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MNRKNVIRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAMAQINGDNVKSAQIDDREQQLRLTLKKGN GDTDNSDKVITKYPSGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR MGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPGRYQALGAKIPKGVLLYGPPGTGKT LLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFDQAKQNNPCIIFVDEIDAVGRQRGAGLGGGHD EREQTLNQLLVEMDGFDPRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLAVHSKGKP IAPDADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITSAALEEAVDRVIGGPRRKGRIISEQEKK ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELV FREPTTGAVSDIEQATKIARAMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQADYSHEVARDIDDEIRK LIEAAHTEAWEILTEYRDILDTLAGQLLEKETLHRAELESIFAGVEKRPRLTMFDDFGGRIPSDKPPIKT PGELAIERGEPWPPPAPEPAFKAAIAKASEAAAAARLEADRNANGGNGSHANQGGNRQGPTQPDYGAPAG WRAPGWPPQQSQQPNYWHPPAQPPYWQQPAHGYPGQQPYPGQQPYPGQPGGPAQSGPPQARPPYPPYPPY PPPGQPAPEGGSPDRQDDDVSRSNPPAHG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0542 | hflB | - | 100% (799) | ATP-dependent metallopeptidase HflB |
M. avium 104 | MAV_4716 | - | 1e-45 | 39.62% (260) | cell division protein 48 |
M. avium 104 | MAV_2400 | - | 1e-29 | 36.45% (203) | ATPase, AAA family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3640c | ftsH | 0.0 | 85.41% (802) | membrane-bound protease FTSH (cell division protein) |
M. gilvum PYR-GCK | Mflv_1416 | - | 0.0 | 81.38% (784) | ATP-dependent metalloprotease FtsH |
M. tuberculosis H37Rv | Rv3610c | ftsH | 0.0 | 85.41% (802) | membrane-bound protease FTSH (cell division protein) |
M. leprae Br4923 | MLBr_00222 | ftsH | 0.0 | 86.28% (809) | putative integral membrane peptidase |
M. abscessus ATCC 19977 | MAB_0533 | - | 0.0 | 78.24% (786) | cell division protein FtsH-like protein |
M. marinum M | MMAR_5113 | ftsH | 0.0 | 82.48% (799) | membrane-bound protease FtsH |
M. smegmatis MC2 155 | MSMEG_6105 | - | 0.0 | 81.66% (807) | cell division protein |
M. thermoresistible (build 8) | TH_0991 | ftsH | 0.0 | 79.28% (806) | MEMBRANE-BOUND PROTEASE FTSH (CELL DIVISION PROTEIN) |
M. ulcerans Agy99 | MUL_4192 | ftsH | 0.0 | 82.85% (799) | membrane-bound protease FtsH |
M. vanbaalenii PYR-1 | Mvan_5372 | - | 0.0 | 80.93% (813) | ATP-dependent metalloprotease FtsH |
CLUSTAL 2.0.9 multiple sequence alignment Mb3640c|M.bovis_AF2122/97 ---MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQING Rv3610c|M.tuberculosis_H37Rv ---MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQING MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING MAV_0542|M.avium_104 ---MNRKNVIRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAMAQING MMAR_5113|M.marinum_M ---MNRKNVIRTVTVVAVVVVLGWSFFYFSDDTRGYKPVDTSVAMSQINA MUL_4192|M.ulcerans_Agy99 ---MNRKNVIRTVTAVAVVVVLGWSFFYFSDDTRGYKPVDTSVAMSQINA Mflv_1416|M.gilvum_PYR-GCK ---MNRKNVIRTLTVIAVVLLLGWSFFYFSDDTRGYKPVDTTIAIAQING Mvan_5372|M.vanbaalenii_PYR-1 ---MNRKNVIRTLTVIAVVLLLGWSFFYFSDDTRGYKPVDTSVAMAQISG MSMEG_6105|M.smegmatis_MC2_155 ---MNRKNVIRTLTVIGVVLLLGWSFFYFSDDTRGYKPVDTTVALAQIRG TH_0991|M.thermoresistible__bu ---MNRKTVIRTLTIVAVVLLLGWSFFYFGDDTREYKPVDTSVALAQIQA MAB_0533|M.abscessus_ATCC_1997 ---MNRTNVFRTLGVIVVVLLLGWSFFYFSDDTRGYKPVDTTVAIKQIDT ***..* * : : **::********.**** ** ***::*: ** Mb3640c|M.bovis_AF2122/97 DNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSA Rv3610c|M.tuberculosis_H37Rv DNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSA MLBr_00222|M.leprae_Br4923 HNVKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSA MAV_0542|M.avium_104 DNVKSAQIDDREQQLRLTLKKGNGDTDNSDKVITKYPSGYAVDLFNALSA MMAR_5113|M.marinum_M DNVKSAQIDDREQQLRLVLKKSSSDTDGSDKVITKYPTGYAVDLFNALTA MUL_4192|M.ulcerans_Agy99 DNAKSAQIDDREQQLRLVLKKSSSDTDGSDKVITKYPTGYAVDLFNALTA Mflv_1416|M.gilvum_PYR-GCK DNVNSAQIDDREQQLRLELKNGNGDTENSTQILTKYPTGYGATLFESLQD Mvan_5372|M.vanbaalenii_PYR-1 DNVKSAQIDDREQQLRLELKNGNGDTENSDKIITKYPTGYGVPLFEALQA MSMEG_6105|M.smegmatis_MC2_155 DNVNSAQIDDREQQVRLDLKSGNGDTENSDKIITKYPTGYGVTLFNALQD TH_0991|M.thermoresistible__bu DNVDSAQIDDREQQVRLDLKNANSDTGDSDKIIAKYPTGYAVPLFDALQD MAB_0533|M.abscessus_ATCC_1997 DNVKSARIDDREQQLRLDLKAANGDTEGKDKVITKYPTGYGVPLLEKLNG .