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MNQPYPGQPGNQWQHLPPQAYYGQPYPQGYYPPPPPPPKKNKTGLWVLLALLAVIVVVAGGVVAFKLYVN RDWTATFEVTGTGTTATVRYSGADRETVRKDVDLPWTQDITFSGKVKAFVLEVFPLAEDESVSCSVTVNG EVVVEKTRAPGEKVLCLGVNPDAGRFG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4679 | - | - | 100% (167) | hypothetical protein MSMEG_4679 |
| M. smegmatis MC2 155 | MSMEG_4678 | - | 3e-35 | 45.25% (179) | hypothetical protein MSMEG_4678 |
| M. smegmatis MC2 155 | MSMEG_0047 | - | 8e-06 | 43.94% (66) | hypothetical protein MSMEG_0047 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0518 | mmpS2 | 4e-06 | 28.23% (124) | membrane protein |
| M. gilvum PYR-GCK | Mflv_3028 | - | 2e-05 | 34.25% (73) | membrane family protein |
| M. tuberculosis H37Rv | Rv0506 | mmpS2 | 4e-06 | 28.23% (124) | membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0517 | - | 1e-05 | 28.00% (125) | hypothetical protein MAB_0517 |
| M. marinum M | MMAR_3360 | mmpS5_2 | 4e-06 | 31.78% (107) | transmembrane protein, MmpS5_2 |
| M. avium 104 | MAV_0542 | hflB | 1e-05 | 62.86% (35) | ATP-dependent metallopeptidase HflB |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2293 | mmpS4_1 | 7e-06 | 33.78% (74) | membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1058 | - | 7e-07 | 32.88% (73) | hypothetical protein Mvan_1058 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 MNRKNVIRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAMAQINGDNV
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 KSAQIDDREQQLRLTLKKGNGDTDNSDKVITKYPSGYAVDLFNALSAKNA
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 KVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRA
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 KQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPGRYQALGAKIPKGVL
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 LYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFDQ
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 ----------------------------------------MTDPAWQQYP
MAV_0542|M.avium_104 AKQNNPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDPRA
Mb0518|M.bovis_AF2122/97 ------------------------MRMISVSGAVKRMWLLLAIVV----V
Rv0506|M.tuberculosis_H37Rv ------------------------MRMISVSGAVKRMWLLLAIVV----V
Mflv_3028|M.gilvum_PYR-GCK --------------------------MITV---VKRVWLPVLIVV----A
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------MITV---VKRVWLPVLVIA----A
MUL_2293|M.ulcerans_Agy99 --------------------------MFTF---LKRAWVPIVVVI----A
MMAR_3360|M.marinum_M ----------------------------------MRRLSGPAILL----A
MSMEG_4679|M.smegmatis_MC2_155 ------------MNQPYPGQPGNQWQHLPPQAYYGQPYPQGYYPP----P
MAB_0517|M.abscessus_ATCC_1997 QEQWPVDEPIPYPEDPKPPKWPWIVAGISVLAVLAIALTSILVITRRTEV
MAV_0542|M.avium_104 GVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLAVHSKGKP
Mb0518|M.bovis_AF2122/97 AVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPK-------------
Rv0506|M.tuberculosis_H37Rv AVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPK-------------
Mflv_3028|M.gilvum_PYR-GCK LAIGFVSISYLRSVFGSNGAVVTP-VGSDTAEDFNPT-------------
Mvan_1058|M.vanbaalenii_PYR-1 VAVGAVTVANLRSVFGSDKAIVTP-VDADTAENFNPK-------------
MUL_2293|M.ulcerans_Agy99 VAIGGTAVDRLRGVFGSDEIFSSTGSSVETIVPFNPK-------------
MMAR_3360|M.marinum_M IGVG-----------------VAATCGVANADPFQ---------------
MSMEG_4679|M.smegmatis_MC2_155 PPPPKKNKTGLWVLLALLAVIVVVAGGVVAFKLYVNRDW-----------
MAB_0517|M.abscessus_ATCC_1997 AAPTTVTVTPSTTWTGPNDVPLPSITTTEPPPPSPPPPNPSTGVETPTTT
MAV_0542|M.avium_104 IAPDADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITSAALEEAV
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 EAPPVPTTTEAPQPVPTTGQGPGGSG------------------------
MAV_0542|M.avium_104 DRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILAR
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 GRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTGAVS
Mb0518|M.bovis_AF2122/97 ---------RVTYEVFG-PAKTAKIAYLDPDARVHRLDSVSLPWS--VTV
Rv0506|M.tuberculosis_H37Rv ---------RVTYEVFG-PAKTAKIAYLDPDARVHRLDSVSLPWS--VTV
Mflv_3028|M.gilvum_PYR-GCK ---------VVTYEVFG-TGSFAVINYTDLDGLPQRTGQVSLPWT--LTL
Mvan_1058|M.vanbaalenii_PYR-1 ---------VVTYEIFG-SGSTATINYADLDGKPQRTGEVSLPWS--LTL
MUL_2293|M.ulcerans_Agy99 ---------QVTYEVFGPSGTAGSVSYLNKNAEPEEADFSTLPWT--RTI
MMAR_3360|M.marinum_M ---------QVRYEVSG-PGVAEFVSYQTAKGQ-QRATNINLPWS--SEF
MSMEG_4679|M.smegmatis_MC2_155 ---------TATFEVTG-TGTTATVRYSGADRETVRKD-VDLPWTQDITF
MAB_0517|M.abscessus_ATCC_1997 -----HGSKSVTYSVGG-SGSQVNVAYMT-DTEYVRVANISQPWAVTVTR
MAV_0542|M.avium_104 DIEQATKIARAMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQADYSHEV
. * .. : * .
