leprae_Br4923          LLLNSTYEPLTALPTRRAIIMVICGKADVVHVDPAGPVVHSATRSITVPS
                                                                                    . 

Mflv_2576|M.gilvum_PYR-GCK          AARRRKRRVAAAVNDLTDAQWASIKAAWEGCAYCGKTTGTMQRDCVMAIS
Mvan_4058|M.vanbaalenii_PYR-1       AARRRKRRVAAVVNDLTDEQWAAIRAAWNGCAYCGKTAGTMQRDCVMAIS
MSMEG_4691|M.smegmatis_MC2_155      YARRRKRRLDAVVNDLTPAQWEAIKQAWGGCAYCGATGGPFQKDCVMAIS
MAB_1343|M.abscessus_ATCC_1997      IAKRRRLRVSRADNDLTDAQWSQLVQAWGGCAYCGATGTALQRDCVQPIS
MMAR_3820|M.marinum_M               VIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTVD--HVVPRS
MUL_3745|M.ulcerans_Agy99           VIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTVD--HVVPRS
MLBr_01254|M.leprae_Br4923          VIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTVD--HVVPRS
                                      : *          :.  :   :      ***** .  ..:   * . *

Mflv_2576|M.gilvum_PYR-GCK          RGGRYTVDNVVPACGACNASKCN---DEVTGWLRRKRYDERLFLERYVRI
Mvan_4058|M.vanbaalenii_PYR-1       RGGRYTVDNVVPACAACNASKCN---DEVTGWLRRKRLDERLFLERYVRI
MSMEG_4691|M.smegmatis_MC2_155      RGGRYTVDNVVPACGSCNASKCN---DEVTGWLRRKRLDERRFLTRYVEI
MAB_1343|M.abscessus_ATCC_1997      RGGRYTQANVVPACGSCNSSKCN---AEVTSWMRRKRLDETAFLRRYVEV
MMAR_3820|M.marinum_M               RGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPTGQHWRLLST
MUL_3745|M.ulcerans_Agy99           RGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPTGQHWRLLST
MLBr_01254|M.leprae_Br4923          RGGDHSWENCVACCSTCNHRKGDKLLTELGWVLRRTPVLPTGQHWRLLST
                                    *** ::  * *..*.:**  * :    *:   :**.         * :  

Mflv_2576|M.gilvum_PYR-GCK          RAELMPAERETALTVAPEAGSLP
Mvan_4058|M.vanbaalenii_PYR-1       RAELV-GEREAGAVDQS------
MSMEG_4691|M.smegmatis_MC2_155      RARLT-----AQFA---------
MAB_1343|M.abscessus_ATCC_1997      TQALA------------------
MMAR_3820|M.marinum_M               IKELDPSWARYLGEGAA------
MUL_3745|M.ulcerans_Agy99           IKELDPSWARYLGEGAA------
MLBr_01254|M.leprae_Br4923          VKELDPAWARYLGGGAA------
                                       *