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VRACVSAGDTPGTWPISRTLTPHALGVAVNNSRRARAARRRKRRVAAVVNDLTDEQWAAIRAAWNGCAYC GKTAGTMQRDCVMAISRGGRYTVDNVVPACAACNASKCNDEVTGWLRRKRLDERLFLERYVRIRAELVGE REAGAVDQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4058 | - | - | 100% (149) | HNH nuclease |
| M. vanbaalenii PYR-1 | Mvan_4063 | - | 6e-05 | 43.14% (51) | HNH endonuclease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2496c | - | 3e-05 | 41.82% (55) | hypothetical protein Mb2496c |
| M. gilvum PYR-GCK | Mflv_2576 | - | 1e-58 | 88.43% (121) | HNH nuclease |
| M. tuberculosis H37Rv | Rv2469c | - | 3e-05 | 41.82% (55) | hypothetical protein Rv2469c |
| M. leprae Br4923 | MLBr_01254 | - | 5e-06 | 41.82% (55) | hypothetical protein MLBr_01254 |
| M. abscessus ATCC 19977 | MAB_1343 | - | 4e-37 | 63.21% (106) | hypothetical protein MAB_1343 |
| M. marinum M | MMAR_3820 | - | 7e-06 | 43.64% (55) | hypothetical protein MMAR_3820 |
| M. avium 104 | MAV_1702 | - | 8e-05 | 40.00% (55) | HNH endonuclease family protein |
| M. smegmatis MC2 155 | MSMEG_4691 | - | 4e-48 | 76.32% (114) | HNH nuclease |
| M. thermoresistible (build 8) | TH_0922 | - | 6e-06 | 44.44% (54) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3745 | - | 5e-06 | 43.64% (55) | hypothetical protein MUL_3745 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2496c|M.bovis_AF2122/97 MAHGKKRRGHRSSGVAAGVTG--PASCLHGVHSHRLASGVETHPPNRHES
Rv2469c|M.tuberculosis_H37Rv MAHGKKRRGHRSSGVAAGVTG--PASCLHSVHSHRLASGVETHPPNRHES
MMAR_3820|M.marinum_M MAQGKKRRGHRNHGAAASMTG--TASCLH---------SVDTHPPNRHET
MUL_3745|M.ulcerans_Agy99 MAQGKKRRGHRNHGAAANMTG--TASCLH---------SVDTHPPNRHET
MAV_1702|M.avium_104 MAQGKKRRRHRSQVAAAGLTGPPTASSLH---------SVETHPPTRPDS
MLBr_01254|M.leprae_Br4923 MVQRKNRRSHRSSGAAANLIRAANPSSLH---------NVDIHPSTCYES
TH_0922|M.thermoresistible__bu --------------------------------------------------
Mvan_4058|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4691|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2576|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1343|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2496c|M.bovis_AF2122/97 ASIWNRRRVLLLNSTYEPLTALSMRRAIVMVICGKADVVHEDPSGPVIHS
Rv2469c|M.tuberculosis_H37Rv ASIWNRRRVLLLNSTYEPLTALSMRRAIVMVICGKADVVHEDPSGPVIHS
MMAR_3820|M.marinum_M ASIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHS
MUL_3745|M.ulcerans_Agy99 ASIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHS
MAV_1702|M.avium_104 TSIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHHDPAGPVIHS
MLBr_01254|M.leprae_Br4923 GSIWNRRRVLLLNSTYEPLTALPTRRAIIMVICGKADVVHVDPAGPVVHS
TH_0922|M.thermoresistible__bu --------VLLLNSTYEPLTALTMRRALVMVLCGKADVVHDDPNGPVIHS
Mvan_4058|M.vanbaalenii_PYR-1 -----------------------MRACVSAGDTPGTWPISRTLTPHALGV
MSMEG_4691|M.smegmatis_MC2_155 -------------------------------------------------M
Mflv_2576|M.gilvum_PYR-GCK -----------------------MRQRALVARER----------TYAHAV
MAB_1343|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2496c|M.bovis_AF2122/97 STRSILVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGGKADTV
Rv2469c|M.tuberculosis_H37Rv ATRSILVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGGKADTV
MMAR_3820|M.marinum_M ATRTIVVPSVIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MUL_3745|M.ulcerans_Agy99 ATQTIVVPSVIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MAV_1702|M.avium_104 ATSSIVMPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MLBr_01254|M.leprae_Br4923 ATRSITVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
TH_0922|M.thermoresistible__bu ATRALVMPSVIRLRTYVRVPYRARVPMTRAALMHRDRFRCAYCGGKADTI
Mvan_4058|M.vanbaalenii_PYR-1 AVNNSRRARAARRRKRRVAAVVNDLTDEQWAAIRAAWNGCAYCGKTAGTM
MSMEG_4691|M.smegmatis_MC2_155 AVSRTRSARYARRRKRRLDAVVNDLTPAQWEAIKQAWGGCAYCGATGGPF
Mflv_2576|M.gilvum_PYR-GCK AVNNSRRARAARRRKRRVAAAVNDLTDAQWASIKAAWEGCAYCGKTTGTM
MAB_1343|M.abscessus_ATCC_1997 -MAGTRRARIAKRRRLRVSRADNDLTDAQWSQLVQAWGGCAYCGATGTAL
. : * :. : : ***** . ..