*..**:*******:** ** ...:* .. ::::***:**.. *:: * Mb3640c|M.bovis_AF2122/97 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG Rv3610c|M.tuberculosis_H37Rv KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MLBr_00222|M.leprae_Br4923 KNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MAV_0542|M.avium_104 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MMAR_5113|M.marinum_M KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG MUL_4192|M.ulcerans_Agy99 KNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGAR-MGFGFG Mflv_1416|M.gilvum_PYR-GCK KNIKTNTVVNQSSIFGTLLIYMLPLLLLVALFVLFSRMQSGGR-MGFGFG Mvan_5372|M.vanbaalenii_PYR-1 KNTKINTVVNQSSILGTLLIYMLPLLLLVGLFVMFSRMQTGGR-MGFGFG MSMEG_6105|M.smegmatis_MC2_155 KGAKTNTVVNQGSVFGTLLIYMLPLLLLVALFVMFSRMQTGGR-MGFGFG TH_0991|M.thermoresistible__bu KNAKVNTVVNQGSVLGTLLIYMLPLLLLVALFVFFMRMQSGGR-MGFGFG MAB_0533|M.abscessus_ATCC_1997 KGAAVNTTVNQGSILGSLLLYLLPVILLVVLFFAFSRMQSGGRGMGFGFG *. .*.**:.*::* **:*:**::*** **. * *** *.* ****** Mb3640c|M.bovis_AF2122/97 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Rv3610c|M.tuberculosis_H37Rv KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MLBr_00222|M.leprae_Br4923 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGAKIP MAV_0542|M.avium_104 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPGRYQALGAKIP MMAR_5113|M.marinum_M KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MUL_4192|M.ulcerans_Agy99 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Mflv_1416|M.gilvum_PYR-GCK KSKAKMLSKDMPRTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP Mvan_5372|M.vanbaalenii_PYR-1 KSKAKMLGKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MSMEG_6105|M.smegmatis_MC2_155 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP TH_0991|M.thermoresistible__bu KSKAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP MAB_0533|M.abscessus_ATCC_1997 KSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIP **:** *.****:************************** ***:****** Mb3640c|M.bovis_AF2122/97 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Rv3610c|M.tuberculosis_H37Rv KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MLBr_00222|M.leprae_Br4923 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MAV_0542|M.avium_104 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MMAR_5113|M.marinum_M KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MUL_4192|M.ulcerans_Agy99 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Mflv_1416|M.gilvum_PYR-GCK KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD Mvan_5372|M.vanbaalenii_PYR-1 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MSMEG_6105|M.smegmatis_MC2_155 KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD TH_0991|M.thermoresistible__bu KGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD MAB_0533|M.abscessus_ATCC_1997 RGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRD :************************************************* Mb3640c|M.bovis_AF2122/97 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Rv3610c|M.tuberculosis_H37Rv LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MLBr_00222|M.leprae_Br4923 LFDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGF MAV_0542|M.avium_104 LFDQAKQNNPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MMAR_5113|M.marinum_M LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MUL_4192|M.ulcerans_Agy99 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Mflv_1416|M.gilvum_PYR-GCK LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF Mvan_5372|M.vanbaalenii_PYR-1 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MSMEG_6105|M.smegmatis_MC2_155 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF TH_0991|M.thermoresistible__bu LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF MAB_0533|M.abscessus_ATCC_1997 LFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF **:*****.*****************:*********************** Mb3640c|M.bovis_AF2122/97 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS Rv3610c|M.tuberculosis_H37Rv GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MLBr_00222|M.leprae_Br4923 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MAV_0542|M.avium_104 DPRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLAVHS MMAR_5113|M.marinum_M GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRRAVLRVHS MUL_4192|M.ulcerans_Agy99 GDRAGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRRAVLRVHS Mflv_1416|M.gilvum_PYR-GCK GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSSPDLAGRRAVLKVHS Mvan_5372|M.vanbaalenii_PYR-1 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHS MSMEG_6105|M.smegmatis_MC2_155 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLKVHS TH_0991|M.thermoresistible__bu GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRKAVLRVHA MAB_0533|M.abscessus_ATCC_1997 GDRQGVILIAATNRPDILDPALLRPGRFDRQIPVSSPDLAGRKAVLKVHS . * ******************************:.******:*** **: Mb3640c|M.bovis_AF2122/97 KGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL Rv3610c|M.tuberculosis_H37Rv KGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL MLBr_00222|M.leprae_Br4923 KGKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGPAL MAV_0542|M.avium_104 KGKPIAPDADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITSAAL MMAR_5113|M.marinum_M KGKPIADGADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL MUL_4192|M.ulcerans_Agy99 KGKPIADGADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPAL Mflv_1416|M.gilvum_PYR-GCK QGKPIAEDADLEGLAKRTVGMSGADLANVINEAALLTARENGTIITGPAL Mvan_5372|M.vanbaalenii_PYR-1 QGKPIADDADLDGLAKRTVGMSGADLANVINEAALLTARENGTIITGPAL MSMEG_6105|M.smegmatis_MC2_155 QGKPIAPDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGPAL TH_0991|M.thermoresistible__bu QGKPLAPDVDLDGLAKRTVGMSGADLANVINEAALLTARENGTMITGPAL MAB_0533|M.abscessus_ATCC_1997 AGKPFGPDVDFDGLAKRTVGMSGADLANVINEAALLTARENGTVITAAAL ***:. ..*::*********:*******:************ :**..** Mb3640c|M.bovis_AF2122/97 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT Rv3610c|M.tuberculosis_H37Rv EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT MLBr_00222|M.leprae_Br4923 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT MAV_0542|M.avium_104 EEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVT MMAR_5113|M.marinum_M EEAVDRVIGGPRRKGRIISEHEKKITAYHEGGHTLAAWAMPDIDPVYKVT MUL_4192|M.ulcerans_Agy99 EEAVDRVIGGPRRKGRIISEHEKKITAYHEGGHTLAAWAMPDIDPVYKVT Mflv_1416|M.gilvum_PYR-GCK EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVT Mvan_5372|M.vanbaalenii_PYR-1 EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIDPIYKVT MSMEG_6105|M.smegmatis_MC2_155 EEAVDRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVT TH_0991|M.thermoresistible__bu EEAVDRVVGGPRRKSRLISELEKKITAYHEGGHTLAAWAMPDIEPIYKVT MAB_0533|M.abscessus_ATCC_1997 EESVDRVVGGPRRKGRIISEHEKKITAYHEAGHTLAAWAMPDIERVYKVT **:****:******.*:*** *********.