Mb0518|M.bovis_AF2122/97 ETTLPAVSVNLMAQSNADVISCR-------IIVNGAVKDERS-ETSPRAL
Rv0506|M.tuberculosis_H37Rv ETTLPAVSVNLMAQSNADVISCR-------IIVNGAVKDERS-ETSPRAL
Mflv_3028|M.gilvum_PYR-GCK ETTIPSVRPDLLAQGNGQFIGCR-------VTVDGEVEDERT-AEGVNAA
Mvan_1058|M.vanbaalenii_PYR-1 ETTLPSVMPNIMAQGDGQSITCR-------VTVDDEVKDERT-AEGLNAA
MUL_2293|M.ulcerans_Agy99 TTTIPAIIANIVAQGNSDSIGCR-------ITVNGDVKDEQS-AQGHHAQ
MMAR_3360|M.marinum_M T-AFGGQVFVLSAQGQG-SITCR-------ILVDGSVVTEQT-GTGTPGH
MSMEG_4679|M.smegmatis_MC2_155 SGKVKAFVLEVFPLAEDESVSCS-------VTVNGEVVVEKTRAPGEKVL
MAB_0517|M.abscessus_ATCC_1997 TQRDKPLIMNVTMVGEG-TISCS-------ITVDGVTVTEST----DVFA
MAV_0542|M.avium_104 ARDIDDEIRKLIEAAHTEAWEILTEYRDILDTLAGQLLEKETLHRAELES
: .. : . : :
Mb0518|M.bovis_AF2122/97 TSCQVSSG------------------------------------------
Rv0506|M.tuberculosis_H37Rv TSCQVSSG------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK TYCLVKAA------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 TYCLVKAA------------------------------------------
MUL_2293|M.ulcerans_Agy99 TFCLVKAA------------------------------------------
MMAR_3360|M.marinum_M TVCTH---------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 CLGVNPDAGRFG--------------------------------------
MAB_0517|M.abscessus_ATCC_1997 VVCQAPMPG-----------------------------------------
MAV_0542|M.avium_104 IFAGVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPPPAPEPA
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 FKAAIAKASEAAAAARLEADRNANGGNGSHANQGGNRQGPTQPDYGAPAG
Mb0518|M.bovis_AF2122/97 --------------------------------------------------
Rv0506|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2293|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3360|M.marinum_M --------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0542|M.avium_104 WRAPGWPPQQSQQPNYWHPPAQPPYWQQPAHGYPGQQPYPGQQPYPGQPG
Mb0518|M.bovis_AF2122/97 -------------------------------------------------
Rv0506|M.tuberculosis_H37Rv -------------------------------------------------
Mflv_3028|M.gilvum_PYR-GCK -------------------------------------------------
Mvan_1058|M.vanbaalenii_PYR-1 -------------------------------------------------
MUL_2293|M.ulcerans_Agy99 -------------------------------------------------
MMAR_3360|M.marinum_M -------------------------------------------------
MSMEG_4679|M.smegmatis_MC2_155 -------------------------------------------------
MAB_0517|M.abscessus_ATCC_1997 -------------------------------------------------
MAV_0542|M.avium_104 GPAQSGPPQARPPYPPYPPYPPPGQPAPEGGSPDRQDDDVSRSNPPAHG