Mb2496c|M.bovis_AF2122/97 D--HVVPRSRGGAHSWENCVACCSPCNHRKGDRLLTELGWALRRAPLPPT
Rv2469c|M.tuberculosis_H37Rv D--HVVPRSRGGAHSWENCVACCSPCNHRKGDRLLTELGWALRRAPLPPT
MMAR_3820|M.marinum_M D--HVVPRSRGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPT
MUL_3745|M.ulcerans_Agy99 D--HVVPRSRGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPT
MAV_1702|M.avium_104 D--HVVPRSRGGDHSWENCVACCSTCNHRKGDKLLNELGWTLRRPPLPPT
MLBr_01254|M.leprae_Br4923 D--HVVPRSRGGDHSWENCVACCSTCNHRKGDKLLTELGWVLRRTPVLPT
TH_0922|M.thermoresistible__bu D--HVVPRSRGGAHSWENCVAACSACNHRKADRLLSELGWTLRAVPRPPK
Mvan_4058|M.vanbaalenii_PYR-1 QRDCVMAISRGGRYTVDNVVPACAACNASKCN---DEVTGWLRRKRLDER
MSMEG_4691|M.smegmatis_MC2_155 QKDCVMAISRGGRYTVDNVVPACGSCNASKCN---DEVTGWLRRKRLDER
Mflv_2576|M.gilvum_PYR-GCK QRDCVMAISRGGRYTVDNVVPACGACNASKCN---DEVTGWLRRKRYDER
MAB_1343|M.abscessus_ATCC_1997 QRDCVQPISRGGRYTQANVVPACGSCNSSKCN---AEVTSWMRRKRLDET
: * . **** :: * *..*..** * : *: :*
Mb2496c|M.bovis_AF2122/97 GPHWRLLSAVKELDPSWARYLG-EGAA-----
Rv2469c|M.tuberculosis_H37Rv GPHWRLLSAVKELDPSWARYLG-EGAA-----
MMAR_3820|M.marinum_M GQHWRLLSTIKELDPSWARYLG-EGAA-----
MUL_3745|M.ulcerans_Agy99 GQHWRLLSTIKELDPSWARYLG-EGAA-----
MAV_1702|M.avium_104 GQHWRLLSTVKELDPAWARYLG-EGAA-----
MLBr_01254|M.leprae_Br4923 GQHWRLLSTVKELDPAWARYLG-GGAA-----
TH_0922|M.thermoresistible__bu GQHWRLLSTVKELDPVWVRYLGGEGAA-----
Mvan_4058|M.vanbaalenii_PYR-1 LFLERYVRIRAELV-GEREAGAVDQS------
MSMEG_4691|M.smegmatis_MC2_155 RFLTRYVEIRARLT-AQFA-------------
Mflv_2576|M.gilvum_PYR-GCK LFLERYVRIRAELMPAERETALTVAPEAGSLP
MAB_1343|M.abscessus_ATCC_1997 AFLRRYVEVTQALA------------------
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