************: :**** Mb3640c|M.bovis_AF2122/97 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT Rv3610c|M.tuberculosis_H37Rv ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MLBr_00222|M.leprae_Br4923 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MAV_0542|M.avium_104 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MMAR_5113|M.marinum_M ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT MUL_4192|M.ulcerans_Agy99 ILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTT Mflv_1416|M.gilvum_PYR-GCK ILARGRTGGHAMAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT Mvan_5372|M.vanbaalenii_PYR-1 ILARGRTGGHAMSVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT MSMEG_6105|M.smegmatis_MC2_155 ILARGRTGGHAVAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT TH_0991|M.thermoresistible__bu ILARGRTGGHAVAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTT MAB_0533|M.abscessus_ATCC_1997 ILARGRTGGHAIAVPEDDKGLATRSEMIAQLVFAMGGRAAEELVFREPTT ***********::***:**** *******:******************** Mb3640c|M.bovis_AF2122/97 GAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDY Rv3610c|M.tuberculosis_H37Rv GAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDY MLBr_00222|M.leprae_Br4923 GAVSDIEKATKIARSMVTEFGMSSKLGAVRYGSEHGDPFLGRTMGTQADY MAV_0542|M.avium_104 GAVSDIEQATKIARAMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQADY MMAR_5113|M.marinum_M GAVSDIEQATKVARAMVTEYGMSARLGAVKYGTEHGDPFLGRSMGTQSDY MUL_4192|M.ulcerans_Agy99 GAVSDIEQATKVARAMVTEYGMSARLGAVKYGTEHGDPFLGRSMGTQSDY Mflv_1416|M.gilvum_PYR-GCK GASSDIDQATKIARAMVTEYGMSSKLGAVRYGSEHGDPFLGRTMGNQADY Mvan_5372|M.vanbaalenii_PYR-1 GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTQADY MSMEG_6105|M.smegmatis_MC2_155 GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTQADY TH_0991|M.thermoresistible__bu GAVSDIEQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTHADY MAB_0533|M.abscessus_ATCC_1997 GAVSDIEQATKKARAMVTEFGMSAKLGAVRYGTEHGDPFLGRTMGTQADY ** ***::*** **:****:***::****:**:*********:**.:.** Mb3640c|M.bovis_AF2122/97 SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP Rv3610c|M.tuberculosis_H37Rv SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP MLBr_00222|M.leprae_Br4923 SHEVARDIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRP MAV_0542|M.avium_104 SHEVARDIDDEIRKLIEAAHTEAWEILTEYRDILDTLAGQLLEKETLHRA MMAR_5113|M.marinum_M SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGQLLEKETLHRP MUL_4192|M.ulcerans_Agy99 SHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGQLLEKETLHRP Mflv_1416|M.gilvum_PYR-GCK SHEVAQIIDDEIRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRV Mvan_5372|M.vanbaalenii_PYR-1 SHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRV MSMEG_6105|M.smegmatis_MC2_155 SHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDVLDILAGELLEKETLHRA TH_0991|M.thermoresistible__bu SHEVARDIDDEIRKLIEAAHTEAWEILTEYRDVLDVLAGELLEKETLHRR MAB_0533|M.abscessus_ATCC_1997 SHEVAREIDEEVRNLIEAAHTEAWAILTEYRDVLDTLAGALLEKETVVRK *****: **:*:*:********** *******:** *** ******: * Mb3640c|M.bovis_AF2122/97 ELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV Rv3610c|M.tuberculosis_H37Rv ELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV MLBr_00222|M.leprae_Br4923 ELEGIFASVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPV MAV_0542|M.avium_104 ELESIFAGVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPPPA MMAR_5113|M.marinum_M ELESIFSDVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPM MUL_4192|M.ulcerans_Agy99 ELESIFSDVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPM Mflv_1416|M.gilvum_PYR-GCK ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEPWPKPV Mvan_5372|M.vanbaalenii_PYR-1 ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEPWPKPL MSMEG_6105|M.smegmatis_MC2_155 ELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAMERGEPWPPPV TH_0991|M.thermoresistible__bu ELEVILADVKKRPRLTMFDDFGGRTPSDKPPIKTPGELAMERGEPWPKPE MAB_0533|M.abscessus_ATCC_1997 ELEEIFSGVQRRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPPPV *** *:..*::************* **************:******* * Mb3640c|M.bovis_AF2122/97 PEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQ---YGS Rv3610c|M.tuberculosis_H37Rv PEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQ---YGS MLBr_00222|M.leprae_Br4923 PEPAFKAAIARASQAAEASHQAAQSDTDGPPGQGANGSHAGDRQR-QHGP MAV_0542|M.avium_104 PEPAFKAAIAKASEAAAAARLEADRNANGGNGSHAN--QGGNRQ----GP MMAR_5113|M.marinum_M PEPAFKQAIAQATQAAQAA--QAAQSASEGTGRGPNGSRGADAN----PG MUL_4192|M.ulcerans_Agy99 PEPAFKQAIAQAT--------QAAQSASEGTGRGPNGSRGADAN----PG Mflv_1416|M.gilvum_PYR-GCK PEPAFKTAIAQASRAAAEAAPKNGGNGANGAH-APG-------------- Mvan_5372|M.vanbaalenii_PYR-1 PEPAFKTAIAQASRAAAEQAQKNGGNGSQASNGVPGG------------P MSMEG_6105|M.smegmatis_MC2_155 PEPAFKAAIAAANREAEKRNGTNGAP-SNGAP-APAG------------P TH_0991|M.thermoresistible__bu PEPAFKVAIAEATRAAEAASGQNGQNGHNGTPGPTGPNGTPSAPAQQPAP MAB_0533|M.abscessus_ATCC_1997 PEPAFKKAIAEQAAAAAPANGVPPAPAGPHGHLPNGQGG-------QPVP ****** *** Mb3640c|M.bovis_AF2122/97 TQPDYGAPAGWHAPGWPPRSS--------HRPS---YSGEPAPTYPGQ-- Rv3610c|M.tuberculosis_H37Rv TQPDYGAPAGWHAPGWPPRSS--------HRPS---YSGEPAPTYPGQ-- MLBr_00222|M.leprae_Br4923 TQPDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQSPYWPQPAPSYPGQAP MAV_0542|M.avium_104 TQPDYGAPAGWRAPGWPPQQSQQP--NYWHPPAQPPYWQQPAHGYPGQQP MMAR_5113|M.marinum_M SHPDYGAPAGWRAPGWPPPSE----------------RPQPSGYSPDQ-- MUL_4192|M.ulcerans_Agy99 SHPDYGAPAGWRAPGWPPPSE----------------RPQPSGYSPDQ-- Mflv_1416|M.gilvum_PYR-GCK --PDYGAPAGWHAPGWPPPPGGPQQQQPPQQ---QGYWYPGPPQQQGWQG Mvan_5372|M.vanbaalenii_PYR-1 TQPDYGAPAGWHAPGWPPQAGGP---HPPQP---QGYWYP-PPPPSGWQG MSMEG_6105|M.smegmatis_MC2_155 TQPDYGAPAGWHAPGWPPPQQSQQPGYQPQ----QGYWYP-PPHPSGWQ- TH_0991|M.thermoresistible__bu VVPDYGAPAGWHAPGWPPQPTPQQQPPPYQQP--HGQWYP-PQQQPGWQ- MAB_0533|M.abscessus_ATCC_1997 PGVNYGAPAGWHAPGWPPPGQAPHP-------------------QPGYQ- :****.**:****** . Mb3640c|M.bovis_AF2122/97 -----PYP--------------------------TGQADPGSDESSAEQD Rv3610c|M.tuberculosis_H37Rv -----PYP--------------------------TGQADPGSDESSAEQD MLBr_00222|M.leprae_Br4923 P----PYPS----------------YPPCPSYPPPGQSAPDAGKPPAQLD MAV_0542|M.avium_104 YPGQQPYPGQPGGPAQSGPPQARPPYPPYPPYPPPGQPAPEGG-SPDRQD MMAR_5113|M.marinum_M --------------------------------------PSDTDESSEQQD MUL_4192|M.ulcerans_Agy99 --------------------------------------PSDTDESSEQQD Mflv_1416|M.gilvum_PYR-GCK NAPTPAYPG----------------YPPYQPYPQPGQHAPHGGAPAPNPT Mvan_5372|M.vanbaalenii_PYR-1 APQAPAYPG----------------YPPYQPHSQPGQPAPHGGAAAASPK MSMEG_6105|M.smegmatis_MC2_155 --QPQPYP--------------------YQPYPHPGQQGTS--PEHGRPS TH_0991|M.thermoresistible__bu -QQQQPYPSQ---------------YSPYQPYPQPSPPAPPGGAAPND-- MAB_0533|M.abscessus_ATCC_1997 -----PYPP--------------------QPYPYP----------VPTPH Mb3640c|M.bovis_AF2122/97 DEVSRTKP-AHG---------------------- Rv3610c|M.tuberculosis_H37Rv DEVSRTKP-AHG---------------------- MLBr_00222|M.leprae_Br4923 EGVSPSNPPAHG---------------------- MAV_0542|M.avium_104 DDVSRSNPPAHG---------------------- MMAR_5113|M.marinum_M RDVSRSNPPAHG---------------------- MUL_4192|M.ulcerans_Agy99 RDVSRSNPPAHG---------------------- Mflv_1416|M.gilvum_PYR-GCK DDPGQDRGRENGHRDTERRDTDRGDTNRNGPANG Mvan_5372|M.vanbaalenii_PYR-1 EDPGHEGGGENGRSAP--------------PSNG MSMEG_6105|M.smegmatis_MC2_155 EQSGQDDGHTGDRSNP----------------HG TH_0991|M.thermoresistible__bu QESGQDPNRTNPPGQG------------------ MAB_0533|M.abscessus_ATCC_1997 QQPGPAPDEGSESKG------------------- .